{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:00:48Z","timestamp":1790308848984,"version":"4.1.0"},"reference-count":51,"publisher":"Royal Society of Chemistry (RSC)","issue":"24","license":[{"start":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T00:00:00Z","timestamp":1643932800000},"content-version":"vor","delay-in-days":399,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81874264"],"award-info":[{"award-number":["81874264"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    The present study provided the first\n                    <jats:italic>in vivo<\/jats:italic>\n                    evidence that Ses pretreatment potentially represents a novel and pragmatic therapeutic strategy to protect the cardiovascular system from damage\n                    <jats:italic>via<\/jats:italic>\n                    its anti-ferroptosis activity.\n                  <\/jats:p>","DOI":"10.1039\/d1fo02913d","type":"journal-article","created":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T21:01:07Z","timestamp":1636405267000},"page":"12671-12682","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Sesamin attenuates PM\n                    <sub>2.5<\/sub>\n                    -induced cardiovascular injury by inhibiting ferroptosis in rats"],"prefix":"10.1039","volume":"12","author":[{"given":"Jing-yi","family":"Ren","sequence":"first","affiliation":[{"name":"Department of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-wen","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Public Health, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-qi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Public Health, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-liang","family":"Deng","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-ting","family":"Sun","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-ao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Public Health, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-hao","family":"Guo","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Public Health, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan-ting","family":"Pei","sequence":"additional","affiliation":[{"name":"Undergraduate of College of Public Health, Hebei Medical University, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-qiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-ge","family":"Chen","sequence":"additional","affiliation":[{"name":"Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3926-2644","authenticated-orcid":false,"given":"Yu-xia","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1FO02913D\/cit1\/1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ejim.2013.04.001","volume":"24","author":"Martinelli","year":"2013","journal-title":"Eur. J. Intern. Med."},{"key":"D1FO02913D\/cit2\/1","doi-asserted-by":"crossref","first-page":"9416","DOI":"10.1021\/acs.est.6b02533","volume":"50","author":"Archer-Nicholls","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"D1FO02913D\/cit3\/1","doi-asserted-by":"crossref","first-page":"112071","DOI":"10.1016\/j.ecoenv.2021.112071","volume":"214","author":"Liu","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"D1FO02913D\/cit4\/1","doi-asserted-by":"crossref","first-page":"6396","DOI":"10.21037\/jtd-19-crh-aq-004","volume":"12","author":"Yin","year":"2020","journal-title":"J. Thorac. Dis."},{"key":"D1FO02913D\/cit5\/1","doi-asserted-by":"crossref","first-page":"47574","DOI":"10.1007\/s11356-021-13965-9","volume":"28","author":"Zeng","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"D1FO02913D\/cit6\/1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1136\/oemed-2014-102696","volume":"72","author":"Kajbafzadeh","year":"2015","journal-title":"Occup. Environ. Med."},{"key":"D1FO02913D\/cit7\/1","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.18632\/oncotarget.23347","volume":"9","author":"Guan","year":"2018","journal-title":"Oncotarget"},{"key":"D1FO02913D\/cit8\/1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.envres.2019.01.040","volume":"172","author":"Yang","year":"2019","journal-title":"Environ. Res."},{"key":"D1FO02913D\/cit9\/1","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/ije\/dyaa235","volume":"50","author":"Woo","year":"2021","journal-title":"Int. J. Epidemiol."},{"key":"D1FO02913D\/cit10\/1","doi-asserted-by":"crossref","first-page":"e002742","DOI":"10.1161\/JAHA.115.002742","volume":"5","author":"Li","year":"2016","journal-title":"J. Am. Heart Assoc."},{"key":"D1FO02913D\/cit11\/1","doi-asserted-by":"crossref","first-page":"22153","DOI":"10.1007\/s11356-018-2292-8","volume":"25","author":"Zeng","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"D1FO02913D\/cit12\/1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.7150\/ijbs.36073","volume":"16","author":"Long","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"D1FO02913D\/cit13\/1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1476-069X-12-40","volume":"12","author":"Weichenthal","year":"2013","journal-title":"Environ. Health"},{"key":"D1FO02913D\/cit14\/1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.freeradbiomed.2020.11.015","volume":"163","author":"Liu","year":"2021","journal-title":"Free Radicals Biol. Med."},{"key":"D1FO02913D\/cit15\/1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.phymed.2018.09.206","volume":"52","author":"Tian","year":"2019","journal-title":"Phytomedicine"},{"key":"D1FO02913D\/cit16\/1","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"D1FO02913D\/cit17\/1","doi-asserted-by":"crossref","first-page":"112937","DOI":"10.1016\/j.envpol.2019.07.105","volume":"254","author":"Wang","year":"2019","journal-title":"Environ. Pollut."},{"key":"D1FO02913D\/cit18\/1","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1073\/pnas.1821022116","volume":"116","author":"Fang","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D1FO02913D\/cit19\/1","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1289\/ehp.10578","volume":"116","author":"Romieu","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"D1FO02913D\/cit20\/1","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1016\/j.jacc.2018.12.093","volume":"73","author":"Lin","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"D1FO02913D\/cit21\/1","doi-asserted-by":"crossref","first-page":"109598","DOI":"10.1016\/j.ecoenv.2019.109598","volume":"184","author":"Jiang","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"D1FO02913D\/cit22\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408398.2021.1881438","volume":"5","author":"Majdalawieh","year":"2021","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D1FO02913D\/cit23\/1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.chemosphere.2017.01.042","volume":"173","author":"Du","year":"2017","journal-title":"Chemosphere"},{"key":"D1FO02913D\/cit24\/1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12940-021-00718-x","volume":"20","author":"Yao","year":"2021","journal-title":"Environ. Health"},{"key":"D1FO02913D\/cit25\/1","doi-asserted-by":"crossref","first-page":"101161","DOI":"10.1016\/j.redox.2019.101161","volume":"22","author":"Yue","year":"2019","journal-title":"Redox Biol."},{"key":"D1FO02913D\/cit26\/1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.freeradbiomed.2020.10.307","volume":"162","author":"Tang","year":"2021","journal-title":"Free Radicals Biol. Med."},{"key":"D1FO02913D\/cit27\/1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jhazmat.2015.02.006","volume":"287","author":"Li","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"D1FO02913D\/cit28\/1","doi-asserted-by":"crossref","first-page":"6403","DOI":"10.1111\/jcmm.16620","volume":"25","author":"Chen","year":"2021","journal-title":"J. Cell. Mol. Med."},{"key":"D1FO02913D\/cit29\/1","first-page":"115","author":"Cao","year":"2020","journal-title":"Basic Res. Cardiol."},{"key":"D1FO02913D\/cit30\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12903-020-01356-4","volume":"21","author":"Wojtkowska","year":"2021","journal-title":"BMC Oral Health"},{"key":"D1FO02913D\/cit31\/1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1021\/acs.jafc.6b04603","volume":"65","author":"Wang","year":"2017","journal-title":"J. Agric. Food Chem."},{"key":"D1FO02913D\/cit32\/1","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1177\/0192623309339503","volume":"37","author":"Golomb","year":"2009","journal-title":"Toxicol. Pathol."},{"key":"D1FO02913D\/cit33\/1","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1007\/s00394-012-0482-6","volume":"52","author":"Hemshekhar","year":"2013","journal-title":"Eur. J. Nutr."},{"key":"D1FO02913D\/cit34\/1","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.jsps.2020.08.018","volume":"28","author":"Dalibalta","year":"2020","journal-title":"Saudi Pharm. J."},{"key":"D1FO02913D\/cit35\/1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ejphar.2009.08.023","volume":"620","author":"Kong","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"D1FO02913D\/cit36\/1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1089\/jmf.2014.0138","volume":"18","author":"Narasimhulu","year":"2015","journal-title":"J. Med. Food"},{"key":"D1FO02913D\/cit37\/1","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/nature06797","volume":"451","author":"Mackman","year":"2008","journal-title":"Nature"},{"key":"D1FO02913D\/cit38\/1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1291\/hypres.24.735","volume":"24","author":"Noguchi","year":"2001","journal-title":"Hypertens. Res."},{"key":"D1FO02913D\/cit39\/1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ecoenv.2016.01.030","volume":"128","author":"Feng","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"D1FO02913D\/cit40\/1","first-page":"8613523","volume":"2019","author":"Huang","year":"2019","journal-title":"Mediators Inflammation"},{"key":"D1FO02913D\/cit41\/1","doi-asserted-by":"crossref","first-page":"685775","DOI":"10.3389\/fcell.2021.685775","volume":"9","author":"Li","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"D1FO02913D\/cit42\/1","doi-asserted-by":"crossref","first-page":"110108","DOI":"10.1016\/j.biopha.2020.110108","volume":"127","author":"Sun","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"D1FO02913D\/cit43\/1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/cdd.2015.158","volume":"23","author":"Xie","year":"2016","journal-title":"Cell Death Differ."},{"key":"D1FO02913D\/cit44\/1","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.freeradbiomed.2015.03.037","volume":"84","author":"Tripathi","year":"2015","journal-title":"Free Radicals Biol. Med."},{"key":"D1FO02913D\/cit45\/1","doi-asserted-by":"crossref","first-page":"424767","DOI":"10.1155\/2014\/424767","volume":"2014","author":"Calla-Choque","year":"2014","journal-title":"BioMed Res. Int."},{"key":"D1FO02913D\/cit46\/1","doi-asserted-by":"crossref","first-page":"105466","DOI":"10.1016\/j.phrs.2021.105466","volume":"166","author":"Li","year":"2021","journal-title":"Pharmacol. Res."},{"key":"D1FO02913D\/cit47\/1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.14336\/AD.2020.0323","volume":"12","author":"Ju","year":"2021","journal-title":"Aging Dis."},{"key":"D1FO02913D\/cit48\/1","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1007\/s11064-019-02747-y","volume":"44","author":"Tsatsanis","year":"2019","journal-title":"Neurochem. Res."},{"key":"D1FO02913D\/cit49\/1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1084\/jem.20140857","volume":"212","author":"Matsushita","year":"2015","journal-title":"J. Exp. Med."},{"key":"D1FO02913D\/cit50\/1","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.3390\/ijms20102493","volume":"20","author":"Chen","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"D1FO02913D\/cit51\/1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/cdd.2015.158","volume":"23","author":"Xie","year":"2016","journal-title":"Cell Death Differ."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/FO\/D1FO02913D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:15:21Z","timestamp":1782882921000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/12\/24\/12671-12682\/728803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":51,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2021,12,13]]}},"URL":"https:\/\/doi.org\/10.1039\/d1fo02913d","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}