{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:51:29Z","timestamp":1790646689350,"version":"4.1.0"},"reference-count":36,"publisher":"Royal Society of Chemistry (RSC)","issue":"61","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"am","delay-in-days":546,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-19-CE06-0006-01"],"award-info":[{"award-number":["ANR-19-CE06-0006-01"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Commun."],"abstract":"<jats:p>4-Chloro-iminosydnones are suitable mesoionic dipoles for the bioorthognal release of amide, urea or sulfonamide containing-drugs.<\/jats:p>","DOI":"10.1039\/d2cc02784d","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T02:21:16Z","timestamp":1656642076000},"page":"8500-8503","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Selective chlorination of iminosydnones for fast release of amide, sulfonamide and urea-containing drugs"],"prefix":"10.1039","volume":"58","author":[{"given":"Minghao","family":"Feng","sequence":"first","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9a","family":"Madegard","sequence":"additional","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaux","family":"Riomet","sequence":"additional","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manon","family":"Louis","sequence":"additional","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0546-7537","authenticated-orcid":false,"given":"Pier Alexandre","family":"Champagne","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ, 07102, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3924-8287","authenticated-orcid":false,"given":"Gr\u00e9gory","family":"Pieters","sequence":"additional","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6234-3610","authenticated-orcid":false,"given":"Davide","family":"Audisio","sequence":"additional","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5461-329X","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Taran","sequence":"additional","affiliation":[{"name":"CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), Universit\u00e9 Paris Saclay, SCBM, 91191 Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2CC02784D\/cit1a\/1","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1021\/jm0303812","volume":"47","author":"Ettmayer","year":"2004","journal-title":"J. Med. Chem."},{"key":"D2CC02784D\/cit1b\/1","first-page":"559","volume":"17","author":"Rautio","year":"2018","journal-title":"Nat. Rev."},{"key":"D2CC02784D\/cit2a\/1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.addr.2007.05.013","volume":"59","author":"Stella","year":"2007","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2CC02784D\/cit2b\/1","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.xphs.2015.10.018","volume":"105","author":"Ji","year":"2016","journal-title":"J. Pharm. Sci."},{"key":"D2CC02784D\/cit3\/1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.2174\/1389200033489253","volume":"4","author":"Beaumont","year":"2003","journal-title":"Curr. Drug Metab."},{"key":"D2CC02784D\/cit4a\/1","doi-asserted-by":"crossref","first-page":"3867","DOI":"10.1016\/0006-2952(88)90068-8","volume":"37","author":"Tunek","year":"1988","journal-title":"Biochem. Pharmacol."},{"key":"D2CC02784D\/cit4b\/1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1291\/hypres.18.SupplementI_S211","volume":"18","author":"Yoshikawa","year":"1995","journal-title":"Hypertens. Res."},{"key":"D2CC02784D\/cit4c\/1","doi-asserted-by":"crossref","first-page":"653","DOI":"10.2165\/00003495-199957050-00001","volume":"57","author":"Mitlak","year":"1999","journal-title":"Drugs"},{"key":"D2CC02784D\/cit5\/1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nrd2468","volume":"7","author":"Rautio","year":"2008","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D2CC02784D\/cit6\/1","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.addr.2011.02.002","volume":"63","author":"Mahato","year":"2011","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2CC02784D\/cit7\/1","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1039\/D1CS00451D","volume":"51","author":"Wu","year":"2022","journal-title":"Chem. Soc. Rev."},{"key":"D2CC02784D\/cit8\/1","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1039\/C8CS00395E","volume":"48","author":"Ji","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"D2CC02784D\/cit9a\/1","doi-asserted-by":"crossref","first-page":"3147","DOI":"10.1016\/j.bmcl.2006.03.073","volume":"16","author":"Azoulay","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D2CC02784D\/cit9b\/1","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1021\/bc700394s","volume":"19","author":"van Brakel","year":"2008","journal-title":"Bioconjugate Chem."},{"key":"D2CC02784D\/cit10a\/1","doi-asserted-by":"crossref","first-page":"10536","DOI":"10.1002\/anie.201404547","volume":"53","author":"V\u00e7lker","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit10b\/1","doi-asserted-by":"crossref","first-page":"15906","DOI":"10.1038\/ncomms15906","volume":"8","author":"Miller","year":"2017","journal-title":"Nat. Commun."},{"key":"D2CC02784D\/cit10c\/1","doi-asserted-by":"crossref","first-page":"e202113519","DOI":"10.1002\/anie.202113519","volume":"61","author":"Kon\u010d","year":"2022","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit11a\/1","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1038\/ncomms4277","volume":"5","author":"Weiss","year":"2014","journal-title":"Nat. Commun."},{"key":"D2CC02784D\/cit11b\/1","doi-asserted-by":"crossref","first-page":"5395","DOI":"10.1021\/jm500531z","volume":"57","author":"Weiss","year":"2014","journal-title":"J. Med. Chem."},{"key":"D2CC02784D\/cit12\/1","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.1039\/C7CS00184C","volume":"46","author":"Oliveira","year":"2017","journal-title":"Chem. Soc. Rev."},{"key":"D2CC02784D\/cit13\/1","doi-asserted-by":"crossref","first-page":"14112","DOI":"10.1002\/anie.201305969","volume":"52","author":"Versteegen","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit14\/1","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1021\/jacs.7b11217","volume":"140","author":"Carlson","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"D2CC02784D\/cit15\/1","doi-asserted-by":"crossref","first-page":"10955","DOI":"10.1021\/jacs.0c00531","volume":"142","author":"Van Onzen","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"D2CC02784D\/cit16\/1","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1039\/D0SC06099B","volume":"12","author":"Wu","year":"2021","journal-title":"Chem. Sci."},{"key":"D2CC02784D\/cit17\/1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/anie.201609607","volume":"56","author":"Jimenez-Moreno","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit18\/1","doi-asserted-by":"crossref","first-page":"10494","DOI":"10.1002\/anie.201800402","volume":"57","author":"Versteegen","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit19\/1","doi-asserted-by":"crossref","first-page":"15612","DOI":"10.1002\/anie.201708790","volume":"56","author":"Bernard","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit20\/1","doi-asserted-by":"crossref","first-page":"14089","DOI":"10.1039\/C8CC08533A","volume":"54","author":"Shao","year":"2018","journal-title":"Chem. Commun."},{"key":"D2CC02784D\/cit21a\/1","doi-asserted-by":"crossref","first-page":"9376","DOI":"10.1039\/C4CC03816A","volume":"50","author":"Plougastel","year":"2014","journal-title":"Chem. Commun."},{"key":"D2CC02784D\/cit21b\/1","doi-asserted-by":"crossref","first-page":"12073","DOI":"10.1002\/anie.201606495","volume":"55","author":"Liu","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2CC02784D\/cit22\/1","doi-asserted-by":"crossref","first-page":"5082","DOI":"10.1039\/C8CC02128G","volume":"54","author":"Tao","year":"2018","journal-title":"Chem. Commun."},{"key":"D2CC02784D\/cit23\/1","doi-asserted-by":"crossref","first-page":"8535","DOI":"10.1002\/chem.201801163","volume":"34","author":"Riomet","year":"2018","journal-title":"Chem. \u2013 Eur. J."},{"key":"D2CC02784D\/cit24\/1","doi-asserted-by":"crossref","first-page":"6908","DOI":"10.1021\/ja5031744","volume":"136","author":"Rodriguez","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"D2CC02784D\/cit25\/1","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1021\/acs.orglett.0c00600","volume":"22","author":"Riomet","year":"2020","journal-title":"Org. Lett."},{"key":"D2CC02784D\/cit26a\/1","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1039\/C5SC03259H","volume":"7","author":"Narayanam","year":"2016","journal-title":"Chem. Sci."},{"key":"D2CC02784D\/cit26b\/1","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1021\/jacsau.1c00084","volume":"6","author":"Yen-Pon","year":"2021","journal-title":"JACS Au"}],"container-title":["Chemical Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/CC\/D2CC02784D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:15:07Z","timestamp":1782886507000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cc\/article\/58\/61\/8500-8503\/757716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":36,"journal-issue":{"issue":"61","published-print":{"date-parts":[[2022,7,28]]}},"URL":"https:\/\/doi.org\/10.1039\/d2cc02784d","relation":{},"ISSN":["1359-7345","1364-548X"],"issn-type":[{"value":"1359-7345","type":"print"},{"value":"1364-548X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}