{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:06:12Z","timestamp":1782947172532,"version":"3.54.5"},"reference-count":36,"publisher":"Royal Society of Chemistry (RSC)","issue":"25","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"am","delay-in-days":517,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"name":"Ministry of Health and Welfare","award":["HI18C1236"],"award-info":[{"award-number":["HI18C1236"]}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale"],"abstract":"<p>Pulmonary gene delivery system was developed based on RAGE-antagonist peptide and dexamethasone-conjugated polyamidoamine.<\/p>","DOI":"10.1039\/d0nr01367f","type":"journal-article","created":{"date-parts":[[2020,5,31]],"date-time":"2020-05-31T23:43:32Z","timestamp":1590968612000},"page":"13606-13617","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["A RAGE-antagonist peptide potentiates polymeric micelle-mediated intracellular delivery of plasmid DNA for acute lung injury gene therapy"],"prefix":"10.1039","volume":"12","author":[{"given":"Chunxian","family":"Piao","sequence":"first","affiliation":[{"name":"Department of Bioengineering"},{"name":"College of Engineering"},{"name":"Hanyang University"},{"name":"Seoul 04763"},{"name":"Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanyu","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Bioengineering"},{"name":"College of Engineering"},{"name":"Hanyang University"},{"name":"Seoul 04763"},{"name":"Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myoungjee","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Bioengineering"},{"name":"College of Engineering"},{"name":"Hanyang University"},{"name":"Seoul 04763"},{"name":"Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junkyu","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Bioengineering"},{"name":"College of Engineering"},{"name":"Hanyang University"},{"name":"Seoul 04763"},{"name":"Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7083-9296","authenticated-orcid":false,"given":"Minhyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Bioengineering"},{"name":"College of Engineering"},{"name":"Hanyang University"},{"name":"Seoul 04763"},{"name":"Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"D0NR01367F-(cit1)\/*[position()=1]","first-page":"326","volume":"5","author":"Fanelli","year":"2013","journal-title":"J. Thorac. Dis."},{"key":"D0NR01367F-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1056\/NEJM200005043421806","volume":"342","author":"Ware","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"D0NR01367F-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1089\/jamp.2009.0775","volume":"23","author":"Johnson","year":"2010","journal-title":"J. Aerosol Med. Pulm. Drug Delivery"},{"key":"D0NR01367F-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"293","DOI":"10.2119\/molmed.2010.00138","volume":"17","author":"Grommes","year":"2011","journal-title":"Mol. Med."},{"key":"D0NR01367F-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.2174\/092986708785132942","volume":"15","author":"Raghavendran","year":"2008","journal-title":"Curr. Med. Chem."},{"key":"D0NR01367F-(cit6)\/*[position()=1]","first-page":"L379","volume":"295","author":"Matute-Bello","year":"2008","journal-title":"Am. J. Physiol.: Lung Cell. Mol. Physiol."},{"key":"D0NR01367F-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1242\/dmm.006213","volume":"4","author":"Proudfoot","year":"2011","journal-title":"Dis. Models Mech."},{"key":"D0NR01367F-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1159\/000374020","volume":"35","author":"Yin","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"key":"D0NR01367F-(cit9)\/*[position()=1]","first-page":"857","volume":"19","author":"Zhao","year":"2015","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"D0NR01367F-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e269","DOI":"10.1371\/journal.pmed.0040269","volume":"4","author":"Mei","year":"2007","journal-title":"PLoS Med."},{"key":"D0NR01367F-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1600490","DOI":"10.1002\/mabi.201600490","volume":"17","author":"Kim","year":"2017","journal-title":"Macromol. Biosci."},{"key":"D0NR01367F-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1007\/s11095-017-2175-6","volume":"34","author":"Piao","year":"2017","journal-title":"Pharm. Res."},{"key":"D0NR01367F-(cit13)\/*[position()=1]","first-page":"GE01","volume":"9","author":"Ramamoorth","year":"2015","journal-title":"J. Clin. Diagn. Res."},{"key":"D0NR01367F-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jconrel.2011.06.041","volume":"156","author":"Kim","year":"2011","journal-title":"J. Controlled Release"},{"key":"D0NR01367F-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/mt.2009.297","volume":"18","author":"Won","year":"2010","journal-title":"Mol. Ther."},{"key":"D0NR01367F-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6542","DOI":"10.1016\/j.biomaterials.2012.05.046","volume":"33","author":"Park","year":"2012","journal-title":"Biomaterials"},{"key":"D0NR01367F-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nrg3763","volume":"15","author":"Yin","year":"2014","journal-title":"Nat. Rev. Genet."},{"key":"D0NR01367F-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7796","DOI":"10.1038\/ncomms8796","volume":"6","author":"Vettorazzi","year":"2015","journal-title":"Nat. Commun."},{"key":"D0NR01367F-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1089\/ars.2015.6299","volume":"23","author":"Weber","year":"2015","journal-title":"Antioxid. Redox Signaling"},{"key":"D0NR01367F-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1172\/JCI126975","volume":"130","author":"Huebener","year":"2019","journal-title":"J. Clin. Invest."},{"key":"D0NR01367F-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ejps.2017.12.019","volume":"114","author":"Lee","year":"2018","journal-title":"Eur. J. Pharm. Sci."},{"key":"D0NR01367F-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ejphar.2014.01.030","volume":"726","author":"Wang","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"D0NR01367F-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1007\/s00134-007-0748-2","volume":"33","author":"Silva","year":"2007","journal-title":"Intensive Care Med."},{"key":"D0NR01367F-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.jphs.2016.02.005","volume":"130","author":"Izushi","year":"2016","journal-title":"J. Pharmacol. Sci."},{"key":"D0NR01367F-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jconrel.2018.04.021","volume":"279","author":"Choi","year":"2018","journal-title":"J. Controlled Release"},{"key":"D0NR01367F-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jprot.2018.02.010","volume":"177","author":"Downs","year":"2018","journal-title":"J. Proteomics"},{"key":"D0NR01367F-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1146\/annurev-med-041316-085215","volume":"69","author":"Hudson","year":"2018","journal-title":"Annu. Rev. Med."},{"key":"D0NR01367F-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0014-5793(03)00846-9","volume":"550","author":"Ishihara","year":"2003","journal-title":"FEBS Lett."},{"key":"D0NR01367F-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1021\/acsbiomaterials.9b00004","volume":"5","author":"Piao","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"key":"D0NR01367F-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/sj.gt.3301938","volume":"10","author":"Lee","year":"2003","journal-title":"Gene Ther."},{"key":"D0NR01367F-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1002\/mabi.201500058","volume":"15","author":"Jeon","year":"2015","journal-title":"Macromol. Biosci."},{"key":"D0NR01367F-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1021\/bc070012a","volume":"18","author":"Bae","year":"2007","journal-title":"Bioconjugate Chem."},{"key":"D0NR01367F-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijpharm.2006.05.002","volume":"320","author":"Choi","year":"2006","journal-title":"Int. J. Pharm."},{"key":"D0NR01367F-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.biomaterials.2010.08.116","volume":"32","author":"Hyun","year":"2011","journal-title":"Biomaterials"},{"key":"D0NR01367F-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3109\/1061186X.2012.712127","volume":"20","author":"Kim","year":"2012","journal-title":"J. Drug Targeting"},{"key":"D0NR01367F-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1046\/j.1440-1711.2001.01025.x","volume":"79","author":"Adcock","year":"2001","journal-title":"Immunol. Cell Biol."}],"container-title":["Nanoscale"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/NR\/D0NR01367F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:57:47Z","timestamp":1782943067000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nr\/article\/12\/25\/13606-13617\/694399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":36,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2020,7,2]]}},"URL":"https:\/\/doi.org\/10.1039\/d0nr01367f","relation":{},"ISSN":["2040-3364","2040-3372"],"issn-type":[{"value":"2040-3364","type":"print"},{"value":"2040-3372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/D0NR01367F","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Minhyung Lee (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-7083-9296","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Minhyung Lee (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/W-1245-2018","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 18 February 2020; Accepted 28 May 2020;  Accepted Manuscript published 1 June 2020;  Advance Article published 19 June 2020;  Version of Record published 2 July 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}