{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T04:31:25Z","timestamp":1789878685793,"version":"4.0.1"},"reference-count":125,"publisher":"Royal Society of Chemistry (RSC)","issue":"41","license":[{"start":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T00:00:00Z","timestamp":1633392000000},"content-version":"vor","delay-in-days":277,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100019404","name":"Shenzhen-Hong Kong Institute of Brain Science","doi-asserted-by":"publisher","award":["2019SHIBS0004"],"award-info":[{"award-number":["2019SHIBS0004"]}],"id":[{"id":"10.13039\/501100019404","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21602009"],"award-info":[{"award-number":["21602009"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation Commission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["GXWD20201231165807007-20200814103057002"],"award-info":[{"award-number":["GXWD20201231165807007-20200814103057002"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Sci."],"abstract":"<jats:p>\n                    Systematic investigation of various homoallylamines reveals\n                    <jats:italic>N-p<\/jats:italic>\n                    -methoxybenzyl homoallylamine as the optimal 2-aza-Cope reaction moiety for development of highly efficient formaldehyde fluorescent probes for\n                    <jats:italic>in vitro<\/jats:italic>\n                    and\n                    <jats:italic>in vivo<\/jats:italic>\n                    imaging.\n                  <\/jats:p>","DOI":"10.1039\/d1sc04387k","type":"journal-article","created":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T04:58:31Z","timestamp":1633669111000},"page":"13857-13869","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Systematic investigation of the aza-Cope reaction for fluorescence imaging of formaldehyde\n                    <i>in vitro<\/i>\n                    and\n                    <i>in vivo<\/i>"],"prefix":"10.1039","volume":"12","author":[{"given":"Yimeng","family":"Du","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3489-9929","authenticated-orcid":false,"given":"Meirong","family":"Huang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shushu","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzheng","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kongke","family":"Liao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8210-2531","authenticated-orcid":false,"given":"Xinhao","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"},{"name":"Shenzhen Bay Laboratory, Shenzhen 518132, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Dong","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"},{"name":"Shenzhen Bay Laboratory, Shenzhen 518132, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5578-5314","authenticated-orcid":false,"given":"Tao","family":"Peng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2021]]},"reference":[{"key":"D1SC04387K\/cit1","volume-title":"Formaldehyde (Concise International Chemical Assessment Documents)","author":"Liteplo","year":"2002","unstructured":"R.Liteplo ,  R.Beauchamp ,  M.Meek  and  R.Chenier ,  Formaldehyde (Concise International Chemical Assessment Documents) ,  World Health Organization ,  Geneva ,  2002"},{"key":"D1SC04387K\/cit2","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1021\/cr800399g","volume":"110","author":"Salthammer","year":"2010","journal-title":"Chem. Rev."},{"key":"D1SC04387K\/cit3a","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2174\/1389557033488187","volume":"3","author":"Huba","year":"2003","journal-title":"Mini-Rev. Med. Chem."},{"key":"D1SC04387K\/cit3b","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/jnc.12356","volume":"127","author":"Tulpule","year":"2013","journal-title":"J. Neurochem."},{"key":"D1SC04387K\/cit4","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1111\/j.1742-4658.2009.07142.x","volume":"276","author":"Forneris","year":"2009","journal-title":"FEBS J."},{"key":"D1SC04387K\/cit5","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/nature04433","volume":"439","author":"Tsukada","year":"2006","journal-title":"Nature"},{"key":"D1SC04387K\/cit6a","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nchembio.687","volume":"7","author":"Jia","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"D1SC04387K\/cit6b","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.molcel.2012.10.015","volume":"49","author":"Zheng","year":"2013","journal-title":"Mol. Cell"},{"key":"D1SC04387K\/cit6c","doi-asserted-by":"crossref","first-page":"11571","DOI":"10.1074\/jbc.M113.546168","volume":"289","author":"Feng","year":"2014","journal-title":"J. Biol. Chem."},{"key":"D1SC04387K\/cit7","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0161-813X(03)00117-7","volume":"25","author":"O'Sullivan","year":"2004","journal-title":"Neurotoxicology"},{"key":"D1SC04387K\/cit8","doi-asserted-by":"crossref","first-page":"17826","DOI":"10.1074\/jbc.M109.006262","volume":"284","author":"Tralau","year":"2009","journal-title":"J. Biol. Chem."},{"key":"D1SC04387K\/cit9","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/nature23481","volume":"548","author":"Burgos-Barragan","year":"2017","journal-title":"Nature"},{"key":"D1SC04387K\/cit10","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0890-6238(03)00013-3","volume":"17","author":"Harris","year":"2003","journal-title":"Reprod. Toxicol."},{"key":"D1SC04387K\/cit11a","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0009-2797(00)00272-6","volume":"130\u2013132","author":"Teng","year":"2001","journal-title":"Chem.-Biol. Interact."},{"key":"D1SC04387K\/cit11b","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.cbi.2011.01.017","volume":"191","author":"MacAllister","year":"2011","journal-title":"Chem.-Biol. Interact."},{"key":"D1SC04387K\/cit12a","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15298668591394275","volume":"46","author":"Heck","year":"1985","journal-title":"Am. Ind. Hyg. Assoc. J."},{"key":"D1SC04387K\/cit12b","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.yrtph.2004.05.001","volume":"40","author":"Heck","year":"2004","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"D1SC04387K\/cit12c","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1093\/toxsci\/kfq303","volume":"118","author":"Andersen","year":"2010","journal-title":"Toxicol. Sci."},{"key":"D1SC04387K\/cit12d","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s11357-012-9388-8","volume":"35","author":"Tong","year":"2013","journal-title":"Age"},{"key":"D1SC04387K\/cit13","first-page":"1","volume-title":"Vitam. Horm.","volume":"79","author":"Fox","year":"2008","unstructured":"J. T.Fox  and  P. J.Stover , in  Vitam. Horm. ,  Academic Press ,  2008 ,  vol. 79 ,  pp. 1\u201344"},{"key":"D1SC04387K\/cit14a","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/S1470-2045(09)70358-4","volume":"10","author":"Baan","year":"2009","journal-title":"Lancet Oncol."},{"key":"D1SC04387K\/cit14b","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/ijc.25349","volume":"128","author":"Hayami","year":"2011","journal-title":"Int. J. Cancer"},{"key":"D1SC04387K\/cit14c","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.molcel.2015.08.020","volume":"60","author":"Pontel","year":"2015","journal-title":"Mol. Cell"},{"key":"D1SC04387K\/cit14d","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.molcel.2020.11.040","volume":"80","author":"Shen","year":"2020","journal-title":"Mol. Cell"},{"key":"D1SC04387K\/cit15a","first-page":"59","volume-title":"Neurodegeneration","author":"Miao","year":"2012","unstructured":"J.Miao  and  R.He , in  Neurodegeneration , ed.  L. M. Martins  and  S. H. Y. Loh ,  InTech ,  Rijeka ,  2012 ,  pp. 59\u201376"},{"key":"D1SC04387K\/cit15b","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1021\/acs.chemrestox.9b00090","volume":"32","author":"Wang","year":"2019","journal-title":"Chem. Res. Toxicol."},{"key":"D1SC04387K\/cit16","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.lfs.2005.04.064","volume":"78","author":"Ucar","year":"2005","journal-title":"Life Sci."},{"key":"D1SC04387K\/cit17a","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.lfs.2006.01.017","volume":"79","author":"Obata","year":"2006","journal-title":"Life Sci."},{"key":"D1SC04387K\/cit17b","doi-asserted-by":"crossref","first-page":"3669","DOI":"10.1096\/fj.201701239R","volume":"32","author":"Tan","year":"2018","journal-title":"FASEB J."},{"key":"D1SC04387K\/cit18","doi-asserted-by":"crossref","first-page":"e10234","DOI":"10.1371\/journal.pone.0010234","volume":"5","author":"Tong","year":"2010","journal-title":"PLoS One"},{"key":"D1SC04387K\/cit19","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.neurobiolaging.2009.07.013","volume":"32","author":"Tong","year":"2011","journal-title":"Neurobiol. Aging"},{"key":"D1SC04387K\/cit20","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/s42003-019-0694-x","volume":"2","author":"Ai","year":"2019","journal-title":"Commun. Biol."},{"key":"D1SC04387K\/cit21a","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1016\/j.cclet.2017.07.018","volume":"28","author":"Xu","year":"2017","journal-title":"Chin. Chem. Lett."},{"key":"D1SC04387K\/cit21b","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cbpa.2017.04.010","volume":"39","author":"Bruemmer","year":"2017","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D1SC04387K\/cit21c","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1021\/acs.accounts.9b00386","volume":"52","author":"Ohata","year":"2019","journal-title":"Acc. Chem. Res."},{"key":"D1SC04387K\/cit21d","doi-asserted-by":"crossref","first-page":"4036","DOI":"10.1039\/C8CS00956B","volume":"48","author":"Tang","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"D1SC04387K\/cit21e","doi-asserted-by":"crossref","first-page":"13734","DOI":"10.1002\/anie.201909690","volume":"59","author":"Bruemmer","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D1SC04387K\/cit21f","doi-asserted-by":"crossref","first-page":"213109","DOI":"10.1016\/j.ccr.2019.213109","volume":"404","author":"Liu","year":"2020","journal-title":"Coord. Chem. Rev."},{"key":"D1SC04387K\/cit22a","doi-asserted-by":"crossref","first-page":"10886","DOI":"10.1021\/jacs.5b05340","volume":"137","author":"Brewer","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit22b","doi-asserted-by":"crossref","first-page":"10890","DOI":"10.1021\/jacs.5b05339","volume":"137","author":"Roth","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit22c","doi-asserted-by":"crossref","first-page":"5338","DOI":"10.1021\/jacs.6b12460","volume":"139","author":"Bruemmer","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit23a","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1002\/anie.201510373","volume":"55","author":"Tang","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D1SC04387K\/cit23b","doi-asserted-by":"crossref","first-page":"11247","DOI":"10.1039\/C6CC06158C","volume":"52","author":"Lee","year":"2016","journal-title":"Chem. Commun."},{"key":"D1SC04387K\/cit23c","doi-asserted-by":"crossref","first-page":"9359","DOI":"10.1021\/acs.analchem.6b02879","volume":"88","author":"Tang","year":"2016","journal-title":"Anal. Chem."},{"key":"D1SC04387K\/cit23d","doi-asserted-by":"crossref","first-page":"5472","DOI":"10.1039\/C7AY01786C","volume":"9","author":"Wu","year":"2017","journal-title":"Anal. Methods"},{"key":"D1SC04387K\/cit23e","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.7150\/thno.19554","volume":"7","author":"Liang","year":"2017","journal-title":"Theranostics"},{"key":"D1SC04387K\/cit23f","doi-asserted-by":"crossref","first-page":"024005","DOI":"10.1088\/2050-6120\/aa6773","volume":"5","author":"Tang","year":"2017","journal-title":"Methods Appl. Fluoresc."},{"key":"D1SC04387K\/cit23g","doi-asserted-by":"crossref","first-page":"7193","DOI":"10.1016\/j.tet.2018.10.051","volume":"74","author":"Han","year":"2018","journal-title":"Tetrahedron"},{"key":"D1SC04387K\/cit23h","doi-asserted-by":"crossref","first-page":"8325","DOI":"10.1039\/C8NJ01240G","volume":"42","author":"Xu","year":"2018","journal-title":"New J. Chem."},{"key":"D1SC04387K\/cit23i","doi-asserted-by":"crossref","first-page":"12010","DOI":"10.1039\/C8CC06155F","volume":"54","author":"Liang","year":"2018","journal-title":"Chem. Commun."},{"key":"D1SC04387K\/cit23j","doi-asserted-by":"crossref","first-page":"18189","DOI":"10.1021\/acsomega.8b02590","volume":"3","author":"Chen","year":"2018","journal-title":"ACS Omega"},{"key":"D1SC04387K\/cit23k","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1039\/C9AY00553F","volume":"11","author":"Xin","year":"2019","journal-title":"Anal. Methods"},{"key":"D1SC04387K\/cit23l","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1039\/C8AN02108B","volume":"144","author":"Xin","year":"2019","journal-title":"Analyst"},{"key":"D1SC04387K\/cit23m","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/slct.201803673","volume":"4","author":"Cheng","year":"2019","journal-title":"ChemistrySelect"},{"key":"D1SC04387K\/cit23n","doi-asserted-by":"crossref","first-page":"6922","DOI":"10.1039\/C9AN01778J","volume":"144","author":"Chen","year":"2019","journal-title":"Analyst"},{"key":"D1SC04387K\/cit23o","doi-asserted-by":"crossref","first-page":"112701","DOI":"10.1016\/j.jphotochem.2020.112701","volume":"400","author":"Yuan","year":"2020","journal-title":"J. Photochem. Photobiol., A"},{"key":"D1SC04387K\/cit23p","doi-asserted-by":"crossref","first-page":"12282","DOI":"10.1021\/acs.analchem.0c01918","volume":"92","author":"Ma","year":"2020","journal-title":"Anal. Chem."},{"key":"D1SC04387K\/cit23q","doi-asserted-by":"crossref","first-page":"3670","DOI":"10.1021\/acs.jafc.9b08114","volume":"68","author":"Ding","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"D1SC04387K\/cit23r","doi-asserted-by":"crossref","first-page":"128354","DOI":"10.1016\/j.snb.2020.128354","volume":"320","author":"Cao","year":"2020","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit23s","doi-asserted-by":"crossref","first-page":"117789","DOI":"10.1016\/j.saa.2019.117789","volume":"228","author":"Jiang","year":"2020","journal-title":"Spectrochim. Acta, Part A"},{"key":"D1SC04387K\/cit23t","doi-asserted-by":"crossref","first-page":"129494","DOI":"10.1016\/j.snb.2021.129494","volume":"332","author":"Zhou","year":"2021","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit23u","doi-asserted-by":"crossref","first-page":"109156","DOI":"10.1016\/j.dyepig.2021.109156","volume":"188","author":"Nasirian","year":"2021","journal-title":"Dyes Pigm."},{"key":"D1SC04387K\/cit23v","doi-asserted-by":"crossref","first-page":"16408","DOI":"10.1021\/jacs.8b09794","volume":"140","author":"Xu","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit23w","doi-asserted-by":"crossref","first-page":"14417","DOI":"10.1021\/acsomega.8b01660","volume":"3","author":"Chen","year":"2018","journal-title":"ACS Omega"},{"key":"D1SC04387K\/cit23x","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.snb.2018.01.128","volume":"260","author":"Wu","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit23y","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1039\/C7AN01488K","volume":"143","author":"Song","year":"2018","journal-title":"Analyst"},{"key":"D1SC04387K\/cit23z","doi-asserted-by":"crossref","first-page":"9582","DOI":"10.1039\/C6CC04254F","volume":"52","author":"He","year":"2016","journal-title":"Chem. Commun."},{"key":"D1SC04387K\/cit23aa","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.dyepig.2016.11.020","volume":"138","author":"Liu","year":"2017","journal-title":"Dyes Pigm."},{"key":"D1SC04387K\/cit23ab","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.talanta.2018.07.001","volume":"189","author":"Cao","year":"2018","journal-title":"Talanta"},{"key":"D1SC04387K\/cit23ac","doi-asserted-by":"crossref","first-page":"131617","DOI":"10.1016\/j.tet.2020.131617","volume":"76","author":"Cai","year":"2020","journal-title":"Tetrahedron"},{"key":"D1SC04387K\/cit23ad","doi-asserted-by":"crossref","first-page":"118949","DOI":"10.1016\/j.saa.2020.118949","volume":"245","author":"Cai","year":"2021","journal-title":"Spectrochim. Acta, Part A"},{"key":"D1SC04387K\/cit23ae","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1021\/acs.analchem.9b04576","volume":"92","author":"Cheng","year":"2020","journal-title":"Anal. Chem."},{"key":"D1SC04387K\/cit23af","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1021\/acssensors.8b00835","volume":"3","author":"Li","year":"2018","journal-title":"ACS Sens."},{"key":"D1SC04387K\/cit23ag","doi-asserted-by":"crossref","first-page":"131411","DOI":"10.1016\/j.tet.2020.131411","volume":"76","author":"Wechakorn","year":"2020","journal-title":"Tetrahedron"},{"key":"D1SC04387K\/cit23ah","doi-asserted-by":"crossref","first-page":"3499","DOI":"10.1038\/s41596-020-0384-7","volume":"15","author":"Tang","year":"2020","journal-title":"Nat. Protoc."},{"key":"D1SC04387K\/cit24a","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.1039\/C5CC09796G","volume":"52","author":"He","year":"2016","journal-title":"Chem. Commun."},{"key":"D1SC04387K\/cit24b","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.talanta.2016.08.010","volume":"160","author":"Xu","year":"2016","journal-title":"Talanta"},{"key":"D1SC04387K\/cit24c","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1039\/C6AN00473C","volume":"141","author":"Li","year":"2016","journal-title":"Analyst"},{"key":"D1SC04387K\/cit24d","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.snb.2016.10.039","volume":"241","author":"Xie","year":"2017","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit24e","doi-asserted-by":"crossref","first-page":"5616","DOI":"10.1039\/C7SC00373K","volume":"8","author":"Li","year":"2017","journal-title":"Chem. Sci."},{"key":"D1SC04387K\/cit24f","doi-asserted-by":"crossref","first-page":"3724","DOI":"10.1021\/acs.analchem.7b00044","volume":"89","author":"Singha","year":"2017","journal-title":"Anal. Chem."},{"key":"D1SC04387K\/cit24g","doi-asserted-by":"crossref","first-page":"6520","DOI":"10.1039\/C7CC03050A","volume":"53","author":"Xie","year":"2017","journal-title":"Chem. Commun."},{"key":"D1SC04387K\/cit24h","doi-asserted-by":"crossref","first-page":"4073","DOI":"10.1039\/C7SC00748E","volume":"8","author":"Brewer","year":"2017","journal-title":"Chem. Sci."},{"key":"D1SC04387K\/cit24i","doi-asserted-by":"crossref","first-page":"7851","DOI":"10.1039\/C7SC03719H","volume":"8","author":"Dou","year":"2017","journal-title":"Chem. Sci."},{"key":"D1SC04387K\/cit24j","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.snb.2018.07.017","volume":"273","author":"Gao","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit24k","doi-asserted-by":"crossref","first-page":"488","DOI":"10.3389\/fchem.2018.00488","volume":"6","author":"Yang","year":"2018","journal-title":"Front. Chem."},{"key":"D1SC04387K\/cit24l","doi-asserted-by":"crossref","first-page":"12361","DOI":"10.1039\/C8NJ02467G","volume":"42","author":"Yang","year":"2018","journal-title":"New J. Chem."},{"key":"D1SC04387K\/cit24m","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.snb.2018.05.069","volume":"270","author":"Yang","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit24n","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1039\/C8AY00849C","volume":"10","author":"Yang","year":"2018","journal-title":"Anal. Methods"},{"key":"D1SC04387K\/cit24o","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.aca.2018.05.065","volume":"1033","author":"Zhang","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"D1SC04387K\/cit24p","doi-asserted-by":"crossref","first-page":"4628","DOI":"10.1039\/C8OB00989A","volume":"16","author":"Xie","year":"2018","journal-title":"Org. Biomol. Chem."},{"key":"D1SC04387K\/cit24q","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.snb.2017.11.043","volume":"258","author":"Zhou","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D1SC04387K\/cit24r","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1021\/acssensors.8b00664","volume":"3","author":"Zhao","year":"2018","journal-title":"ACS Sens."},{"key":"D1SC04387K\/cit24s","doi-asserted-by":"crossref","first-page":"11844","DOI":"10.1039\/C9NJ02352F","volume":"43","author":"Li","year":"2019","journal-title":"New J. Chem."},{"key":"D1SC04387K\/cit24t","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1039\/C9AY00281B","volume":"11","author":"Wang","year":"2019","journal-title":"Anal. Methods"},{"key":"D1SC04387K\/cit24u","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1021\/acsabm.8b00699","volume":"2","author":"Ji","year":"2019","journal-title":"ACS Appl. Bio Mater."},{"key":"D1SC04387K\/cit24v","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1039\/D0CC00676A","volume":"56","author":"Chen","year":"2020","journal-title":"Chem. Commun."},{"key":"D1SC04387K\/cit24w","doi-asserted-by":"crossref","first-page":"117988","DOI":"10.1016\/j.saa.2019.117988","volume":"229","author":"Hao","year":"2020","journal-title":"Spectrochim. Acta, Part A"},{"key":"D1SC04387K\/cit25a","doi-asserted-by":"crossref","first-page":"7508","DOI":"10.1002\/anie.201802143","volume":"57","author":"Bruemmer","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D1SC04387K\/cit25b","doi-asserted-by":"crossref","first-page":"8462","DOI":"10.1021\/jacs.8b13898","volume":"141","author":"Liu","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit26","doi-asserted-by":"crossref","first-page":"16352","DOI":"10.1002\/anie.202001425","volume":"59","author":"Zhang","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D1SC04387K\/cit27","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1021\/cr940337h","volume":"105","author":"Jung","year":"2005","journal-title":"Chem. Rev."},{"key":"D1SC04387K\/cit28a","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1021\/cr00061a001","volume":"84","author":"Lutz","year":"1984","journal-title":"Chem. Rev."},{"key":"D1SC04387K\/cit28b","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1021\/ar00020a005","volume":"25","author":"Overman","year":"1992","journal-title":"Acc. Chem. Res."},{"key":"D1SC04387K\/cit29a","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1021\/ja021010y","volume":"125","author":"Minegishi","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit29b","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1021\/jo062586z","volume":"72","author":"Brotzel","year":"2007","journal-title":"J. Org. Chem."},{"key":"D1SC04387K\/cit30a","doi-asserted-by":"crossref","first-page":"8666","DOI":"10.1021\/ja035282s","volume":"125","author":"Miura","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit30b","doi-asserted-by":"crossref","first-page":"5597","DOI":"10.1021\/ja068551y","volume":"129","author":"Sunahara","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit31a","doi-asserted-by":"crossref","first-page":"7581","DOI":"10.1002\/anie.200602877","volume":"45","author":"Dirksen","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"D1SC04387K\/cit31b","doi-asserted-by":"crossref","first-page":"10358","DOI":"10.1021\/acs.chemrev.7b00090","volume":"117","author":"K\u00f6lmel","year":"2017","journal-title":"Chem. Rev."},{"key":"D1SC04387K\/cit31c","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1002\/poc.941","volume":"18","author":"Godoy-Alc\u00e1ntar","year":"2005","journal-title":"J. Phys. Org. Chem."},{"key":"D1SC04387K\/cit32","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1039\/C2CS35273G","volume":"42","author":"Fan","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"D1SC04387K\/cit34","doi-asserted-by":"crossref","first-page":"4888","DOI":"10.1021\/ja043919h","volume":"127","author":"Urano","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit35","doi-asserted-by":"crossref","first-page":"10189","DOI":"10.1021\/ja902511p","volume":"131","author":"Izumi","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit36a","doi-asserted-by":"crossref","first-page":"13510","DOI":"10.1021\/ja305802v","volume":"134","author":"Yuan","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"D1SC04387K\/cit36b","doi-asserted-by":"crossref","first-page":"11696","DOI":"10.1002\/chem.201502226","volume":"21","author":"Chen","year":"2015","journal-title":"Chem.\u2013Eur. J."},{"key":"D1SC04387K\/cit37a","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/carcin\/bgp324","volume":"31","author":"Lim","year":"2010","journal-title":"Carcinogenesis"},{"key":"D1SC04387K\/cit37b","doi-asserted-by":"crossref","first-page":"e58957","DOI":"10.1371\/journal.pone.0058957","volume":"8","author":"Liu","year":"2013","journal-title":"PLoS One"},{"key":"D1SC04387K\/cit38","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1517\/13543776.2016.1165209","volume":"26","author":"Stazi","year":"2016","journal-title":"Expert Opin. Ther. Pat."},{"key":"D1SC04387K\/cit39","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.chembiol.2006.05.004","volume":"13","author":"Lee","year":"2006","journal-title":"Chem. Biol."},{"key":"D1SC04387K\/cit40","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1038\/nsmb.2173","volume":"18","author":"Rosado","year":"2011","journal-title":"Nat. Struct. Mol. Biol."},{"key":"D1SC04387K\/cit41","doi-asserted-by":"crossref","first-page":"472","DOI":"10.2174\/1568026615666150813142215","volume":"16","author":"Su","year":"2016","journal-title":"Curr. Top. Med. Chem."},{"key":"D1SC04387K\/cit42a","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1211\/0022357021778268","volume":"54","author":"Goldberg","year":"2010","journal-title":"J. Pharm. Pharmacol."},{"key":"D1SC04387K\/cit42b","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/s41571-021-00507-y","volume":"18","author":"Melero","year":"2021","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"D1SC04387K\/cit43","doi-asserted-by":"crossref","first-page":"6407","DOI":"10.1021\/jacs.5b04097","volume":"137","author":"Li","year":"2015","journal-title":"J. Am. Chem. Soc."}],"container-title":["Chemical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2021\/SC\/D1SC04387K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:45:30Z","timestamp":1783014330000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/sc\/article\/12\/41\/13857-13869\/746675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":125,"journal-issue":{"issue":"41","published-print":{"date-parts":[[2021,10,27]]}},"URL":"https:\/\/doi.org\/10.1039\/d1sc04387k","relation":{},"ISSN":["2041-6520","2041-6539"],"issn-type":[{"value":"2041-6520","type":"print"},{"value":"2041-6539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}