{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:39:13Z","timestamp":1782891553924,"version":"3.54.5"},"reference-count":48,"publisher":"Royal Society of Chemistry (RSC)","issue":"21","license":[{"start":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T00:00:00Z","timestamp":1662163200000},"content-version":"vor","delay-in-days":245,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100009033","name":"Center of Innovation Program","doi-asserted-by":"publisher","award":["JPMJCE1305"],"award-info":[{"award-number":["JPMJCE1305"]}],"id":[{"id":"10.13039\/501100009033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K15577"],"award-info":[{"award-number":["21K15577"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19H01179"],"award-info":[{"award-number":["19H01179"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>\n                    The influence of Gd-DOTA locations on the fate of imaging probe\n                    <jats:italic>in vivo<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1039\/d2bm01213h","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T20:41:20Z","timestamp":1662151280000},"page":"6244-6257","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The effect of Gd-DOTA locations within PLGA-\n                    <i>b<\/i>\n                    -PEG micelle encapsulated IR-1061 on bimodal over-1000 nm near-infrared fluorescence and magnetic resonance imaging"],"prefix":"10.1039","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5871-0601","authenticated-orcid":false,"given":"Thi Kim Dung","family":"Doan","sequence":"first","affiliation":[{"name":"Research Institute for Biomedical Science, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan"},{"name":"Division of Functional Imaging, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa 277-8577, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3398-3993","authenticated-orcid":false,"given":"Masakazu","family":"Umezawa","sequence":"additional","affiliation":[{"name":"Department of Material Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5744-3679","authenticated-orcid":false,"given":"Kyohei","family":"Okubo","sequence":"additional","affiliation":[{"name":"Department of Material Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8510-2935","authenticated-orcid":false,"given":"Masao","family":"Kamimura","sequence":"additional","affiliation":[{"name":"Department of Material Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Division of Functional Imaging, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa 277-8577, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Fujii","sequence":"additional","affiliation":[{"name":"Division of Functional Imaging, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa 277-8577, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Soga","sequence":"additional","affiliation":[{"name":"Research Institute for Biomedical Science, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan"},{"name":"Department of Material Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2BM01213H\/cit1\/1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/978-981-15-9627-8_11","volume-title":"Transparency in Biology: Making the Invisible Visible","author":"Doan","year":"2021","unstructured":"T. K. D.Doan , in  Transparency in Biology: Making the Invisible Visible , ed.  K. Soga ,  M. Umezawa  and  K. Okubo ,  Springer Singapore ,  Singapore ,  2021 , pp.  223\u2013263 ,  10.1007\/978-981-15-9627-8_11"},{"key":"D2BM01213H\/cit2\/1","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1039\/D1BM01574E","volume":"10","author":"Doan","year":"2022","journal-title":"Biomater. Sci."},{"key":"D2BM01213H\/cit3\/1","doi-asserted-by":"crossref","first-page":"9108","DOI":"10.1021\/jacs.5b04509","volume":"137","author":"Harrison","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"D2BM01213H\/cit4\/1","doi-asserted-by":"crossref","first-page":"4168","DOI":"10.7150\/thno.34390","volume":"9","author":"Hu","year":"2019","journal-title":"Theranostics"},{"key":"D2BM01213H\/cit5\/1","doi-asserted-by":"crossref","first-page":"10699","DOI":"10.1039\/C8NR02017E","volume":"10","author":"Ma","year":"2018","journal-title":"Nanoscale"},{"key":"D2BM01213H\/cit6\/1","doi-asserted-by":"crossref","first-page":"6960","DOI":"10.1073\/pnas.1701944114","volume":"114","author":"Marangoni","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D2BM01213H\/cit7\/1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.biomaterials.2017.10.032","volume":"152","author":"Shi","year":"2018","journal-title":"Biomaterials"},{"key":"D2BM01213H\/cit8\/1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2494\/photopolymer.33.117","volume":"33","author":"Doan","year":"2020","journal-title":"J. Photopolym. Sci. Technol."},{"key":"D2BM01213H\/cit9\/1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jcis.2015.06.046","volume":"457","author":"Chen","year":"2015","journal-title":"J. Colloid Interface Sci."},{"key":"D2BM01213H\/cit10\/1","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1038\/s41467-018-05113-8","volume":"9","author":"Wang","year":"2018","journal-title":"Nat. Commun."},{"key":"D2BM01213H\/cit11\/1","doi-asserted-by":"crossref","first-page":"10331","DOI":"10.1021\/jacs.9b03649","volume":"141","author":"Yan","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D2BM01213H\/cit12\/1","doi-asserted-by":"crossref","first-page":"9448","DOI":"10.1039\/C9TC01929D","volume":"7","author":"Zhou","year":"2019","journal-title":"J. Mater. Chem. C"},{"key":"D2BM01213H\/cit13\/1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-981-15-9627-8_1","volume-title":"Transparency in Biology: Making the Invisible Visible","author":"Soga","year":"2021","unstructured":"K.Soga , in  Transparency in Biology: Making the Invisible Visible , ed.  K. Soga ,  M. Umezawa  and  K. Okubo ,  Springer Singapore ,  Singapore ,  2021 , pp.  3\u201332 ,  10.1007\/978-981-15-9627-8_1"},{"key":"D2BM01213H\/cit14\/1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3390\/nano6090163","volume":"6","author":"Doan","year":"2016","journal-title":"Nanomaterials"},{"key":"D2BM01213H\/cit15\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1080\/14686996.2021.1887712","volume":"22","author":"Okubo","year":"2021","journal-title":"Sci. Technol. Adv. Mater."},{"key":"D2BM01213H\/cit16\/1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1246\/cl.210700","volume":"51","author":"Doan","year":"2022","journal-title":"Chem. Lett."},{"key":"D2BM01213H\/cit17\/1","doi-asserted-by":"crossref","first-page":"4798","DOI":"10.1002\/ejic.201500688","volume":"2015","author":"Fontes","year":"2015","journal-title":"Eur. J. Inorg. Chem."},{"key":"D2BM01213H\/cit18\/1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/pj.2012.103","volume":"45","author":"Marimuthu","year":"2013","journal-title":"Polym. J."},{"key":"D2BM01213H\/cit19\/1","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1016\/j.biomaterials.2011.12.013","volume":"33","author":"Liu","year":"2012","journal-title":"Biomaterials"},{"key":"D2BM01213H\/cit20\/1","doi-asserted-by":"crossref","first-page":"7836","DOI":"10.1021\/ja101518v","volume":"132","author":"Kielar","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"D2BM01213H\/cit21\/1","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.nano.2011.03.007","volume":"7","author":"Kojima","year":"2011","journal-title":"Nanomedicine"},{"key":"D2BM01213H\/cit22\/1","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1002\/(SICI)1521-3765(19991001)5:10<2977::AID-CHEM2977>3.0.CO;2-T","volume":"5","author":"Andr\u00e9","year":"1999","journal-title":"Chem. \u2013 Eur. J."},{"key":"D2BM01213H\/cit23\/1","doi-asserted-by":"crossref","first-page":"S232","DOI":"10.1097\/00004424-198809001-00048","volume":"23","author":"Meyer","year":"1988","journal-title":"Invest. Radiol."},{"key":"D2BM01213H\/cit24\/1","doi-asserted-by":"crossref","first-page":"e1907574","DOI":"10.1002\/smll.201907574","volume":"16","author":"Alberg","year":"2020","journal-title":"Small"},{"key":"D2BM01213H\/cit25\/1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.ijpharm.2018.10.011","volume":"552","author":"Xiao","year":"2018","journal-title":"Int. J. Pharm."},{"key":"D2BM01213H\/cit26\/1","doi-asserted-by":"crossref","first-page":"9138","DOI":"10.1021\/la401556k","volume":"29","author":"Liu","year":"2013","journal-title":"Langmuir"},{"key":"D2BM01213H\/cit27\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1477-3155-12-5","volume":"12","author":"Shang","year":"2014","journal-title":"J. Nanobiotechnol."},{"key":"D2BM01213H\/cit28\/1","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1016\/j.bbamem.2009.06.022","volume":"1788","author":"Li","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"D2BM01213H\/cit29\/1","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2116\/analsci.20SCP09","volume":"37","author":"Umezawa","year":"2021","journal-title":"Anal. Sci."},{"key":"D2BM01213H\/cit30\/1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1021\/acsnanoscienceau.1c00010","volume":"1","author":"Ueya","year":"2021","journal-title":"ACS Nanosci. Au"},{"key":"D2BM01213H\/cit31\/1","doi-asserted-by":"crossref","first-page":"11811","DOI":"10.1002\/chem.202101701","volume":"27","author":"Leone","year":"2021","journal-title":"Chem. \u2013 Eur. J."},{"key":"D2BM01213H\/cit32\/1","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1038\/s41467-019-09342-3","volume":"10","author":"Clough","year":"2019","journal-title":"Nat. Commun."},{"key":"D2BM01213H\/cit33\/1","doi-asserted-by":"crossref","first-page":"12917","DOI":"10.1039\/c1jm00005e","volume":"21","author":"Grogna","year":"2011","journal-title":"J. Mater. Chem."},{"key":"D2BM01213H\/cit34\/1","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1097\/RLI.0b013e3181ee5a9e","volume":"45","author":"Dumas","year":"2010","journal-title":"Invest. Radiol."},{"key":"D2BM01213H\/cit35\/1","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3389\/fchem.2018.00158","volume":"6","author":"Leone","year":"2018","journal-title":"Front. Chem."},{"key":"D2BM01213H\/cit36\/1","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1039\/B717390C","volume":"2008","author":"Livramento","year":"2008","journal-title":"Dalton Trans."},{"key":"D2BM01213H\/cit37\/1","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/RLI.0000000000000563","volume":"54","author":"Robic","year":"2019","journal-title":"Invest. Radiol."},{"key":"D2BM01213H\/cit38\/1","doi-asserted-by":"crossref","first-page":"6656","DOI":"10.1073\/pnas.1103573108","volume":"108","author":"Choi","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D2BM01213H\/cit39\/1","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/nbt1340","volume":"25","author":"Choi","year":"2007","journal-title":"Nat. Biotechnol."},{"key":"D2BM01213H\/cit40\/1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.2217\/17435889.3.5.703","volume":"3","author":"Longmire","year":"2008","journal-title":"Nanomedicine"},{"key":"D2BM01213H\/cit41\/1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00726-005-0289-3","volume":"30","author":"Werle","year":"2006","journal-title":"Amino Acids"},{"key":"D2BM01213H\/cit42\/1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/toxsci\/kfs306","volume":"131","author":"Gaiser","year":"2012","journal-title":"Toxicol. Sci."},{"key":"D2BM01213H\/cit43\/1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/10937404.2020.1751756","volume":"23","author":"Kermanizadeh","year":"2020","journal-title":"J. Toxicol. Environ. Health, Part B"},{"key":"D2BM01213H\/cit44\/1","doi-asserted-by":"crossref","first-page":"3941","DOI":"10.1590\/0001-3765201820180586","volume":"90","author":"Fernandes","year":"2018","journal-title":"An. Acad. Bras. Cienc."},{"key":"D2BM01213H\/cit45\/1","first-page":"2636","volume":"38","author":"Harrison Jr.","year":"1978","journal-title":"Cancer Res."},{"key":"D2BM01213H\/cit46\/1","doi-asserted-by":"crossref","first-page":"e3772","DOI":"10.1371\/journal.pone.0003772","volume":"3","author":"Mazzaccara","year":"2008","journal-title":"PLoS One"},{"key":"D2BM01213H\/cit47\/1","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/ame2.12139","volume":"3","author":"Silva-Santana","year":"2020","journal-title":"Anim. Models Exp. Med."},{"key":"D2BM01213H\/cit48\/1","unstructured":"Japan, SLC Inc., Laboratory animals, BALB\/cCrSlc,  https:\/\/www.jslc.co.jp\/pdf\/mouse\/003_BALBc2013.pdf"}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/BM\/D2BM01213H","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/BM\/D2BM01213H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:50:11Z","timestamp":1782885011000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/10\/21\/6244-6257\/756246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":48,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2022,10,25]]}},"URL":"https:\/\/doi.org\/10.1039\/d2bm01213h","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}