{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:57:07Z","timestamp":1782943027772,"version":"3.54.5"},"reference-count":34,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T00:00:00Z","timestamp":1661558400000},"content-version":"am","delay-in-days":603,"URL":"http:\/\/rsc.li\/journals-terms-of-use#chorus"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20K15421"],"award-info":[{"award-number":["20K15421"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008884","name":"Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008884","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012018","name":"Research Foundation for Opto-Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009023","name":"Precursory Research for Embryonic Science and Technology","doi-asserted-by":"publisher","award":["JPMJPR20EB"],"award-info":[{"award-number":["JPMJPR20EB"]}],"id":[{"id":"10.13039\/501100009023","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP191m0203012"],"award-info":[{"award-number":["JP191m0203012"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>Bioluminescence (BL) detection of copper in human serum was achieved by developing a caged luciferin. The luciferin reacts only with copper and exhibits luminescence with human serum albumin, which provides a \u201cluciferase-independent\u201d BL copper assay.<\/jats:p>","DOI":"10.1039\/d1an01292d","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T19:41:27Z","timestamp":1630006887000},"page":"6139-6144","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Mix-and-read bioluminescent copper detection platform using a caged coelenterazine analogue"],"prefix":"10.1039","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9539-596X","authenticated-orcid":false,"given":"Ryo","family":"Nishihara","sequence":"first","affiliation":[{"name":"National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan"},{"name":"DAILAB, DBT-AIST International Centre for Translational and Environmental Research (DAICENTER), National Institute of Advanced Industrial Science and Technology (AIST), Central 5-41, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan"},{"name":"Japan Science and Technology Agency (JST), PRESTO, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5666-9561","authenticated-orcid":false,"given":"Ryoji","family":"Kurita","sequence":"additional","affiliation":[{"name":"National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan"},{"name":"DAILAB, DBT-AIST International Centre for Translational and Environmental Research (DAICENTER), National Institute of Advanced Industrial Science and Technology (AIST), Central 5-41, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan"},{"name":"Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1AN01292D\/cit1","doi-asserted-by":"crossref","first-page":"R877","DOI":"10.1016\/j.cub.2011.09.040","volume":"21","author":"Festa","year":"2011","journal-title":"Curr. Biol."},{"key":"D1AN01292D\/cit2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s12011-016-0720-5","volume":"174","author":"Styczen","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"key":"D1AN01292D\/cit3","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3390\/ijms21031069","volume":"21","author":"Baldari","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D1AN01292D\/cit4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1258\/000456303763046021","volume":"40","author":"Walshe","year":"2003","journal-title":"Ann. Clin. Biochem."},{"key":"D1AN01292D\/cit5","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1309\/AJCP7Z9KBFINVGYF","volume":"131","author":"McMillin","year":"2009","journal-title":"Am. J. Clin. Pathol."},{"key":"D1AN01292D\/cit6","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.aca.2005.09.013","volume":"555","author":"Lopes","year":"2006","journal-title":"Anal. Chim. Acta"},{"key":"D1AN01292D\/cit7","doi-asserted-by":"crossref","first-page":"6074","DOI":"10.1021\/ac0700528","volume":"79","author":"Becker","year":"2007","journal-title":"Anal. Chem."},{"key":"D1AN01292D\/cit8","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.talanta.2007.03.060","volume":"73","author":"Zheng","year":"2007","journal-title":"Talanta"},{"key":"D1AN01292D\/cit9","doi-asserted-by":"crossref","first-page":"4950","DOI":"10.1039\/D0AN00563K","volume":"145","author":"Cary","year":"2020","journal-title":"Analyst"},{"key":"D1AN01292D\/cit10","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1039\/C4AY02297A","volume":"7","author":"Zhao","year":"2015","journal-title":"Anal. Methods"},{"key":"D1AN01292D\/cit11","doi-asserted-by":"crossref","first-page":"12637","DOI":"10.1039\/C5CC04218F","volume":"51","author":"Li","year":"2015","journal-title":"Chem. Commun."},{"key":"D1AN01292D\/cit12","doi-asserted-by":"crossref","first-page":"5668","DOI":"10.1039\/D0CS01492C","volume":"50","author":"Syed","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"D1AN01292D\/cit13","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1021\/ac3031724","volume":"85","author":"Ozawa","year":"2013","journal-title":"Anal. Chem."},{"key":"D1AN01292D\/cit14","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1021\/acssensors.0c02000","volume":"6","author":"Itoh","year":"2021","journal-title":"ACS Sens."},{"key":"D1AN01292D\/cit15","first-page":"1","author":"Shimomura","year":"2006","journal-title":"Bioluminescence: Chemical Principles and Methods"},{"key":"D1AN01292D\/cit16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-62703-718-1_1","volume":"1098","author":"Badr","year":"2014","journal-title":"Bioluminescent Imaging: Methods and Protocols"},{"key":"D1AN01292D\/cit17","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1039\/C5PP00456J","volume":"15","author":"Jiang","year":"2016","journal-title":"Photochem. Photobiol. Sci."},{"key":"D1AN01292D\/cit18","doi-asserted-by":"crossref","first-page":"7465","DOI":"10.3390\/ijms21207465","volume":"21","author":"Krasitskaya","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D1AN01292D\/cit19","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1021\/acs.bioconjchem.0c00536","volume":"31","author":"Nishihara","year":"2020","journal-title":"Bioconjugate Chem."},{"key":"D1AN01292D\/cit20","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1039\/C2CS35249D","volume":"42","author":"Li","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"D1AN01292D\/cit21","doi-asserted-by":"crossref","first-page":"10238","DOI":"10.1039\/C7OB01656E","volume":"15","author":"Yuan","year":"2017","journal-title":"Org. Biomol. Chem."},{"key":"D1AN01292D\/cit22","doi-asserted-by":"crossref","first-page":"14219","DOI":"10.1073\/pnas.1613628113","volume":"113","author":"Heffern","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D1AN01292D\/cit23","doi-asserted-by":"crossref","first-page":"14970","DOI":"10.1002\/chem.201302002","volume":"19","author":"Lindberg","year":"2013","journal-title":"Chem. \u2013 Eur. J."},{"key":"D1AN01292D\/cit24","doi-asserted-by":"crossref","first-page":"9546","DOI":"10.1021\/acs.analchem.9b00694","volume":"91","author":"Nomura","year":"2019","journal-title":"Anal. Chem."},{"key":"D1AN01292D\/cit25","doi-asserted-by":"crossref","first-page":"14574","DOI":"10.1039\/C9CC07737E","volume":"55","author":"Yoo","year":"2019","journal-title":"Chem. Commun."},{"key":"D1AN01292D\/cit26","doi-asserted-by":"crossref","first-page":"4487","DOI":"10.1039\/C4CS00292J","volume":"44","author":"Qian","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"D1AN01292D\/cit27","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S1388-1981(99)00148-1","volume":"1441","author":"Curry","year":"1999","journal-title":"Biochim. Biophys. Acta, Mol. Cell Biol. Lipids"},{"key":"D1AN01292D\/cit28","doi-asserted-by":"crossref","first-page":"7916","DOI":"10.1039\/C8SC04041A","volume":"9","author":"Rakshit","year":"2018","journal-title":"Chem. Sci."},{"key":"D1AN01292D\/cit29","doi-asserted-by":"crossref","first-page":"5938","DOI":"10.1021\/ja100714p","volume":"132","author":"Taki","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"D1AN01292D\/cit30","doi-asserted-by":"crossref","first-page":"761264","DOI":"10.1155\/2014\/761264","volume":"2014","author":"Rahal","year":"2014","journal-title":"BioMed. Res. Int."},{"key":"D1AN01292D\/cit31","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1080\/02772248.2013.792559","volume":"95","author":"Kerger","year":"2013","journal-title":"Toxicol. Environ. Chem."},{"key":"D1AN01292D\/cit32","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1093\/clinchem\/35.4.552","volume":"35","author":"Abe","year":"1989","journal-title":"Clin. Chem."},{"key":"D1AN01292D\/cit33","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jtemb.2017.11.006","volume":"45","author":"Catalani","year":"2018","journal-title":"J. Trace Elem. Med. Biol."},{"key":"D1AN01292D\/cit34","doi-asserted-by":"crossref","first-page":"15057","DOI":"10.1021\/acs.inorgchem.7b02397","volume":"56","author":"Sendzik","year":"2017","journal-title":"Inorg. Chem."}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/AN\/D1AN01292D","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/AN\/D1AN01292D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:24:02Z","timestamp":1782941042000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/146\/20\/6139-6144\/714680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":34,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2021,10,11]]}},"URL":"https:\/\/doi.org\/10.1039\/d1an01292d","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}