{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:26:23Z","timestamp":1783470383145,"version":"3.55.0"},"reference-count":77,"publisher":"Royal Society of Chemistry (RSC)","issue":"22","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"am","delay-in-days":638,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32101908"],"award-info":[{"award-number":["32101908"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["GK202003082"],"award-info":[{"award-number":["GK202003082"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010228","name":"Natural Science Foundation of Shaanxi Provincial Department of Education","doi-asserted-by":"publisher","award":["2020KW-031"],"award-info":[{"award-number":["2020KW-031"]}],"id":[{"id":"10.13039\/501100010228","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>Hypertension has become an increasing health concern given that it is a major risk for cardiovascular disease.<\/jats:p>","DOI":"10.1039\/d1fo02435c","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T22:21:01Z","timestamp":1633040461000},"page":"11121-11131","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Antihypertensive potential of fermented milk: the contribution of lactic acid bacteria proteolysis system and the resultant angiotensin-converting enzyme inhibitory peptide"],"prefix":"10.1039","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6808-1121","authenticated-orcid":false,"given":"Li","family":"Chen","sequence":"first","affiliation":[{"name":"College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianke","family":"Li","sequence":"additional","affiliation":[{"name":"College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guowei","family":"Shu","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1FO02435C\/cit1","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1097\/HJH.0000000000002021","volume":"37","author":"Egan","year":"2019","journal-title":"J. Hypertens."},{"key":"D1FO02435C\/cit2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1146\/annurev-food-022814-015520","volume":"6","author":"Aluko","year":"2015","journal-title":"Annu. Rev. Food Sci. Technol."},{"key":"D1FO02435C\/cit3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.tifs.2019.04.002","volume":"88","author":"Abdelhedi","year":"2019","journal-title":"Trends Food Sci. Technol."},{"key":"D1FO02435C\/cit4","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.maturitas.2018.06.016","volume":"115","author":"Ahtesh","year":"2018","journal-title":"Maturitas"},{"key":"D1FO02435C\/cit5","doi-asserted-by":"crossref","first-page":"104059","DOI":"10.1016\/j.jff.2020.104059","volume":"72","author":"Garcia-Burgos","year":"2020","journal-title":"J. Funct. Foods"},{"key":"D1FO02435C\/cit6","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3168\/jds.S0022-0302(95)76689-9","volume":"78","author":"Nakamura","year":"1995","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit7","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.3168\/jds.S0022-0302(95)76745-5","volume":"78","author":"Nakamura","year":"1995","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit8","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1021\/jf072671n","volume":"56","author":"Ohsawa","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"D1FO02435C\/cit9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2011.01.039","volume":"146","author":"Sadat-Mekmene","year":"2011","journal-title":"Int. J. Food Microbiol."},{"key":"D1FO02435C\/cit10","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/1541-4337.12455","volume":"18","author":"Venegas-Ortega","year":"2019","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"D1FO02435C\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-100596-5.00862-3","volume-title":"Reference Module in Food Science","author":"Ahtesh","year":"2021","unstructured":"F. B.Ahtesh ,  L.Stojanovska  and  V.Apostolopoulos ,  Proteolytic Systems of Lactic Acid Bacteria (LAB) , in  Reference Module in Food Science ,  2021 ,  10.1016\/B978-0-08-100596-5.00862-3"},{"key":"D1FO02435C\/cit12","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s00253-006-0427-1","volume":"71","author":"Savijoki","year":"2006","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"D1FO02435C\/cit13","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.3390\/ijms19041068","volume":"19","author":"Tian","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"D1FO02435C\/cit14","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/1541-4337.12459","volume":"18","author":"Zhang","year":"2019","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"D1FO02435C\/cit15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/1541-4337.12676","volume":"20","author":"Ji","year":"2020","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"D1FO02435C\/cit16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1134\/S002626171601015X","volume":"85","author":"Vukotic","year":"2016","journal-title":"Microbiology"},{"key":"D1FO02435C\/cit17","doi-asserted-by":"crossref","first-page":"6985","DOI":"10.1021\/acs.jafc.6b03379","volume":"64","author":"Guo","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"D1FO02435C\/cit18","doi-asserted-by":"crossref","first-page":"4592","DOI":"10.1128\/JB.181.15.4592-4597.1999","volume":"181","author":"Pederson","year":"1999","journal-title":"J. Bacteriol."},{"key":"D1FO02435C\/cit19","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1128\/jb.178.11.3059-3065.1996","volume":"178","author":"Gilbert","year":"1996","journal-title":"J. Bacteriol."},{"key":"D1FO02435C\/cit20","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/pro.5560060301","volume":"6","author":"Siezen","year":"1997","journal-title":"Protein Sci."},{"key":"D1FO02435C\/cit21","doi-asserted-by":"crossref","first-page":"4772","DOI":"10.1128\/AEM.66.11.4772-4778.2000","volume":"66","author":"Fernandez-Espla","year":"2000","journal-title":"Appl. Environ. Microbiol."},{"key":"D1FO02435C\/cit22","doi-asserted-by":"crossref","first-page":"3377","DOI":"10.1128\/AEM.69.6.3377-3384.2003","volume":"69","author":"Germond","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"D1FO02435C\/cit23","doi-asserted-by":"crossref","first-page":"961","DOI":"10.3168\/jds.2018-14899","volume":"102","author":"Guo","year":"2019","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit24","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.foodchem.2008.06.002","volume":"112","author":"Guo","year":"2009","journal-title":"Food Chem."},{"key":"D1FO02435C\/cit25","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/1541-4337.12457","volume":"18","author":"Li","year":"2019","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"D1FO02435C\/cit26","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.idairyj.2018.06.010","volume":"85","author":"Solieri","year":"2018","journal-title":"Int. Dairy J."},{"key":"D1FO02435C\/cit27","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.3390\/molecules23061317","volume":"23","author":"Shu","year":"2018","journal-title":"Molecules"},{"key":"D1FO02435C\/cit28","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1074\/jbc.270.4.1569","volume":"270","author":"Kunji","year":"1995","journal-title":"J. Biol. Chem."},{"key":"D1FO02435C\/cit29","doi-asserted-by":"crossref","first-page":"16671","DOI":"10.1021\/bi981712t","volume":"37","author":"Detmers","year":"1998","journal-title":"Biochemistry"},{"key":"D1FO02435C\/cit30","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1128\/AEM.64.4.1230-1236.1998","volume":"64","author":"Juillard","year":"1998","journal-title":"Appl. Environ. Microbiol."},{"key":"D1FO02435C\/cit31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1471-2164-11-15","volume":"11","author":"Liu","year":"2010","journal-title":"BMC Genomics"},{"key":"D1FO02435C\/cit32","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.idairyj.2006.12.001","volume":"17","author":"Kilpi","year":"2007","journal-title":"Int. Dairy J."},{"key":"D1FO02435C\/cit33","first-page":"e01319","volume":"86","author":"Huang","year":"2020","journal-title":"Appl. Environ. Microbiol."},{"key":"D1FO02435C\/cit34","doi-asserted-by":"crossref","first-page":"4706","DOI":"10.2174\/138161212802651670","volume":"18","author":"Marques","year":"2012","journal-title":"Curr. Pharm. Des."},{"key":"D1FO02435C\/cit35","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.tifs.2017.07.011","volume":"69","author":"Wu","year":"2017","journal-title":"Trends Food Sci. Technol."},{"key":"D1FO02435C\/cit36","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ejphar.2009.08.005","volume":"620","author":"Yamaguchi","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"D1FO02435C\/cit37","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00380-010-0096-y","volume":"26","author":"Hirota","year":"2011","journal-title":"Heart Vessels"},{"key":"D1FO02435C\/cit38","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.lfs.2010.11.001","volume":"88","author":"Ehlers","year":"2011","journal-title":"Life Sci."},{"key":"D1FO02435C\/cit39","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1089\/jmf.2012.2541","volume":"16","author":"Nakamura","year":"2013","journal-title":"J. Med. Food"},{"key":"D1FO02435C\/cit40","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.idairyj.2019.05.012","volume":"97","author":"Soleymanzadeh","year":"2019","journal-title":"Int. Dairy J."},{"key":"D1FO02435C\/cit41","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/bs.afnr.2019.04.001","volume":"89","author":"Ganguly","year":"2019","journal-title":"Adv. Food Nutr. Res."},{"key":"D1FO02435C\/cit42","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.idairyj.2007.09.006","volume":"18","author":"Quir\u00f3s","year":"2008","journal-title":"Int. Dairy J."},{"key":"D1FO02435C\/cit43","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jchromb.2005.10.036","volume":"830","author":"Van Platerink","year":"2006","journal-title":"J. Chromatogr. B: Anal. Technol. Biomed. Life Sci."},{"key":"D1FO02435C\/cit44","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3168\/jds.S0022-0302(96)76487-1","volume":"79","author":"Maeno","year":"1996","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit45","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1016\/j.peptides.2008.08.011","volume":"29","author":"van der Pijl","year":"2008","journal-title":"Peptides"},{"key":"D1FO02435C\/cit46","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/jn\/137.4.953","volume":"137","author":"Foltz","year":"2007","journal-title":"J. Nutr."},{"key":"D1FO02435C\/cit47","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1038\/ejcn.2010.3","volume":"64","author":"Jauhiainen","year":"2010","journal-title":"Eur. J. Clin. Nutr."},{"key":"D1FO02435C\/cit48","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1016\/j.amjhyper.2005.06.006","volume":"18","author":"Jauhiainen","year":"2005","journal-title":"Am. J. Hypertens."},{"key":"D1FO02435C\/cit49","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1093\/ajcn\/77.2.326","volume":"77","author":"Seppo","year":"2003","journal-title":"Am. J. Clin. Nutr."},{"key":"D1FO02435C\/cit50","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1271\/bbb.58.776","volume":"58","author":"Yamamoto","year":"1994","journal-title":"Biosci., Biotechnol., Biochem."},{"key":"D1FO02435C\/cit51","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/(SICI)1521-3803(19990601)43:3<159::AID-FOOD159>3.0.CO;2-R","volume":"43","author":"Yamamoto","year":"1999","journal-title":"Nahrung"},{"key":"D1FO02435C\/cit52","first-page":"124","volume":"57","author":"Seppo","year":"2002","journal-title":"Milchwissenschaft"},{"key":"D1FO02435C\/cit53","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.idairyj.2006.07.004","volume":"17","author":"Chen","year":"2007","journal-title":"Int. Dairy J."},{"key":"D1FO02435C\/cit54","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.idairyj.2010.01.007","volume":"20","author":"Pan","year":"2010","journal-title":"Int. Dairy J."},{"key":"D1FO02435C\/cit55","doi-asserted-by":"crossref","first-page":"5536","DOI":"10.3168\/jds.2011-5186","volume":"95","author":"Rodriguez-Figueroa","year":"2012","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit56","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.lwt.2012.09.017","volume":"51","author":"Nejati","year":"2013","journal-title":"LWT \u2013 Food Sci. Technol."},{"key":"D1FO02435C\/cit57","doi-asserted-by":"crossref","first-page":"6680","DOI":"10.3168\/jds.2014-7962","volume":"97","author":"Chen","year":"2014","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit58","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3168\/jds.2018-14602","volume":"102","author":"Zhou","year":"2019","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit59","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.fm.2014.03.005","volume":"42","author":"Chaves-Lopez","year":"2014","journal-title":"Food Microbiol."},{"key":"D1FO02435C\/cit60","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.fm.2015.05.012","volume":"51","author":"Solieri","year":"2015","journal-title":"Food Microbiol."},{"key":"D1FO02435C\/cit61","doi-asserted-by":"crossref","first-page":"7333","DOI":"10.1021\/acs.jafc.5b01649","volume":"63","author":"Liu","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"D1FO02435C\/cit62","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/1471-0307.12479","volume":"71","author":"Ahtesh","year":"2017","journal-title":"Int. J. Dairy Technol."},{"key":"D1FO02435C\/cit63","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/1471-0307.12425","volume":"71","author":"Ahtesh","year":"2017","journal-title":"Int. J. Dairy Technol."},{"key":"D1FO02435C\/cit64","doi-asserted-by":"crossref","first-page":"900","DOI":"10.3168\/jds.2017-13400","volume":"101","author":"Ayyash","year":"2018","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit65","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.fbio.2018.03.004","volume":"23","author":"Solanki","year":"2018","journal-title":"Food Biosci."},{"key":"D1FO02435C\/cit66","doi-asserted-by":"crossref","first-page":"5913","DOI":"10.3168\/jds.2018-15901","volume":"102","author":"Wu","year":"2019","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit67","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1007\/s10068-018-0423-0","volume":"27","author":"Daliri","year":"2018","journal-title":"Food Sci. Biotechnol."},{"key":"D1FO02435C\/cit68","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.lwt.2018.02.002","volume":"91","author":"Chen","year":"2018","journal-title":"LWT \u2013 Food Sci. Technol."},{"key":"D1FO02435C\/cit69","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s12602-018-9410-2","volume":"11","author":"Shu","year":"2019","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"D1FO02435C\/cit70","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.3168\/jds.2019-17165","volume":"103","author":"Li","year":"2020","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit71","doi-asserted-by":"crossref","first-page":"4919","DOI":"10.3168\/jds.2019-17594","volume":"103","author":"Xia","year":"2020","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit72","doi-asserted-by":"crossref","first-page":"108318","DOI":"10.1016\/j.jnutbio.2019.108318","volume":"77","author":"Silva","year":"2020","journal-title":"J. Nutr. Biochem."},{"key":"D1FO02435C\/cit73","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.foodchem.2019.01.010","volume":"282","author":"Amorim","year":"2019","journal-title":"Food Chem."},{"key":"D1FO02435C\/cit74","doi-asserted-by":"crossref","first-page":"345","DOI":"10.14202\/vetworld.2020.345-353","volume":"13","author":"Rubak","year":"2020","journal-title":"Vet. World"},{"key":"D1FO02435C\/cit75","doi-asserted-by":"crossref","first-page":"5805","DOI":"10.3168\/jds.2019-17976","volume":"103","author":"Adams","year":"2020","journal-title":"J. Dairy Sci."},{"key":"D1FO02435C\/cit76","doi-asserted-by":"crossref","first-page":"127482","DOI":"10.1016\/j.foodchem.2020.127482","volume":"333","author":"Cavalheiro","year":"2020","journal-title":"Food Chem."},{"key":"D1FO02435C\/cit77","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3390\/foods10010017","volume":"10","author":"Begunova","year":"2021","journal-title":"Foods"}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/FO\/D1FO02435C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:03:57Z","timestamp":1783015437000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/12\/22\/11121-11131\/728711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":77,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2021,11,15]]}},"URL":"https:\/\/doi.org\/10.1039\/d1fo02435c","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}