{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:47:42Z","timestamp":1790178462013,"version":"4.1.0"},"reference-count":109,"publisher":"Royal Society of Chemistry (RSC)","issue":"11","license":[{"start":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T00:00:00Z","timestamp":1602028800000},"content-version":"am","delay-in-days":645,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"crossref","award":["201604020150"],"award-info":[{"award-number":["201604020150"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>The effects of diosgenin are discussed with respect to endothelial dysfunction, lipid profile, macrophage foam cell formation, VSMC viability, thrombosis and inflammation during the formation of atherosclerosis.<\/p>","DOI":"10.1039\/c9fo00749k","type":"journal-article","created":{"date-parts":[[2019,10,6]],"date-time":"2019-10-06T22:03:31Z","timestamp":1570399411000},"page":"7022-7036","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Effects of diosgenin and its derivatives on atherosclerosis"],"prefix":"10.1039","volume":"10","author":[{"given":"Fang-Chun","family":"Wu","sequence":"first","affiliation":[{"name":"College of Food and Bioengineering"},{"name":"South China University of Technology"},{"name":"Guangzhou"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3361-6149","authenticated-orcid":false,"given":"Jian-Guo","family":"Jiang","sequence":"additional","affiliation":[{"name":"College of Food and Bioengineering"},{"name":"South China University of Technology"},{"name":"Guangzhou"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2019]]},"reference":[{"key":"C9FO00749K-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.3390\/nu10111724","volume":"10","author":"Tsui","year":"2018","journal-title":"Nutrients"},{"key":"C9FO00749K-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"E67","DOI":"10.1161\/CIR.0000000000000558","volume":"137","author":"Benjamin","year":"2018","journal-title":"Circulation"},{"key":"C9FO00749K-(cit3)\/*[position()=1]","author":"WHO","unstructured":"WHO  , Fact sheet on cardiovascular diseases,  https:\/\/www.who.int\/mediacentre\/factsheets\/fs317\/zh\/"},{"key":"C9FO00749K-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1016\/j.biotechadv.2015.08.001","volume":"33","author":"Atanasov","year":"2015","journal-title":"Biotechnol. Adv."},{"key":"C9FO00749K-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1080\/14786410701192827","volume":"21","author":"Jiang","year":"2007","journal-title":"Nat. Prod. Res."},{"key":"C9FO00749K-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1002\/jssc.200800744","volume":"32","author":"Yang","year":"2009","journal-title":"J. Sep. Sci."},{"key":"C9FO00749K-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9968","DOI":"10.1021\/acs.jafc.8b03040","volume":"66","author":"Hashidume","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"C9FO00749K-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s13020-018-0215-8","volume":"13","author":"Shen","year":"2018","journal-title":"Chin. Med."},{"key":"C9FO00749K-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1080\/15384101.2019.1568748","volume":"18","author":"Long","year":"2019","journal-title":"Cell Cycle"},{"key":"C9FO00749K-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3390\/molecules22010163","volume":"22","author":"Pi","year":"2017","journal-title":"Molecules"},{"key":"C9FO00749K-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"566","DOI":"10.12965\/jer.1836340.170","volume":"14","author":"Lee","year":"2018","journal-title":"J. Exerc. Rehabil."},{"key":"C9FO00749K-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1159\/000484396","volume":"43","author":"Yang","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"key":"C9FO00749K-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/01635580802357352","volume":"61","author":"Raju","year":"2009","journal-title":"Nutr. Cancer"},{"key":"C9FO00749K-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1271\/bbb.70472","volume":"71","author":"Son","year":"2007","journal-title":"Biosci., Biotechnol., Biochem."},{"key":"C9FO00749K-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1002\/jcp.27254","volume":"234","author":"Tang","year":"2019","journal-title":"J. Cell Physiol."},{"key":"C9FO00749K-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0092-8674(01)00238-0","volume":"104","author":"Glass","year":"2001","journal-title":"Cell"},{"key":"C9FO00749K-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"151","DOI":"10.3389\/fcvm.2018.00151","volume":"5","author":"Li","year":"2018","journal-title":"Front. Cardiovasc. Med."},{"key":"C9FO00749K-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1093\/eurheartj\/eht351","volume":"34","author":"Gutierrez","year":"2013","journal-title":"Eur. Heart J."},{"key":"C9FO00749K-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1161\/CIRCULATIONAHA.105.602532","volume":"113","author":"Forstermann","year":"2006","journal-title":"Circulation"},{"key":"C9FO00749K-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1161\/01.RES.0000255691.76142.4a","volume":"100","author":"Aird","year":"2007","journal-title":"Circ. Res."},{"key":"C9FO00749K-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1177\/2040622311430006","volume":"3","author":"Habauzit","year":"2012","journal-title":"Ther. Adv. Chronic Dis."},{"key":"C9FO00749K-(cit22)\/*[position()=1]","volume-title":"Vascular and Platelet Effects of Cocoa","author":"Sudano","year":"2012","unstructured":"I. Sudano  ,  A. J.Flammer ,  G.Noll  and  R.Corti ,  Vascular and Platelet Effects of Cocoa ,  2012"},{"key":"C9FO00749K-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1210\/edrv.22.1.0417","volume":"22","author":"Calles-Escandon","year":"2001","journal-title":"Endocr. Rev."},{"key":"C9FO00749K-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s11892-003-0019-8","volume":"3","author":"Deedwania","year":"2003","journal-title":"Curr. Diabetes Rep."},{"key":"C9FO00749K-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1073\/pnas.041359198","volume":"98","author":"Fukumura","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C9FO00749K-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.niox.2013.09.004","volume":"35","author":"Lei","year":"2013","journal-title":"Nitric Oxide \u2013 Biol. Chem."},{"key":"C9FO00749K-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jsbmb.2015.07.005","volume":"155","author":"Chen","year":"2016","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"C9FO00749K-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.ejphar.2014.07.026","volume":"740","author":"Ahmed","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"C9FO00749K-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11010-013-1588-8","volume":"378","author":"Manivannan","year":"2013","journal-title":"Mol. Cell. Biochem."},{"key":"C9FO00749K-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/FJC.0000000000000308","volume":"66","author":"Roghani-Dehkordi","year":"2015","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"C9FO00749K-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.atherosclerosis.2012.06.012","volume":"223","author":"Liu","year":"2012","journal-title":"Atherosclerosis"},{"key":"C9FO00749K-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1253\/circj.CJ-08-1102","volume":"73","author":"Higashi","year":"2009","journal-title":"Circ. J."},{"key":"C9FO00749K-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s11010-013-1788-2","volume":"384","author":"Manivannan","year":"2013","journal-title":"Mol. Cell. Biochem."},{"key":"C9FO00749K-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-2797(97)00146-4","volume":"111","author":"Anderson","year":"1998","journal-title":"Chem.-Biol. Interact."},{"key":"C9FO00749K-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3390\/ijms19030798","volume":"19","author":"Szabo","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"C9FO00749K-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.cbi.2013.08.014","volume":"206","author":"Sangeetha","year":"2013","journal-title":"Chem.-Biol. Interact."},{"key":"C9FO00749K-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.cbi.2010.02.005","volume":"184","author":"Gong","year":"2010","journal-title":"Chem.-Biol. Interact."},{"key":"C9FO00749K-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1042\/CS20120536","volume":"124","author":"Bijland","year":"2013","journal-title":"Clin. Sci."},{"key":"C9FO00749K-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1161\/ATVBAHA.111.237453","volume":"31","author":"Zhang","year":"2011","journal-title":"Arterioscler., Thromb., Vasc. Biol."},{"key":"C9FO00749K-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1161\/01.RES.84.9.1085","volume":"84","author":"Dichtl","year":"1999","journal-title":"Circ. Res."},{"key":"C9FO00749K-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jjcc.2018.05.010","volume":"73","author":"Moriya","year":"2019","journal-title":"J. Cardiol."},{"key":"C9FO00749K-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"506","DOI":"10.9755\/ejfa.2016-01-086","volume":"28","author":"Harijono","year":"2016","journal-title":"Emir. J. Food Agric."},{"key":"C9FO00749K-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1002\/jsfa.7057","volume":"95","author":"Naidu","year":"2015","journal-title":"J. Sci. Food Agric."},{"key":"C9FO00749K-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.biochi.2018.02.011","volume":"148","author":"Binesh","year":"2018","journal-title":"Biochimie"},{"key":"C9FO00749K-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.lfs.2018.01.012","volume":"196","author":"Binesh","year":"2018","journal-title":"Life Sci."},{"key":"C9FO00749K-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.bbalip.2019.04.010","volume":"1864","author":"Li","year":"2019","journal-title":"Biochim. Biophys. Acta, Mol. Cell Biol. Lipids"},{"key":"C9FO00749K-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.cmet.2008.04.001","volume":"7","author":"Ge","year":"2008","journal-title":"Cell Metab."},{"key":"C9FO00749K-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nrd4280","volume":"13","author":"Cynthia","year":"2014","journal-title":"Nat. Rev. Drug Discovery"},{"key":"C9FO00749K-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4674","DOI":"10.1016\/j.bmc.2007.04.031","volume":"15","author":"Jain","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"C9FO00749K-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s12013-015-0525-8","volume":"72","author":"Hao","year":"2015","journal-title":"Cell Biochem. Biophys."},{"key":"C9FO00749K-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3945\/jn.110.125591","volume":"141","author":"Uemura","year":"2011","journal-title":"J. Nutr."},{"key":"C9FO00749K-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.atherosclerosis.2015.02.044","volume":"240","author":"Lv","year":"2015","journal-title":"Atherosclerosis"},{"key":"C9FO00749K-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3923\/pjbs.2011.425.432","volume":"14","author":"Al-Matubsi","year":"2011","journal-title":"Pak. J. Biol. Sci."},{"key":"C9FO00749K-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.vph.2014.10.003","volume":"63","author":"Rostama","year":"2014","journal-title":"Vasc. Pharmacol."},{"key":"C9FO00749K-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.atherosclerosis.2012.04.010","volume":"225","author":"Liu","year":"2012","journal-title":"Atherosclerosis"},{"key":"C9FO00749K-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1161\/CIRCULATIONAHA.106.675462","volume":"115","author":"Erik","year":"2007","journal-title":"Circulation"},{"key":"C9FO00749K-(cit57)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1161\/ATVBAHA.111.225144","volume":"31","author":"Wu","year":"2011","journal-title":"Arterioscler., Thromb., Vasc. Biol."},{"key":"C9FO00749K-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MOL.0000000000000337","volume":"27","author":"Briot","year":"2016","journal-title":"Curr. Opin. Lipidol."},{"key":"C9FO00749K-(cit59)\/*[position()=1]","first-page":"73","volume":"38","author":"He","year":"2018","journal-title":"Biosci. Rep."},{"key":"C9FO00749K-(cit60)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1046\/j.1462-5822.2003.00263.x","volume":"5","author":"Schorey","year":"2010","journal-title":"Cell. Microbiol."},{"key":"C9FO00749K-(cit61)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.intimp.2004.06.012","volume":"4","author":"Yoon","year":"2004","journal-title":"Int. Immunopharmacol."},{"key":"C9FO00749K-(cit62)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.intimp.2010.06.004","volume":"10","author":"Jung","year":"2010","journal-title":"Int. Immunopharmacol."},{"key":"C9FO00749K-(cit63)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/mnfr.200900208","volume":"54","author":"Hirai","year":"2010","journal-title":"Mol. Nutr. Food Res."},{"key":"C9FO00749K-(cit64)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/cvr\/cvy007","volume":"114","author":"Grootaert","year":"2018","journal-title":"Cardiovasc. Res."},{"key":"C9FO00749K-(cit65)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1161\/CIRCRESAHA.115.306361","volume":"118","author":"Bennett","year":"2016","journal-title":"Circ. Res."},{"key":"C9FO00749K-(cit66)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1038\/nm.2538","volume":"17","author":"Weber","year":"2011","journal-title":"Nat. Med."},{"key":"C9FO00749K-(cit67)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1124\/jpet.110.172684","volume":"336","author":"Esfandiarei","year":"2011","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"C9FO00749K-(cit68)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.vph.2010.09.007","volume":"53","author":"Choi","year":"2010","journal-title":"Vasc. Pharmacol."},{"key":"C9FO00749K-(cit69)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1161\/01.ATV.0000133194.94939.42","volume":"24","author":"Abedin","year":"2004","journal-title":"Arterioscler., Thromb., Vasc. Biol."},{"key":"C9FO00749K-(cit70)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.biochi.2014.03.011","volume":"102","author":"Manivannan","year":"2014","journal-title":"Biochimie"},{"key":"C9FO00749K-(cit71)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1161\/CIRCRESAHA.114.302721","volume":"114","author":"Bentzon","year":"2014","journal-title":"Circ. Res."},{"key":"C9FO00749K-(cit72)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/rth2.12088","volume":"2","author":"Howes","year":"2018","journal-title":"Res. Pract. Thromb. Haemostasis"},{"key":"C9FO00749K-(cit73)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1038\/aps.2016.52","volume":"37","author":"Su","year":"2016","journal-title":"Acta Pharmacol. Sin."},{"key":"C9FO00749K-(cit74)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10846","DOI":"10.1038\/srep10846","volume":"5","author":"Chen","year":"2015","journal-title":"Sci. Rep."},{"key":"C9FO00749K-(cit75)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1038\/nm1102-1227","volume":"8","author":"Ruggeri","year":"2002","journal-title":"Nat. Med."},{"key":"C9FO00749K-(cit76)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.phymed.2010.08.015","volume":"18","author":"Gong","year":"2011","journal-title":"Phytomedicine"},{"key":"C9FO00749K-(cit77)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1253\/circj.CJ-09-0818","volume":"74","author":"Alexander","year":"2010","journal-title":"Circ. J."},{"key":"C9FO00749K-(cit78)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.thromres.2011.12.026","volume":"129","author":"Rosanna","year":"2012","journal-title":"Thromb. Res."},{"key":"C9FO00749K-(cit79)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/S1875-5364(13)60070-9","volume":"11","author":"Yang","year":"2013","journal-title":"Chin. J. Nat. Medicines"},{"key":"C9FO00749K-(cit80)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1002\/cjoc.201500276","volume":"33","author":"Tan","year":"2015","journal-title":"Chin. J. Chem."},{"key":"C9FO00749K-(cit81)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1073\/pnas.0608438104","volume":"104","author":"Lopez","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C9FO00749K-(cit82)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.1016\/j.bmcl.2016.05.032","volume":"26","author":"Zheng","year":"2016","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"C9FO00749K-(cit83)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.nano.2017.12.019","volume":"14","author":"Wei","year":"2018","journal-title":"Nanomedicine"},{"key":"C9FO00749K-(cit84)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.thromres.2016.11.021","volume":"150","author":"Rafiq","year":"2017","journal-title":"Thromb. Res."},{"key":"C9FO00749K-(cit85)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1136\/gut.2011.239848","volume":"60","author":"van Soest","year":"2011","journal-title":"Gut"},{"key":"C9FO00749K-(cit86)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41569-019-0169-2","volume":"16","author":"Back","year":"2019","journal-title":"Nat. Rev. Cardiol."},{"key":"C9FO00749K-(cit87)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2009.09.009","volume":"54","author":"Libby","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"C9FO00749K-(cit88)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1161\/01.ATV.0000160549.60980.a8","volume":"25","author":"Kim","year":"2005","journal-title":"Arterioscler., Thromb., Vasc. Biol."},{"key":"C9FO00749K-(cit89)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1126\/science.1061620","volume":"293","author":"Yuan","year":"2001","journal-title":"Science"},{"key":"C9FO00749K-(cit90)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1080\/14786419.2015.1065493","volume":"30","author":"Selim","year":"2016","journal-title":"Nat. Prod. Res."},{"key":"C9FO00749K-(cit91)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ijpharm.2014.06.032","volume":"472","author":"Okawara","year":"2014","journal-title":"Int. J. Pharm."},{"key":"C9FO00749K-(cit92)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"645","DOI":"10.3390\/nu10050645","volume":"10","author":"Sethi","year":"2018","journal-title":"Nutrients"},{"key":"C9FO00749K-(cit93)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.jff.2018.03.015","volume":"44","author":"Wan","year":"2018","journal-title":"J. Funct. Foods"},{"key":"C9FO00749K-(cit94)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1248\/bpb.b12-00467","volume":"36","author":"Okawara","year":"2013","journal-title":"Biol. Pharm. Bull."},{"key":"C9FO00749K-(cit95)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1248\/bpb.b13-00560","volume":"37","author":"Okawara","year":"2014","journal-title":"Biol. Pharm. Bull."},{"key":"C9FO00749K-(cit96)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1208\/s12249-016-0684-y","volume":"18","author":"Liu","year":"2017","journal-title":"AAPS PharmSciTech"},{"key":"C9FO00749K-(cit97)\/*[position()=1]","first-page":"247948","volume":"2013","author":"Wang","year":"2013","journal-title":"J. Evidence-Based Complementary Altern. Med."},{"key":"C9FO00749K-(cit98)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.niox.2011.12.006","volume":"26","author":"Li","year":"2012","journal-title":"Nitric Oxide"},{"key":"C9FO00749K-(cit99)\/*[position()=1]","first-page":"10","volume":"1","author":"Li","year":"2019","journal-title":"Biotechnol. Adv."},{"key":"C9FO00749K-(cit100)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.intimp.2019.04.033","volume":"72","author":"Zhang","year":"2019","journal-title":"Int. Immunopharmacol."},{"key":"C9FO00749K-(cit101)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1021\/acs.jmedchem.6b00975","volume":"60","author":"Nelson","year":"2017","journal-title":"J. Med. Chem."},{"key":"C9FO00749K-(cit102)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1080\/21691401.2017.1423497","volume":"46","author":"Zong","year":"2018","journal-title":"Artif. Cells, Nanomed., Biotechnol."},{"key":"C9FO00749K-(cit103)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ijpharm.2006.07.003","volume":"326","author":"Wu","year":"2006","journal-title":"Int. J. Pharm."},{"key":"C9FO00749K-(cit104)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1124\/dmd.104.000885","volume":"32","author":"Walle","year":"2004","journal-title":"Drug Metab. Dispos."},{"key":"C9FO00749K-(cit105)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.biopha.2016.12.068","volume":"86","author":"Kiasalari","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"C9FO00749K-(cit106)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ejphar.2012.06.038","volume":"691","author":"Pari","year":"2012","journal-title":"Eur. J. Pharmacol."},{"key":"C9FO00749K-(cit107)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.ejphar.2007.07.017","volume":"574","author":"Dias","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"C9FO00749K-(cit108)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ejphar.2004.08.045","volume":"502","author":"Au","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"C9FO00749K-(cit109)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"19337","DOI":"10.1039\/C4RA13188F","volume":"5","author":"Manivannan","year":"2015","journal-title":"RSC Adv."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2019\/FO\/C9FO00749K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:41:26Z","timestamp":1783014086000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/10\/11\/7022-7036\/645591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":109,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11,13]]}},"URL":"https:\/\/doi.org\/10.1039\/c9fo00749k","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Jian-Guo Jiang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-3361-6149","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 11 April 2019; Accepted 22 September 2019;  Accepted Manuscript published 7 October 2019;  Advance Article published 5 November 2019;  Version of Record published 13 November 2019","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}