{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T16:24:27Z","timestamp":1788020667450,"version":"build-2784847793"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100002674","name":"Russian Academy of Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002674","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Photochem Photobiol Sci"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1039\/c9pp00406h","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T11:44:23Z","timestamp":1589802263000},"page":"920-930","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Fluorescence characteristics of lipofuscin fluorophores from human retinal pigment epithelium"],"prefix":"10.1007","volume":"19","author":[{"given":"Marina A.","family":"Yakovleva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra Sh.","family":"Radchenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana B.","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey A.","family":"Kostyukov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patimat M.","family":"Arbukhanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey A.","family":"Borzenok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir A.","family":"Kuzmin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikhail A.","family":"Ostrovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,27]]},"reference":[{"key":"190707_CR1","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1301\/nr.2003.oct.342-346","volume":"61","author":"G Wolf","year":"2003","unstructured":"G. Wolf, Lipofuscin and macular degeneration, Nutr. Rev., 2003, 61, 342.","journal-title":"Nutr. Rev."},{"key":"190707_CR2","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1001\/archopht.119.3.359","volume":"119","author":"N Lois","year":"2001","unstructured":"N. Lois, G. E. Holder, C. Bunce, F. W. Fitzke and A. C. Bird, Phenotypic subtypes of Stargardt macular dystrophy-fundus flavimaculatus, Arch. Ophthalmol., 2001, 119, 359.","journal-title":"Arch. Ophthalmol."},{"key":"190707_CR3","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1001\/archopht.1997.01100150611006","volume":"115","author":"A Von Ruckmann","year":"1997","unstructured":"A. Von Ruckmann, F. W. Fitzke and A. C. Bird, In vivo fundus autofluorescence in macular dystrophies, Arch. Ophthalmol., 1997, 115, 609.","journal-title":"Arch. Ophthalmol."},{"key":"190707_CR4","doi-asserted-by":"crossref","unstructured":"F. G. Holz, M. Fleckenstein, S. Schmitz-Valckenberg and A. C. Bird, in Atlas of fundus autofluorescence imaging, ed. F. G. Holz, S. Schmitz-Valckenberg, R. F. Spaide and A. C. Bird, Springer, Berlin, 2007, p. 71.","DOI":"10.1007\/978-3-540-71994-6"},{"key":"190707_CR5","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s004170050209","volume":"237","author":"F G Holz","year":"1999","unstructured":"F. G. Holz, C. Bellmann, M. Margaritidis, F. Schutt, T. P. Otto and H. E. Volcker, Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration, Graefe\u2019s Arch. Clin. Exp. Ophthalmol., 1999, 237, 145.","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"190707_CR6","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1194\/jlr.R000687","volume":"51","author":"J R Sparrow","year":"2009","unstructured":"J. R. Sparrow, Y. Wu, C. Y. Kim and J. Zhou, Phospholipid meets all-trans retinal: the making of RPE bisretinoids, J. Lipid Res., 2009, 51, 247.","journal-title":"J. Lipid Res."},{"key":"190707_CR7","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1562\/0031-8655(2004)079<0127:AACOOL>2.0.CO;2","volume":"79","author":"L E Lamb","year":"2004","unstructured":"L. E. Lamb and J. D. Simon, A2E: a component of ocular lipofuscin, Photochem. Photobiol., 2004, 79, 127.","journal-title":"Photochem. Photobiol."},{"key":"190707_CR8","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1021\/ja953480g","volume":"118","author":"N Sakai","year":"1996","unstructured":"N. Sakai, J. Decatur, K. Nakanishi and G. E. Eldred, Ocular age pigment \u201cA2E\u201d: an unprecedented pyridinium bisretinoid, J. Am. Chem. Soc., 1996, 118, 1559.","journal-title":"J. Am. Chem. Soc."},{"key":"190707_CR9","doi-asserted-by":"crossref","unstructured":"J. R. Sparrow, S. R. Kim, A. M. Cuervo and U. Bandhyopadhyayand, A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity, Adv. Exp. Med. Biol., 2008, 613, 393.","DOI":"10.1007\/978-0-387-74904-4_46"},{"key":"190707_CR10","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.exer.2003.10.023","volume":"78","author":"L B Avalle","year":"2004","unstructured":"L. B. Avalle, Z. Wang, J. P. Dillon and E. R. Gaillard, Observation of A2E oxidation products in human retinal lipofuscin, Exp. Eye Res., 2004, 78, 895.","journal-title":"Exp. Eye Res."},{"key":"190707_CR11","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.exer.2004.06.024","volume":"79","author":"J P Dillon","year":"2004","unstructured":"J. P. Dillon, Z. Wang, L. B. Avalle and E. R. Gaillard, The photochemical oxidation of A2E results in the formation of a 5,8,5\u2032,8\u2032, -bis-furanoid oxide, Exp. Eye Res., 2004, 79, 537.","journal-title":"Exp. Eye Res."},{"key":"190707_CR12","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1007\/s00216-014-8353-z","volume":"407","author":"T B Feldman","year":"2015","unstructured":"T. B. Feldman, M. A. Yakovleva, P. M. Arbukhanova, S. A. Borzenok, A. S. Kononikhin, I. A. Popov, E. N. Nikolaev and M. A. Ostrovsky, Changes in spectral properties and composition of lipofuscin fluorophores from human retinal pigment epithelium with age and pathology, Anal. Bioanal. Chem., 2015, 407, 1075.","journal-title":"Anal. Bioanal. Chem."},{"key":"190707_CR13","doi-asserted-by":"crossref","unstructured":"K. D. Yoon, K. Yamamoto, K. Ueda, J. Zhou and J. R. Sparrow, A novel source of methylglyoxal and glyoxal in retina: implications for age related macular degeneration, PLoS One, 2012, 7, e41309.","DOI":"10.1371\/journal.pone.0041309"},{"key":"190707_CR14","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1562\/2006-04-01-RA-864","volume":"82","author":"Z Wang","year":"2006","unstructured":"Z. Wang, L. M. M. Keller, J. Dillon and E. R. Gaillard, Oxidation of A2E results in the formation of highly reactive aldehydes and ketones, Photochem. Photobiol., 2006, 82, 1251.","journal-title":"Photochem. Photobiol."},{"key":"190707_CR15","doi-asserted-by":"publisher","first-page":"7275","DOI":"10.1073\/pnas.0913112107","volume":"107","author":"Y Wu","year":"2010","unstructured":"Y. Wu, E. Yanase, X. Feng, M. M. Siegel and J. R. Sparrow, Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration, Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 7275.","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"190707_CR16","doi-asserted-by":"crossref","unstructured":"S. R. Kim, Y. P. Jang, S. Jockusch, N. E. Fishkin, N. J. Turro and J. R. Sparrow, The all-trans-retinal dimer series of lipo-fuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model, Proc. Natl. Acad. Sci. U. S. A., 2007, 104, 19273.","DOI":"10.1073\/pnas.0708714104"},{"key":"190707_CR17","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1039\/c0pp00207k","volume":"9","author":"J R Sparrow","year":"2010","unstructured":"J. R. Sparrow, Y. Wu, T. Nagasaki, K. D. Yoon, K. Yamamoto and J. Zhou, Fundus autofluorescence and the bisretinoids of retina, Photochem. Photobiol. Sci., 2010, 9, 1480.","journal-title":"Photochem. Photobiol. Sci."},{"key":"190707_CR18","doi-asserted-by":"publisher","first-page":"9084","DOI":"10.1167\/iovs.11-8632","volume":"52","author":"K Yamamoto","year":"2011","unstructured":"K. Yamamoto, K. D. Yoon, K. Ueda, M. Hashimoto and J. R. Sparrow, A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine, Invest. Ophthalmol. Visual Sci., 2011, 52, 9084.","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"190707_CR19","unstructured":"F. C. Delori, C. K. Dorey, G. Staurenghi, O. Arend, D. G. Goger and J. J. Weiter, In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics, Invest. Ophthalmol. Visual Sci., 1995, 36, 718."},{"key":"190707_CR20","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1038\/s41433-018-0109-0","volume":"32","author":"T B Feldman","year":"2018","unstructured":"T. B. Feldman, M. A. Yakovleva, A. V. Larichev, P. M. Arbukhanova, A. Sh. Radchenko, S. A. Borzenok, V. A. Kuzmin and M. A. Ostrovsky, Spectral analysis of fundus autofluorescence pattern as a tool to detect early stages of degeneration in the retina and retinal pigment epithelium, Eye, 2018, 32, 1440.","journal-title":"Eye"},{"key":"190707_CR21","first-page":"2435","volume":"43","author":"A D Marmorstein","year":"2002","unstructured":"A. D. Marmorstein, L. Y. Marmorstein, H. Sakaguchi and J. G. Hollyfield, Spectral profiling of autofluorescence associated with lipofuscin, bruch\u2019s membrane, and sub-RPE deposits in normal and AMD eyes, Invest. Ophthalmol. Visual Sci., 2002, 43, 2435.","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"190707_CR22","doi-asserted-by":"crossref","unstructured":"L. Sauer, R. H. Gensure, K. M. Andersen, L. Kreilkamp, G. S. Hageman, M. Hammer and P. S. Bernstein, Patterns of fundus autofluorescence lifetimes in eyes of individuals with nonexudative agerelated macular degeneration, Invest. Ophthalmol. Visual Sci., 2018, 59, AMD65.","DOI":"10.1167\/iovs.17-23764"},{"key":"190707_CR23","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1007\/s00347-009-1975-4","volume":"106","author":"D Schweitzer","year":"2009","unstructured":"D. Schweitzer, S. Quick, S. Schenke, M. Klemm, S. Gehlert, M. Hammer, S. Jentsch and J. Fischer, Comparison of parameters of time-resolved autofluorescence between healthy subjects and patients suffering from early AMD, Ophthalmology, 2009, 106, 714.","journal-title":"Ophthalmology"},{"key":"190707_CR24","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1167\/tvst.7.3.20","volume":"7","author":"K M Andersen","year":"2018","unstructured":"K. M. Andersen, L. Sauer, R. H. Gensure, M. Hammer and P. S. Bernstein, Characterization of retinitis pigmentosa using fluorescence lifetime imaging ophthalmoscopy (FLIO), Transl. Vision Sci. Technol., 2018, 7, 20.","journal-title":"Transl. Vision Sci. Technol."},{"key":"190707_CR25","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1167\/iovs.17-23336","volume":"59","author":"C Dysli","year":"2018","unstructured":"C. Dysli, K. Sch\u00fcrch, E. Pascal, S. Wolf and M. S. Zinkernagel, Fundus autofluorescence lifetime patterns in retinitis pigmentosa, Invest. Ophthalmol. Visual Sci., 2018, 59, 1769.","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"190707_CR26","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1167\/iovs.15-18033","volume":"57","author":"C Dysli","year":"2016","unstructured":"C. Dysli, S. Wolf, K. Hatz and M. S. Zinkernagel, Fluorescence Lifetime Imaging in Stargardt Disease: Potential Marker for Disease Progression, Invest. Ophthalmol. Visual Sci., 2016, 57, 832.","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"190707_CR27","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.oret.2017.10.008","volume":"2","author":"L Sauer","year":"2018","unstructured":"L. Sauer, R. H. Gensure, M. Hammer and P. S. Bernstein, Fluorescence lifetime imaging ophthalmoscopy: a novel way to assess macular telangiectasia type 2, Ophthalmol. Retina, 2018, 2, 587.","journal-title":"Ophthalmol. Retina"},{"key":"190707_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1117\/1.JBO.23.9.091415","volume":"23","author":"L Sauer","year":"2018","unstructured":"L. Sauer, K. M. Andersen, C. Dysli, M. S. Zinkernagel, P. S. Bernstein and M. Hammer, Review of clinical approaches in fluorescence lifetime imaging ophthal-moscopy, J. Biomed. Opt., 2018, 23, 1.","journal-title":"J. Biomed. Opt."},{"key":"190707_CR29","doi-asserted-by":"publisher","first-page":"61106","DOI":"10.1117\/1.JBO.20.6.061106","volume":"20","author":"D Schweitzer","year":"2015","unstructured":"D. Schweitzer, L. Deutsch, M. Klemm, S. Jentsch, M. Hammer, S. Peters, J. Haueisen, U. A. Muller and J. Dawczynski, Fluorescence lifetime imaging ophthal-moscopy in type 2 diabetic patients who have no signs of diabetic retinopathy, J. Biomed. Opt., 2015, 20, 61106.","journal-title":"J. Biomed. Opt."},{"key":"190707_CR30","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1111\/aos.12609","volume":"93","author":"S Jentsch","year":"2014","unstructured":"S. Jentsch, D. Schweitzer, K. U. Schmidtke, S. Peters, J. Dawczynski, K. J. Bar and M. Hammer, Retinal fluorescence lifetime imaging ophthalmoscopy measures depend on the severity of Alzheimer\u2019s disease. Acta, Ophthalmologica, 2014, 93, 241.","journal-title":"Ophthalmologica"},{"key":"190707_CR31","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1038\/s41433-019-0406-2","volume":"33","author":"S R Sadda","year":"2019","unstructured":"S. R. Sadda, E. Borrelli, W. Fan, A. Ebraheem, K. M. Marion, M. Harrington and S. Kwon, A pilot study of fluorescence lifetime imaging ophthalmoscopy in pre-clinical Alzheimer\u2019s disease, Eye, 2019, 33, 1271.","journal-title":"Eye"},{"key":"190707_CR32","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0076-6879(92)10004-W","volume":"210","author":"J M Beechem","year":"1992","unstructured":"J. M. Beechem, Global analysis of biochemical and biophysical data, Methods Enzymol., 1992, 210, 37.","journal-title":"Methods Enzymol."},{"key":"190707_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1006\/abio.1997.2339","volume":"253","author":"M M Krishna","year":"1997","unstructured":"M. M. Krishna and N. Periasamy, Spectrally constrained global analysis of fluorescence decays in biomembrane systems, Anal. Biochem., 1997, 253, 1.","journal-title":"Anal. Biochem."},{"key":"190707_CR34","doi-asserted-by":"crossref","unstructured":"J. R. Lakowicz, Principles of fluorescence spectroscopy, Springer, New York, 3rd edn, 2006, pp. 97\u2013149.","DOI":"10.1007\/978-0-387-46312-4"},{"key":"190707_CR35","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1007\/s11172-010-0073-8","volume":"59","author":"T B Feldman","year":"2010","unstructured":"T. B. Feldman, M. A. Yakovleva, A. E. Dontsov and M. A. Ostrovsky, Fluorescence emission and excitation spectra of fluorophores of lipofuscin granules isolated from retinal pigment epithelium of human cadaver eyes, Russ. Chem. Bull. Int. Ed., 2010, 59, 276.","journal-title":"Russ. Chem. Bull. Int. Ed."},{"key":"190707_CR36","unstructured":"Russian Federation law N 4180-I dated 22.12.1992: On human organs or tissue transplantation (with modifications and additions). http:\/\/base.garant.ru\/136366\/."},{"key":"190707_CR37","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","volume":"226","author":"J Folch","year":"1957","unstructured":"J. Folch, M. Lees and G. H. S. Stanley, A simple method for the isolation and purification of total lipids from animal tissues, J. Biol. Chem., 1957, 226, 497.","journal-title":"J. Biol. Chem."},{"key":"190707_CR38","doi-asserted-by":"publisher","first-page":"14609","DOI":"10.1073\/pnas.95.25.14609","volume":"95","author":"C A Parish","year":"1998","unstructured":"C. A. Parish, M. Hashimoto, K. Nakanishi, J. Dillon and J. R. Sparrow, Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium, Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 14609.","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"190707_CR39","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1134\/S1607672906040089","volume":"409","author":"M A Yakovleva","year":"2006","unstructured":"M. A. Yakovleva, N. L. Sakina, A. S. Kononikhin, T. B. Feldman, E. N. Nikolaev, A. E. Dontsov and M. A. Ostrovsky, Detection and study of the products of photooxidation of N-Retinylidene-N-retinylethanolamine (A2E), the fluorophore of lipofuscin granules from retinal pigment epithelium of human donor eyes, Dokl. Biochem. Biophys., 2006, 409, 223.","journal-title":"Dokl. Biochem. Biophys."},{"key":"190707_CR40","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1002\/jms.1795","volume":"45","author":"L S Murdaugh","year":"2010","unstructured":"L. S. Murdaugh, L. B. Avalle, S. Mandal, A. E. Dill, J. Dillon, J. D. Simond and E. R. Gaillard, Compositional studies of human RPE lipofuscin, Mass. Spectrom., 2010, 45, 1139.","journal-title":"Mass. Spectrom."},{"key":"190707_CR41","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1039\/c0pp00230e","volume":"9","author":"D B Gutierrez","year":"2010","unstructured":"D. B. Gutierrez, L. Blakeley, P. W. Goletz, K. L. Schey, A. Hanneken, Y. Koutalos and R. K. Crouchand, Z. Ablonczy, Mass spectrometry provides accurate and sensitive quantitation of A2E, Photochem. Photobiol. Sci., 2010, 9, 1513.","journal-title":"Photochem. Photobiol. Sci."},{"key":"190707_CR42","doi-asserted-by":"publisher","first-page":"3366","DOI":"10.1167\/iovs.13-11808","volume":"54","author":"Y Miura","year":"2013","unstructured":"Y. Miura, G. Huettmann, R. Orzekowsky-Schroeder, P. Steven, M. Szasz\u00e1k, N. Koop and R. Brinkmann, Two-photon microscopy and fluorescence lifetime imaging of retinal pigment epithelial cells under oxidative stress, Invest. Ophthalmol. Visual Sci., 2013, 54, 3366.","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"190707_CR43","doi-asserted-by":"crossref","unstructured":"L. Ragauskaite, R. C. Heckathorn and E. R. Gaillard, Environmental effects on the photochemistry of A2E, a component of human retinal lipofuscin, Photochem. Photobiol., 2001, 74, 483.","DOI":"10.1562\/0031-8655(2001)074<0483:EEOTPO>2.0.CO;2"},{"key":"190707_CR44","doi-asserted-by":"crossref","unstructured":"E. R. Gaillard, S. J. Atherton, G. Eldred and J. Dillon, Photophysical studies on human retinal lipofuscin, Photochem. Photobiol., 1995, 61, 448.","DOI":"10.1111\/j.1751-1097.1995.tb02343.x"},{"key":"190707_CR45","doi-asserted-by":"publisher","first-page":"20155","DOI":"10.1074\/jbc.M109.021345","volume":"284","author":"Y Wu","year":"2009","unstructured":"Y. Wu, N. E. Fishkin, A. Pande, J. Pande and J. R. Sparrow, Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease, J. Biol. Chem., 2009, 284, 20155.","journal-title":"J. Biol. Chem."},{"key":"190707_CR46","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/j.1751-1097.1991.tb02013.x","volume":"54","author":"F Docchio","year":"1991","unstructured":"F. Docchio, M. Boulton, R. Cubeddu, R. Ramponi and P. D. Barker, Age-related changes in the fluorescence of melanin and lipofuscin granules of the retinal pigment epithelium: a time-resolved fluorescence spectroscopy study, Photochem. Photobiol., 1991, 54, 247.","journal-title":"Photochem. Photobiol."},{"key":"190707_CR47","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1111\/j.1751-1097.1999.tb07986.x","volume":"70","author":"R Cubeddu","year":"1999","unstructured":"R. Cubeddu, P. Taroni, D. N. Hu, N. Sakai, K. Nakanishi and J. E. Roberts, Photophysical studies of A2-E, putative precursor of lipofuscin, in human retinal pigment epithelial cells, Photochem. Photobiol., 1999, 70, 172.","journal-title":"Photochem. Photobiol."},{"key":"190707_CR48","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1002\/jemt.20427","volume":"70","author":"D Schweitzer","year":"2007","unstructured":"D. Schweitzer, S. Schenke, M. Hammer, F. Schweitzer, S. Jentsch, E. Birckner, W. Becker and A. Bergmann, Towards metabolic mapping of the human retina, Microsc. Res. Tech., 2007, 70, 410.","journal-title":"Res. Tech."},{"key":"190707_CR49","doi-asserted-by":"crossref","first-page":"4857","DOI":"10.1167\/iovs.17-22184","volume":"58","author":"C Dysli","year":"2017","unstructured":"C. Dysli, R. Fink, S. Wolf and M. S. Zinkernagel, Fluorescence Lifetimes of Drusen in Age-Related Macular Degeneration, Invest. Ophthalmol. Visual Sci., 2017, 58, 4857.","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"190707_CR50","doi-asserted-by":"crossref","unstructured":"M. Hammer, S. Quick, M. Klemm, S. Schenke, N. Mata, A. Eitner and D. Schweitzer, In vivo and in vitro investigations of retinal fluorophores in age-related macular degeneration by fluorescence lifetime imaging, Proc. SPIE, 2009, 7183, 71832S.","DOI":"10.1117\/12.807943"},{"key":"190707_CR51","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.preteyeres.2017.06.005","volume":"60","author":"C Dysli","year":"2017","unstructured":"C. Dysli, S. Wolf, M. Y. Berezin, L. Sauer, M. Hammer and M. S. Zinkernagel, Fluorescence lifetime imaging ophthalmoscopy, Prog. Retinal Eye Res., 2017, 60, 120.","journal-title":"Prog. Retinal Eye Res."}],"container-title":["Photochemical &amp; Photobiological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1039\/c9pp00406h.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1039\/c9pp00406h\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/PP\/C9PP00406H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1039\/c9pp00406h.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T23:23:48Z","timestamp":1722900228000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1039\/c9pp00406h"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":51,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["190707"],"URL":"https:\/\/doi.org\/10.1039\/c9pp00406h","relation":{},"ISSN":["1474-905X","1474-9092"],"issn-type":[{"value":"1474-905X","type":"print"},{"value":"1474-9092","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"4 October 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}