{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:22:55Z","timestamp":1784658175889,"version":"3.55.0"},"reference-count":51,"publisher":"Royal Society of Chemistry (RSC)","issue":"18","license":[{"start":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T00:00:00Z","timestamp":1657670400000},"content-version":"am","delay-in-days":558,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["2020GXNSFAA159134"],"award-info":[{"award-number":["2020GXNSFAA159134"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012543","name":"Youth Science Foundation of Guangxi Medical University","doi-asserted-by":"publisher","award":["GXMUYSF201905"],"award-info":[{"award-number":["GXMUYSF201905"]}],"id":[{"id":"10.13039\/501100012543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81760485"],"award-info":[{"award-number":["81760485"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018571","name":"Specific Research Project of Guangxi for Research Bases and Talents","doi-asserted-by":"publisher","award":["GuikeAD21075002"],"award-info":[{"award-number":["GuikeAD21075002"]}],"id":[{"id":"10.13039\/501100018571","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013091","name":"Science and Technology Major Project of Guangxi","doi-asserted-by":"publisher","award":["GuikeAA19254002"],"award-info":[{"award-number":["GuikeAA19254002"]}],"id":[{"id":"10.13039\/501100013091","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>Reacting with reactive oxygen species (ROS) by C\u2013H hydrogen abstraction, carbazate modified sephadex served as potent ROS scavengers, with excellent antioxidant and anti-inflammatory abilities, finally suppressing the progress of osteoarthritis.<\/jats:p>","DOI":"10.1039\/d1bm00743b","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T05:24:46Z","timestamp":1626153886000},"page":"6236-6250","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Carbazate-modified cross-linked dextran microparticles suppress the progression of osteoarthritis by ROS scavenging"],"prefix":"10.1039","volume":"9","author":[{"given":"Yanfeng","family":"Ding","sequence":"first","affiliation":[{"name":"Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhimin","family":"Li","sequence":"additional","affiliation":[{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Division of Spine Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenwen","family":"Hu","sequence":"additional","affiliation":[{"name":"Life Sciences Institute, Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianjing","family":"Feng","sequence":"additional","affiliation":[{"name":"Pharmaceutical College, Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[{"name":"Life Sciences Institute, Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohua","family":"Yan","sequence":"additional","affiliation":[{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Department of Orthopaedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonglin","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhu","sequence":"additional","affiliation":[{"name":"Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yao","sequence":"additional","affiliation":[{"name":"Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9666-0024","authenticated-orcid":false,"given":"Li","family":"Zheng","sequence":"additional","affiliation":[{"name":"Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maolin","family":"He","sequence":"additional","affiliation":[{"name":"Division of Spine Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7590-3306","authenticated-orcid":false,"given":"Ming","family":"Gao","sequence":"additional","affiliation":[{"name":"Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1047-8820","authenticated-orcid":false,"given":"Jinmin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Department of Orthopaedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China"},{"name":"Guangxi Key Liboratory of Regenerative Medicine, Guangxi Medical University, Nanning, 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1BM00743B\/cit1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.biomaterials.2019.02.006","volume":"200","author":"Zhang","year":"2019","journal-title":"Biomaterials"},{"issue":"7","key":"D1BM00743B\/cit2","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/nrrheum.2016.65","volume":"12","author":"Loeser","year":"2016","journal-title":"Nat. Rev. Rheumatol."},{"issue":"1","key":"D1BM00743B\/cit3","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1136\/annrheumdis-2017-212863","volume":"78","author":"Ji","year":"2019","journal-title":"Ann. Rheum. Dis."},{"key":"D1BM00743B\/cit4","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.ejmech.2018.07.045","volume":"156","author":"Andersen","year":"2018","journal-title":"Eur. J. Med. Chem."},{"issue":"4","key":"D1BM00743B\/cit5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.bbadis.2016.01.003","volume":"1862","author":"Lepetsos","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"issue":"4","key":"D1BM00743B\/cit6","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/jpi.12362","volume":"61","author":"Hosseinzadeh","year":"2016","journal-title":"J. Pineal Res."},{"issue":"4","key":"D1BM00743B\/cit7","doi-asserted-by":"crossref","first-page":"e1602506","DOI":"10.1126\/sciadv.1602506","volume":"3","author":"Chiang","year":"2017","journal-title":"Sci. Adv."},{"issue":"20","key":"D1BM00743B\/cit8","doi-asserted-by":"crossref","first-page":"5808","DOI":"10.1002\/anie.201802309","volume":"57","author":"Zeng","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"issue":"10","key":"D1BM00743B\/cit9","doi-asserted-by":"crossref","first-page":"11552","DOI":"10.1021\/acsnano.9b05075","volume":"13","author":"Yan","year":"2019","journal-title":"ACS Nano"},{"issue":"7","key":"D1BM00743B\/cit10","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1002\/adma.201503893","volume":"28","author":"Zhang","year":"2016","journal-title":"Adv. Mater."},{"issue":"5","key":"D1BM00743B\/cit11","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.1021\/nn300291r","volume":"6","author":"Chen","year":"2012","journal-title":"ACS Nano"},{"issue":"18","key":"D1BM00743B\/cit12","doi-asserted-by":"crossref","first-page":"5860","DOI":"10.1021\/jacs.5b12070","volume":"138","author":"Zhang","year":"2016","journal-title":"J. Am. Chem. Soc."},{"issue":"11","key":"D1BM00743B\/cit13","doi-asserted-by":"crossref","first-page":"13382","DOI":"10.1021\/acsnano.9b06780","volume":"13","author":"Li","year":"2019","journal-title":"ACS Nano"},{"issue":"15","key":"D1BM00743B\/cit14","doi-asserted-by":"crossref","first-page":"12453","DOI":"10.1021\/acsami.8b01245","volume":"10","author":"Chen","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"2","key":"D1BM00743B\/cit15","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1021\/acs.nanolett.9b05218","volume":"20","author":"Hou","year":"2020","journal-title":"Nano Lett."},{"issue":"48","key":"D1BM00743B\/cit16","doi-asserted-by":"crossref","first-page":"1904833","DOI":"10.1002\/adfm.201904833","volume":"29","author":"Sun","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"3","key":"D1BM00743B\/cit17","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.cclet.2018.10.010","volume":"30","author":"Wang","year":"2019","journal-title":"Chin. Chem. Lett."},{"issue":"3","key":"D1BM00743B\/cit18","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1183\/09031936.93.06030440","volume":"6","author":"Sala","year":"1993","journal-title":"Eur. Respir. J."},{"issue":"10","key":"D1BM00743B\/cit19","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1161\/CIRCULATIONAHA.117.027575","volume":"136","author":"Pasupathy","year":"2017","journal-title":"Circulation"},{"issue":"1\u20132","key":"D1BM00743B\/cit20","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s11010-014-2232-y","volume":"399","author":"Rageh","year":"2015","journal-title":"Mol. Cell. Biochem."},{"issue":"12","key":"D1BM00743B\/cit21","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.biopsych.2007.04.020","volume":"62","author":"Guo","year":"2007","journal-title":"Biol. Psychiatry"},{"issue":"10","key":"D1BM00743B\/cit22","doi-asserted-by":"crossref","first-page":"1800781","DOI":"10.1002\/advs.201800781","volume":"5","author":"Li","year":"2018","journal-title":"Adv. Sci."},{"issue":"8","key":"D1BM00743B\/cit23","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1002\/adhm.201300576","volume":"3","author":"Yoshitomi","year":"2014","journal-title":"Adv. Healthcare Mater."},{"issue":"72","key":"D1BM00743B\/cit24","doi-asserted-by":"crossref","first-page":"7959","DOI":"10.1039\/c3cc44627a","volume":"49","author":"Kim","year":"2013","journal-title":"Chem. Commun."},{"key":"D1BM00743B\/cit25","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.carbpol.2019.04.011","volume":"216","author":"\u0160edov\u00e1","year":"2019","journal-title":"Carbohydr. Polym."},{"issue":"10","key":"D1BM00743B\/cit26","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1021\/bm900701m","volume":"10","author":"Kadi","year":"2009","journal-title":"Biomacromolecules"},{"key":"D1BM00743B\/cit27","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3390\/molecules23030546","volume":"23","author":"Wang","year":"2018","journal-title":"Molecules"},{"issue":"7","key":"D1BM00743B\/cit28","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.cclet.2020.02.032","volume":"31","author":"He","year":"2020","journal-title":"Chin. Chem. Lett."},{"issue":"3","key":"D1BM00743B\/cit29","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1017\/S0007114512001225","volume":"109","author":"Weill","year":"2013","journal-title":"Br. J. Nutr."},{"key":"D1BM00743B\/cit30","doi-asserted-by":"crossref","first-page":"115727","DOI":"10.1016\/j.carbpol.2019.115727","volume":"231","author":"Yang","year":"2020","journal-title":"Carbohydr. Polym."},{"key":"D1BM00743B\/cit31","doi-asserted-by":"crossref","first-page":"115802","DOI":"10.1016\/j.carbpol.2019.115802","volume":"232","author":"Zhou","year":"2020","journal-title":"Carbohydr. Polym."},{"issue":"30","key":"D1BM00743B\/cit32","doi-asserted-by":"crossref","first-page":"6076","DOI":"10.1016\/j.biomaterials.2009.07.054","volume":"30","author":"Gurski","year":"2009","journal-title":"Biomaterials"},{"issue":"13","key":"D1BM00743B\/cit33","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/0142-9612(95)94907-3","volume":"16","author":"Toufik","year":"1995","journal-title":"Biomaterials"},{"issue":"2","key":"D1BM00743B\/cit34","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/0142-9612(87)90097-4","volume":"8","author":"Aubert","year":"1987","journal-title":"Biomaterials"},{"issue":"11","key":"D1BM00743B\/cit35","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1021\/bm060385z","volume":"7","author":"Vlugt-Wensink","year":"2006","journal-title":"Biomacromolecules"},{"issue":"6","key":"D1BM00743B\/cit36","first-page":"652","volume":"40","author":"Shin","year":"2014","journal-title":"Dermatol. Surg."},{"key":"D1BM00743B\/cit37","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijpharm.2004.05.009","volume":"280","author":"Tafaghodi","year":"2004","journal-title":"Int. J. Pharm."},{"issue":"3","key":"D1BM00743B\/cit38","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3109\/10611860903434035","volume":"18","author":"Tafaghodi","year":"2010","journal-title":"J. Drug Targeting"},{"issue":"3","key":"D1BM00743B\/cit39","first-page":"723","volume":"11","author":"Ariaee","year":"2012","journal-title":"Iran. J. Pharm. Res."},{"issue":"28","key":"D1BM00743B\/cit40","doi-asserted-by":"crossref","first-page":"31205","DOI":"10.1021\/acsami.0c07886","volume":"12","author":"Liu","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D1BM00743B\/cit41","doi-asserted-by":"crossref","first-page":"108779","DOI":"10.1016\/j.foodres.2019.108779","volume":"128","author":"Doost","year":"2020","journal-title":"Food Res. Int."},{"issue":"4","key":"D1BM00743B\/cit42","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1021\/tx800465m","volume":"22","author":"Cai","year":"2009","journal-title":"Chem. Res. Toxicol."},{"issue":"9","key":"D1BM00743B\/cit43","doi-asserted-by":"crossref","first-page":"4882","DOI":"10.1073\/pnas.95.9.4882","volume":"95","author":"Uchida","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D1BM00743B\/cit44","doi-asserted-by":"crossref","first-page":"119601","DOI":"10.1016\/j.biomaterials.2019.119601","volume":"230","author":"Liang","year":"2020","journal-title":"Biomaterials"},{"issue":"6","key":"D1BM00743B\/cit45","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/nm.4324","volume":"23","author":"Jeon","year":"2017","journal-title":"Nat. Med."},{"issue":"6","key":"D1BM00743B\/cit46","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/nm.3143","volume":"19","author":"Zhen","year":"2013","journal-title":"Nat. Med."},{"issue":"6","key":"D1BM00743B\/cit47","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1016\/j.actbio.2012.03.015","volume":"8","author":"Eswaramoorthy","year":"2012","journal-title":"Acta Biomater."},{"issue":"1","key":"D1BM00743B\/cit48","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.joca.2005.07.014","volume":"14","author":"Pritzker","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"issue":"16","key":"D1BM00743B\/cit49","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1080\/09205063.2014.951246","volume":"25","author":"Jianping","year":"2014","journal-title":"J. Biomater. Sci., Polym. Ed."},{"issue":"4","key":"D1BM00743B\/cit50","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1074\/jbc.R118.003214","volume":"294","author":"Hauck","year":"2019","journal-title":"J. Biol. Chem."},{"issue":"9","key":"D1BM00743B\/cit51","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/nrrheum.2015.70","volume":"11","author":"Hardin","year":"2015","journal-title":"Nat. Rev. Rheumatol."}],"updated-by":[{"DOI":"10.1039\/d3bm90019c","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T00:00:00Z","timestamp":1678060800000}}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/BM\/D1BM00743B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:47:05Z","timestamp":1782884825000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/9\/18\/6236-6250\/715986"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":51,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2021,9,14]]}},"URL":"https:\/\/doi.org\/10.1039\/d1bm00743b","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}