{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:02:44Z","timestamp":1787004164236,"version":"build-2736575974"},"reference-count":47,"publisher":"Royal Society of Chemistry (RSC)","issue":"18","license":[{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"am","delay-in-days":571,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005669","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Estado da Para\u00edba","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005669","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    Carboxymethyl-glucan (CMG) is a derivative of \u03b2-\n                    <jats:sc>d<\/jats:sc>\n                    -glucan extracted from\n                    <jats:italic>Sacharomyces cerevisae<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1039\/d1fo01079d","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T11:05:01Z","timestamp":1627297501000},"page":"8552-8560","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Carboxymethyl-glucan from\n                    <i>Saccharomyces cerevisiae<\/i>\n                    reduces blood pressure and improves baroreflex sensitivity in spontaneously hypertensive rats"],"prefix":"10.1039","volume":"12","author":[{"given":"Lorena Soares","family":"Bezerra","sequence":"first","affiliation":[{"name":"Post-Graduate Program in Nutritional Sciences, Health Sciences Center, Federal University of Para\u00edba (Universidade Federal da Para\u00edba \u2013 UFPB), Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7771-0479","authenticated-orcid":false,"given":"Marciane","family":"Magnani","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Nutritional Sciences, Health Sciences Center, Federal University of Para\u00edba (Universidade Federal da Para\u00edba \u2013 UFPB), Brazil"},{"name":"Department of Food Engineering, Federal University of Para\u00edba (UFPB), Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana Colombo","family":"Pimentel","sequence":"additional","affiliation":[{"name":"Federal Institute of Paran\u00e1 (IFPR), Campus Paranava\u00ed, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisca Manuela de Souza","family":"Freire","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Health Sciences Center, UFPB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tays Amanda Felisberto","family":"da Silva","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Natural and Synthetic Bioactive Products, Health Sciences Center, UFPB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Cartaxo","family":"Ramalho","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Health Sciences Center, UFPB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano Francisco","family":"Alves","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathology, Laboratory of Pathology, Health Sciences Center, UFPB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luiz","family":"de Brito Alves","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Nutritional Sciences, Health Sciences Center, Federal University of Para\u00edba (Universidade Federal da Para\u00edba \u2013 UFPB), Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isac Almeida","family":"de Medeiros","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Natural and Synthetic Bioactive Products, Health Sciences Center, UFPB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robson Cavalcante","family":"Veras","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Nutritional Sciences, Health Sciences Center, Federal University of Para\u00edba (Universidade Federal da Para\u00edba \u2013 UFPB), Brazil"},{"name":"Department of Pharmaceutical Sciences, Health Sciences Center, UFPB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1FO01079D\/cit1","first-page":"133","volume":"2","author":"Ahmad","year":"2012","journal-title":"J. Nutr. Food Sci."},{"key":"D1FO01079D\/cit2","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3390\/medicina43080076","volume":"43","author":"Akramiene","year":"2007","journal-title":"Medicina"},{"key":"D1FO01079D\/cit3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/15476910802019045","volume":"5","author":"Novak","year":"2008","journal-title":"J. Immunotoxicol."},{"key":"D1FO01079D\/cit4","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2174\/0929867003374705","volume":"7","author":"Ooi","year":"2000","journal-title":"Curr. Med. Chem."},{"key":"D1FO01079D\/cit5","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1084\/jem.20021890","volume":"197","author":"Brown","year":"2003","journal-title":"J. Exp. Med."},{"key":"D1FO01079D\/cit6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0304-3835(03)00336-7","volume":"198","author":"Slame\u0148ov\u00e1","year":"2003","journal-title":"Cancer Lett."},{"key":"D1FO01079D\/cit7","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1756-8722-2-25","volume":"2","author":"Chan","year":"2009","journal-title":"J. Hematol. Oncol."},{"key":"D1FO01079D\/cit8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3109\/09537100903359306","volume":"21","author":"Saluk-Juszczak","year":"2010","journal-title":"Platelets"},{"key":"D1FO01079D\/cit9","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/j.1753-4887.2012.00494.x","volume":"70","author":"Cloetens","year":"2012","journal-title":"Nutr. Rev."},{"key":"D1FO01079D\/cit10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.tifs.2014.09.002","volume":"41","author":"Du","year":"2015","journal-title":"Trends Food Sci. Technol."},{"key":"D1FO01079D\/cit11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.tifs.2019.03.023","volume":"88","author":"Bai","year":"2019","journal-title":"Trends Food Sci. Technol."},{"key":"D1FO01079D\/cit12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.ijbiomac.2014.09.008","volume":"72","author":"Kagimura","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"key":"D1FO01079D\/cit13","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1016\/j.carres.2006.05.024","volume":"341","author":"Tao","year":"2006","journal-title":"Carbohydr. Res."},{"key":"D1FO01079D\/cit14","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.carbpol.2009.05.023","volume":"78","author":"Magnani","year":"2009","journal-title":"Carbohydr. Polym."},{"key":"D1FO01079D\/cit15","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.pharep.2017.01.002","volume":"69","author":"Bezerra","year":"2017","journal-title":"Pharmacol. Rep."},{"key":"D1FO01079D\/cit16","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1124\/jpet.105.085415","volume":"314","author":"Rice","year":"2005","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"D1FO01079D\/cit17","doi-asserted-by":"crossref","first-page":"14950","DOI":"10.3390\/molecules200814950","volume":"20","author":"Ara\u00fajo","year":"2015","journal-title":"Molecules"},{"key":"D1FO01079D\/cit18","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1590\/S1415-47572010005000103","volume":"34","author":"Magnani","year":"2011","journal-title":"Genet. Mol. Biol."},{"key":"D1FO01079D\/cit19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2018.00607","volume":"9","author":"Carvalho-Galv\u00e3o","year":"2018","journal-title":"Front. Physiol."},{"key":"D1FO01079D\/cit20","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.bcp.2017.06.045","volume":"139","author":"Paix\u00e3o Vieira","year":"2017","journal-title":"Biochem. Pharmacol."},{"key":"D1FO01079D\/cit21","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s12038-011-9097-y","volume":"36","author":"Dornas","year":"2011","journal-title":"J. Biosci."},{"key":"D1FO01079D\/cit22","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1097\/00005344-199312000-00019","volume":"22","author":"Bazil","year":"1993","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"D1FO01079D\/cit23","doi-asserted-by":"crossref","first-page":"381","DOI":"10.33549\/physiolres.932189","volume":"60","author":"Pint\u00e9rov\u00e1","year":"2011","journal-title":"Physiol. Res."},{"key":"D1FO01079D\/cit24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.17306\/J.AFS.2014.1.9","volume":"13","author":"Suliburska","year":"2014","journal-title":"Acta Sci. Pol., Technol. Aliment."},{"key":"D1FO01079D\/cit25","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.autneu.2010.07.025","volume":"159","author":"Botelho-Ono","year":"2011","journal-title":"Auton. Neurosci."},{"key":"D1FO01079D\/cit26","first-page":"1168","volume":"295","author":"Braga","year":"2008","journal-title":"Am. J. Physiol."},{"key":"D1FO01079D\/cit27","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1042\/CS20180222","volume":"132","author":"Carvalho-Galv\u00e3o","year":"2018","journal-title":"Clin. Sci."},{"key":"D1FO01079D\/cit28","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/01.hjh.0000198029.22472.d9","volume":"24","author":"S\u00e1nchez","year":"2006","journal-title":"J. Hypertens."},{"key":"D1FO01079D\/cit29","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jnutbio.2010.11.011","volume":"23","author":"Poudyal","year":"2012","journal-title":"J. Nutr. Biochem."},{"key":"D1FO01079D\/cit30","first-page":"1","volume-title":"Editora UFMG","volume":"1","author":"Caliari","year":"1997","unstructured":"M. V.Caliari ,  Princ\u00edpios de Morfometria Digital: KS 300 para iniciantes ,  Editora UFMG ,  1997 , vol.  1 , pp.  1\u2013149"},{"key":"D1FO01079D\/cit31","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1139\/y11-118","volume":"90","author":"Korolenko","year":"2012","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"D1FO01079D\/cit32","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s10517-014-2613-y","volume":"157","author":"Pisareva","year":"2014","journal-title":"Bull. Exp. Biol. Med."},{"key":"D1FO01079D\/cit33","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1080\/19390211.2016.1207005","volume":"14","author":"Mosikanon","year":"2017","journal-title":"J. Diet. Suppl."},{"key":"D1FO01079D\/cit34","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1159\/000082313","volume":"24","author":"Rodr\u00edguez-Iturbe","year":"2004","journal-title":"Am. J. Nephrol."},{"key":"D1FO01079D\/cit35","doi-asserted-by":"crossref","first-page":"859","DOI":"10.3892\/etm.2010.121","volume":"1","author":"Magnani","year":"2010","journal-title":"Exp. Ther. Med."},{"key":"D1FO01079D\/cit36","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1253\/circj.CJ-14-1013","volume":"79","author":"Sata","year":"2015","journal-title":"Circ. J."},{"key":"D1FO01079D\/cit37","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.autneu.2008.03.009","volume":"142","author":"Pickering","year":"2008","journal-title":"Auton. Neurosci."},{"key":"D1FO01079D\/cit38","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3389\/fphys.2016.00211","volume":"7","author":"Klippel","year":"2016","journal-title":"Front. Physiol."},{"key":"D1FO01079D\/cit39","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1089\/109662002760178159","volume":"5","author":"Babincova","year":"2002","journal-title":"J. Med. Food"},{"key":"D1FO01079D\/cit40","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3109\/09637486.2014.893286","volume":"65","author":"Carillon","year":"2014","journal-title":"Int. J. Food Sci. Nutr."},{"key":"D1FO01079D\/cit41","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1440-1681.2012.05679.x","volume":"39","author":"Guimaraes","year":"2012","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"D1FO01079D\/cit42","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0008-6363(98)00076-5","volume":"39","author":"Doggrell","year":"1998","journal-title":"Cardiovasc. Res."},{"key":"D1FO01079D\/cit43","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1291\/hypres.31.1465","volume":"31","author":"\u00c1lvarez","year":"2008","journal-title":"Hypertens. Res."},{"key":"D1FO01079D\/cit44","first-page":"3301","volume":"293","author":"Chen-Izu","year":"2007","journal-title":"Am. J. Physiol."},{"key":"D1FO01079D\/cit45","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/S1567-5769(02)00134-0","volume":"2","author":"Engstad","year":"2002","journal-title":"Int. Immunopharmacol."},{"key":"D1FO01079D\/cit46","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1128\/IAI.00086-09","volume":"77","author":"Huang","year":"2009","journal-title":"Infect. Immun."},{"key":"D1FO01079D\/cit47","first-page":"1002","volume":"83","author":"Akhapkina","year":"2018","journal-title":"Biochemistry"}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/FO\/D1FO01079D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:28:14Z","timestamp":1782883694000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/12\/18\/8552-8560\/728392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":47,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2021,9,20]]}},"URL":"https:\/\/doi.org\/10.1039\/d1fo01079d","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}