{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:08:47Z","timestamp":1782893327982,"version":"3.54.5"},"reference-count":36,"publisher":"Royal Society of Chemistry (RSC)","issue":"46","license":[{"start":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T00:00:00Z","timestamp":1631232000000},"content-version":"vor","delay-in-days":252,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018525","name":"Key Research and Development Program of Sichuan Province","doi-asserted-by":"publisher","award":["2020YFS0260"],"award-info":[{"award-number":["2020YFS0260"]}],"id":[{"id":"10.13039\/501100018525","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Carbon dots (CDS) have been proved to be a type of ideal biological imaging probe.<\/jats:p>","DOI":"10.1039\/d1ra04592j","type":"journal-article","created":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T06:10:35Z","timestamp":1631254235000},"page":"28809-28817","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["<i>In vivo<\/i>\n                    study of a novel, safe, rapid, and targeted red carbon dot probe for recognition of tumors with high expression of folate enzyme"],"prefix":"10.1039","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3967-8156","authenticated-orcid":false,"given":"Zhuoling","family":"Zhong","sequence":"first","affiliation":[{"name":"West China School of Pharmacy, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingying","family":"Li","sequence":"additional","affiliation":[{"name":"West China School of Pharmacy, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyao","family":"Liu","sequence":"additional","affiliation":[{"name":"West China School of Pharmacy, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanwei","family":"Zhang","sequence":"additional","affiliation":[{"name":"West China School of Pharmacy, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoping","family":"Xu","sequence":"additional","affiliation":[{"name":"West China School of Pharmacy, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyun","family":"Liao","sequence":"additional","affiliation":[{"name":"Chengdu Med Coll, Sch Pharm, 783, Xindu Ave, Chengdu 610500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1RA04592J\/cit1","first-page":"61","author":"Jemal","year":"2011","journal-title":"Ca-Cancer J. Clin."},{"key":"D1RA04592J\/cit2","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1093\/eurpub\/ckz216","volume":"30","author":"Mattiuzzi","year":"2020","journal-title":"Cent. Eur. J. Public Health"},{"key":"D1RA04592J\/cit3","doi-asserted-by":"crossref","first-page":"119182","DOI":"10.1016\/j.biomaterials.2019.04.027","volume":"219","author":"Bu","year":"2019","journal-title":"Biomaterials"},{"key":"D1RA04592J\/cit4","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1016\/j.metabol.2014.10.027","volume":"64","author":"Kalia","year":"2015","journal-title":"Metabolism"},{"key":"D1RA04592J\/cit5","doi-asserted-by":"crossref","first-page":"869","DOI":"10.12998\/wjcc.v6.i15.869","volume":"6","author":"Vacante","year":"2018","journal-title":"World J. Clin. Cases"},{"key":"D1RA04592J\/cit6","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.aca.2016.11.011","volume":"950","author":"Mazzu-Nascimento","year":"2017","journal-title":"Anal. Chim. Acta"},{"key":"D1RA04592J\/cit7","doi-asserted-by":"crossref","first-page":"5695","DOI":"10.1002\/anie.201004398","volume":"50","author":"He","year":"2011","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"D1RA04592J\/cit8","doi-asserted-by":"crossref","first-page":"10530","DOI":"10.1021\/acs.chemrev.5b00321","volume":"115","author":"Chinen","year":"2015","journal-title":"Chem. Rev."},{"key":"D1RA04592J\/cit9","first-page":"150","author":"Ehsanimehr","year":"2021","journal-title":"Eur. Polym. J."},{"key":"D1RA04592J\/cit10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1039\/C5NR07182H","volume":"8","author":"Ye","year":"2016","journal-title":"Nanoscale"},{"key":"D1RA04592J\/cit11","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1093\/annonc\/mdv250","volume":"26","author":"Ledermann","year":"2015","journal-title":"Ann. Oncol."},{"key":"D1RA04592J\/cit12","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.addr.2012.09.020","volume":"64","author":"Lu","year":"2012","journal-title":"Adv. Drug Delivery Rev."},{"key":"D1RA04592J\/cit13","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1016\/j.bios.2010.11.032","volume":"26","author":"Wang","year":"2011","journal-title":"Biosens. Bioelectron."},{"key":"D1RA04592J\/cit14","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.cbpa.2009.03.022","volume":"13","author":"Low","year":"2009","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D1RA04592J\/cit15","doi-asserted-by":"crossref","first-page":"195501","DOI":"10.1088\/1361-6528\/abdf02","volume":"32","author":"Ma","year":"2021","journal-title":"Nanotechnology"},{"key":"D1RA04592J\/cit16","first-page":"431","author":"Li","year":"2021","journal-title":"Coord. Chem. Rev."},{"key":"D1RA04592J\/cit17","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1002\/adma.201306192","volume":"26","author":"Zheng","year":"2014","journal-title":"Adv. Mater."},{"key":"D1RA04592J\/cit18","doi-asserted-by":"crossref","first-page":"7927","DOI":"10.1039\/C5NR01178G","volume":"7","author":"Zhu","year":"2015","journal-title":"Nanoscale"},{"key":"D1RA04592J\/cit19","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.envpol.2013.01.039","volume":"176","author":"Zhang","year":"2013","journal-title":"Environ. Pollut."},{"key":"D1RA04592J\/cit20","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1039\/C4CS00269E","volume":"44","author":"Lim","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"D1RA04592J\/cit21","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.talanta.2018.12.042","volume":"196","author":"Molaei","year":"2019","journal-title":"Talanta"},{"key":"D1RA04592J\/cit22","doi-asserted-by":"crossref","first-page":"6460","DOI":"10.1039\/C8RA08088G","volume":"9","author":"Molaei","year":"2019","journal-title":"RSC Adv."},{"key":"D1RA04592J\/cit23","doi-asserted-by":"crossref","first-page":"4634","DOI":"10.1039\/C8NR10059D","volume":"11","author":"Mintz","year":"2019","journal-title":"Nanoscale"},{"key":"D1RA04592J\/cit24","doi-asserted-by":"crossref","first-page":"12568","DOI":"10.1039\/c2jm31582c","volume":"22","author":"Song","year":"2012","journal-title":"J. Mater. Chem."},{"key":"D1RA04592J\/cit25","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bios.2014.08.052","volume":"64","author":"Liu","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"D1RA04592J\/cit26","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.snb.2016.02.123","volume":"230","author":"Lei","year":"2016","journal-title":"Sens. Actuators, B"},{"key":"D1RA04592J\/cit27","doi-asserted-by":"crossref","first-page":"11308","DOI":"10.1021\/ja904843x","volume":"131","author":"Sheng-Tao Yang","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"D1RA04592J\/cit28","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/smll.201101706","volume":"8","author":"Tao","year":"2012","journal-title":"Small"},{"key":"D1RA04592J\/cit29","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1016\/S0021-9258(17)41848-5","volume":"269","author":"Lee","year":"1994","journal-title":"J. Biol. Chem."},{"key":"D1RA04592J\/cit30","doi-asserted-by":"crossref","first-page":"7800","DOI":"10.1002\/anie.201301114","volume":"52","author":"Dong","year":"2013","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"D1RA04592J\/cit31","doi-asserted-by":"crossref","first-page":"085705","DOI":"10.1088\/1361-6528\/aaa321","volume":"29","author":"Zhu","year":"2018","journal-title":"Nanotechnology"},{"key":"D1RA04592J\/cit32","doi-asserted-by":"crossref","first-page":"7257","DOI":"10.1039\/C6TA01098A","volume":"4","author":"Wang","year":"2016","journal-title":"J. Mater. Chem. A"},{"key":"D1RA04592J\/cit33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.msec.2017.12.011","volume":"85","author":"Qiao","year":"2018","journal-title":"Mater. Sci. Eng., C"},{"key":"D1RA04592J\/cit34","doi-asserted-by":"crossref","first-page":"5360","DOI":"10.1002\/anie.201501193","volume":"54","author":"Jiang","year":"2015","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"D1RA04592J\/cit35","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.snb.2017.07.075","volume":"254","author":"Kumari","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D1RA04592J\/cit36","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/nrc774","volume":"2","author":"Tweedale","year":"2002","journal-title":"Nat. Rev. Cancer"}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/RA\/D1RA04592J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:12:49Z","timestamp":1782886369000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/11\/46\/28809-28817\/743487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":36,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2021,8,23]]}},"URL":"https:\/\/doi.org\/10.1039\/d1ra04592j","relation":{},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}