{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T22:01:08Z","timestamp":1782943268556,"version":"3.54.5"},"reference-count":24,"publisher":"Royal Society of Chemistry (RSC)","issue":"91","license":[{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"am","delay-in-days":656,"URL":"http:\/\/rsc.li\/journals-terms-of-use#chorus"}],"funder":[{"DOI":"10.13039\/100000147","name":"Division of Civil, Mechanical and Manufacturing Innovation","doi-asserted-by":"publisher","award":["2038057"],"award-info":[{"award-number":["2038057"]}],"id":[{"id":"10.13039\/100000147","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007231","name":"Cornell University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007231","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Commun."],"abstract":"<jats:p>\n                    Gly mutations in the 1022\n                    <jats:sup>nd<\/jats:sup>\n                    \u00a0site led to increased stable short \u03b2-structures with new H-bonds, thereby stiffness, whereas mutations in the 1025\n                    <jats:sup>th<\/jats:sup>\n                    \u00a0site disrupted and decreased existing H-bonds, leading to more intensive fluctuations.\n                  <\/jats:p>","DOI":"10.1039\/d1cc05277b","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T06:24:32Z","timestamp":1634624672000},"page":"12183-12186","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Specific osteogenesis imperfecta-related Gly substitutions in type I collagen induce distinct structural, mechanical, and dynamic characteristics"],"prefix":"10.1039","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9238-0623","authenticated-orcid":false,"given":"Haoyuan","family":"Shi","sequence":"first","affiliation":[{"name":"J2 Lab for Engineering Living Materials, Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3032-6330","authenticated-orcid":false,"given":"Liming","family":"Zhao","sequence":"additional","affiliation":[{"name":"J2 Lab for Engineering Living Materials, Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2913-3328","authenticated-orcid":false,"given":"Chenxi","family":"Zhai","sequence":"additional","affiliation":[{"name":"J2 Lab for Engineering Living Materials, Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6462-7422","authenticated-orcid":false,"given":"Jingjie","family":"Yeo","sequence":"additional","affiliation":[{"name":"J2 Lab for Engineering Living Materials, Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1CC05277B\/cit1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.trsl.2016.11.005","volume":"181","author":"Kang","year":"2017","journal-title":"Transl. Res."},{"key":"D1CC05277B\/cit2","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/S0140-6736(15)00728-X","volume":"387","author":"Forlino","year":"2016","journal-title":"Lancet"},{"key":"D1CC05277B\/cit3","doi-asserted-by":"crossref","first-page":"19228","DOI":"10.1074\/jbc.273.30.19228","volume":"273","author":"Hammami-Hauasli","year":"1998","journal-title":"J. Biol. Chem."},{"key":"D1CC05277B\/cit4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1146\/annurev.bb.20.060191.001033","volume":"20","author":"Engel","year":"1991","journal-title":"Annu. Rev. Biophys. Biophys. Chem."},{"key":"D1CC05277B\/cit5","doi-asserted-by":"crossref","first-page":"4195","DOI":"10.1073\/pnas.0812516106","volume":"106","author":"Erat","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D1CC05277B\/cit6","doi-asserted-by":"crossref","first-page":"e1004465","DOI":"10.1371\/journal.pgen.1004465","volume":"10","author":"Cabral","year":"2014","journal-title":"PLoS Genet."},{"key":"D1CC05277B\/cit7","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.3390\/ijms19051407","volume":"19","author":"Arseni","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"D1CC05277B\/cit8","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.bpj.2016.05.038","volume":"111","author":"Varma","year":"2016","journal-title":"Biophys. J."},{"key":"D1CC05277B\/cit9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jmbbm.2018.06.021","volume":"86","author":"Ghanaeian","year":"2018","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"D1CC05277B\/cit10","doi-asserted-by":"crossref","first-page":"103835","DOI":"10.1016\/j.jmbbm.2020.103835","volume":"108","author":"Bourne","year":"2020","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"D1CC05277B\/cit11","doi-asserted-by":"crossref","first-page":"e1009079","DOI":"10.1371\/journal.pcbi.1009079","volume":"17","author":"Hartmann","year":"2021","journal-title":"PLoS Comput. Biol."},{"key":"D1CC05277B\/cit12","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1021\/acs.biomac.6b01808","volume":"18","author":"Clements","year":"2017","journal-title":"Biomacromolecules"},{"key":"D1CC05277B\/cit13","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1093\/bioinformatics\/bth247","volume":"20","author":"Rainey","year":"2004","journal-title":"Bioinformatics"},{"key":"D1CC05277B\/cit14","doi-asserted-by":"crossref","first-page":"26536","DOI":"10.1038\/srep26536","volume":"6","author":"Ribeiro","year":"2016","journal-title":"Sci. Rep."},{"key":"D1CC05277B\/cit15","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0263-7855(96)00018-5","volume":"14","author":"Humphrey","year":"1996","journal-title":"J. Mol. Graphics"},{"key":"D1CC05277B\/cit16","doi-asserted-by":"crossref","first-page":"44130","DOI":"10.1063\/5.0014475","volume":"153","author":"Phillips","year":"2020","journal-title":"J. Chem. Phys."},{"key":"D1CC05277B\/cit17","first-page":"861","volume":"2015","author":"Vanommeslaeghe","year":"1850","journal-title":"Biochim. Biophys. Acta, Gen. Subj."},{"key":"D1CC05277B\/cit18","doi-asserted-by":"crossref","first-page":"3779","DOI":"10.1529\/biophysj.107.122028","volume":"94","author":"Adamovic","year":"2008","journal-title":"Biophys. J."},{"key":"D1CC05277B\/cit19","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1214\/aos\/1176347265","volume":"17","author":"Kunsch","year":"1989","journal-title":"Ann. Stat."},{"key":"D1CC05277B\/cit20","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/cm.21429","volume":"75","author":"Shamloo","year":"2018","journal-title":"Cytoskeleton"},{"key":"D1CC05277B\/cit21","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9781139022217","volume-title":"Mechanics of the Cell","author":"Boal","year":"2012","unstructured":"D.Boal ,  Mechanics of the Cell ,  Cambridge University Press ,  Cambridge , 2nd edn,  2012"},{"key":"D1CC05277B\/cit22","doi-asserted-by":"crossref","first-page":"174105","DOI":"10.1063\/1.3565032","volume":"134","author":"Prinz","year":"2011","journal-title":"J. Chem. Phys."},{"key":"D1CC05277B\/cit23","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1146\/annurev.biochem.77.032207.120833","volume":"78","author":"Shoulders","year":"2009","journal-title":"Annu. Rev. Biochem."},{"key":"D1CC05277B\/cit24","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1021\/cr900095e","volume":"110","author":"Bahar","year":"2010","journal-title":"Chem. Rev."}],"container-title":["Chemical Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/CC\/D1CC05277B","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/CC\/D1CC05277B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:29:29Z","timestamp":1782941369000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cc\/article\/57\/91\/12183-12186\/718414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":24,"journal-issue":{"issue":"91","published-print":{"date-parts":[[2021,11,16]]}},"URL":"https:\/\/doi.org\/10.1039\/d1cc05277b","relation":{},"ISSN":["1359-7345","1364-548X"],"issn-type":[{"value":"1359-7345","type":"print"},{"value":"1364-548X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}