{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:43:16Z","timestamp":1792150996428,"version":"4.4.0"},"reference-count":31,"publisher":"Royal Society of Chemistry (RSC)","issue":"5","license":[{"start":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T00:00:00Z","timestamp":1620259200000},"content-version":"am","delay-in-days":491,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"crossref","award":["2018YFD0700100"],"award-info":[{"award-number":["2018YFD0700100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31701538"],"award-info":[{"award-number":["31701538"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"crossref","award":["C2019406071"],"award-info":[{"award-number":["C2019406071"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100013058","name":"Jiangsu Provincial Key Research and Development Program","doi-asserted-by":"crossref","award":["BE2018368"],"award-info":[{"award-number":["BE2018368"]}],"id":[{"id":"10.13039\/501100013058","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>In order to avoid the discomfort of digesting milk protein and make full use of the gastrointestinal digestive function, a milk macromolecular peptide was prepared with ACE inhibitory activity after gastrointestinal digestion as the index.<\/p>","DOI":"10.1039\/d0fo00151a","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T08:53:51Z","timestamp":1588755231000},"page":"4403-4415","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The milk macromolecular peptide: preparation and evaluation of antihypertensive activity in rats"],"prefix":"10.1039","volume":"11","author":[{"given":"Pengfei","family":"Cui","sequence":"first","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4784-9899","authenticated-orcid":false,"given":"Xue","family":"Yang","sequence":"additional","affiliation":[{"name":"Basic Medical College"},{"name":"Chengde Medical University"},{"name":"Chengde 067000"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunliang","family":"Li","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiufang","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yucheng","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Owusu","sequence":"additional","affiliation":[{"name":"Koforidua Polytech"},{"name":"Sch Appl Sci & Technol"},{"name":"Dept Hospitality"},{"name":"Koforidua"},{"name":"Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanfen","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9564-0630","authenticated-orcid":false,"given":"Haile","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering"},{"name":"and Institute of Food Physical Processing"},{"name":"Jiangsu University"},{"name":"Zhenjiang 212013"},{"name":"PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"D0FO00151A-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0958-6946(02)00125-5","volume":"12","author":"Leclerc","year":"2002","journal-title":"Int. Dairy J."},{"key":"D0FO00151A-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s10989-009-9196-x","volume":"16","author":"Srinivas","year":"2010","journal-title":"Int. J. Pept. Res. Ther."},{"key":"D0FO00151A-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.idairyj.2006.06.004","volume":"16","author":"L\u00f3pez-Fandi\u00f1o","year":"2006","journal-title":"Int. Dairy J."},{"key":"D0FO00151A-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00217-007-0689-6","volume":"227","author":"Haque","year":"2008","journal-title":"Eur. Food Res. Technol."},{"key":"D0FO00151A-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1021\/jm950590p","volume":"39","author":"Coric","year":"1996","journal-title":"J. Med. Chem."},{"key":"D0FO00151A-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.foodchem.2016.12.039","volume":"224","author":"Rudolph","year":"2017","journal-title":"Food Chem."},{"key":"D0FO00151A-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.foodchem.2016.09.183","volume":"220","author":"Toopcham","year":"2017","journal-title":"Food Chem."},{"key":"D0FO00151A-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.foodchem.2013.01.021","volume":"139","author":"Fern\u00e1ndez","year":"2013","journal-title":"Food Chem."},{"key":"D0FO00151A-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1007\/s10068-013-0248-9","volume":"22","author":"Dadzie","year":"2013","journal-title":"Food Sci. Biotechnol."},{"key":"D0FO00151A-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ultsonch.2014.12.013","volume":"24","author":"Jin","year":"2015","journal-title":"Ultrason. Sonochem."},{"key":"D0FO00151A-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ultsonch.2014.10.020","volume":"23","author":"Ma","year":"2015","journal-title":"Ultrason. Sonochem."},{"key":"D0FO00151A-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s13197-011-0503-0","volume":"51","author":"Xu","year":"2014","journal-title":"J. Food Sci. Technol."},{"key":"D0FO00151A-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.foodchem.2015.06.087","volume":"192","author":"Ketnawa","year":"2016","journal-title":"Food Chem."},{"key":"D0FO00151A-(cit14)\/*[position()=1]","first-page":"43","volume":"38","author":"Chen","year":"2013","journal-title":"J. Cent. South Univ."},{"key":"D0FO00151A-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.procbio.2015.01.017","volume":"50","author":"Li","year":"2015","journal-title":"Process Biochem."},{"key":"D0FO00151A-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/0006-2952(71)90292-9","volume":"20","author":"Cushman","year":"1971","journal-title":"Biochem. Pharmacol."},{"key":"D0FO00151A-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1016\/0024-3205(85)90381-9","volume":"36","author":"Arthur","year":"1985","journal-title":"Life Sci."},{"key":"D0FO00151A-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jff.2014.12.028","volume":"13","author":"Majumder","year":"2015","journal-title":"J. Funct. Foods"},{"key":"D0FO00151A-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00217-004-1004-4","volume":"219","author":"Pripp","year":"2004","journal-title":"Eur. Food Res. Technol."},{"key":"D0FO00151A-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1111\/j.1365-2621.1985.tb10580.x","volume":"50","author":"Mayda","year":"2010","journal-title":"J. Food Sci."},{"key":"D0FO00151A-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1093\/oxfordjournals.jbchem.a121959","volume":"101","author":"Sakai","year":"2008","journal-title":"J. Biochem."},{"key":"D0FO00151A-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jpba.2015.08.035","volume":"117","author":"Jones","year":"2016","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D0FO00151A-(cit23)\/*[position()=1]","first-page":"2707","volume":"49","author":"Sasaki","year":"1985","journal-title":"J. Agric. Chem. Soc. Jpn."},{"key":"D0FO00151A-(cit24)\/*[position()=1]","first-page":"119","volume":"41","author":"Ma","year":"2010","journal-title":"Trans. Chin. Soc. Agric. Mach."},{"key":"D0FO00151A-(cit25)\/*[position()=1]","first-page":"198","volume":"41","author":"Wang","year":"2010","journal-title":"Trans. Chin. Soc. Agric. Mach."},{"key":"D0FO00151A-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/218929a0","volume":"218","author":"Drenth","year":"1968","journal-title":"Nature"},{"key":"D0FO00151A-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/0006-291X(67)90299-9","volume":"29","author":"Schechter","year":"1967","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D0FO00151A-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.1016\/j.foodchem.2013.06.089","volume":"141","author":"Yamada","year":"2013","journal-title":"Food Chem."},{"key":"D0FO00151A-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ejphar.2010.01.017","volume":"632","author":"Miguel-Carrasco","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"D0FO00151A-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1172\/JCI25074","volume":"116","author":"Gough","year":"2006","journal-title":"J. Clin. Invest."},{"key":"D0FO00151A-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.burns.2012.10.008","volume":"39","author":"Demiralay","year":"2013","journal-title":"Burns"}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/FO\/D0FO00151A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:47:33Z","timestamp":1782928053000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/11\/5\/4403-4415\/686625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5,26]]}},"URL":"https:\/\/doi.org\/10.1039\/d0fo00151a","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Xue Yang (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-4784-9899","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Xue Yang (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/V-5706-2018","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Haile Ma (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-9564-0630","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 16 January 2020; Accepted 19 April 2020;  Advance Article published 6 May 2020;  Version of Record published 26 May 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}