{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:47:18Z","timestamp":1784069238977,"version":"3.55.0"},"reference-count":40,"publisher":"Royal Society of Chemistry (RSC)","issue":"12","license":[{"start":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T00:00:00Z","timestamp":1634774400000},"content-version":"am","delay-in-days":659,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32060212"],"award-info":[{"award-number":["32060212"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81760648"],"award-info":[{"award-number":["81760648"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>A novel rice-derived peptide named RDP2 with significant anti-gout potency.<\/p>","DOI":"10.1039\/d0fo01774d","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T07:22:48Z","timestamp":1603264968000},"page":"10542-10553","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Discovery of a novel rice-derived peptide with significant anti-gout potency"],"prefix":"10.1039","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3253-3832","authenticated-orcid":false,"given":"Naixin","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buliang","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zeng","sequence":"additional","affiliation":[{"name":"Public Technical Service Center"},{"name":"Kunming Institute of Zoology"},{"name":"Chinese Academy of Sciences"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saige","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longjun","family":"Shu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemistry in Ethnic Medicine Resource"},{"name":"State Ethnic Affairs Commission & Ministry of Education"},{"name":"School of Ethno-Medicine and Ethno-Pharmacy"},{"name":"Yunnan Minzu University"},{"name":"Kunming"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meifeng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemistry in Ethnic Medicine Resource"},{"name":"State Ethnic Affairs Commission & Ministry of Education"},{"name":"School of Ethno-Medicine and Ethno-Pharmacy"},{"name":"Yunnan Minzu University"},{"name":"Kunming"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3210-8908","authenticated-orcid":false,"given":"Xinwang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology & Embryology"},{"name":"Faculty of Basic Medical Science"},{"name":"Kunming Medical University"},{"name":"Kunming"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"D0FO01774D-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0140-6736(10)60665-4","volume":"377","author":"Burns","year":"2011","journal-title":"Lancet"},{"issue":"1","key":"D0FO01774D-(cit2)\/*[position()=1]","first-page":"27","volume":"58","author":"Pascart","year":"2019","journal-title":"Rheumatology"},{"key":"D0FO01774D-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s13075-018-1600-5","volume":"20","author":"Zhang","year":"2018","journal-title":"Arthritis Res. Ther."},{"key":"D0FO01774D-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.foodchem.2018.08.057","volume":"272","author":"He","year":"2019","journal-title":"Food Chem."},{"key":"D0FO01774D-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3389\/fphar.2020.00049","volume":"11","author":"Li","year":"2020","journal-title":"Front. Pharmacol."},{"key":"D0FO01774D-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S2213-8587(18)30073-1","volume":"6","author":"Khanna","year":"2018","journal-title":"Lancet Diabetes Endocrinol."},{"key":"D0FO01774D-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"163","DOI":"10.5414\/CP202629","volume":"55","author":"Zhou","year":"2017","journal-title":"Int. J. Clin. Pharmacol. Ther."},{"key":"D0FO01774D-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"106298","DOI":"10.1016\/j.leukres.2020.106298","volume":"89","author":"Martens","year":"2020","journal-title":"Leuk. Res."},{"key":"D0FO01774D-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3389\/fped.2019.00517","volume":"7","author":"Bensman","year":"2019","journal-title":"Front. Pediatr."},{"key":"D0FO01774D-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.3389\/fphar.2019.01464","volume":"10","author":"Bao","year":"2019","journal-title":"Front. Pharmacol."},{"key":"D0FO01774D-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1021\/jf405504u","volume":"62","author":"Murota","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"D0FO01774D-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1039\/C7FO01174A","volume":"9","author":"Li","year":"2018","journal-title":"Food Funct."},{"key":"D0FO01774D-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/1753-0407.12208","volume":"7","author":"Paul","year":"2015","journal-title":"J. Diabetes"},{"key":"D0FO01774D-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"A349","DOI":"10.1016\/j.jval.2014.08.722","volume":"17","author":"Malhan","year":"2014","journal-title":"Value Health"},{"key":"D0FO01774D-(cit15)\/*[position()=1]","first-page":"107","volume":"144","author":"Higuchi","year":"2006","journal-title":"Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol."},{"key":"D0FO01774D-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1021\/acs.jafc.8b05879","volume":"67","author":"Liu","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"D0FO01774D-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3892\/br.2016.701","volume":"5","author":"Kubomura","year":"2016","journal-title":"Biomed. Rep."},{"key":"D0FO01774D-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.peptides.2018.08.001","volume":"107","author":"Li","year":"2018","journal-title":"Peptides"},{"key":"D0FO01774D-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.3390\/ijms18102137","volume":"18","author":"Ma","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"D0FO01774D-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3390\/molecules25010046","volume":"25","author":"Zoghebi","year":"2019","journal-title":"Molecules"},{"key":"D0FO01774D-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/eji.201646551","volume":"47","author":"Galvao","year":"2017","journal-title":"Eur. J. Immunol."},{"key":"D0FO01774D-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"21292","DOI":"10.1074\/jbc.M115.649855","volume":"290","author":"Vanheule","year":"2015","journal-title":"J. Biol. Chem."},{"key":"D0FO01774D-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/0006-2952(86)90077-8","volume":"35","author":"Mackin","year":"1986","journal-title":"Biochem. Pharmacol."},{"key":"D0FO01774D-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5061","DOI":"10.1096\/fj.201902597RR","volume":"34","author":"Han","year":"2020","journal-title":"FASEB J."},{"key":"D0FO01774D-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"153111","DOI":"10.1016\/j.phymed.2019.153111","volume":"66","author":"Cui","year":"2020","journal-title":"Phytomedicine"},{"key":"D0FO01774D-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.peptides.2012.07.030","volume":"37","author":"Nongonierma","year":"2012","journal-title":"Peptides"},{"key":"D0FO01774D-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1136\/jmg.2009.068619","volume":"47","author":"Li","year":"2010","journal-title":"J. Med. Genet."},{"key":"D0FO01774D-(cit28)\/*[position()=1]","first-page":"320","volume":"3","author":"Lee","year":"2010","journal-title":"NDT Plus"},{"key":"D0FO01774D-(cit29)\/*[position()=1]","first-page":"3","volume":"36","author":"Chilappa","year":"2010","journal-title":"Compr. Ther."},{"key":"D0FO01774D-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.virusres.2015.06.004","volume":"208","author":"Di Fiore","year":"2015","journal-title":"Virus Res."},{"key":"D0FO01774D-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2174\/0929866526666190124144027","volume":"26","author":"Liu","year":"2019","journal-title":"Protein Pept. Lett."},{"key":"D0FO01774D-(cit32)\/*[position()=1]","first-page":"E107","volume":"64","author":"Haryono","year":"2018","journal-title":"Kobe J. Med. Sci."},{"key":"D0FO01774D-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"BSR20180215","DOI":"10.1042\/BSR20180215","volume":"38","author":"Bian","year":"2018","journal-title":"Biosci. Rep."},{"key":"D0FO01774D-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"109535","DOI":"10.1016\/j.biopha.2019.109535","volume":"120","author":"Yin","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"D0FO01774D-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"D0FO01774D-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1186\/1471-2105-12-323","volume":"12","author":"Li","year":"2011","journal-title":"BMC Bioinf."},{"key":"D0FO01774D-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comput. Chem."},{"key":"D0FO01774D-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"109195","DOI":"10.1016\/j.biopha.2019.109195","volume":"118","author":"Chen","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"D0FO01774D-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.peptides.2017.01.016","volume":"89","author":"Li","year":"2017","journal-title":"Peptides"},{"key":"D0FO01774D-(cit40)\/*[position()=1]","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/13813455.2019.1702702","author":"Parashar","year":"2019","journal-title":"Arch. Physiol. Biochem."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/FO\/D0FO01774D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:38:30Z","timestamp":1782880710000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/11\/12\/10542-10553\/687016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12,17]]}},"URL":"https:\/\/doi.org\/10.1039\/d0fo01774d","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/D0FO01774D","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Naixin Liu (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-3253-3832","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Xinwang Yang (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-3210-8908","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 7 July 2020; Accepted 20 October 2020; Accepted Manuscript published 21 October 2020; Advance Article published 13 November 2020; Version of Record published 17 December 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}