{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:35:56Z","timestamp":1791974156453,"version":"4.4.0"},"reference-count":56,"publisher":"Royal Society of Chemistry (RSC)","issue":"9","license":[{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"vor","delay-in-days":81,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100000770","name":"University of Manchester","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000770","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"crossref","award":["891623-SmART"],"award-info":[{"award-number":["891623-SmART"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"crossref","award":["EP\/S023755\/1"],"award-info":[{"award-number":["EP\/S023755\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Soc. Rev."],"abstract":"<p>Ketyl radicals are valuable reactive intermediates for synthesis. This review highlights exciting recent developments in the chemistry of ketyl radicals by comparing contemporary and more classical approaches for their generation and use.<\/p>","DOI":"10.1039\/d0cs00358a","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T06:16:33Z","timestamp":1616480193000},"page":"5349-5365","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":206,"title":["Recent advances in the chemistry of ketyl radicals"],"prefix":"10.1039","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2146-0607","authenticated-orcid":false,"given":"\u00c1ron","family":"P\u00e9ter","sequence":"first","affiliation":[{"name":"Department of Chemistry"},{"name":"The University of Manchester"},{"name":"Manchester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumitra","family":"Agasti","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"The University of Manchester"},{"name":"Manchester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0759-2702","authenticated-orcid":false,"given":"Oliver","family":"Knowles","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"The University of Manchester"},{"name":"Manchester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Pye","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"The University of Manchester"},{"name":"Manchester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3179-2509","authenticated-orcid":false,"given":"David J.","family":"Procter","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"The University of Manchester"},{"name":"Manchester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D0CS00358A-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"18849","DOI":"10.1002\/anie.201910336","volume":"58","author":"Kratish","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9751","DOI":"10.1021\/jacs.8b06089","volume":"140","author":"Nocera","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1021\/jo001781p","volume":"66","author":"Yamamoto","year":"2001","journal-title":"J. Org. Chem."},{"key":"D0CS00358A-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1021\/ja9537538","volume":"118","author":"F\u00fcrstner","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1002\/chem.201405852","volume":"21","author":"Bichovski","year":"2015","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CS00358A-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6186","DOI":"10.1039\/c3ob41263f","volume":"11","author":"Hong","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"D0CS00358A-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4448","DOI":"10.1021\/acs.orglett.6b02184","volume":"18","author":"Tang","year":"2016","journal-title":"Org. Lett."},{"key":"D0CS00358A-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8714","DOI":"10.1002\/anie.201902005","volume":"58","author":"Sandoval","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1080\/15583724.2015.1116094","volume":"56","author":"Dolci","year":"2016","journal-title":"Polym. Rev."},{"key":"D0CS00358A-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2533\/chimia.2020.18","volume":"74","author":"P\u00e9ter","year":"2020","journal-title":"CHIMIA"},{"key":"D0CS00358A-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1021\/acs.accounts.5b00083","volume":"48","author":"Just-Baringo","year":"2015","journal-title":"Acc. Chem. Res."},{"key":"D0CS00358A-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5144","DOI":"10.1021\/acs.orglett.5b02732","volume":"17","author":"Shi","year":"2015","journal-title":"Org. Lett."},{"key":"D0CS00358A-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1002\/adsc.201300073","volume":"355","author":"Yeh","year":"2013","journal-title":"Adv. Synth. Catal."},{"key":"D0CS00358A-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8661","DOI":"10.1002\/anie.201204469","volume":"51","author":"Streuff","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3664","DOI":"10.1039\/C7SC05225A","volume":"9","author":"Cao","year":"2018","journal-title":"Chem. Sci."},{"key":"D0CS00358A-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1016\/S0040-4039(97)00263-3","volume":"38","author":"Corey","year":"1997","journal-title":"Tetrahedron Lett."},{"key":"D0CS00358A-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41929-018-0219-x","volume":"2","author":"Huang","year":"2019","journal-title":"Nat. Catal."},{"key":"D0CS00358A-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12751","DOI":"10.1021\/ja3047975","volume":"134","author":"Parmar","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1038\/nchem.2841","volume":"9","author":"Kern","year":"2017","journal-title":"Nat. Chem."},{"key":"D0CS00358A-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3854","DOI":"10.1021\/jacs.9b00880","volume":"141","author":"Ishii","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9683","DOI":"10.1021\/acs.chemrev.5b00760","volume":"116","author":"K\u00e4rk\u00e4s","year":"2016","journal-title":"Chem. Rev."},{"key":"D0CS00358A-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5322","DOI":"10.1021\/cr300503r","volume":"113","author":"Prier","year":"2013","journal-title":"Chem. Rev."},{"key":"D0CS00358A-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9850","DOI":"10.1021\/acs.chemrev.5b00662","volume":"116","author":"Ravelli","year":"2016","journal-title":"Chem. Rev."},{"key":"D0CS00358A-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10075","DOI":"10.1021\/acs.chemrev.6b00057","volume":"116","author":"Romero","year":"2016","journal-title":"Chem. Rev."},{"key":"D0CS00358A-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10035","DOI":"10.1021\/acs.chemrev.6b00018","volume":"116","author":"Skubi","year":"2016","journal-title":"Chem. Rev."},{"key":"D0CS00358A-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"0052","DOI":"10.1038\/s41570-017-0052","volume":"1","author":"Twilton","year":"2017","journal-title":"Nat. Chem. Rev."},{"key":"D0CS00358A-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0040-4039(01)94515-0","volume":"19","author":"Hedstrand","year":"1978","journal-title":"Tetrahedron Lett."},{"key":"D0CS00358A-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5426","DOI":"10.1039\/C5SC02185E","volume":"6","author":"Cismesia","year":"2015","journal-title":"Chem. Sci."},{"key":"D0CS00358A-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10022","DOI":"10.1021\/ja404342j","volume":"135","author":"Tarantino","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17735","DOI":"10.1021\/ja4100595","volume":"135","author":"Rono","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1021\/jacs.9b13975","volume":"142","author":"Wang","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"18323","DOI":"10.1021\/ja410478a","volume":"135","author":"Petronijevi\u0107","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1126\/science.1251511","volume":"344","author":"Du","year":"2014","journal-title":"Science"},{"key":"D0CS00358A-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8828","DOI":"10.1002\/anie.201501556","volume":"54","author":"Nakajima","year":"2015","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13312","DOI":"10.1002\/anie.201607813","volume":"55","author":"Qi","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5003","DOI":"10.1021\/jacs.7b01373","volume":"139","author":"Lee","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/s41467-017-02698-4","volume":"9","author":"Ye","year":"2018","journal-title":"Nat. Commun."},{"key":"D0CS00358A-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9269","DOI":"10.1002\/chem.201801886","volume":"24","author":"Xia","year":"2018","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CS00358A-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1126\/science.aau1777","volume":"362","author":"Wang","year":"2018","journal-title":"Science"},{"key":"D0CS00358A-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5454","DOI":"10.1002\/anie.201802316","volume":"57","author":"Huang","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8094","DOI":"10.1039\/C8SC02948B","volume":"9","author":"Liu","year":"2018","journal-title":"Chem. Sci."},{"key":"D0CS00358A-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7230","DOI":"10.1039\/C8SC02038H","volume":"9","author":"Berger","year":"2018","journal-title":"Chem. Sci."},{"key":"D0CS00358A-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/nchem.2031","volume":"6","author":"Studer","year":"2014","journal-title":"Nat. Chem."},{"key":"D0CS00358A-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1002\/anie.201710397","volume":"57","author":"Tang","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6888","DOI":"10.1039\/C7SC02175E","volume":"8","author":"Tang","year":"2017","journal-title":"Chem. Sci."},{"key":"D0CS00358A-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1021\/jacs.9b12343","volume":"142","author":"L\u00fcbbesmeyer","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1021\/acscatal.9b04411","volume":"10","author":"Wang","year":"2020","journal-title":"ACS Catal."},{"key":"D0CS00358A-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"20979","DOI":"10.1021\/jacs.0c11214","volume":"142","author":"Hu","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5959","DOI":"10.1021\/cr400685r","volume":"114","author":"Szostak","year":"2014","journal-title":"Chem. Rev."},{"key":"D0CS00358A-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3298","DOI":"10.1021\/jacs.6b00567","volume":"138","author":"Cai","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1002\/chem.201503831","volume":"22","author":"Pan","year":"2016","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CS00358A-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6718","DOI":"10.1002\/chem.201300968","volume":"19","author":"Fazakerley","year":"2013","journal-title":"Chem. \u2013 Eur. J."},{"key":"D0CS00358A-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1021\/jacs.7b13260","volume":"140","author":"Farney","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"D0CS00358A-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1002\/anie.201712369","volume":"57","author":"Leung","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D0CS00358A-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12183","DOI":"10.1038\/ncomms12183","volume":"7","author":"Gong","year":"2016","journal-title":"Nat. Commun."},{"key":"D0CS00358A-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1039\/C0OB00850H","volume":"9","author":"Honda","year":"2011","journal-title":"Org. Biomol. Chem."}],"container-title":["Chemical Society Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/CS\/D0CS00358A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:53:06Z","timestamp":1782967986000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cs\/article\/50\/9\/5349-5365\/681936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":56,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,5,11]]}},"URL":"https:\/\/doi.org\/10.1039\/d0cs00358a","relation":{},"ISSN":["0306-0012","1460-4744"],"issn-type":[{"value":"0306-0012","type":"print"},{"value":"1460-4744","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"\u00c1ron P\u00e9ter (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-2146-0607","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Oliver Knowles (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-0759-2702","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"David J. Procter (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-3179-2509","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 13 April 2020;  Advance Article published 23 March 2021;  Version of Record published 11 May 2021","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}