{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:17:56Z","timestamp":1782973076947,"version":"3.54.5"},"reference-count":38,"publisher":"Royal Society of Chemistry (RSC)","issue":"23","license":[{"start":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T00:00:00Z","timestamp":1643932800000},"content-version":"am","delay-in-days":399,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21871252"],"award-info":[{"award-number":["21871252"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21801026"],"award-info":[{"award-number":["21801026"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21801024"],"award-info":[{"award-number":["21801024"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Key Research and Development Program of China","award":["2018YFC0807301-3"],"award-info":[{"award-number":["2018YFC0807301-3"]}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Commun."],"abstract":"<p>\n                    Taking benzylidene succinimides as a new class of 3C synthons, a highly diastereo- and enantioselective tandem Mannich reaction\/transamidation has been established by reacting them with cyclic trifluoromethyl\n                    <italic>N<\/italic>\n                    -acyl ketimines.\n                  <\/p>","DOI":"10.1039\/d0cc08131k","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T09:55:17Z","timestamp":1612518917000},"page":"2927-2930","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Benzylidene succinimides as 3C synthons for the asymmetric tandem Mannich reaction\/transamidation of cyclic trifluoromethyl ketimines to obtain F\n                    <sub>3<\/sub>\n                    C-containing polycyclic dihydroquinazolinones"],"prefix":"10.1039","volume":"57","author":[{"given":"Xia-Yan","family":"Zhang","sequence":"first","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"},{"name":"National Engineering Research Center of Chiral Drugs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Hao","family":"Dou","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"},{"name":"National Engineering Research Center of Chiral Drugs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Ya","family":"Lu","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"},{"name":"National Engineering Research Center of Chiral Drugs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4689-0235","authenticated-orcid":false,"given":"Yong","family":"You","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4444-9630","authenticated-orcid":false,"given":"Jian-Qiang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0603-707X","authenticated-orcid":false,"given":"Zhen-Hua","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4850-8981","authenticated-orcid":false,"given":"Wei-Cheng","family":"Yuan","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study"},{"name":"Chengdu University"},{"name":"Chengdu 610106"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D0CC08131K-(cit1a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0960-894X(01)80244-4","volume":"4","author":"Levin","year":"1994","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D0CC08131K-(cit1b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1002\/jps.2600840807","volume":"84","author":"Uzunov","year":"1995","journal-title":"J. Pharm. Sci."},{"key":"D0CC08131K-(cit1c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.1016\/S0960-894X(03)00744-3","volume":"13","author":"Hasegawa","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D0CC08131K-(cit2a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5392","DOI":"10.1021\/acs.orglett.6b02774","volume":"18","author":"Sawant","year":"2016","journal-title":"Org. Lett."},{"key":"D0CC08131K-(cit2b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3210","DOI":"10.1039\/C3GC42400F","volume":"16","author":"Wu","year":"2014","journal-title":"Green Chem."},{"key":"D0CC08131K-(cit2c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1021\/cs400591u","volume":"3","author":"Huang","year":"2013","journal-title":"ACS Catal."},{"key":"D0CC08131K-(cit2d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1021\/acs.orglett.5b01654","volume":"17","author":"Saito","year":"2015","journal-title":"Org. Lett."},{"key":"D0CC08131K-(cit2e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"14258","DOI":"10.1021\/acsomega.8b02298","volume":"3","author":"Sawant","year":"2018","journal-title":"ACS Omega"},{"key":"D0CC08131K-(cit2f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12292","DOI":"10.1021\/acscatal.0c02578","volume":"10","author":"Laconsay","year":"2020","journal-title":"ACS Catal."},{"key":"D0CC08131K-(cit3a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1021\/jo0263162","volume":"68","author":"Magnus","year":"2003","journal-title":"J. Org. Chem."},{"key":"D0CC08131K-(cit3b)\/*[position()=1]","first-page":"119","volume":"1","author":"Corbett","year":"2002","journal-title":"Curr. Med. Chem.: Anti-Infect. Agents"},{"key":"D0CC08131K-(cit4a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1021\/cr100166a","volume":"111","author":"Nie","year":"2011","journal-title":"Chem. Rev."},{"key":"D0CC08131K-(cit4b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1021\/cr500368h","volume":"115","author":"Alonso","year":"2015","journal-title":"Chem. Rev."},{"key":"D0CC08131K-(cit4c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1021\/acs.chemrev.5b00392","volume":"116","author":"Zhou","year":"2016","journal-title":"Chem. Rev."},{"key":"D0CC08131K-(cit4d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3887","DOI":"10.1021\/acs.chemrev.7b00778","volume":"118","author":"Zhu","year":"2018","journal-title":"Chem. Rev."},{"key":"D0CC08131K-(cit5a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1039\/C2CC38097H","volume":"49","author":"Xie","year":"2013","journal-title":"Chem. Commun."},{"key":"D0CC08131K-(cit5b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.1002\/adsc.201300534","volume":"355","author":"Zhang","year":"2013","journal-title":"Adv. Synth. Catal."},{"key":"D0CC08131K-(cit5c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.1002\/anie.201210361","volume":"52","author":"Yuan","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CC08131K-(cit5d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15856","DOI":"10.1002\/chem.201303307","volume":"19","author":"Yuan","year":"2013","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CC08131K-(cit5e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5554","DOI":"10.1021\/acs.orglett.5b02668","volume":"17","author":"Zhou","year":"2015","journal-title":"Org. Lett."},{"key":"D0CC08131K-(cit5f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6193","DOI":"10.1039\/C6OB00890A","volume":"14","author":"Zhou","year":"2016","journal-title":"Org. Biomol. Chem."},{"key":"D0CC08131K-(cit5g)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13068","DOI":"10.1002\/chem.201603105","volume":"22","author":"Zhou","year":"2016","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CC08131K-(cit5h)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12697","DOI":"10.1002\/anie.201706304","volume":"56","author":"Dai","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CC08131K-(cit5i)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3372","DOI":"10.1039\/C8OB00707A","volume":"16","author":"Luo","year":"2018","journal-title":"Org. Biomol. Chem."},{"key":"D0CC08131K-(cit5j)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jfluchem.2018.01.008","volume":"208","author":"Zhang","year":"2018","journal-title":"J. Fluorine Chem."},{"key":"D0CC08131K-(cit6a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4566","DOI":"10.1021\/ol502123z","volume":"16","author":"Zhao","year":"2014","journal-title":"Org. Lett."},{"key":"D0CC08131K-(cit6b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11342","DOI":"10.1039\/C7CC06562K","volume":"53","author":"Liu","year":"2017","journal-title":"Chem. Commun."},{"key":"D0CC08131K-(cit6c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"131116","DOI":"10.1016\/j.tet.2020.131116","volume":"76","author":"Zhang","year":"2020","journal-title":"Tetrahedron"},{"key":"D0CC08131K-(cit7a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12534","DOI":"10.1002\/chem.201002183","volume":"16","author":"Wang","year":"2010","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CC08131K-(cit7b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6337","DOI":"10.1039\/C6OB00711B","volume":"14","author":"Zhao","year":"2016","journal-title":"Org. Biomol. Chem."},{"key":"D0CC08131K-(cit7c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13449","DOI":"10.1039\/D0CC05474G","volume":"56","author":"Zhang","year":"2020","journal-title":"Chem. Commun."},{"key":"D0CC08131K-(cit8a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9212","DOI":"10.1039\/C5CC02362A","volume":"51","author":"Yang","year":"2015","journal-title":"Chem. Commun."},{"key":"D0CC08131K-(cit8b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1021\/acs.orglett.9b00734","volume":"21","author":"Gan","year":"2019","journal-title":"Org. Lett."},{"key":"D0CC08131K-(cit8c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1002\/anie.201209126","volume":"52","author":"Liu","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CC08131K-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6162","DOI":"10.1039\/C6CC00705H","volume":"52","author":"Zhao","year":"2016","journal-title":"Chem. Commun."},{"key":"D0CC08131K-(cit10a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9148","DOI":"10.1021\/ja953505b","volume":"118","author":"Radkiewicz","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"D0CC08131K-(cit10b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1021\/jo962214y","volume":"62","author":"Jensen","year":"1997","journal-title":"J. Org. Chem."},{"key":"D0CC08131K-(cit10c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6760","DOI":"10.1021\/acs.orglett.0c02228","volume":"22","author":"Chowdhury","year":"2020","journal-title":"Org. Lett."}],"container-title":["Chemical Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/CC\/D0CC08131K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:55:26Z","timestamp":1782968126000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cc\/article\/57\/23\/2927-2930\/677303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":38,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2021,3,18]]}},"URL":"https:\/\/doi.org\/10.1039\/d0cc08131k","relation":{},"ISSN":["1359-7345","1364-548X"],"issn-type":[{"value":"1359-7345","type":"print"},{"value":"1364-548X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/D0CC08131K","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Crystal Structure Data","URL":"http:\/\/xlink.rsc.org?ccdc=true&msid=D0CC08131K","name":"related_data"},{"value":"Yong You (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-4689-0235","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Jian-Qiang Zhao (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-4444-9630","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Zhen-Hua Wang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-0603-707X","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Wei-Cheng Yuan (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-4850-8981","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Authors can choose between single-blind and double-blind peer review","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 15 December 2020; Accepted 4 February 2021;  Accepted Manuscript published 4 February 2021;  Advance Article published 23 February 2021;  Version of Record published 18 March 2021","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}