{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:43:15Z","timestamp":1790660595504,"version":"4.1.0"},"reference-count":112,"publisher":"Royal Society of Chemistry (RSC)","issue":"1","license":[{"start":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T00:00:00Z","timestamp":1699920000000},"content-version":"am","delay-in-days":317,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFE0103100"],"award-info":[{"award-number":["2021YFE0103100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2400600"],"award-info":[{"award-number":["2021YFC2400600"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81925035"],"award-info":[{"award-number":["81925035"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018625","name":"Science and Technology Innovation Plan Of Shanghai Science and Technology Commission","doi-asserted-by":"publisher","award":["19431903100"],"award-info":[{"award-number":["19431903100"]}],"id":[{"id":"10.13039\/501100018625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018625","name":"Science and Technology Innovation Plan Of Shanghai Science and Technology Commission","doi-asserted-by":"publisher","award":["18430740800"],"award-info":[{"award-number":["18430740800"]}],"id":[{"id":"10.13039\/501100018625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>\n                    Liposomal technology can enhance drug solubility and stability, achieving codelivery for combination therapy, and modulate the\n                    <jats:italic>in vivo<\/jats:italic>\n                    fate (\n                    <jats:italic>e.g.<\/jats:italic>\n                    , site-specific distribution and controlled release), thereby improving treatment outcomes.\n                  <\/jats:p>","DOI":"10.1039\/d2bm01252a","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T03:58:51Z","timestamp":1668398331000},"page":"62-75","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":77,"title":["Pharmaceutical liposomal delivery\u2014specific considerations of innovation and challenges"],"prefix":"10.1039","volume":"11","author":[{"given":"Taoxing","family":"Peng","sequence":"first","affiliation":[{"name":"State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, China"},{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Rd, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Rd, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Rd, Shanghai 201203, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Ding","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7067-8915","authenticated-orcid":false,"given":"Yongzhuo","family":"Huang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Rd, Shanghai 201203, China"},{"name":"NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Shanghai 201203, China"},{"name":"Zhongshan Institute for Drug Discovery, Institutes of Drug Discovery and Development, Chinese Academy of Sciences, Zhongshan 528437, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D2BM01252A\/cit1\/1","doi-asserted-by":"crossref","first-page":"113884","DOI":"10.1016\/j.addr.2021.113884","volume":"176","author":"Cai","year":"2021","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit2\/1","doi-asserted-by":"crossref","first-page":"100024","DOI":"10.1016\/j.medidd.2020.100024","volume":"6","author":"Wang","year":"2020","journal-title":"Med. Drug Discovery"},{"key":"D2BM01252A\/cit3\/1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jconrel.2012.03.020","volume":"160","author":"Barenholz","year":"2012","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit4\/1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.addr.2012.09.037","volume":"65","author":"Allen","year":"2013","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit5\/1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S1359-0294(00)00090-X","volume":"6","author":"Barenholz","year":"2001","journal-title":"Curr. Opin. Colloid Interface Sci."},{"key":"D2BM01252A\/cit6\/1","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.1038\/s41598-018-22166-3","volume":"8","author":"Alshehri","year":"2018","journal-title":"Sci. Rep."},{"key":"D2BM01252A\/cit7\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3390\/cells7120265","volume":"7","author":"Maroof","year":"2018","journal-title":"Cells"},{"key":"D2BM01252A\/cit8\/1","doi-asserted-by":"crossref","first-page":"107534","DOI":"10.1016\/j.biotechadv.2020.107534","volume":"40","author":"Weng","year":"2020","journal-title":"Biotechnol. Adv."},{"key":"D2BM01252A\/cit9\/1","doi-asserted-by":"crossref","first-page":"16023","DOI":"10.1038\/mtm.2016.23","volume":"3","author":"Chen","year":"2016","journal-title":"Mol. Ther.\u2013Methods Clin. Dev."},{"key":"D2BM01252A\/cit10\/1","doi-asserted-by":"crossref","first-page":"113848","DOI":"10.1016\/j.addr.2021.113848","volume":"178","author":"Brain","year":"2021","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit11\/1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/gt.2017.41","volume":"24","author":"Zylberberg","year":"2017","journal-title":"Gene Ther."},{"key":"D2BM01252A\/cit12\/1","doi-asserted-by":"crossref","first-page":"113851","DOI":"10.1016\/j.addr.2021.113851","volume":"176","author":"Large","year":"2021","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit13\/1","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.3390\/pharmaceutics12111054","volume":"12","author":"Gu","year":"2020","journal-title":"Pharmaceutics"},{"key":"D2BM01252A\/cit14\/1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.addr.2020.06.022","volume":"156","author":"Filipczak","year":"2020","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit15\/1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1556-276X-8-102","volume":"8","author":"Akbarzadeh","year":"2013","journal-title":"Nanoscale Res. Lett."},{"key":"D2BM01252A\/cit16\/1","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1038\/1921197a0","volume":"192","author":"Bangham","year":"1961","journal-title":"Nature"},{"key":"D2BM01252A\/cit17\/1","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0022-2836(64)80115-7","volume":"8","author":"Bangham","year":"1964","journal-title":"J. Mol. Biol."},{"key":"D2BM01252A\/cit18\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-1-4615-7422-4_1","volume-title":"Methods in Membrane Biology","author":"Bangham","year":"1974","unstructured":"A. D.Bangham ,  M. W.Hill  and  N. G. A.Miller , in  Methods in Membrane Biology , ed.  E. D. Korn ,  Springer US ,  Boston, MA ,  1974 , ch. 1, pp.  1\u201368 ,  10.1007\/978-1-4615-7422-4_1"},{"issue":"Suppl B","key":"D2BM01252A\/cit19\/1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/jac\/28.suppl_B.83","volume":"28","author":"Meunier","year":"1991","journal-title":"J. Antimicrob. Chemother."},{"key":"D2BM01252A\/cit20\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/pharmaceutics8020019","volume":"8","author":"Gregoriadis","year":"2016","journal-title":"Pharmaceutics"},{"key":"D2BM01252A\/cit21\/1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3390\/pharmaceutics9020012","volume":"9","author":"Bulbake","year":"2017","journal-title":"Pharmaceutics"},{"key":"D2BM01252A\/cit22\/1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.addr.2020.07.016","volume":"154\u2013155","author":"Jensen","year":"2020","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit23\/1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jconrel.2017.01.025","volume":"249","author":"Dou","year":"2017","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit24\/1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ajps.2013.07.010","volume":"8","author":"Fan","year":"2013","journal-title":"Asian J. Pharm. Sci."},{"key":"D2BM01252A\/cit25\/1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1080\/1061186X.2017.1419361","volume":"26","author":"Ho","year":"2018","journal-title":"J. Drug Targeting"},{"key":"D2BM01252A\/cit26\/1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejpb.2018.09.010","volume":"132","author":"de Matos","year":"2018","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D2BM01252A\/cit27\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.addr.2019.08.003","volume":"143","author":"Wu","year":"2019","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit28\/1","doi-asserted-by":"crossref","first-page":"120358","DOI":"10.1016\/j.talanta.2019.120358","volume":"208","author":"Wang","year":"2020","journal-title":"Talanta"},{"key":"D2BM01252A\/cit29\/1","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.apsb.2021.02.018","volume":"11","author":"Meng","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"D2BM01252A\/cit30\/1","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s40265-016-0538-7","volume":"76","author":"Stone","year":"2016","journal-title":"Drugs"},{"key":"D2BM01252A\/cit31\/1","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1128\/AAC.36.9.1978","volume":"36","author":"Berman","year":"1992","journal-title":"Antimicrob. Agents Chemother."},{"key":"D2BM01252A\/cit32\/1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/1120009X.2017.1306183","volume":"29","author":"Aversa","year":"2017","journal-title":"J. Chemother."},{"key":"D2BM01252A\/cit33\/1","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1128\/AAC.46.3.828-833.2002","volume":"46","author":"Bekersky","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"D2BM01252A\/cit34\/1","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1021\/mp300320d","volume":"9","author":"Jain","year":"2012","journal-title":"Mol. Pharm."},{"key":"D2BM01252A\/cit35\/1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jconrel.2009.09.019","volume":"141","author":"Shimizu","year":"2010","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit36\/1","doi-asserted-by":"crossref","first-page":"e00306-21","DOI":"10.1128\/AAC.00306-21","volume":"65","author":"Herrada","year":"2021","journal-title":"Antimicrob. Agents Chemother."},{"key":"D2BM01252A\/cit37\/1","doi-asserted-by":"crossref","first-page":"S260","DOI":"10.1093\/cid\/ciz076","volume":"68","author":"Groll","year":"2019","journal-title":"Clin. Infect. Dis"},{"key":"D2BM01252A\/cit38\/1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1086\/376634","volume":"37","author":"Ostrosky-Zeichner","year":"2003","journal-title":"Clin. Infect. Dis"},{"key":"D2BM01252A\/cit39\/1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/annonc\/mdh097","volume":"15","author":"O\u2019Brien","year":"2004","journal-title":"Ann. Oncol."},{"key":"D2BM01252A\/cit40\/1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ejpb.2020.06.004","volume":"153","author":"Nagpal","year":"2020","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D2BM01252A\/cit41\/1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0960-9776(01)80005-9","volume":"10","author":"Marty","year":"2001","journal-title":"Breast"},{"key":"D2BM01252A\/cit42\/1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1080\/1061186X.2017.1380655","volume":"26","author":"Kanwal","year":"2018","journal-title":"J. Drug Targeting"},{"key":"D2BM01252A\/cit43\/1","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1200\/JCO.2001.19.5.1444","volume":"19","author":"Batist","year":"2001","journal-title":"J. Clin. Oncol."},{"key":"D2BM01252A\/cit44\/1","doi-asserted-by":"crossref","first-page":"e0185654","DOI":"10.1371\/journal.pone.0185654","volume":"12","author":"Fukuda","year":"2017","journal-title":"PLoS One"},{"key":"D2BM01252A\/cit45\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpharm.2017.01.002","volume":"519","author":"Luo","year":"2017","journal-title":"Int. J. Pharm."},{"key":"D2BM01252A\/cit46\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0960-9776(01)80001-1","volume":"10","author":"Swenson","year":"2001","journal-title":"Breast"},{"key":"D2BM01252A\/cit47\/1","first-page":"3645","volume":"5","author":"Hong","year":"1999","journal-title":"Clin. Cancer Res."},{"key":"D2BM01252A\/cit48\/1","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s40265-017-0741-1","volume":"77","author":"Lamb","year":"2017","journal-title":"Drugs"},{"key":"D2BM01252A\/cit49\/1","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s40265-020-01336-6","volume":"80","author":"Frampton","year":"2020","journal-title":"Drugs"},{"key":"D2BM01252A\/cit50\/1","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1080\/14737140.2016.1174581","volume":"16","author":"Ur Rehman","year":"2016","journal-title":"Expert Rev. Anticancer Ther."},{"key":"D2BM01252A\/cit51\/1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00280-014-2671-x","volume":"75","author":"Chang","year":"2015","journal-title":"Cancer Chemother. Pharmacol."},{"key":"D2BM01252A\/cit52\/1","doi-asserted-by":"crossref","first-page":"e630","DOI":"10.3747\/co.21.1966","volume":"21","author":"Boulanger","year":"2014","journal-title":"Curr. Oncol."},{"key":"D2BM01252A\/cit53\/1","first-page":"190","volume":"25","author":"Chen","year":"2003","journal-title":"Zhonghua Zhongliu Zazhi"},{"key":"D2BM01252A\/cit54\/1","doi-asserted-by":"crossref","first-page":"947","DOI":"10.3892\/mmr.2013.1264","volume":"7","author":"Wang","year":"2013","journal-title":"Mol. Med. Rep."},{"key":"D2BM01252A\/cit55\/1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0169-409X(97)00108-7","volume":"30","author":"Chonn","year":"1998","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit56\/1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1124\/pr.58.3.10","volume":"58","author":"Chou","year":"2006","journal-title":"Pharmacol. Rev."},{"key":"D2BM01252A\/cit57\/1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jconrel.2013.05.041","volume":"170","author":"Yardley","year":"2013","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit58\/1","doi-asserted-by":"crossref","first-page":"9518","DOI":"10.1021\/nn405674m","volume":"7","author":"Ma","year":"2013","journal-title":"ACS Nano"},{"key":"D2BM01252A\/cit59\/1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.leukres.2008.06.028","volume":"33","author":"Tardi","year":"2009","journal-title":"Leuk. Res."},{"key":"D2BM01252A\/cit60\/1","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1200\/JCO.2017.77.6112","volume":"36","author":"Lancet","year":"2018","journal-title":"J. Clin. Oncol."},{"key":"D2BM01252A\/cit61\/1","author":"Pharma","unstructured":"L.Pharma ,  First Patient Enrolled in Phase I Clinical Trial for the First Compound Liposome Formulation in China, Medication Designed to Improve Efficacy and Safety of Combined Chemotherapy ,  https:\/\/www.luye.cn\/lvye_en\/view.php?id=1934 , (accessed July 2022)"},{"key":"D2BM01252A\/cit62\/1","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1007\/s40265-020-01359-z","volume":"80","author":"Bassetti","year":"2020","journal-title":"Drugs"},{"key":"D2BM01252A\/cit63\/1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/jac\/48.3.333","volume":"48","author":"Schiffelers","year":"2001","journal-title":"J. Antimicrob. Chemother."},{"key":"D2BM01252A\/cit64\/1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s40265-019-01095-z","volume":"79","author":"Shirley","year":"2019","journal-title":"Drugs"},{"key":"D2BM01252A\/cit65\/1","doi-asserted-by":"crossref","first-page":"915","DOI":"10.3389\/fmicb.2018.00915","volume":"9","author":"Zhang","year":"2018","journal-title":"Front. Microbiol."},{"key":"D2BM01252A\/cit66\/1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejpb.2021.05.021","volume":"166","author":"Li","year":"2021","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D2BM01252A\/cit67\/1","doi-asserted-by":"crossref","first-page":"120571","DOI":"10.1016\/j.ijpharm.2021.120571","volume":"601","author":"Guimaraes","year":"2021","journal-title":"Int. J. Pharm."},{"key":"D2BM01252A\/cit68\/1","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/annonc\/mdy272.306","volume":"29","author":"Luhn","year":"2018","journal-title":"Ann. Oncol."},{"key":"D2BM01252A\/cit69\/1","doi-asserted-by":"crossref","first-page":"120117","DOI":"10.1016\/j.ijpharm.2020.120117","volume":"593","author":"Makwana","year":"2021","journal-title":"Int. J. Pharm."},{"key":"D2BM01252A\/cit70\/1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/(SICI)1097-0142(19990701)86:1<72::AID-CNCR12>3.0.CO;2-1","volume":"86","author":"Symon","year":"1999","journal-title":"Cancer"},{"key":"D2BM01252A\/cit71\/1","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1186\/s12885-021-08028-8","volume":"21","author":"Liang","year":"2021","journal-title":"BMC Cancer"},{"key":"D2BM01252A\/cit72\/1","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1093\/annonc\/mdl477","volume":"18","author":"Lorusso","year":"2007","journal-title":"Ann. Oncol."},{"key":"D2BM01252A\/cit73\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0168-3659(01)00309-1","volume":"74","author":"Maeda","year":"2001","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit74\/1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijpharm.2003.09.050","volume":"277","author":"Tanaka","year":"2004","journal-title":"Int. J. Pharm."},{"key":"D2BM01252A\/cit75\/1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.addr.2010.04.009","volume":"63","author":"Fang","year":"2011","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit76\/1","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1158\/0008-5472.CAN-12-4561","volume":"73","author":"Prabhakar","year":"2013","journal-title":"Cancer Res."},{"key":"D2BM01252A\/cit77\/1","doi-asserted-by":"crossref","first-page":"120910","DOI":"10.1016\/j.biomaterials.2021.120910","volume":"275","author":"Luan","year":"2021","journal-title":"Biomaterials"},{"key":"D2BM01252A\/cit78\/1","first-page":"294ed7","volume":"7","author":"Wang","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"D2BM01252A\/cit79\/1","doi-asserted-by":"crossref","first-page":"6985","DOI":"10.1021\/acsnano.5b01324","volume":"9","author":"Hansen","year":"2015","journal-title":"ACS Nano"},{"key":"D2BM01252A\/cit80\/1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jconrel.2014.03.057","volume":"190","author":"Nichols","year":"2014","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit81\/1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jconrel.2007.12.017","volume":"126","author":"Ganta","year":"2008","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit82\/1","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.addr.2008.08.005","volume":"60","author":"Byrne","year":"2008","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit83\/1","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/nrd4333","volume":"13","author":"Torchilin","year":"2014","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D2BM01252A\/cit84\/1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jconrel.2011.09.063","volume":"161","author":"Lammers","year":"2012","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit85\/1","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.bbamem.2006.12.013","volume":"1768","author":"Dos Santos","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"D2BM01252A\/cit86\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nrc.2016.108","volume":"17","author":"Shi","year":"2017","journal-title":"Nat. Rev. Cancer"},{"key":"D2BM01252A\/cit87\/1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.addr.2019.04.009","volume":"143","author":"Chen","year":"2019","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit88\/1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.cherd.2019.11.031","volume":"153","author":"Shrimal","year":"2020","journal-title":"Chem. Eng. Res. Des."},{"key":"D2BM01252A\/cit89\/1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.addr.2017.08.003","volume":"128","author":"Liu","year":"2018","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit90\/1","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1016\/j.addr.2013.08.002","volume":"65","author":"Capretto","year":"2013","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2BM01252A\/cit91\/1","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nnano.2012.168","volume":"7","author":"Valencia","year":"2012","journal-title":"Nat. Nanotechnol."},{"key":"D2BM01252A\/cit92\/1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jconrel.2021.03.019","volume":"333","author":"Forigua","year":"2021","journal-title":"J. Controlled Release"},{"key":"D2BM01252A\/cit93\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3390\/vaccines9010065","volume":"9","author":"Buschmann","year":"2021","journal-title":"Vaccines"},{"key":"D2BM01252A\/cit94\/1","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.1021\/nl301253v","volume":"12","author":"Kim","year":"2012","journal-title":"Nano Lett."},{"key":"D2BM01252A\/cit95\/1","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1002\/adma.201405408","volume":"27","author":"Liu","year":"2015","journal-title":"Adv. Mater."},{"key":"D2BM01252A\/cit96\/1","doi-asserted-by":"crossref","first-page":"5671","DOI":"10.1021\/acs.nanolett.1c01353","volume":"21","author":"Shepherd","year":"2021","journal-title":"Nano Lett."},{"key":"D2BM01252A\/cit97\/1","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.2217\/fon-2017-0607","volume":"14","author":"Tolcher","year":"2018","journal-title":"Future Oncol."},{"key":"D2BM01252A\/cit98\/1","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1093\/annonc\/mdu025","volume":"25","author":"Awada","year":"2014","journal-title":"Ann. Oncol."},{"issue":"suppl. 4","key":"D2BM01252A\/cit99\/1","doi-asserted-by":"crossref","first-page":"iv23","DOI":"10.1093\/annonc\/mdz155.085","volume":"30","author":"Su","year":"2019","journal-title":"Ann. Oncol."},{"key":"D2BM01252A\/cit100\/1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/ijc.20083","volume":"110","author":"Strieth","year":"2004","journal-title":"Int. J. Cancer"},{"key":"D2BM01252A\/cit101\/1","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.1158\/1078-0432.CCR-07-4738","volume":"14","author":"Strieth","year":"2008","journal-title":"Clin. Cancer Res."},{"key":"D2BM01252A\/cit102\/1","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1002\/ijc.23088","volume":"122","author":"Strieth","year":"2008","journal-title":"Int. J. Cancer"},{"key":"D2BM01252A\/cit103\/1","doi-asserted-by":"crossref","first-page":"920","DOI":"10.4161\/cbt.6.6.4207","volume":"6","author":"Eichhorn","year":"2007","journal-title":"Cancer Biol. Ther."},{"key":"D2BM01252A\/cit104\/1","doi-asserted-by":"crossref","first-page":"3819","DOI":"10.2147\/IJN.S139450","volume":"14","author":"Mayer","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"D2BM01252A\/cit105\/1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.20892\/j.issn.2095-3941.2017.0054","volume":"14","author":"Zhang","year":"2017","journal-title":"Cancer Biol. Med."},{"key":"D2BM01252A\/cit106\/1","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/aps.2017.10","volume":"38","author":"Kang","year":"2017","journal-title":"Acta Pharmacol. Sin."},{"key":"D2BM01252A\/cit107\/1","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/s41565-019-0591-y","volume":"14","author":"Akinc","year":"2019","journal-title":"Nat. Nanotechnol."},{"key":"D2BM01252A\/cit108\/1","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1007\/s40265-018-0983-6","volume":"78","author":"Hoy","year":"2018","journal-title":"Drugs"},{"key":"D2BM01252A\/cit109\/1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/nrd2742","volume":"8","author":"Whitehead","year":"2009","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D2BM01252A\/cit110\/1","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/nbt.1602","volume":"28","author":"Semple","year":"2010","journal-title":"Nat. Biotechnol."},{"key":"D2BM01252A\/cit111\/1","doi-asserted-by":"crossref","first-page":"E3351","DOI":"10.1073\/pnas.1720542115","volume":"115","author":"Yanez Arteta","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D2BM01252A\/cit112\/1","doi-asserted-by":"crossref","first-page":"120586","DOI":"10.1016\/j.ijpharm.2021.120586","volume":"601","author":"Schoenmaker","year":"2021","journal-title":"Int. J. Pharm."}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/BM\/D2BM01252A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:36:20Z","timestamp":1782970580000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/11\/1\/62-75\/756258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":112,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12,20]]}},"URL":"https:\/\/doi.org\/10.1039\/d2bm01252a","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}