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Chem."],"abstract":"<p>\n                    Unreported macrodiolides containing a 1\n                    <italic>Z<\/italic>\n                    ,5\n                    <italic>Z<\/italic>\n                    -diene fragment have been synthesized. Their hybrid molecules with C\n                    <sub>60<\/sub>\n                    \u00a0fullerene was found to significantly increase the cytotoxic effect (from 5 to 170 times) as compared to the initial macrodiolide.\n                  <\/p>","DOI":"10.1039\/d1ob00023c","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T06:22:08Z","timestamp":1612160528000},"page":"1847-1853","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Synthesis and cytotoxic activity of unsaturated macrolides and their hybrid molecules with a C\n                    <sub>60<\/sub>\n                    fullerene"],"prefix":"10.1039","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2115-8304","authenticated-orcid":false,"given":"Airat R.","family":"Tuktarov","sequence":"first","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliya L.","family":"Khuzina","sequence":"additional","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zarema R.","family":"Sadretdinova","sequence":"additional","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elina Kh.","family":"Makarova","sequence":"additional","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilya U.","family":"Dzhemileva","sequence":"additional","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir A.","family":"D'yakonov","sequence":"additional","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usein M.","family":"Dzhemilev","sequence":"additional","affiliation":[{"name":"Institute of Petrochemistry and Catalysis of RAS (IPC RAS)"},{"name":"450075 Ufa"},{"name":"Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1OB00023C-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1021\/ol050618j","volume":"7","author":"Achard","year":"2005","journal-title":"Org. 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