{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:04:50Z","timestamp":1782965090836,"version":"3.54.5"},"reference-count":55,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"am","delay-in-days":458,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100003086","name":"Eusko Jaurlaritza","doi-asserted-by":"publisher","award":["IT1254-19"],"award-info":[{"award-number":["IT1254-19"]}],"id":[{"id":"10.13039\/501100003086","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","doi-asserted-by":"publisher","award":["PGC2018-097529-B-100"],"award-info":[{"award-number":["PGC2018-097529-B-100"]}],"id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Dalton Trans."],"abstract":"<jats:p>\n                    Iron(\n                    <jats:sc>iii<\/jats:sc>\n                    ) complexes are a promising alternative to the currently used platinum complexes with high hazards and environmental risks. Iron(\n                    <jats:sc>iii<\/jats:sc>\n                    ) complexes bind to the phosphates of DNA by the ligand displacement mechanism and inhibit polymerization.\n                  <\/jats:p>","DOI":"10.1039\/d2dt00111j","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T07:46:41Z","timestamp":1649058401000},"page":"6254-6263","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Study of the DNA binding mechanism and\n                    <i>in vitro<\/i>\n                    activity against cancer cells of iron(\n                    <scp>iii<\/scp>\n                    ) and aluminium(\n                    <scp>iii<\/scp>\n                    ) kojic acid derivative complexes"],"prefix":"10.1039","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4644-761X","authenticated-orcid":false,"given":"Joanna I.","family":"Lachowicz","sequence":"first","affiliation":[{"name":"University of Cagliari, Department of Medical Sciences and Public Health, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Mateddu","sequence":"additional","affiliation":[{"name":"University of Cagliari, Department of Medical Sciences and Public Health, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Coni","sequence":"additional","affiliation":[{"name":"University of Cagliari, Department of Medical Sciences and Public Health, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4302-0234","authenticated-orcid":false,"given":"Claudia","family":"Caltagirone","sequence":"additional","affiliation":[{"name":"University of Cagliari, Department of Chemical and Geological Science, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9986-0638","authenticated-orcid":false,"given":"Sergio","family":"Murgia","sequence":"additional","affiliation":[{"name":"Department of Life and Environmental Sciences, University of Cagliari, via Ospedale 72, Cagliari I-09124, Italy"},{"name":"CSGI, Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Via della Lastruccia 3, I-50019 Sesto Fiorentino, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-4018","authenticated-orcid":false,"given":"Dan","family":"Gibson","sequence":"additional","affiliation":[{"name":"Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, 91120 Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9652-9659","authenticated-orcid":false,"given":"Gabriele","family":"dalla Torre","sequence":"additional","affiliation":[{"name":"Donostia International Physics Centre (DIPC), PK 1072, 20080 Donostia, Euskadi, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xabier","family":"Lopez","sequence":"additional","affiliation":[{"name":"Donostia International Physics Centre (DIPC), PK 1072, 20080 Donostia, Euskadi, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Meloni","sequence":"additional","affiliation":[{"name":"University of Cagliari, Department of Medical Sciences and Public Health, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppina","family":"Pichiri","sequence":"additional","affiliation":[{"name":"University of Cagliari, Department of Medical Sciences and Public Health, Cittadella Universitaria, 09042 Monserrato-Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2DT00111J\/cit1\/1","doi-asserted-by":"crossref","first-page":"12888","DOI":"10.1039\/D0SC04082G","volume":"11","author":"Anthony","year":"2020","journal-title":"Chem. Sci."},{"key":"D2DT00111J\/cit2\/1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2174\/0929867324666170330091438","volume":"25","author":"Faa","year":"2018","journal-title":"Curr. Med. Chem."},{"key":"D2DT00111J\/cit3\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ica.2016.01.006","volume":"444","author":"Zaki","year":"2016","journal-title":"Inorg. Chim. Acta"},{"key":"D2DT00111J\/cit4\/1","doi-asserted-by":"crossref","first-page":"9100","DOI":"10.1074\/jbc.M210284200","volume":"278","author":"Mandic","year":"2003","journal-title":"J. Biol. Chem."},{"key":"D2DT00111J\/cit5\/1","doi-asserted-by":"crossref","first-page":"8818","DOI":"10.1039\/C5CS00134J","volume":"44","author":"Bergamo","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"D2DT00111J\/cit6\/1","doi-asserted-by":"crossref","first-page":"114953","DOI":"10.1016\/j.watres.2019.114953","volume":"164","author":"Mi\u0161\u00edk","year":"2019","journal-title":"Water Res."},{"key":"D2DT00111J\/cit7\/1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.2147\/DDDT.S119488","volume":"11","author":"Ndagi","year":"2017","journal-title":"Drug Des., Dev. Ther."},{"key":"D2DT00111J\/cit8\/1","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.2174\/138161210791209009","volume":"16","author":"Frezza","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"D2DT00111J\/cit9\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/B978-0-12-818429-5.00010-7","volume-title":"Synthetic Inorganic Chemistry","author":"Valente","year":"2021","unstructured":"A.Valente ,  T. S.Morais ,  R. G.Teixeira ,  C. P.Matos ,  A. I.Tomaz  and  M. H.Garcia ,  Synthetic Inorganic Chemistry ,  Elsevier ,  2021 , pp.  223\u2013276"},{"key":"D2DT00111J\/cit10\/1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.2174\/0929867323666160824162546","volume":"24","author":"Esteban Leon","year":"2017","journal-title":"Curr. Med. Chem."},{"key":"D2DT00111J\/cit11\/1","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1039\/D0QI01463J","volume":"8","author":"Liao","year":"2021","journal-title":"Inorg. Chem. Front."},{"issue":"16","key":"D2DT00111J\/cit12\/1","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.3390\/molecules26164730","volume":"26","author":"Abdelrahman","year":"2021","journal-title":"Molecules"},{"key":"D2DT00111J\/cit13\/1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.msec.2018.04.052","volume":"90","author":"Vasantha","year":"2018","journal-title":"Mater. Sci. Eng., C"},{"key":"D2DT00111J\/cit14\/1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0020-1693(00)81143-3","volume":"136","author":"Abu-El-Wafa","year":"1987","journal-title":"Inorg. Chim. Acta"},{"key":"D2DT00111J\/cit15\/1","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.molliq.2015.10.041","volume":"212","author":"Shoair","year":"2015","journal-title":"J. Mol. Liq."},{"issue":"1","key":"D2DT00111J\/cit16\/1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1006\/rtph.2000.1442","volume":"33","author":"Burdock","year":"2001","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"D2DT00111J\/cit17\/1","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jinorgbio.2010.01.007","volume":"104","author":"Nurchi","year":"2010","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit18\/1","doi-asserted-by":"crossref","first-page":"5984","DOI":"10.1039\/c1dt00005e","volume":"40","author":"Nurchi","year":"2011","journal-title":"Dalton Trans."},{"key":"D2DT00111J\/cit19\/1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jinorgbio.2014.09.002","volume":"141","author":"Nurchi","year":"2014","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit20\/1","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jinorgbio.2019.01.012","volume":"193","author":"Nurchi","year":"2019","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit21\/1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jinorgbio.2013.06.009","volume":"127","author":"Toso","year":"2013","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit22\/1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jinorgbio.2015.07.001","volume":"151","author":"Lachowicz","year":"2015","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit23\/1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jinorgbio.2015.08.011","volume":"151","author":"Lachowicz","year":"2015","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit24\/1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jinorgbio.2015.01.016","volume":"148","author":"Peana","year":"2015","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit25\/1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jinorgbio.2018.09.013","volume":"189","author":"Nurchi","year":"2018","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit26\/1","doi-asserted-by":"crossref","first-page":"111520","DOI":"10.1016\/j.jinorgbio.2021.111520","volume":"222","author":"Lachowicz","year":"2021","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit27\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/02603598808048670","volume":"8","author":"Crumbliss","year":"1988","journal-title":"Comments Inorg. Chem."},{"key":"D2DT00111J\/cit28\/1","doi-asserted-by":"crossref","first-page":"111520","DOI":"10.1016\/j.jinorgbio.2021.111520","volume":"222","author":"Lachowicza","year":"2021","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit29\/1","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1039\/J19670001205","author":"Alner","year":"1967","journal-title":"J. Chem. Soc. A"},{"key":"D2DT00111J\/cit30\/1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.jinorgbio.2005.02.010","volume":"99","author":"Wu","year":"2005","journal-title":"J. Inorg. Biochem."},{"key":"D2DT00111J\/cit31\/1","doi-asserted-by":"crossref","first-page":"5991","DOI":"10.1021\/bi00567a008","volume":"19","author":"Karlik","year":"1980","journal-title":"Biochemistry"},{"key":"D2DT00111J\/cit32\/1","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.3748\/wjg.v24.i10.1072","volume":"24","author":"Cesna","year":"2018","journal-title":"World J. Gastroenterol."},{"key":"D2DT00111J\/cit33\/1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s10863-018-9764-x","volume":"50","author":"Trumbeckaite","year":"2018","journal-title":"J. Bioenerg. Biomembr."},{"key":"D2DT00111J\/cit34\/1","doi-asserted-by":"crossref","first-page":"e0152652","DOI":"10.1371\/journal.pone.0152652","volume":"11","author":"Leong","year":"2016","journal-title":"PLoS One"},{"key":"D2DT00111J\/cit35\/1","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/j.ejso.2018.05.020","volume":"44","author":"Ametsbichler","year":"2018","journal-title":"Eur. J. Surg. Oncol."},{"key":"D2DT00111J\/cit36\/1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1001\/archotol.1994.01880290051009","volume":"120","author":"Blakley","year":"1994","journal-title":"Arch. Otolaryngol., Head Neck Surg."},{"key":"D2DT00111J\/cit37\/1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s004200050209","volume":"70","author":"Nygren","year":"1997","journal-title":"Int. Arch. Occup. Environ. Health"},{"key":"D2DT00111J\/cit38\/1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4103\/2230-973X.96920","volume":"2","author":"Tiwari","year":"2012","journal-title":"Int. J. Pharm. Invest."},{"key":"D2DT00111J\/cit39\/1","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1021\/ja00194a035","volume":"111","author":"Chang","year":"1989","journal-title":"J. Am. Chem. Soc."},{"issue":"45","key":"D2DT00111J\/cit40\/1","doi-asserted-by":"crossref","first-page":"11225","DOI":"10.1021\/ja9621760","volume":"118","author":"Jorgensen","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"D2DT00111J\/cit41\/1","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/jcc.540080710","volume":"8","author":"Ponder","year":"1987","journal-title":"J. Comput. Chem."},{"key":"D2DT00111J\/cit42\/1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.cplett.2004.06.011","volume":"393","author":"Yanai","year":"2004","journal-title":"Chem. Phys. Lett."},{"key":"D2DT00111J\/cit43\/1","doi-asserted-by":"crossref","first-page":"6378","DOI":"10.1021\/jp810292n","volume":"113","author":"Marenich","year":"2009","journal-title":"J. Phys. Chem. B"},{"key":"D2DT00111J\/cit44\/1","volume-title":"Handbook of Biochemistry and Molecular Biology","author":"Jencks","year":"2010","unstructured":"W. P.Jencks  and  J.Regenstein ,  Handbook of Biochemistry and Molecular Biology ,  CRC Press , 4th edn,  2010 , pp. 595\u2013635"},{"key":"D2DT00111J\/cit45\/1","doi-asserted-by":"crossref","first-page":"5648","DOI":"10.1063\/1.464913","volume":"98","author":"Becke","year":"1993","journal-title":"J. Chem. Phys."},{"key":"D2DT00111J\/cit46\/1","doi-asserted-by":"crossref","first-page":"11623","DOI":"10.1021\/j100096a001","volume":"98","author":"Stephens","year":"1994","journal-title":"J. Phys. Chem."},{"key":"D2DT00111J\/cit47\/1","doi-asserted-by":"crossref","first-page":"154104","DOI":"10.1063\/1.3382344","volume":"132","author":"Grimme","year":"2010","journal-title":"J. Chem. Phys."},{"key":"D2DT00111J\/cit48\/1","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1021\/cr9904009","volume":"105","author":"Tomasi","year":"2005","journal-title":"Chem. Rev."},{"key":"D2DT00111J\/cit50\/1","doi-asserted-by":"crossref","first-page":"7852","DOI":"10.1039\/c0cp02319a","volume":"13","author":"Al\u00ed-Torres","year":"2011","journal-title":"Phys. Chem. Chem. Phys."},{"key":"D2DT00111J\/cit51\/1","doi-asserted-by":"crossref","first-page":"6003","DOI":"10.1039\/C8DT04216K","volume":"48","author":"Dalla Torre","year":"2019","journal-title":"Dalton Trans."},{"key":"D2DT00111J\/cit52\/1","doi-asserted-by":"crossref","first-page":"3692","DOI":"10.1021\/jp049914o","volume":"108","author":"Palascak","year":"2004","journal-title":"J. Phys. Chem. A"},{"key":"D2DT00111J\/cit53\/1","doi-asserted-by":"crossref","first-page":"5984","DOI":"10.1039\/c1dt00005e","volume":"40","author":"Nurchi","year":"2011","journal-title":"Dalton Trans."},{"key":"D2DT00111J\/cit54\/1","doi-asserted-by":"crossref","first-page":"9216","DOI":"10.1021\/jp902970n","volume":"113","author":"Murgia","year":"2009","journal-title":"J. Phys. Chem. B"},{"key":"D2DT00111J\/cit55\/1","first-page":"506","volume":"10","author":"Walsh","year":"1991","journal-title":"BioTechniques"},{"key":"D2DT00111J\/cit56\/1","doi-asserted-by":"crossref","first-page":"10336","DOI":"10.1039\/C9NJ01548E","volume":"43","author":"Lachowicz","year":"2019","journal-title":"New J. Chem."}],"container-title":["Dalton Transactions"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/DT\/D2DT00111J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:35:24Z","timestamp":1782963324000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/dt\/article\/51\/16\/6254-6263\/764936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":55,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2022,4,20]]}},"URL":"https:\/\/doi.org\/10.1039\/d2dt00111j","relation":{},"ISSN":["1477-9226","1477-9234"],"issn-type":[{"value":"1477-9226","type":"print"},{"value":"1477-9234","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}