{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:21:43Z","timestamp":1790752903762,"version":"4.1.0"},"reference-count":69,"publisher":"Royal Society of Chemistry (RSC)","issue":"2","license":[{"start":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T00:00:00Z","timestamp":1607990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"crossref","award":["024.003.001"],"award-info":[{"award-number":["024.003.001"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"crossref","award":["669768"],"award-info":[{"award-number":["669768"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<p>\n                    This organ-on-a-chip device of the outer blood retinal barrier will allow future studies of complex disease mechanisms and treatments of visual disorders using clinically relevant endpoints\n                    <italic>in vitro<\/italic>\n                    .\n                  <\/p>","DOI":"10.1039\/d0lc00639d","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T05:42:03Z","timestamp":1608010923000},"page":"272-283","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":89,"title":["Microfluidic organ-on-a-chip model of the outer blood\u2013retinal barrier with clinically relevant read-outs for tissue permeability and vascular structure"],"prefix":"10.1039","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9528-0145","authenticated-orcid":false,"given":"Yusuf B.","family":"Ar\u0131k","sequence":"first","affiliation":[{"name":"Applied Stem Cell Technologies"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2135-3863","authenticated-orcid":false,"given":"Wesley","family":"Buijsman","sequence":"additional","affiliation":[{"name":"Applied Stem Cell Technologies"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4491-5179","authenticated-orcid":false,"given":"Joshua","family":"Loessberg-Zahl","sequence":"additional","affiliation":[{"name":"BIOS Lab on a Chip group"},{"name":"Technical Medical Centre"},{"name":"MESA+ Institute for Nanotechnology"},{"name":"University of Twente"},{"name":"Enschede"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Cuartas-V\u00e9lez","sequence":"additional","affiliation":[{"name":"Biomedical Photonic Imaging Group"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Veenstra","sequence":"additional","affiliation":[{"name":"Biomedical Photonic Imaging Group"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander","family":"Logtenberg","sequence":"additional","affiliation":[{"name":"Applied Stem Cell Technologies"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Grobbink","sequence":"additional","affiliation":[{"name":"Applied Stem Cell Technologies"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piet","family":"Bergveld","sequence":"additional","affiliation":[{"name":"BIOS Lab on a Chip group"},{"name":"Technical Medical Centre"},{"name":"MESA+ Institute for Nanotechnology"},{"name":"University of Twente"},{"name":"Enschede"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana","family":"Gagliardi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology"},{"name":"Donders Institute for Brain, Cognition and Behaviour"},{"name":"Radboud University Medical Centre"},{"name":"Nijmegen"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0634-5408","authenticated-orcid":false,"given":"Anneke I.","family":"den Hollander","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology"},{"name":"Donders Institute for Brain, Cognition and Behaviour"},{"name":"Radboud University Medical Centre"},{"name":"Nijmegen"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nienke","family":"Bosschaart","sequence":"additional","affiliation":[{"name":"Biomedical Photonic Imaging Group"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9019-933X","authenticated-orcid":false,"given":"Albert","family":"van den Berg","sequence":"additional","affiliation":[{"name":"BIOS Lab on a Chip group"},{"name":"Technical Medical Centre"},{"name":"MESA+ Institute for Nanotechnology"},{"name":"University of Twente"},{"name":"Enschede"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4312-9296","authenticated-orcid":false,"given":"Robert","family":"Passier","sequence":"additional","affiliation":[{"name":"Applied Stem Cell Technologies"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8761-4077","authenticated-orcid":false,"given":"Andries D.","family":"van der Meer","sequence":"additional","affiliation":[{"name":"Applied Stem Cell Technologies"},{"name":"Technical Medical Centre"},{"name":"University of Twente"},{"name":"Enschede"},{"name":"The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D0LC00639D-(cit1)\/*[position()=1]","first-page":"751","volume":"34","author":"Alswailmi","year":"2018","journal-title":"Pak. J. Med. Sci."},{"key":"D0LC00639D-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e106","DOI":"10.1016\/S2214-109X(13)70145-1","volume":"2","author":"Wong","year":"2014","journal-title":"Lancet Glob Health"},{"key":"D0LC00639D-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.neuron.2012.06.018","volume":"75","author":"Ambati","year":"2012","journal-title":"Neuron"},{"key":"D0LC00639D-(cit4)\/*[position()=1]","volume-title":"Ocular Angiogenesis","author":"Hagedorn","year":"2006","unstructured":"C. L. Hagedorn   and  R. A.Adelman , in  Ocular Angiogenesis ,  Springer ,  2006 ,  pp. 3\u201322"},{"key":"D0LC00639D-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/S0140-6736(12)60282-7","volume":"379","author":"Lim","year":"2012","journal-title":"Lancet"},{"key":"D0LC00639D-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/cge.12206","volume":"84","author":"Ratnapriya","year":"2013","journal-title":"Clin. Genet."},{"key":"D0LC00639D-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/ng.3448","volume":"48","author":"Fritsche","year":"2016","journal-title":"Nat. Genet."},{"key":"D0LC00639D-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8614","DOI":"10.1167\/iovs.11-8021","volume":"52","author":"Ablonczy","year":"2011","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"D0LC00639D-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.mam.2012.03.009","volume":"33","author":"Jarrett","year":"2012","journal-title":"Mol. Aspects Med."},{"key":"D0LC00639D-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1039\/B400108G","volume":"3","author":"Boulton","year":"2004","journal-title":"Photochem. Photobiol. Sci."},{"key":"D0LC00639D-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1159\/000316480","volume":"44","author":"Jarrett","year":"2010","journal-title":"Ophthalmic Res."},{"key":"D0LC00639D-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.bbagen.2009.04.016","volume":"1790","author":"Glenn","year":"2009","journal-title":"Biochim. Biophys. Acta, Gen. Subj."},{"key":"D0LC00639D-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1161\/01.CIR.24.1.82","volume":"24","author":"Novotny","year":"1961","journal-title":"Circulation"},{"key":"D0LC00639D-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1038\/eye.2014.214","volume":"28","author":"Castillo","year":"2014","journal-title":"Eye"},{"key":"D0LC00639D-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/ICU.0b013e32835f8bf8","volume":"24","author":"Adhi","year":"2013","journal-title":"Curr. Opin. Ophthalmol."},{"key":"D0LC00639D-(cit16)\/*[position()=1]","volume-title":"AMD book","author":"Arias","year":"2010","unstructured":"L. Arias   and  J.Mon\u00e9s , in  AMD book ,  2010 , ch 7,  pp. 61\u201380"},{"key":"D0LC00639D-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1177\/0300985809359598","volume":"47","author":"Zeiss","year":"2010","journal-title":"Vet. Pathol."},{"key":"D0LC00639D-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3612","DOI":"10.1167\/iovs.05-1622","volume":"47","author":"Maminishkis","year":"2006","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"D0LC00639D-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1126\/science.1188302","volume":"328","author":"Huh","year":"2010","journal-title":"Science"},{"key":"D0LC00639D-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1039\/c2ib00176d","volume":"4","author":"van der Meer","year":"2012","journal-title":"Integr. Biol."},{"key":"D0LC00639D-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.aca.2015.11.023","volume":"903","author":"Du","year":"2016","journal-title":"Anal. Chim. Acta"},{"key":"D0LC00639D-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/nbt.2989","volume":"32","author":"Bhatia","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"D0LC00639D-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1039\/C6LC01590E","volume":"17","author":"Loskill","year":"2017","journal-title":"Lab Chip"},{"key":"D0LC00639D-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1089\/aivt.2016.0003","volume":"2","author":"Hutson","year":"2016","journal-title":"Appl. In Vitro Toxicol."},{"key":"D0LC00639D-(cit25)\/*[position()=1]","first-page":"S337","volume":"21","author":"Bergers","year":"2015","journal-title":"Tissue Eng., Part A"},{"key":"D0LC00639D-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/026119291204000504","volume":"40","author":"Marx","year":"2012","journal-title":"ATLA, Altern. Lab. Anim."},{"key":"D0LC00639D-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1089\/ten.tec.2012.0430","volume":"19","author":"Moya","year":"2013","journal-title":"Tissue Eng., Part C"},{"key":"D0LC00639D-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e0150360","DOI":"10.1371\/journal.pone.0150360","volume":"11","author":"Herland","year":"2016","journal-title":"PLoS One"},{"key":"D0LC00639D-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.tcb.2011.09.005","volume":"21","author":"Huh","year":"2011","journal-title":"Trends Cell Biol."},{"key":"D0LC00639D-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/17460441.2019.1551873","volume":"14","author":"Haderspeck","year":"2019","journal-title":"Expert Opin. Drug Discovery"},{"key":"D0LC00639D-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3538","DOI":"10.1038\/s41598-017-03788-5","volume":"7","author":"Chen","year":"2017","journal-title":"Sci. Rep."},{"key":"D0LC00639D-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e46188","DOI":"10.7554\/eLife.46188","volume":"8","author":"Achberger","year":"2019","journal-title":"eLife"},{"key":"D0LC00639D-(cit33)\/*[position()=1]","volume-title":"Advanced Healthcare Materials","author":"Chung","year":"2017","unstructured":"M. Chung  ,  S.Lee ,  B. J.Lee ,  K.Son ,  N. L.Jeon  and  J. H.Kim ,  Advanced Healthcare Materials ,  2017"},{"issue":"7","key":"D0LC00639D-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7627","DOI":"10.1021\/acsnano.9b00686","volume":"13","author":"Paek","year":"2019","journal-title":"ACS Nano"},{"key":"D0LC00639D-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1039\/C7LC00795G","volume":"18","author":"Yeste","year":"2018","journal-title":"Lab Chip"},{"key":"D0LC00639D-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5414","DOI":"10.1364\/BOE.10.005414","volume":"10","author":"Liu","year":"2019","journal-title":"Biomed. Opt. Express"},{"key":"D0LC00639D-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ebiom.2017.12.014","volume":"27","author":"Pauty","year":"2018","journal-title":"EBioMedicine"},{"key":"D0LC00639D-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10544-012-9699-7","volume":"15","author":"Griep","year":"2013","journal-title":"Biomed. Microdevices"},{"key":"D0LC00639D-(cit39)\/*[position()=1]","first-page":"e56334","volume":"127","author":"van der Helm","year":"2017","journal-title":"J. Visualized Exp."},{"key":"D0LC00639D-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"D0LC00639D-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-51721-9","volume":"9","author":"Veenstra","year":"2019","journal-title":"Sci. Rep."},{"key":"D0LC00639D-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3581","DOI":"10.1364\/BOE.9.003581","volume":"9","author":"Veenstra","year":"2018","journal-title":"Biomed. Opt. Express"},{"key":"D0LC00639D-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1364\/BOE.3.002263","volume":"3","author":"Bosschaart","year":"2012","journal-title":"Biomed. Opt. Express"},{"key":"D0LC00639D-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/j.1469-7580.2007.00812.x","volume":"211","author":"Hamilton","year":"2007","journal-title":"J. Anat."},{"key":"D0LC00639D-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.ejps.2010.04.001","volume":"40","author":"Mannermaa","year":"2010","journal-title":"Eur. J. Pharm. Sci."},{"key":"D0LC00639D-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1177\/0960327107082230","volume":"27","author":"Nevala","year":"2008","journal-title":"Hum. Exp. Toxicol."},{"key":"D0LC00639D-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1111\/jcmm.13175","volume":"21","author":"Spencer","year":"2017","journal-title":"J. Cell. Mol. Med."},{"key":"D0LC00639D-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3034953","DOI":"10.1155\/2017\/3034953","volume":"2017","author":"Moleiro","year":"2017","journal-title":"J. Ophthalmol."},{"key":"D0LC00639D-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1006\/exer.1998.0661","volume":"68","author":"Ballinger","year":"1999","journal-title":"Exp. Eye Res."},{"key":"D0LC00639D-(cit51)\/*[position()=1]","first-page":"180","volume":"12","author":"Goncharov","year":"2018","journal-title":"Biochem. Suppl. Ser. A Membr. Cell Biol."},{"key":"D0LC00639D-(cit52)\/*[position()=1]","volume-title":"Retina","author":"Johnson","year":"2012","unstructured":"R. N. Johnson  ,  A. D.Fu ,  H. R.McDonald ,  J. M.Jumper ,  E.Ai ,  E. T.Cunningham  and  B. J.Lujan , in  Retina ,  Elsevier Inc. , 5th edn,  2012"},{"key":"D0LC00639D-(cit53)\/*[position()=1]","volume-title":"Retinal angiography and optical coherence tomography","author":"Arevalo","year":"2008","unstructured":"J. F. Arevalo  ,  Retinal angiography and optical coherence tomography ,  Springer ,  2008"},{"key":"D0LC00639D-(cit54)\/*[position()=1]","first-page":"9","volume":"46","author":"Papaioannou","year":"2005","journal-title":"Hellenic J. Cardiol."},{"key":"D0LC00639D-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"494","DOI":"10.4161\/auto.5.4.7961","volume":"5","author":"Kurz","year":"2009","journal-title":"Autophagy"},{"key":"D0LC00639D-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1167\/iovs.14-16000","volume":"56","author":"Kim","year":"2015","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"D0LC00639D-(cit57)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1097\/00006982-199919060-00005","volume":"19","author":"Iida","year":"1999","journal-title":"Retina"},{"key":"D0LC00639D-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.ophtha.2010.09.012","volume":"118","author":"Chung","year":"2011","journal-title":"Ophthalmology"},{"key":"D0LC00639D-(cit59)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3663","DOI":"10.1167\/iovs.12-9619","volume":"53","author":"Jirarattanasopa","year":"2012","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"D0LC00639D-(cit60)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1167\/iovs.14-14059","volume":"55","author":"Miyake","year":"2014","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"D0LC00639D-(cit61)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/nprot.2017.018","volume":"12","author":"Chen","year":"2017","journal-title":"Nat. Protoc."},{"key":"D0LC00639D-(cit62)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1089\/ten.tec.2013.0370","volume":"20","author":"Whisler","year":"2012","journal-title":"Tissue Eng., Part C"},{"key":"D0LC00639D-(cit63)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.addr.2018.06.007","volume":"140","author":"Cochrane","year":"2019","journal-title":"Adv. Drug Delivery Rev."},{"key":"D0LC00639D-(cit64)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1039\/c3lc41320a","volume":"13","author":"Kim","year":"2013","journal-title":"Lab Chip"},{"key":"D0LC00639D-(cit65)\/*[position()=1]","volume-title":"Retinal and Choroidal Circulation","author":"Roh","year":"2009","unstructured":"S. Roh   and  J.Weiter ,  Retinal and Choroidal Circulation ,  2009 , ( https:\/\/www.semanticscholar.org\/paper\/Retinal-and-Choroidal-Circulation-Roh-Weiter\/fe640af3a95bd22565b48a1a71a1a6d3502ad45c#citing-papers )"},{"key":"D0LC00639D-(cit66)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.ajo.2015.06.030","volume":"160","author":"Kuehlewein","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"D0LC00639D-(cit67)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.ophtha.2016.01.044","volume":"123","author":"Roisman","year":"2016","journal-title":"Ophthalmology"},{"key":"D0LC00639D-(cit68)\/*[position()=1]","volume-title":"Optical Coherence Tomography in Age-related Macular Degeneration","author":"Garcia-Layana","year":"2017","unstructured":"A. Garcia-Layana  ,  G.Ciuffo ,  J.Zarranz-Ventura  and  A.Alvarez-Vidal ,  Optical Coherence Tomography in Age-related Macular Degeneration ,  2017 ,  https:\/\/amdbook.org\/content\/optical-coherence-tomography-age-related-macular-degeneration"},{"key":"D0LC00639D-(cit69)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e597","DOI":"10.1111\/aos.13399","volume":"95","author":"Koh","year":"2017","journal-title":"Acta Ophthalmol."},{"key":"D0LC00639D-(cit70)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1039\/C8LC00827B","volume":"19","author":"Van Den Berg","year":"2019","journal-title":"Lab Chip"}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/LC\/D0LC00639D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:08:05Z","timestamp":1783015685000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/21\/2\/272-283\/688964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":69,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,1,27]]}},"URL":"https:\/\/doi.org\/10.1039\/d0lc00639d","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/D0LC00639D","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Yusuf B. Ar\u0131k (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-9528-0145","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Wesley Buijsman (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-2135-3863","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Joshua Loessberg-Zahl (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-4491-5179","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Anneke I. den Hollander (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-0634-5408","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Albert van den Berg (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-9019-933X","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Robert Passier (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-4312-9296","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Andries D. van der Meer (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-8761-4077","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 19 June 2020; Accepted 2 December 2020;  Accepted Manuscript published 15 December 2020;  Advance Article published 21 December 2020;  Version of Record published 27 January 2021","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}