{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:17:01Z","timestamp":1790745421061,"version":"4.1.0"},"reference-count":49,"publisher":"Royal Society of Chemistry (RSC)","issue":"2","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"am","delay-in-days":334,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32101872"],"award-info":[{"award-number":["32101872"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871750"],"award-info":[{"award-number":["31871750"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20181416"],"award-info":[{"award-number":["BK20181416"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20200837"],"award-info":[{"award-number":["BK20200837"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007540","name":"Jiangsu Agricultural Science and Technology Innovation Fund","doi-asserted-by":"publisher","award":["CX(21)3041"],"award-info":[{"award-number":["CX(21)3041"]}],"id":[{"id":"10.13039\/100007540","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>We prepared a detoxified rapeseed protein isolate (RPI) by phytase\/ethanol treatment based on alkaline extraction and acidic precipitation.<\/jats:p>","DOI":"10.1039\/d1fo03217h","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T06:43:30Z","timestamp":1638341010000},"page":"664-674","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Removal of anti-nutritional factors of rapeseed protein isolate (RPI) and toxicity assessment of RPI"],"prefix":"10.1039","volume":"13","author":[{"given":"Zheng","family":"Xiong","sequence":"first","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoyao","family":"Fu","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yao","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3341-9786","authenticated-orcid":false,"given":"Rong","family":"He","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingrong","family":"Ju","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1821-4843","authenticated-orcid":false,"given":"Zhigao","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D1FO03217H\/cit1\/1","doi-asserted-by":"crossref","first-page":"3607","DOI":"10.1021\/acs.jafc.0c00128","volume":"68","author":"Wang","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"D1FO03217H\/cit2\/1","doi-asserted-by":"crossref","first-page":"D407","DOI":"10.1051\/ocl\/2016028","volume":"23","author":"Wanasundara","year":"2016","journal-title":"OCL: Oilseeds Fats, Crops Lipids"},{"key":"D1FO03217H\/cit3\/1","first-page":"1","author":"Chmielewska","year":"2020","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D1FO03217H\/cit4\/1","doi-asserted-by":"crossref","first-page":"7903","DOI":"10.1021\/jf5023803","volume":"62","author":"Das Purkayastha","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"D1FO03217H\/cit5\/1","first-page":"126","volume":"25","author":"Li","year":"2008","journal-title":"J. Fruit Sci."},{"key":"D1FO03217H\/cit6\/1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0377-8401(94)90031-0","volume":"45","author":"Liu","year":"1994","journal-title":"Anim. Feed Sci. Technol."},{"key":"D1FO03217H\/cit7\/1","doi-asserted-by":"crossref","first-page":"D105","DOI":"10.1051\/ocl\/2013041","volume":"21","author":"Adem","year":"2014","journal-title":"OCL"},{"key":"D1FO03217H\/cit8\/1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0377-8401(94)00740-Z","volume":"53","author":"Jensen","year":"1995","journal-title":"Anim. Feed Sci. Technol."},{"key":"D1FO03217H\/cit9\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jsfa.2740610102","volume":"61","author":"\u017byla","year":"1993","journal-title":"J. Sci. Food Agric."},{"key":"D1FO03217H\/cit11\/1","first-page":"1","author":"Helrich","year":"1990","journal-title":"Assoc. Off. Anal. Chem."},{"key":"D1FO03217H\/cit12\/1","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1021\/ac60032a019","volume":"21","author":"Viles Jr.","year":"1949","journal-title":"Anal. Chem."},{"key":"D1FO03217H\/cit13\/1","doi-asserted-by":"crossref","first-page":"7552","DOI":"10.1021\/jf402174f","volume":"61","author":"Zhou","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"D1FO03217H\/cit14\/1","doi-asserted-by":"crossref","first-page":"738","DOI":"10.5740\/jaoacint.16-0029","volume":"99","author":"McKie","year":"2016","journal-title":"J. AOAC Int."},{"key":"D1FO03217H\/cit15\/1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jep.2017.03.032","volume":"203","author":"Zhang","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"D1FO03217H\/cit16\/1","volume-title":"Test Guideline","volume":"423","author":"T. N. OECD","year":"2001","unstructured":"T. N. OECD ,  Acute Oral Toxicity: Acute Toxic Class Method , in  Test Guideline ,  2001 , vol.  423"},{"key":"D1FO03217H\/cit17\/1","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.procbio.2007.07.009","volume":"42","author":"Chabanon","year":"2007","journal-title":"Process Biochem."},{"key":"D1FO03217H\/cit18\/1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1159\/000176266","volume":"23","author":"Shah","year":"1979","journal-title":"Nutr. Metab."},{"key":"D1FO03217H\/cit19\/1","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1021\/jf60206a034","volume":"24","author":"O'Dell","year":"1976","journal-title":"J. Agric. Food Chem."},{"key":"D1FO03217H\/cit20\/1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/10408398009527293","volume":"13","author":"Cheryan","year":"1980","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D1FO03217H\/cit21\/1","first-page":"291","volume-title":"Removal of glucosinolates and other antinutrients from canola and rapeseed by methanol\/ammonia processing","author":"Shahidi","year":"1990","unstructured":"F.Shahidi  and  M.Naczk ,  Removal of glucosinolates and other antinutrients from canola and rapeseed by methanol\/ammonia processing ,  Springer ,  Boston. MA ,  1990 ,  291\u2013306"},{"key":"D1FO03217H\/cit22\/1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jspr.2009.12.001","volume":"46","author":"Morra","year":"2010","journal-title":"J. Stored Prod. Res."},{"key":"D1FO03217H\/cit23\/1","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/jn\/109.7.1129","volume":"109","author":"Papas","year":"1979","journal-title":"J. Nutr."},{"key":"D1FO03217H\/cit24\/1","first-page":"27","volume":"343","author":"Bourdon","year":"1981","journal-title":"Revue de l'Aliment. Anim."},{"key":"D1FO03217H\/cit25\/1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0308-8146(89)90026-5","volume":"31","author":"Naczk","year":"1989","journal-title":"Food Chem."},{"key":"D1FO03217H\/cit26\/1","first-page":"124","volume":"23","author":"Bate-Smith","year":"1954","journal-title":"Food"},{"key":"D1FO03217H\/cit27\/1","volume-title":"Report of the Commission on Enzymes of the International Union of Biochemistry","author":"I. U. o. B. C. o. Enzymes","year":"1964","unstructured":"I. U. o. B. C. o. Enzymes M.Florkin  and  E. H.Stotz ,  Report of the Commission on Enzymes of the International Union of Biochemistry ,  Elsevier ,  1964"},{"key":"D1FO03217H\/cit28\/1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1079\/095442200108729098","volume":"13","author":"Selle","year":"2000","journal-title":"Nutr. Res. Rev."},{"key":"D1FO03217H\/cit29\/1","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1002\/jsfa.8087","volume":"97","author":"Rodrigues","year":"2017","journal-title":"J. Sci. Food Agric."},{"key":"D1FO03217H\/cit30\/1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1021\/jf9806964","volume":"47","author":"Wang","year":"1999","journal-title":"J. Agric. Food Chem."},{"key":"D1FO03217H\/cit31\/1","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1021\/jf011202x","volume":"50","author":"van Koningsveld","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"D1FO03217H\/cit32\/1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.foodhyd.2016.01.018","volume":"57","author":"Lambrecht","year":"2016","journal-title":"Food Hydrocolloids"},{"key":"D1FO03217H\/cit33\/1","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1098\/rstb.2004.1500","volume":"359","author":"Nick Pace","year":"2004","journal-title":"Philos. Trans. R. Soc., B"},{"key":"D1FO03217H\/cit34\/1","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1016\/j.fct.2009.07.029","volume":"47","author":"Mejia","year":"2009","journal-title":"Food Chem. Toxicol."},{"key":"D1FO03217H\/cit35\/1","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1021\/ie50391a011","volume":"34","author":"Smith","year":"1942","journal-title":"Ind. Eng. Chem."},{"key":"D1FO03217H\/cit36\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0315-5463(75)73769-0","volume":"8","author":"Kozlowska","year":"1975","journal-title":"Can. Inst. Food Sci. Technol. J."},{"key":"D1FO03217H\/cit37\/1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jep.2007.09.022","volume":"115","author":"Tan","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"D1FO03217H\/cit38\/1","first-page":"76","volume":"3","author":"Vahalia","year":"2011","journal-title":"Recent Res. Sci. Technol."},{"key":"D1FO03217H\/cit39\/1","first-page":"37","volume":"2","author":"Etim","year":"2014","journal-title":"Agric. Sci."},{"key":"D1FO03217H\/cit40\/1","doi-asserted-by":"crossref","DOI":"10.1201\/9781420080124","volume-title":"Animal clinical chemistry: a practical handbook for toxicologists and biomedical researchers","author":"Evans","year":"2009","unstructured":"G. O.Evans ,  Animal clinical chemistry: a practical handbook for toxicologists and biomedical researchers ,  CRC Press ,  2009"},{"key":"D1FO03217H\/cit41\/1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.jep.2015.10.015","volume":"175","author":"Raina","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"D1FO03217H\/cit42\/1","first-page":"489","volume":"12","author":"Hayelom","year":"2012","journal-title":"Afr. Health Sci."},{"key":"D1FO03217H\/cit43\/1","first-page":"260","volume":"9","author":"Ou\u00e9draogoa","year":"2012","journal-title":"Afr. J. Tradit., Complementary Altern. Med."},{"key":"D1FO03217H\/cit44\/1","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/nbt.1623","volume":"28","author":"Vaidya","year":"2010","journal-title":"Nat. Biotechnol."},{"key":"D1FO03217H\/cit45\/1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1677\/joe.1.06137","volume":"189","author":"Klecha","year":"2006","journal-title":"J. Endocrinol."},{"key":"D1FO03217H\/cit46\/1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1079\/BJN19930125","volume":"70","author":"Rabot","year":"1993","journal-title":"Br. J. Nutr."},{"key":"D1FO03217H\/cit47\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.anifeedsci.2006.03.003","volume":"132","author":"Tripathi","year":"2007","journal-title":"Anim. Feed Sci. Technol."},{"key":"D1FO03217H\/cit48\/1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jep.2007.02.011","volume":"112","author":"Mukinda","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"D1FO03217H\/cit49\/1","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00216-011-4797-6","volume":"400","author":"Han","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"key":"D1FO03217H\/cit50\/1","first-page":"53","volume":"74","author":"Adedapo","year":"2004","journal-title":"Vet. Arh."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/FO\/D1FO03217H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:40:09Z","timestamp":1782967209000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/13\/2\/664-674\/728870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,1,24]]}},"URL":"https:\/\/doi.org\/10.1039\/d1fo03217h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}