{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:51:25Z","timestamp":1782967885603,"version":"3.54.5"},"reference-count":55,"publisher":"Royal Society of Chemistry (RSC)","issue":"35","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"am","delay-in-days":586,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100003968","name":"Iran National Science Foundation","doi-asserted-by":"publisher","award":["92013461"],"award-info":[{"award-number":["92013461"]}],"id":[{"id":"10.13039\/501100003968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Phys. Chem. Chem. Phys."],"abstract":"<jats:p>\n                    We present a new water-dependent molecular mechanism for the widely-used protein stabilizing osmolyte, trimethylamine\n                    <jats:italic>N<\/jats:italic>\n                    -oxide (TMAO), whose mode of action has remained controversial.\n                  <\/jats:p>","DOI":"10.1039\/d2cp01279k","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T09:41:01Z","timestamp":1660124461000},"page":"21178-21187","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The protein-stabilizing effects of TMAO in aqueous and non-aqueous conditions"],"prefix":"10.1039","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0662-3140","authenticated-orcid":false,"given":"Hassan","family":"Monhemi","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Neyshabur, Neyshabur, Iran"},{"name":"Research and Technology Center of Biomolecules, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0376-5597","authenticated-orcid":false,"given":"Hai Nam","family":"Hoang","sequence":"additional","affiliation":[{"name":"Department of Food Technology, Faculty of Chemical Engineering, Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam"},{"name":"Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daron M.","family":"Standley","sequence":"additional","affiliation":[{"name":"Laboratory of Systems Immunology, WPI Immunology Frontier Research Center Osaka University, Osaka 565\u20130871, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8934-8198","authenticated-orcid":false,"given":"Tomoko","family":"Matsuda","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5189-9947","authenticated-orcid":false,"given":"Mohammad Reza","family":"Housaindokht","sequence":"additional","affiliation":[{"name":"Research and Technology Center of Biomolecules, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2CP01279K\/cit1\/1","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1126\/science.7112124","volume":"217","author":"Yancey","year":"1982","journal-title":"Science"},{"key":"D2CP01279K\/cit2\/1","doi-asserted-by":"crossref","first-page":"13997","DOI":"10.1073\/pnas.0606236103","volume":"103","author":"Street","year":"2006","journal-title":"Proc. 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