{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:39:32Z","timestamp":1790883572820,"version":"4.1.0"},"reference-count":45,"publisher":"Royal Society of Chemistry (RSC)","issue":"23","license":[{"start":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T00:00:00Z","timestamp":1635984000000},"content-version":"am","delay-in-days":673,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2020YFE0201700"],"award-info":[{"award-number":["2020YFE0201700"]}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<p>Liposome membrane fluidity can influence its interaction with pulmonary physiological barriers, including mucus permeation, macrophage uptake and trachea permeation.<\/p>","DOI":"10.1039\/d0bm01529f","type":"journal-article","created":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T09:33:46Z","timestamp":1604482426000},"page":"6786-6797","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Exploring the influence of inhaled liposome membrane fluidity on its interaction with pulmonary physiological barriers"],"prefix":"10.1039","volume":"8","author":[{"given":"Jing","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Pharmacy"},{"name":"Shenyang Pharmaceutical University"},{"name":"Shenyang 110016"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Su","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Shenyang Pharmaceutical University"},{"name":"Shenyang 110016"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Qin","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Shenyang Pharmaceutical University"},{"name":"Shenyang 110016"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Shenyang Pharmaceutical University"},{"name":"Shenyang 110016"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5036-6559","authenticated-orcid":false,"given":"Shirui","family":"Mao","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Shenyang Pharmaceutical University"},{"name":"Shenyang 110016"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"D0BM01529F-(cit1)\/*[position()=1]","volume-title":"Controlled Pulmonary Drug Delivery","author":"O'Donnell","year":"2011","unstructured":"K. P. O'Donnell   and  H. D. C.Smyth , in  Controlled Pulmonary Drug Delivery , ed.  H. D. C. Smyth  and  A. J. Hickey ,  Springer ,  New York ,  2011 , ch. 1, pp.  1\u20134"},{"key":"D0BM01529F-(cit2)\/*[position()=1]","volume-title":"Controlled Pulmonary Drug Delivery","author":"El-Sherbiny","year":"2011","unstructured":"I. M. El-Sherbiny  ,  D. G.Villanueva ,  D.Herrera  and  H. D. C.Smyth , in  Controlled Pulmonary Drug Delivery , ed.  H. D. C. Smyth  and  A. J. Hickey ,  Springer ,  New York ,  2011 , ch. 5, pp.  102\u2013103"},{"key":"D0BM01529F-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.drudis.2019.09.023","volume":"25","author":"Liu","year":"2020","journal-title":"Drug Discovery Today"},{"key":"D0BM01529F-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0168-3659(03)00358-4","volume":"92","author":"Wong","year":"2003","journal-title":"J. Controlled Release"},{"key":"D0BM01529F-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1007\/s11095-016-1911-7","volume":"33","author":"Nahar","year":"2016","journal-title":"Pharm. Res."},{"key":"D0BM01529F-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6074","DOI":"10.1021\/acs.langmuir.6b00741","volume":"32","author":"Takechi-Haraya","year":"2016","journal-title":"Langmuir"},{"key":"D0BM01529F-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1800039","DOI":"10.1002\/ejlt.201800039","volume":"120","author":"Jovanovi\u0107","year":"2018","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"D0BM01529F-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/chir.23171","volume":"32","author":"Hanashima","year":"2020","journal-title":"Chirality"},{"key":"D0BM01529F-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.bpj.2018.08.042","volume":"115","author":"Yano","year":"2018","journal-title":"Biophys. J."},{"key":"D0BM01529F-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jcis.2004.05.042","volume":"278","author":"Liang","year":"2004","journal-title":"J. Colloid Interface Sci."},{"key":"D0BM01529F-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1208\/s12249-016-0624-x","volume":"18","author":"Takechi-Haraya","year":"2017","journal-title":"AAPS PharmSciTech"},{"key":"D0BM01529F-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ijpharm.2010.05.017","volume":"395","author":"Bellavance","year":"2010","journal-title":"Int. J. Pharm."},{"key":"D0BM01529F-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1021\/mp800069c","volume":"6","author":"Kawano","year":"2009","journal-title":"Mol. Pharm."},{"key":"D0BM01529F-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1002\/jps.22001","volume":"99","author":"Orthmann","year":"2010","journal-title":"J. Pharm. Sci."},{"key":"D0BM01529F-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5362","DOI":"10.1073\/pnas.1818924116","volume":"116","author":"Yu","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D0BM01529F-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1021\/acs.molpharmaceut.7b00099","volume":"14","author":"Franz\u00e9","year":"2017","journal-title":"Mol. Pharm."},{"key":"D0BM01529F-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.apsb.2019.02.010","volume":"9","author":"Wu","year":"2019","journal-title":"Acta Pharm. Sin. B"},{"key":"D0BM01529F-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1021\/acs.molpharmaceut.7b00051","volume":"14","author":"Takechi-Haraya","year":"2017","journal-title":"Mol. Pharm."},{"key":"D0BM01529F-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1016\/j.bbamem.2014.01.028","volume":"1838","author":"Lopez-Rodriguez","year":"2014","journal-title":"Biochim. Biophys. Acta, Biomembr."},{"key":"D0BM01529F-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.ijpharm.2018.05.076","volume":"547","author":"Dong","year":"2018","journal-title":"Int. J. Pharm."},{"key":"D0BM01529F-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jconrel.2018.03.011","volume":"277","author":"Conte","year":"2018","journal-title":"J. Controlled Release"},{"key":"D0BM01529F-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.colsurfb.2015.08.027","volume":"135","author":"Angelo","year":"2015","journal-title":"Colloids Surf., B"},{"key":"D0BM01529F-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ejpb.2018.06.006","volume":"130","author":"Pellosi","year":"2018","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D0BM01529F-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ejpb.2019.08.017","volume":"143","author":"Li","year":"2019","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D0BM01529F-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1021\/mp400372j","volume":"11","author":"Kaur","year":"2014","journal-title":"Mol. Pharm."},{"key":"D0BM01529F-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12135","DOI":"10.1021\/jp406340y","volume":"117","author":"Sreekanth","year":"2013","journal-title":"J. Phys. Chem. B"},{"key":"D0BM01529F-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4830","DOI":"10.1021\/la304768f","volume":"29","author":"Suga","year":"2013","journal-title":"Langmuir"},{"key":"D0BM01529F-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1023\/A:1020528716621","volume":"8","author":"Parasassi","year":"1998","journal-title":"J. Fluoresc."},{"key":"D0BM01529F-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1021\/jp068383w","volume":"111","author":"Bhattacharya","year":"2007","journal-title":"J. Phys. Chem. B"},{"key":"D0BM01529F-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0168-3659(00)00240-6","volume":"68","author":"Coderch","year":"2000","journal-title":"J. Controlled Release"},{"key":"D0BM01529F-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jcis.2011.02.048","volume":"358","author":"Silva","year":"2011","journal-title":"J. Colloid Interface Sci."},{"key":"D0BM01529F-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0009-3084(02)00176-7","volume":"122","author":"Epand","year":"2003","journal-title":"Chem. Phys. Lipids"},{"key":"D0BM01529F-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10640","DOI":"10.1021\/acs.langmuir.9b01538","volume":"35","author":"Bui","year":"2019","journal-title":"Langmuir"},{"key":"D0BM01529F-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jconrel.2012.03.022","volume":"164","author":"Florence","year":"2012","journal-title":"J. Controlled Release"},{"key":"D0BM01529F-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1007\/s10409-019-00858-x","volume":"35","author":"Tian","year":"2019","journal-title":"Acta Mech. Sin."},{"key":"D0BM01529F-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1038\/s41467-018-05061-3","volume":"9","author":"Yu","year":"2018","journal-title":"Nat. Commun."},{"key":"D0BM01529F-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/nnano.2010.141","volume":"5","author":"Yang","year":"2010","journal-title":"Nat. Nanotechnol."},{"key":"D0BM01529F-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ejpb.2014.12.001","volume":"89","author":"Patel","year":"2015","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D0BM01529F-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3984","DOI":"10.1039\/b821583a","volume":"5","author":"Banquy","year":"2009","journal-title":"Soft Matter"},{"key":"D0BM01529F-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1021\/acsnano.7b07797","volume":"12","author":"Palomba","year":"2018","journal-title":"ACS Nano"},{"key":"D0BM01529F-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"098101","DOI":"10.1103\/PhysRevLett.107.098101","volume":"107","author":"Yi","year":"2011","journal-title":"Phys. Rev. Lett."},{"key":"D0BM01529F-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1002\/adma.201404788","volume":"27","author":"Sun","year":"2015","journal-title":"Adv. Mater."},{"key":"D0BM01529F-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.addr.2008.11.002","volume":"61","author":"Lai","year":"2009","journal-title":"Adv. Drug Delivery Rev."},{"key":"D0BM01529F-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jconrel.2016.12.013","volume":"257","author":"Stern","year":"2017","journal-title":"J. Controlled Release"},{"key":"D0BM01529F-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ejpb.2019.09.020","volume":"144","author":"Garcia-Mouton","year":"2019","journal-title":"Eur. J. Pharm. Biopharm."}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/BM\/D0BM01529F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:50:23Z","timestamp":1783450223000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/8\/23\/6786-6797\/674069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":45,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2020,11,24]]}},"URL":"https:\/\/doi.org\/10.1039\/d0bm01529f","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/D0BM01529F","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Jing Zhao (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/P-2792-2016","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Shirui Mao (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-5036-6559","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 9 September 2020; Accepted 8 October 2020;  Advance Article published 4 November 2020;  Version of Record published 24 November 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}