{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:42:38Z","timestamp":1789065758032,"version":"build-2803163510"},"reference-count":53,"publisher":"Royal Society of Chemistry (RSC)","issue":"15","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"am","delay-in-days":529,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012590","name":"Opening Project of Shanghai Key Laboratory of New Drug Design","doi-asserted-by":"publisher","award":["17DZ2271000"],"award-info":[{"award-number":["17DZ2271000"]}],"id":[{"id":"10.13039\/501100012590","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973285"],"award-info":[{"award-number":["81973285"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019051","name":"State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University","doi-asserted-by":"publisher","award":["2019-KF-007"],"award-info":[{"award-number":["2019-KF-007"]}],"id":[{"id":"10.13039\/501100019051","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    Integrating tissue lipidomics, network pharmacology and molecular docking to explore the anti-gout mechanism of anthocyanins from\n                    <jats:italic>Lycium ruthenicum<\/jats:italic>\n                    Murr.\n                  <\/jats:p>","DOI":"10.1039\/d1fo04377c","type":"journal-article","created":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T02:01:18Z","timestamp":1686621678000},"page":"7011-7023","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Tissue lipidomics, network pharmacology, and molecular docking to explore the therapeutic mechanism of anthocyanins from\n                    <i>Lycium ruthenicum<\/i>\n                    Murr. against gouty arthritis"],"prefix":"10.1039","volume":"14","author":[{"given":"Li","family":"Li","sequence":"first","affiliation":[{"name":"School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiangqiang","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiqin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Yi","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyu","family":"Tang","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4836-9881","authenticated-orcid":false,"given":"Ping","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4745-2632","authenticated-orcid":false,"given":"Hongyang","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China"},{"name":"Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D1FO04377C\/cit1\/1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.foodchem.2010.11.052","volume":"126","author":"Zheng","year":"2011","journal-title":"Food Chem."},{"key":"D1FO04377C\/cit2\/1","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1021\/acs.jafc.8b06402","volume":"67","author":"Chen","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"D1FO04377C\/cit3\/1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.foodchem.2017.08.026","volume":"240","author":"Wang","year":"2018","journal-title":"Food Chem."},{"key":"D1FO04377C\/cit4\/1","doi-asserted-by":"crossref","first-page":"109334","DOI":"10.1016\/j.lwt.2020.109334","volume":"126","author":"Liu","year":"2020","journal-title":"LWT\u2013Food Sci. Technol."},{"key":"D1FO04377C\/cit5\/1","doi-asserted-by":"crossref","first-page":"4947","DOI":"10.1039\/C5AY00612K","volume":"7","author":"Jin","year":"2015","journal-title":"Anal. Methods"},{"key":"D1FO04377C\/cit6\/1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.foodchem.2008.09.001","volume":"113","author":"Castaneda-Ovando","year":"2009","journal-title":"Food Chem."},{"key":"D1FO04377C\/cit7\/1","doi-asserted-by":"crossref","first-page":"108952","DOI":"10.1016\/j.foodres.2019.108952","volume":"130","author":"Peng","year":"2020","journal-title":"Food Res. Int."},{"key":"D1FO04377C\/cit8\/1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1186\/s12906-019-2664-8","volume":"19","author":"Thilavech","year":"2019","journal-title":"BMC Complementary Altern. Med."},{"key":"D1FO04377C\/cit9\/1","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3945\/jn.114.205674","volume":"145","author":"Li","year":"2015","journal-title":"J. Nutr."},{"key":"D1FO04377C\/cit10\/1","doi-asserted-by":"crossref","first-page":"47848","DOI":"10.1039\/C7RA09846D","volume":"7","author":"Yin","year":"2017","journal-title":"RSC Adv."},{"key":"D1FO04377C\/cit11\/1","doi-asserted-by":"crossref","first-page":"e0162089","DOI":"10.1371\/journal.pone.0162089","volume":"11","author":"Liu","year":"2016","journal-title":"PLoS One"},{"key":"D1FO04377C\/cit12\/1","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1039\/D0FO02382E","volume":"12","author":"Li","year":"2021","journal-title":"Food Funct."},{"key":"D1FO04377C\/cit13\/1","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.indcrop.2018.12.026","volume":"129","author":"Zhang","year":"2019","journal-title":"Ind. Crops Prod."},{"key":"D1FO04377C\/cit14\/1","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.semarthrit.2020.06.015","volume":"50","author":"Bodofsky","year":"2020","journal-title":"Semin. Arthritis Rheum."},{"key":"D1FO04377C\/cit15\/1","first-page":"3461572","volume":"2018","author":"Li","year":"2018","journal-title":"BioMed Res. Int."},{"key":"D1FO04377C\/cit16\/1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s13075-018-1600-5","volume":"20","author":"Zhang","year":"2018","journal-title":"Arthritis Res. Ther."},{"key":"D1FO04377C\/cit17\/1","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1007\/s10067-006-0527-4","volume":"26","author":"Chen","year":"2007","journal-title":"Clin. Rheumatol."},{"key":"D1FO04377C\/cit18\/1","first-page":"26S","volume":"137","author":"Martinon","year":"2007","journal-title":"Swiss Med. Wkly."},{"key":"D1FO04377C\/cit19\/1","doi-asserted-by":"crossref","first-page":"R176","DOI":"10.1186\/ar4365","volume":"15","author":"Allaeys","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"D1FO04377C\/cit20\/1","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1080\/01480545.2021.1894707","volume":"45","author":"Govindasami","year":"2022","journal-title":"Drug Chem. Toxicol."},{"key":"D1FO04377C\/cit21\/1","doi-asserted-by":"crossref","first-page":"650808","DOI":"10.3389\/fimmu.2021.650808","volume":"12","author":"Pare","year":"2021","journal-title":"Front. Immunol."},{"key":"D1FO04377C\/cit22\/1","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1002\/cjoc.201600810","volume":"35","author":"Chen","year":"2017","journal-title":"Chin. J. Chem."},{"key":"D1FO04377C\/cit23\/1","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.3389\/fphar.2019.01626","volume":"10","author":"Xiao","year":"2020","journal-title":"Front. Pharmacol."},{"key":"D1FO04377C\/cit24\/1","doi-asserted-by":"crossref","first-page":"153274","DOI":"10.1016\/j.phymed.2020.153274","volume":"77","author":"Li","year":"2020","journal-title":"Phytomedicine"},{"key":"D1FO04377C\/cit25\/1","doi-asserted-by":"crossref","first-page":"7608","DOI":"10.1021\/acs.analchem.8b01331","volume":"90","author":"Xuan","year":"2018","journal-title":"Anal. Chem."},{"key":"D1FO04377C\/cit26\/1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1021\/acs.jproteome.0c00584","volume":"20","author":"Tan","year":"2021","journal-title":"J. Proteome Res."},{"key":"D1FO04377C\/cit27\/1","doi-asserted-by":"crossref","first-page":"152918","DOI":"10.1016\/j.phymed.2019.152918","volume":"74","author":"Li","year":"2020","journal-title":"Phytomedicine"},{"key":"D1FO04377C\/cit28\/1","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.2147\/DDDT.S301679","volume":"15","author":"Ge","year":"2021","journal-title":"Drug Des., Dev. Ther."},{"key":"D1FO04377C\/cit29\/1","doi-asserted-by":"crossref","first-page":"973","DOI":"10.3389\/fphar.2018.00973","volume":"9","author":"Zhai","year":"2018","journal-title":"Front. Pharmacol."},{"key":"D1FO04377C\/cit30\/1","doi-asserted-by":"crossref","first-page":"122102","DOI":"10.1016\/j.jchromb.2020.122102","volume":"1146","author":"Huang","year":"2020","journal-title":"J. Chromatogr. B: Anal. Technol. Biomed. Life Sci."},{"key":"D1FO04377C\/cit31\/1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.2174\/157340911795677602","volume":"7","author":"Meng","year":"2011","journal-title":"Curr. Comput.-Aided Drug Des."},{"key":"D1FO04377C\/cit32\/1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.foodchem.2018.01.055","volume":"250","author":"Ongkowijoyo","year":"2018","journal-title":"Food Chem."},{"key":"D1FO04377C\/cit33\/1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jep.2016.06.008","volume":"191","author":"Shi","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"D1FO04377C\/cit34\/1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/0091-3057(88)90004-4","volume":"29","author":"Coderre","year":"1988","journal-title":"Pharmacol., Biochem. Behav."},{"key":"D1FO04377C\/cit35\/1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/978-1-4939-6996-8_14","volume":"1609","author":"Cajka","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"D1FO04377C\/cit36\/1","first-page":"5526778","volume":"2021","author":"Jin","year":"2021","journal-title":"Evidence-Based Complementary Altern. Med."},{"key":"D1FO04377C\/cit37\/1","doi-asserted-by":"crossref","first-page":"4714","DOI":"10.1039\/D1FO04386B","volume":"13","author":"Yan","year":"2022","journal-title":"Food Funct."},{"key":"D1FO04377C\/cit38\/1","first-page":"5570968","volume":"2021","author":"Fan","year":"2021","journal-title":"Evidence-Based Complementary Altern. Med."},{"key":"D1FO04377C\/cit39\/1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1042\/bj1760631","volume":"176","author":"Infante","year":"1978","journal-title":"Biochem. J."},{"key":"D1FO04377C\/cit40\/1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.bbalip.2004.12.008","volume":"1733","author":"Kent","year":"2005","journal-title":"Biochim. Biophys. Acta, Mol. Cell Biol. Lipids"},{"key":"D1FO04377C\/cit41\/1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s12906-021-03350-x","volume":"21","author":"Yang","year":"2021","journal-title":"BMC Complementary Med. Ther."},{"key":"D1FO04377C\/cit42\/1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.plipres.2005.12.003","volume":"45","author":"Anderson","year":"2006","journal-title":"Prog. Lipid Res."},{"key":"D1FO04377C\/cit43\/1","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1517\/13543780903321490","volume":"18","author":"Yong","year":"2009","journal-title":"Expert Opin. Invest. Drugs"},{"key":"D1FO04377C\/cit44\/1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ctrv.2003.07.007","volume":"30","author":"Vara","year":"2004","journal-title":"Cancer Treat. Rev."},{"key":"D1FO04377C\/cit45\/1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0163-7827(03)00051-1","volume":"43","author":"Coleman","year":"2004","journal-title":"Prog. Lipid Res."},{"key":"D1FO04377C\/cit46\/1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s11084-005-9001-6","volume":"36","author":"Rushdi","year":"2006","journal-title":"Origins Life Evol. Biospheres"},{"key":"D1FO04377C\/cit47\/1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1194\/jlr.M033837","volume":"54","author":"Han","year":"2013","journal-title":"J. Lipid Res."},{"key":"D1FO04377C\/cit48\/1","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1093\/rheumatology\/keab743","volume":"61","author":"Liu","year":"2022","journal-title":"Rheumatology"},{"key":"D1FO04377C\/cit49\/1","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s12944-016-0252-1","volume":"15","author":"Zhou","year":"2016","journal-title":"Lipids Health Dis."},{"key":"D1FO04377C\/cit50\/1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/nrm2335","volume":"9","author":"Wymann","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"D1FO04377C\/cit51\/1","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1016\/j.bbamem.2006.05.011","volume":"1758","author":"Gomez-Munoz","year":"2006","journal-title":"Biochim. Biophys. Acta, Biomembr."},{"key":"D1FO04377C\/cit52\/1","doi-asserted-by":"crossref","first-page":"e91769","DOI":"10.1371\/journal.pone.0091769","volume":"9","author":"Kosinska","year":"2014","journal-title":"PLoS One"},{"key":"D1FO04377C\/cit53\/1","first-page":"505","volume":"152","author":"Gerritsen","year":"1998","journal-title":"Am. J. Pathol."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/FO\/D1FO04377C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:03:03Z","timestamp":1783015383000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/14\/15\/7011-7023\/729144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":53,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2023,7,31]]}},"URL":"https:\/\/doi.org\/10.1039\/d1fo04377c","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}