{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:51:36Z","timestamp":1782885096922,"version":"3.54.5"},"reference-count":63,"publisher":"Royal Society of Chemistry (RSC)","issue":"9","license":[{"start":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T00:00:00Z","timestamp":1597968000000},"content-version":"am","delay-in-days":598,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>\u03b1-Lipoic acid supplementation may improve insulin sensitivity in pre-diabetic subjects but is not effective in modulating serum lipids.<\/p>","DOI":"10.1039\/c9fo00390h","type":"journal-article","created":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T11:23:59Z","timestamp":1566386639000},"page":"5732-5738","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Metabolic effects of \u03b1-lipoic acid supplementation in pre-diabetics: a randomized, placebo-controlled pilot study"],"prefix":"10.1039","volume":"10","author":[{"given":"Luc E.","family":"Gosselin","sequence":"first","affiliation":[{"name":"Exercise and Nutrition Sciences"},{"name":"School of Public Health and Health Professions"},{"name":"State University of New York at Buffalo"},{"name":"Buffalo"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Chrapowitzky","sequence":"additional","affiliation":[{"name":"Exercise and Nutrition Sciences"},{"name":"School of Public Health and Health Professions"},{"name":"State University of New York at Buffalo"},{"name":"Buffalo"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1834-7083","authenticated-orcid":false,"given":"Todd C.","family":"Rideout","sequence":"additional","affiliation":[{"name":"Exercise and Nutrition Sciences"},{"name":"School of Public Health and Health Professions"},{"name":"State University of New York at Buffalo"},{"name":"Buffalo"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2019]]},"reference":[{"key":"C9FO00390H-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"517","DOI":"10.7326\/M13-2411","volume":"160","author":"Selvin","year":"2014","journal-title":"Ann. Intern. Med."},{"issue":"4","key":"C9FO00390H-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.2337\/dc12-0227","volume":"36","author":"Yang","year":"2013","journal-title":"Diabetes Care"},{"key":"C9FO00390H-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.jacc.2011.08.080","volume":"59","author":"Grundy","year":"2012","journal-title":"J. Am. Coll. Cardiol."},{"key":"C9FO00390H-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.cnur.2017.07.011","volume":"52","author":"Wilson","year":"2017","journal-title":"Nurs. Clin. North Am."},{"key":"C9FO00390H-(cit5)\/*[position()=1]","first-page":"18","volume":"64","author":"Kansal","year":"2016","journal-title":"J. Assoc. Physicians India"},{"key":"C9FO00390H-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.atherosclerosis.2016.11.020","volume":"256","author":"Andreozzi","year":"2017","journal-title":"Atherosclerosis"},{"key":"C9FO00390H-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.numecd.2014.01.013","volume":"24","author":"Calanna","year":"2014","journal-title":"Nutr., Metab. Cardiovasc. Dis."},{"key":"C9FO00390H-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4330\/wjc.v4.i3.77","volume":"4","author":"Affuso","year":"2012","journal-title":"World J. Cardiol."},{"key":"C9FO00390H-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1089\/met.2011.0081","volume":"10","author":"Kelley","year":"2012","journal-title":"Metab. Syndr. Relat. Disord."},{"key":"C9FO00390H-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1017\/S0954422412000236","volume":"26","author":"Marinangeli","year":"2013","journal-title":"Nutr. Res. Rev."},{"key":"C9FO00390H-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.bbagen.2009.07.026","volume":"1790","author":"Shay","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"C9FO00390H-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.fct.2013.01.055","volume":"61","author":"Georgakouli","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"C9FO00390H-(cit13)\/*[position()=1]","first-page":"139","volume":"60","author":"Zembron-Lacny","year":"2009","journal-title":"J. Physiol. Pharmacol."},{"issue":"11","key":"C9FO00390H-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"pii: E1802","DOI":"10.3390\/ijms17111802","volume":"17","author":"Derosa","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"C9FO00390H-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/sc.2015.35","volume":"53","author":"Mohammadi","year":"2015","journal-title":"Spinal Cord"},{"key":"C9FO00390H-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"34","DOI":"10.4103\/ijpvm.IJPVM_32_17","volume":"9","author":"Mohammadi","year":"2018","journal-title":"Int. J. Prev. Med."},{"key":"C9FO00390H-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0891-5849(99)00089-1","volume":"27","author":"Jacob","year":"1999","journal-title":"Free Radicals Biol. Med."},{"key":"C9FO00390H-(cit18)\/*[position()=1]","first-page":"12","volume":"21","author":"Porasuphatana","year":"2012","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"C9FO00390H-(cit19)\/*[position()=1]","first-page":"584","volume":"32","author":"Ansar","year":"2011","journal-title":"Saudi Med. J."},{"key":"C9FO00390H-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fphar.2011.00069","volume":"2","author":"Golbidi","year":"2011","journal-title":"Front. Pharmacol."},{"issue":"1","key":"C9FO00390H-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"85.e1","DOI":"10.1016\/j.amjmed.2010.08.005","volume":"124","author":"Koh","year":"2011","journal-title":"Am. J. Med."},{"key":"C9FO00390H-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/oby.20966","volume":"23","author":"Huerta","year":"2015","journal-title":"Obesity"},{"key":"C9FO00390H-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/YIC.0000000000000132","volume":"31","author":"Kim","year":"2016","journal-title":"Int. Clin. Psychopharmacol."},{"key":"C9FO00390H-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.jacl.2014.07.007","volume":"8","author":"Jacobson","year":"2014","journal-title":"J. Clin. Lipidol."},{"key":"C9FO00390H-(cit25)\/*[position()=1]","first-page":"e1082","volume":"139","author":"Grundy","year":"2019","journal-title":"Circulation"},{"key":"C9FO00390H-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"E736","DOI":"10.1152\/ajpendo.00183.2011","volume":"301","author":"Xiao","year":"2011","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"C9FO00390H-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1177\/193229681000400218","volume":"4","author":"Masharani","year":"2010","journal-title":"J. Diabetes Sci. Technol."},{"key":"C9FO00390H-(cit28)\/*[position()=1]","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/09513590.2018.1519795","author":"Aslfalah","year":"2018","journal-title":"Gynecol. Endocrinol."},{"key":"C9FO00390H-(cit29)\/*[position()=1]","first-page":"45","volume":"56","author":"Hejazi","year":"2018","journal-title":"Asian J. Anesthesiol."},{"key":"C9FO00390H-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s40618-017-0782-z","volume":"41","author":"Genazzani","year":"2018","journal-title":"J. Endocrinol. Invest."},{"key":"C9FO00390H-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.metabol.2018.07.002","volume":"87","author":"Akbari","year":"2018","journal-title":"Metabolism"},{"key":"C9FO00390H-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e90863","DOI":"10.1371\/journal.pone.0090863","volume":"9","author":"Carrier","year":"2014","journal-title":"PLoS One"},{"key":"C9FO00390H-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nm1061","volume":"10","author":"Kim","year":"2004","journal-title":"Nat. Med."},{"key":"C9FO00390H-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jdiacomp.2009.09.007","volume":"25","author":"Kandeil","year":"2011","journal-title":"J. Diabetes Complications"},{"key":"C9FO00390H-(cit35)\/*[position()=1]","first-page":"47","volume":"14","author":"Budin","year":"2007","journal-title":"Malays. J. Med. Sci."},{"key":"C9FO00390H-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/S0026-0495(99)90112-9","volume":"48","author":"Khamaisi","year":"1999","journal-title":"Metabolism"},{"key":"C9FO00390H-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s10863-012-9460-1","volume":"44","author":"Qin","year":"2012","journal-title":"J. Bioenerg. Biomembr."},{"key":"C9FO00390H-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"E529","DOI":"10.1152\/ajpendo.00013.2004","volume":"287","author":"Saengsirisuwan","year":"2004","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"C9FO00390H-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1016\/S0140-6736(12)60283-9","volume":"379","author":"Tabak","year":"2012","journal-title":"Lancet"},{"key":"C9FO00390H-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1038\/oby.2012.32","volume":"20","author":"Valdecantos","year":"2012","journal-title":"Obesity"},{"key":"C9FO00390H-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1016\/j.jnutbio.2011.11.011","volume":"23","author":"Valdecantos","year":"2012","journal-title":"J. Nutr. Biochem."},{"key":"C9FO00390H-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.nut.2008.02.002","volume":"24","author":"Yang","year":"2008","journal-title":"Nutrition"},{"key":"C9FO00390H-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/nchembio.610","volume":"7","author":"Carling","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"C9FO00390H-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4162\/nrp.2012.6.3.195","volume":"6","author":"Seo","year":"2012","journal-title":"Nutr. Res. Pract."},{"key":"C9FO00390H-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.abb.2009.01.024","volume":"485","author":"Butler","year":"2009","journal-title":"Arch. Biochem. Biophys."},{"key":"C9FO00390H-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1002\/oby.20846","volume":"22","author":"Fernandez-Galilea","year":"2014","journal-title":"Obesity"},{"key":"C9FO00390H-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/S0891-5849(99)00155-0","volume":"27","author":"Marangon","year":"1999","journal-title":"Free Radicals Biol. Med."},{"key":"C9FO00390H-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/S0891-5849(99)00011-8","volume":"26","author":"Borcea","year":"1999","journal-title":"Free Radical Biol. Med."},{"key":"C9FO00390H-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.diabres.2011.02.010","volume":"92","author":"de Oliveira","year":"2011","journal-title":"Diabetes Res. Clin. Pract."},{"key":"C9FO00390H-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3844\/ajptsp.2010.152.158","volume":"5","author":"El-Nabarawy","year":"2010","journal-title":"Am. J. Pharmacol. Toxicol."},{"issue":"Suppl 1","key":"C9FO00390H-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.archger.2009.09.022","volume":"49","author":"Gianturco","year":"2009","journal-title":"Arch. Gerontol. Geriatr."},{"key":"C9FO00390H-(cit52)\/*[position()=1]","first-page":"122","volume":"12","author":"Okanovic","year":"2015","journal-title":"Med. Glas."},{"key":"C9FO00390H-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/oby.20966","volume":"23","author":"Huerta","year":"2015","journal-title":"Obesity"},{"key":"C9FO00390H-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.clnu.2017.06.002","volume":"37","author":"Namazi","year":"2018","journal-title":"Clin. Nutr."},{"key":"C9FO00390H-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/cen.13303","volume":"86","author":"Li","year":"2017","journal-title":"Clin. Endocrinol."},{"key":"C9FO00390H-(cit56)\/*[position()=1]","first-page":"298","volume":"7","author":"El-Farok","year":"2013","journal-title":"Global J. Pharmacol."},{"key":"C9FO00390H-(cit57)\/*[position()=1]","volume-title":"Does Alpha-Lipoic Acid Comsumption Improve Lipid Profile In Patients With Stroke? A Randomized, Double Blind, Placebo-Controlled Clinical Trial","author":"Mohammadi","year":"2017","unstructured":"V. Mohammadi  ,  F.Khorvash ,  A.Feizi  and  G.Askari ,  Does Alpha-Lipoic Acid Comsumption Improve Lipid Profile In Patients With Stroke? A Randomized, Double Blind, Placebo-Controlled Clinical Trial ,  2017"},{"key":"C9FO00390H-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1053\/j.jrn.2011.06.005","volume":"22","author":"Khabbazi","year":"2012","journal-title":"J. Renal Nutr."},{"key":"C9FO00390H-(cit59)\/*[position()=1]","first-page":"3715","volume":"18","author":"Zhao","year":"2014","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"C9FO00390H-(cit60)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1038\/oby.2011.121","volume":"19","author":"Zhang","year":"2011","journal-title":"Obesity"},{"key":"C9FO00390H-(cit61)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"25","DOI":"10.7453\/gahmj.2013.011","volume":"3","author":"Vigil","year":"2014","journal-title":"Glob. Adv. Health Med."},{"key":"C9FO00390H-(cit62)\/*[position()=1]","first-page":"625","volume":"36","author":"Teichert","year":"1998","journal-title":"Int. J. Clin. Pharmacol. Ther."},{"key":"C9FO00390H-(cit63)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S1734-1140(11)70600-4","volume":"63","author":"Goraca","year":"2011","journal-title":"Pharmacol. Rep."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2019\/FO\/C9FO00390H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:35:14Z","timestamp":1782880514000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/10\/9\/5732-5738\/645492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":63,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9,18]]}},"URL":"https:\/\/doi.org\/10.1039\/c9fo00390h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Todd C. Rideout (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-1834-7083","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 25 February 2019; Accepted 20 August 2019;  Accepted Manuscript published 21 August 2019;  Advance Article published 27 August 2019;  Version of Record published 18 September 2019","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}