{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:50:06Z","timestamp":1788893406768,"version":"build-2803163510"},"reference-count":39,"publisher":"Royal Society of Chemistry (RSC)","issue":"7","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"am","delay-in-days":517,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81773959"],"award-info":[{"award-number":["81773959"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81974528"],"award-info":[{"award-number":["81974528"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>\n                    <italic>Balanophora polyandra<\/italic>\n                    Griff. (\n                    <italic>B. polyandra<\/italic>\n                    ) is a folk medicine used as an antipyretic, antidote, haemostatic, dressing and haematic tonic, for the treatment of gonorrhea, syphilis, wounds, and the bleeding of the alimentary tract by the local people in China.\n                  <\/p>","DOI":"10.1039\/c9fo02494h","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T09:23:47Z","timestamp":1591003427000},"page":"6104-6114","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["<i>Balanophora polyandra<\/i>\n                    Griff. prevents dextran sulfate sodium-induced murine experimental colitis\n                    <i>via<\/i>\n                    the regulation of NF-\u03baB and NLRP3 inflammasome"],"prefix":"10.1039","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7803-3206","authenticated-orcid":false,"given":"Chong","family":"Guo","sequence":"first","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumin","family":"He","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"},{"name":"Third-Grade Pharmacological Laboratory on Chinese Medicine Approved by State Administration of Traditional Chinese Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyue","family":"Gai","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayuan","family":"Qu","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6460-7707","authenticated-orcid":false,"given":"Yue","family":"Shi","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxuan","family":"Cai","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongyao","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengfu","family":"Yuan","sequence":"additional","affiliation":[{"name":"College of Medical Science"},{"name":"China Three Gorges University"},{"name":"Yichang"},{"name":"China"},{"name":"Third-Grade Pharmacological Laboratory on Chinese Medicine Approved by State Administration of Traditional Chinese Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"C9FO02494H-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"14099","DOI":"10.3748\/wjg.v20.i39.14099","volume":"20","author":"Wan","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"C9FO02494H-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1002\/cbdv.200690135","volume":"3","author":"Wang","year":"2006","journal-title":"Chem. Biodiversity"},{"key":"C9FO02494H-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.ejphar.2009.06.011","volume":"616","author":"Tao","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"C9FO02494H-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1053\/j.gastro.2017.08.028","volume":"153","author":"Nikolaus","year":"2017","journal-title":"Gastroenterology"},{"key":"C9FO02494H-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1038\/540S97a","volume":"540","author":"Hodson","year":"2016","journal-title":"Nature"},{"key":"C9FO02494H-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6016","DOI":"10.3748\/wjg.v23.i33.6016","volume":"23","author":"Eichele","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"C9FO02494H-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.bbi.2016.07.161","volume":"58","author":"Carlin","year":"2016","journal-title":"Brain, Behav., Immun."},{"key":"C9FO02494H-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.anaerobe.2017.06.002","volume":"47","author":"P.O.C.","year":"2017","journal-title":"Anaerobe"},{"key":"C9FO02494H-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3390\/ijms20010057","volume":"20","author":"Ranson","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"C9FO02494H-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nri3452","volume":"13","author":"Latz","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"C9FO02494H-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"32937","DOI":"10.18632\/oncotarget.16513","volume":"8","author":"Wang","year":"2017","journal-title":"Oncotarget"},{"key":"C9FO02494H-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"761","DOI":"10.4049\/jimmunol.1601416","volume":"199","author":"Li","year":"2017","journal-title":"J. Immunol."},{"key":"C9FO02494H-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nri2725","volume":"10","author":"Tschopp","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"C9FO02494H-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.bcp.2015.02.002","volume":"94","author":"Sun","year":"2015","journal-title":"Biochem. Pharmacol."},{"key":"C9FO02494H-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/ng.285","volume":"41","author":"Villani","year":"2009","journal-title":"Nat. Genet."},{"key":"C9FO02494H-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4738","DOI":"10.1038\/ncomms5738","volume":"5","author":"Huai","year":"2014","journal-title":"Nat. Commun."},{"key":"C9FO02494H-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/ni.3772","volume":"18","author":"Afonina","year":"2017","journal-title":"Nat. Immunol."},{"key":"C9FO02494H-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4179","DOI":"10.1039\/C7FO00375G","volume":"8","author":"Feng","year":"2017","journal-title":"Food Funct."},{"key":"C9FO02494H-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1007\/s10753-014-0079-8","volume":"38","author":"Gao","year":"2015","journal-title":"Inflammation"},{"key":"C9FO02494H-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.molimm.2018.09.004","volume":"104","author":"Gong","year":"2018","journal-title":"Mol. Immunol."},{"key":"C9FO02494H-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.kint.2016.03.035","volume":"90","author":"Ludwig-Portugall","year":"2016","journal-title":"Kidney Int."},{"key":"C9FO02494H-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1177\/0023677217742681","volume":"52","author":"Hoffmann","year":"2018","journal-title":"Lab. Anim."},{"key":"C9FO02494H-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1023\/A:1005630723111","volume":"45","author":"Fitzpatrick","year":"2000","journal-title":"Dig. Dis. Sci."},{"key":"C9FO02494H-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"437","DOI":"10.3389\/fcimb.2017.00437","volume":"7","author":"Hop","year":"2017","journal-title":"Front. Cell. Infect.\nMicrobiol."},{"key":"C9FO02494H-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.3748\/wjg.v23.i7.1180","volume":"23","author":"Zheng","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"C9FO02494H-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.it.2004.03.008","volume":"25","author":"Bonizzi","year":"2004","journal-title":"Trends Immunol."},{"key":"C9FO02494H-(cit27)\/*[position()=1]","first-page":"4295","volume":"43","author":"Xiong","year":"2018","journal-title":"China J. Chin. Mater. Med."},{"key":"C9FO02494H-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.intimp.2019.04.052","volume":"73","author":"Shen","year":"2019","journal-title":"Int. Immunopharmacol."},{"key":"C9FO02494H-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/ni.2065","volume":"12","author":"Oeckinghaus","year":"2011","journal-title":"Nat. Immunol."},{"key":"C9FO02494H-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"31616","DOI":"10.1074\/jbc.M005378200","volume":"275","author":"Bing","year":"2000","journal-title":"J. Biol. Chem."},{"key":"C9FO02494H-(cit31)\/*[position()=1]","first-page":"302","volume":"21","author":"Zhuang","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"C9FO02494H-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00011-019-01246-8","volume":"68","author":"Liu","year":"2019","journal-title":"Inflammation Res."},{"key":"C9FO02494H-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.3390\/ijms20133328","volume":"20","author":"Kelley","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"C9FO02494H-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1097-2765(02)00599-3","volume":"10","author":"Martinon","year":"2002","journal-title":"Mol. Cell"},{"key":"C9FO02494H-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/cmi.2015.95","volume":"13","author":"Jo","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"C9FO02494H-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.cyto.2018.04.032","volume":"110","author":"Molyvdas","year":"2018","journal-title":"Cytokine"},{"key":"C9FO02494H-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"31023","DOI":"10.18632\/oncotarget.16052","volume":"8","author":"Yuan","year":"2017","journal-title":"Oncotarget"},{"key":"C9FO02494H-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/nm.3893","volume":"21","author":"Guo","year":"2015","journal-title":"Nat. Med."},{"key":"C9FO02494H-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1039\/C6FO01561A","volume":"8","author":"Chen","year":"2017","journal-title":"Food Funct."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/FO\/C9FO02494H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:05:03Z","timestamp":1782968703000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/11\/7\/6104-6114\/646039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7,22]]}},"URL":"https:\/\/doi.org\/10.1039\/c9fo02494h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C9FO02494H","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Chong Guo (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-7803-3206","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Yue Shi (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-6460-7707","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 24 October 2019; Accepted 28 May 2020;  Accepted Manuscript published 1 June 2020;  Advance Article published 23 June 2020;  Version of Record published 22 July 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}