{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:14:43Z","timestamp":1790342083812,"version":"4.1.0"},"reference-count":33,"publisher":"Royal Society of Chemistry (RSC)","issue":"42","license":[{"start":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:00:00Z","timestamp":1627603200000},"content-version":"vor","delay-in-days":210,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2017YFC1104602"],"award-info":[{"award-number":["2017YFC1104602"]}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<p>Therapeutic contact lenses fabricated by polysaccharides multilayer surface modification, shows \u201ckill-release\u201d antibacterial performance, can serve as an effective treatment for bacterial keratitis.<\/p>","DOI":"10.1039\/d1ra02472h","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T06:23:45Z","timestamp":1627626225000},"page":"26160-26167","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["\u201cKill-release\u201d antibacterial polysaccharides multilayer coating based therapeutic contact lens for effective bacterial keratitis treatment"],"prefix":"10.1039","volume":"11","author":[{"given":"Rui","family":"Wang","sequence":"first","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duoduo","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyu","family":"Zou","sequence":"additional","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Bai","sequence":"additional","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chulei","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2870-6059","authenticated-orcid":false,"given":"Quankui","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Ophthalmology & Optometry"},{"name":"Eye Hospital"},{"name":"Wenzhou Medical University"},{"name":"Wenzhou 325027"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1RA02472H-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.ejps.2014.07.013","volume":"63","author":"Ustundag-Okur","year":"2014","journal-title":"Eur. J. Pharm. Sci."},{"key":"D1RA02472H-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"369094","DOI":"10.1155\/2013\/369094","volume":"2013","author":"Marquart","year":"2013","journal-title":"J. Ophthalmol."},{"key":"D1RA02472H-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3109\/09273948.2016.1139136","volume":"25","author":"Bharti","year":"2017","journal-title":"Ocul. Immunol. Inflamm."},{"key":"D1RA02472H-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijpharm.2014.06.007","volume":"472","author":"Morrison","year":"2014","journal-title":"Int. J. Pharm."},{"key":"D1RA02472H-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"TFOS37","DOI":"10.1167\/iovs.13-13215","volume":"54","author":"Jones","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"D1RA02472H-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3390\/ma12020261","volume":"12","author":"Musgrave","year":"2019","journal-title":"Materials"},{"key":"D1RA02472H-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1900368","DOI":"10.1002\/adhm.201900368","volume":"8","author":"Moreddu","year":"2019","journal-title":"Adv. Healthcare Mater."},{"key":"D1RA02472H-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1801390","DOI":"10.1002\/adhm.201801390","volume":"8","author":"Mutlu","year":"2019","journal-title":"Adv. Healthcare Mater."},{"key":"D1RA02472H-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.ijpharm.2019.05.031","volume":"565","author":"Ubani-Ukoma","year":"2019","journal-title":"Int. J. Pharm."},{"key":"D1RA02472H-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.1039\/C7NR09692E","volume":"10","author":"Xie","year":"2018","journal-title":"Nanoscale"},{"key":"D1RA02472H-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jconrel.2012.10.010","volume":"165","author":"Jung","year":"2013","journal-title":"J. Controlled Release"},{"key":"D1RA02472H-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jconrel.2010.07.119","volume":"148","author":"Kim","year":"2010","journal-title":"J. Controlled Release"},{"key":"D1RA02472H-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.actbio.2009.07.021","volume":"6","author":"Xu","year":"2010","journal-title":"Acta Biomater."},{"key":"D1RA02472H-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.actbio.2010.10.003","volume":"7","author":"Yanez","year":"2011","journal-title":"Acta Biomater."},{"key":"D1RA02472H-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9047","DOI":"10.2147\/IJN.S215802","volume":"14","author":"Han","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"D1RA02472H-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1126\/science.aaa2491","volume":"348","author":"Richardson","year":"2015","journal-title":"Science"},{"key":"D1RA02472H-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1039\/b700410a","volume":"9","author":"Ariga","year":"2007","journal-title":"Phys. Chem. Chem. Phys."},{"key":"D1RA02472H-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/00914037.2016.1190925","volume":"66","author":"Lin","year":"2017","journal-title":"Int. J. Polym. Mater. Polym. Biomater."},{"key":"D1RA02472H-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.colcom.2018.03.007","volume":"24","author":"Han","year":"2018","journal-title":"J. Colloid Interface Sci."},{"key":"D1RA02472H-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4017","DOI":"10.1016\/j.biomaterials.2010.01.092","volume":"31","author":"Lin","year":"2010","journal-title":"Biomaterials"},{"key":"D1RA02472H-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/j.1365-2958.2008.06416.x","volume":"70","author":"Unoson","year":"2008","journal-title":"Mol. Microbiol."},{"key":"D1RA02472H-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6971","DOI":"10.1021\/nn202451x","volume":"5","author":"Shaobin Liu","year":"2011","journal-title":"ACS Nano"},{"key":"D1RA02472H-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.colsurfb.2009.10.008","volume":"76","author":"Krishnaraj","year":"2010","journal-title":"Colloids Surf., B"},{"key":"D1RA02472H-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.progpolymsci.2006.06.001","volume":"31","author":"Rinaudo","year":"2006","journal-title":"Prog. Polym. Sci."},{"key":"D1RA02472H-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1080\/17460441.2017.1290603","volume":"12","author":"Calamak","year":"2017","journal-title":"Expert Opin. Drug Discovery"},{"key":"D1RA02472H-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/pi.2378","volume":"57","author":"Rinaudo","year":"2008","journal-title":"Polym. Int."},{"key":"D1RA02472H-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1128\/CMR.15.2.167-193.2002","volume":"15","author":"Donlan","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"D1RA02472H-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s11051-006-9150-1","volume":"9","author":"Zhang","year":"2006","journal-title":"J. Nanoparticle Res."},{"key":"D1RA02472H-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1021\/am300292v","volume":"4","author":"Kumar","year":"2012","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D1RA02472H-(cit30)\/*[position()=1]","first-page":"77","volume":"3","author":"Lina","year":"1999","journal-title":"J. Microbiol. Methods"},{"key":"D1RA02472H-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3283","DOI":"10.1128\/AEM.02750-06","volume":"73","author":"Berney","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"D1RA02472H-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.1039\/C5TB00111K","volume":"3","author":"Lin","year":"2015","journal-title":"J. Mater. Chem. B"},{"key":"D1RA02472H-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/(SICI)1097-0029(19960301)33:4<320::AID-JEMT3>3.0.CO;2-T","volume":"33","author":"Roger","year":"1996","journal-title":"Microsc. Res. Tech."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/RA\/D1RA02472H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T18:12:14Z","timestamp":1783275134000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/11\/42\/26160-26167\/742675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":33,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2021,7,30]]}},"URL":"https:\/\/doi.org\/10.1039\/d1ra02472h","relation":{},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Quankui Lin (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-2870-6059","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Quankui Lin (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/B-3267-2013","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 29 March 2021; Accepted 24 July 2021;  Version of Record published 30 July 2021","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}