{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:29:37Z","timestamp":1789662577241,"version":"4.0.1"},"reference-count":41,"publisher":"Royal Society of Chemistry (RSC)","issue":"22","license":[{"start":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T00:00:00Z","timestamp":1697241600000},"content-version":"am","delay-in-days":651,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2452019181"],"award-info":[{"award-number":["2452019181"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>Non-alcoholic fatty liver disease (NAFLD) has become a public health burden.<\/jats:p>","DOI":"10.1039\/d2fo01167k","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T03:21:31Z","timestamp":1665717691000},"page":"11664-11675","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Highland barley \u03b2-glucan alleviated western diet-induced non-alcoholic fatty liver disease\n                    <i>via<\/i>\n                    increasing energy expenditure and regulating bile acid metabolism in mice"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6552-9499","authenticated-orcid":false,"given":"Huicui","family":"Liu","sequence":"first","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanli","family":"Sun","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxi","family":"Nie","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Xie","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojin","family":"Yuan","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyu","family":"Ma","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5343-8151","authenticated-orcid":false,"given":"Min","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifei","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzhong","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, Shaanxi Province 710062, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juxiu","family":"Li","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi Province 712100, People's Republic of China"},{"name":"Engineering Research Center of Grain and Oil Functionalized Processing, Universities of Shaanxi Province, 712100, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2FO01167K\/cit1\/1","first-page":"1","volume":"65","author":"Xiong","year":"2021","journal-title":"Mol. Nutr. Food Res."},{"key":"D2FO01167K\/cit2\/1","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1002\/hep.30251","volume":"69","author":"Younossi","year":"2019","journal-title":"Hepatology"},{"key":"D2FO01167K\/cit3\/1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jhep.2015.02.025","volume":"62","author":"Karlsen","year":"2015","journal-title":"J. Hepatol."},{"key":"D2FO01167K\/cit4\/1","first-page":"936","volume":"31","author":"Ballestri","year":"2016","journal-title":"Hepatology"},{"key":"D2FO01167K\/cit5\/1","doi-asserted-by":"crossref","first-page":"4733","DOI":"10.1074\/jbc.RA119.011913","volume":"295","author":"Takahashi","year":"2020","journal-title":"J. Biol. Chem."},{"key":"D2FO01167K\/cit6\/1","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/hep.31518","volume":"73","author":"Tilg","year":"2021","journal-title":"Hepatology"},{"key":"D2FO01167K\/cit7\/1","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1039\/C7FO00290D","volume":"8","author":"Li","year":"2017","journal-title":"Food Funct."},{"key":"D2FO01167K\/cit8\/1","first-page":"1","volume":"2016","author":"Wang","year":"2016","journal-title":"Evidence-Based Complementary Altern. Med."},{"key":"D2FO01167K\/cit9\/1","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1053\/j.gastro.2017.01.055","volume":"152","author":"Ch\u00e1vez-Talavera","year":"2017","journal-title":"Gastroenterology"},{"key":"D2FO01167K\/cit10\/1","first-page":"1","volume":"11","author":"Mouzaki","year":"2016","journal-title":"PLoS One"},{"key":"D2FO01167K\/cit11\/1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/hep.28709","volume":"65","author":"Arab","year":"2017","journal-title":"Hepatology"},{"key":"D2FO01167K\/cit12\/1","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1126\/science.284.5418.1362","volume":"284","author":"Makishima","year":"1999","journal-title":"Science"},{"key":"D2FO01167K\/cit13\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.cmet.2016.05.005","volume":"24","author":"Wahlstr\u00f6m","year":"2016","journal-title":"Cell Metab."},{"key":"D2FO01167K\/cit14\/1","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1146\/annurev-pharmtox-010715-103209","volume":"56","author":"Rudraiah","year":"2016","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"D2FO01167K\/cit15\/1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1152\/physrev.00010.2008","volume":"89","author":"Lefebvre","year":"2009","journal-title":"Physiol. Rev."},{"key":"D2FO01167K\/cit16\/1","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.apsb.2021.03.038","volume":"11","author":"Ding","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"D2FO01167K\/cit17\/1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/nature04330","volume":"439","author":"Watanabe","year":"2006","journal-title":"Nature"},{"key":"D2FO01167K\/cit18\/1","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.jhep.2010.12.004","volume":"54","author":"Pols","year":"2011","journal-title":"J. Hepatol."},{"key":"D2FO01167K\/cit19\/1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1172\/JCI76738","volume":"125","author":"Jiang","year":"2015","journal-title":"J. Clin. Invest."},{"key":"D2FO01167K\/cit20\/1","first-page":"1","volume":"10","author":"Kuang","year":"2020","journal-title":"Metabolites"},{"key":"D2FO01167K\/cit21\/1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jcs.2015.06.006","volume":"65","author":"Zhu","year":"2015","journal-title":"J. Cereal Sci."},{"key":"D2FO01167K\/cit22\/1","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1021\/acs.jafc.6b05641","volume":"65","author":"Xia","year":"2017","journal-title":"J. Agric. Food Chem."},{"key":"D2FO01167K\/cit23\/1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3945\/ajcn.2010.29174","volume":"92","author":"Wolever","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"D2FO01167K\/cit24\/1","doi-asserted-by":"crossref","first-page":"116034","DOI":"10.1016\/j.carbpol.2020.116034","volume":"236","author":"Marasca","year":"2020","journal-title":"Carbohydr. Polym."},{"key":"D2FO01167K\/cit25\/1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1039\/c0fo00080a","volume":"1","author":"Gunness","year":"2010","journal-title":"Food Funct."},{"key":"D2FO01167K\/cit26\/1","doi-asserted-by":"crossref","first-page":"7000","DOI":"10.1021\/acs.jafc.1c01465","volume":"69","author":"Nie","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"D2FO01167K\/cit27\/1","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1039\/C8FO00157J","volume":"9","author":"Thandapilly","year":"2018","journal-title":"Food Funct."},{"key":"D2FO01167K\/cit28\/1","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1021\/jf902508t","volume":"58","author":"Kim","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"D2FO01167K\/cit29\/1","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1094\/CCHEM-02-11-0014","volume":"88","author":"Sayar","year":"2011","journal-title":"Cereal Chem."},{"key":"D2FO01167K\/cit30\/1","doi-asserted-by":"crossref","first-page":"9287","DOI":"10.1021\/acs.jafc.1c03379","volume":"69","author":"Liu","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"D2FO01167K\/cit31\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40538-021-00212-z","volume":"8","author":"Nie","year":"2021","journal-title":"Chem. Biol. Technol. Agric."},{"key":"D2FO01167K\/cit32\/1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.foodres.2019.04.011","volume":"122","author":"Chen","year":"2019","journal-title":"Food Res. Int."},{"key":"D2FO01167K\/cit33\/1","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1007\/s00394-019-02117-y","volume":"59","author":"Wang","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"D2FO01167K\/cit34\/1","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.cardfail.2017.06.007","volume":"23","author":"Mayerhofer","year":"2017","journal-title":"J. Card. Failure"},{"key":"D2FO01167K\/cit35\/1","first-page":"1","volume":"2011","author":"Chen","year":"2011","journal-title":"Exp. Diabetes Res."},{"key":"D2FO01167K\/cit36\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/cells8111358","volume":"8","author":"Gottlieb","year":"2019","journal-title":"Cells"},{"key":"D2FO01167K\/cit37\/1","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1194\/jlr.M071183","volume":"57","author":"Takahashi","year":"2016","journal-title":"J. Lipid Res."},{"key":"D2FO01167K\/cit38\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1126\/scitranslmed.aaf4823","volume":"8","author":"Rao","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"D2FO01167K\/cit39\/1","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1002\/cphy.c120023","volume":"3","author":"Chiang","year":"2013","journal-title":"Compr. Physiol."},{"key":"D2FO01167K\/cit40\/1","first-page":"269","volume":"166","author":"Cheng","year":"2018","journal-title":"Toxicol. Sci."},{"key":"D2FO01167K\/cit41\/1","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.cmet.2020.11.017","volume":"33","author":"Zheng","year":"2021","journal-title":"Cell Metab."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/FO\/D2FO01167K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:05:29Z","timestamp":1782878729000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/13\/22\/11664-11675\/768887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":41,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2022,11,14]]}},"URL":"https:\/\/doi.org\/10.1039\/d2fo01167k","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}