{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:35:11Z","timestamp":1782884111457,"version":"3.54.5"},"reference-count":29,"publisher":"Royal Society of Chemistry (RSC)","issue":"17","license":[{"start":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:00:00Z","timestamp":1647648000000},"content-version":"am","delay-in-days":442,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21727809"],"award-info":[{"award-number":["21727809"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"crossref","award":["QYZDJ-SSW-SLH034"],"award-info":[{"award-number":["QYZDJ-SSW-SLH034"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Anal. Methods"],"abstract":"<p>\n                    We proposed an idea of separation-interrupted sequential injections (Sisi) to substantially increase the throughput of CE together with theory and experimental demonstration. The separation time of Sisi-CE-C\n                    <sup>4<\/sup>\n                    D\/C\n                    <sup>4<\/sup>\n                    D is only 21% of that of normal CE.\n                  <\/p>","DOI":"10.1039\/d1ay00223f","type":"journal-article","created":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T04:54:13Z","timestamp":1616129653000},"page":"1995-2004","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A substantial increase of analytical throughput in capillary electrophoresis throughput by separation-interrupted sequential injections"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3417-5007","authenticated-orcid":false,"given":"Hongliang","family":"Li","sequence":"first","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Living Biosystems"},{"name":"Institute of Chemistry"},{"name":"Chinese Academy of Sciences"},{"name":"Beijing 100190"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7929-822X","authenticated-orcid":false,"given":"Chao","family":"Guo","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Living Biosystems"},{"name":"Institute of Chemistry"},{"name":"Chinese Academy of Sciences"},{"name":"Beijing 100190"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6199-3021","authenticated-orcid":false,"given":"Qianchun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemical Synthesis and Environmental Pollution Control-Remediation Technology of Guizhou Province"},{"name":"School of Biology and Chemistry"},{"name":"Xingyi Normal University for Nationalities"},{"name":"Xingyi 562400"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linchun","family":"Bao","sequence":"additional","affiliation":[{"name":"Clinical Laboratory"},{"name":"Qian Xi Nan People's Hospital"},{"name":"Xingyi 562400"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingfeng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Living Biosystems"},{"name":"Institute of Chemistry"},{"name":"Chinese Academy of Sciences"},{"name":"Beijing 100190"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenpeng","family":"Guo","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Living Biosystems"},{"name":"Institute of Chemistry"},{"name":"Chinese Academy of Sciences"},{"name":"Beijing 100190"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Living Biosystems"},{"name":"Institute of Chemistry"},{"name":"Chinese Academy of Sciences"},{"name":"Beijing 100190"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1AY00223F-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1007\/s00216-012-6039-y","volume":"403","author":"Vuckovic","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"D1AY00223F-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10404","DOI":"10.1039\/C9CC05553C","volume":"55","author":"Li","year":"2019","journal-title":"Chem. Commun."},{"key":"D1AY00223F-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1039\/C6TB02836E","volume":"5","author":"Jiang","year":"2017","journal-title":"J. Mater. Chem. B"},{"key":"D1AY00223F-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"115323","DOI":"10.1016\/j.trac.2018.11.021","volume":"120","author":"Miggiels","year":"2019","journal-title":"TrAC, Trends Anal. Chem."},{"key":"D1AY00223F-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"115302","DOI":"10.1016\/j.trac.2018.11.001","volume":"120","author":"Lv","year":"2019","journal-title":"TrAC, Trends Anal. Chem."},{"key":"D1AY00223F-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1021\/acs.analchem.9b04713","volume":"92","author":"Kaplitz","year":"2020","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1002\/anie.201812974","volume":"58","author":"Le","year":"2019","journal-title":"Angew. Chem."},{"key":"D1AY00223F-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1021\/acs.analchem.8b00015","volume":"90","author":"Voeten","year":"2018","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.chroma.2018.10.005","volume":"1583","author":"Cieslarova","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"D1AY00223F-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7819","DOI":"10.1021\/acs.analchem.9b01516","volume":"91","author":"Duncan","year":"2019","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1002\/(SICI)1522-2683(19990601)20:7<1492::AID-ELPS1492>3.0.CO;2-V","volume":"20","author":"Behr","year":"1999","journal-title":"Electrophoresis"},{"key":"D1AY00223F-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1002\/1521-3773(20001215)39:24<4463::AID-ANIE4463>3.0.CO;2-8","volume":"39","author":"Dovichi","year":"2000","journal-title":"Angew. Chem., Int. Ed."},{"key":"D1AY00223F-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1021\/ac102437z","volume":"83","author":"Chambers","year":"2011","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6069","DOI":"10.1007\/s00216-014-7993-3","volume":"406","author":"Mark","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"D1AY00223F-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1039\/C2LC40720E","volume":"13","author":"Liao","year":"2013","journal-title":"Lab Chip"},{"key":"D1AY00223F-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1021\/ac900573x","volume":"81","author":"Zhang","year":"2009","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit17)\/*[position()=1]","first-page":"1681","volume":"36","author":"Hu","year":"2015","journal-title":"Chem. Res. Chin. Univ."},{"key":"D1AY00223F-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10664","DOI":"10.1021\/ac403171u","volume":"85","author":"Kuehnbaum","year":"2013","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1021\/acs.analchem.8b05054","volume":"91","author":"Azab","year":"2019","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1039\/D0AY00384K","volume":"12","author":"Guo","year":"2020","journal-title":"Anal. Methods"},{"key":"D1AY00223F-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1002\/elps.201000252","volume":"31","author":"Yang","year":"2010","journal-title":"Electrophoresis"},{"key":"D1AY00223F-(cit22)\/*[position()=1]","volume-title":"Capillary Electrophoresis Technology and Application","author":"Yi","year":"2019","unstructured":"C. Yi  Capillary Electrophoresis Technology and Application ,  2019"},{"key":"D1AY00223F-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1700310","DOI":"10.1002\/pmic.201700310","volume":"17","author":"Faserl","year":"2017","journal-title":"Proteomics"},{"key":"D1AY00223F-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.chroma.2017.07.022","volume":"1523","author":"Boley","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"D1AY00223F-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.aca.2008.05.062","volume":"622","author":"Liu","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"D1AY00223F-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/BF01448214","volume":"17","author":"Bleazard","year":"1996","journal-title":"Int. J. Thermophys."},{"key":"D1AY00223F-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.1021\/acs.analchem.5b04666","volume":"88","author":"Koenka","year":"2016","journal-title":"Anal. Chem."},{"key":"D1AY00223F-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4113","DOI":"10.1007\/s00216-018-1507-7","volume":"411","author":"Guo","year":"2019","journal-title":"Anal. Bioanal. Chem."},{"key":"D1AY00223F-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.chroma.2014.10.085","volume":"1372","author":"S\u00e1iz","year":"2014","journal-title":"J. Chromatogr. A"}],"container-title":["Analytical Methods"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/AY\/D1AY00223F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:23:42Z","timestamp":1782879822000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ay\/article\/13\/17\/1995-2004\/715114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":29,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2021,5,6]]}},"URL":"https:\/\/doi.org\/10.1039\/d1ay00223f","relation":{},"ISSN":["1759-9660","1759-9679"],"issn-type":[{"value":"1759-9660","type":"print"},{"value":"1759-9679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/D1AY00223F","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Hongliang Li (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-3417-5007","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Chao Guo (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-7929-822X","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Qianchun Zhang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-6199-3021","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 6 February 2021; Accepted 19 March 2021;  Accepted Manuscript published 19 March 2021;  Advance Article published 14 April 2021;  Version of Record published 6 May 2021","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}