{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:16:18Z","timestamp":1790198178236,"version":"4.1.0"},"reference-count":53,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":272,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100004890","name":"Wageningen University and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004890","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007702","name":"Institut Penyelidikan dan Kemajuan Pertanian Malaysia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007702","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>Fermented flaxseed improves lignan (SECO) bioaccessibility in the gastrointestinal phase, release and conversion to enterolactone during colon fermentation.<\/jats:p>","DOI":"10.1039\/d2fo02559k","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T07:23:16Z","timestamp":1664522596000},"page":"10737-10747","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["<i>In vitro<\/i>\n                    gastrointestinal bioaccessibility and colonic fermentation of lignans from fresh, fermented, and germinated flaxseed"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5692-3144","authenticated-orcid":false,"given":"Umi Kalsum","family":"Hussain Zaki","sequence":"first","affiliation":[{"name":"Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands"},{"name":"Food Science and Technology Research Centre, Malaysian Agricultural Research and Development Institute (MARDI), Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Fryganas","sequence":"additional","affiliation":[{"name":"Food Quality & Design Department, Wageningen University & Research, Wageningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Trijsburg","sequence":"additional","affiliation":[{"name":"Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith J. M.","family":"Feskens","sequence":"additional","affiliation":[{"name":"Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4705-8210","authenticated-orcid":false,"given":"Edoardo","family":"Capuano","sequence":"additional","affiliation":[{"name":"Food Quality & Design Department, Wageningen University & Research, Wageningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2FO02559K\/cit1\/1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.steroids.2014.06.012","volume":"90","author":"Paterni","year":"2014","journal-title":"Steroids"},{"key":"D2FO02559K\/cit2\/1","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1016\/j.fct.2007.05.017","volume":"45","author":"Hu","year":"2007","journal-title":"Food Chem. Toxicol."},{"key":"D2FO02559K\/cit3\/1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.jff.2017.08.015","volume":"37","author":"Bravo","year":"2017","journal-title":"J. Funct. Foods"},{"key":"D2FO02559K\/cit4\/1","first-page":"2269","volume":"25","author":"Danbara","year":"2005","journal-title":"Anticancer Res."},{"key":"D2FO02559K\/cit5\/1","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1001\/archinte.163.9.1099","volume":"163","author":"Vanharanta","year":"2003","journal-title":"Arch. Intern. Med."},{"key":"D2FO02559K\/cit6\/1","doi-asserted-by":"crossref","first-page":"e0171390","DOI":"10.1371\/journal.pone.0171390","volume":"12","author":"Zhu","year":"2017","journal-title":"PLoS One"},{"key":"D2FO02559K\/cit7\/1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/nure.12114","volume":"72","author":"Bohn","year":"2014","journal-title":"Nutr. Rev."},{"key":"D2FO02559K\/cit8\/1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/1541-4337.12081","volume":"13","author":"Alminger","year":"2014","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"D2FO02559K\/cit9\/1","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1006\/jfca.2000.0932","volume":"13","author":"Meagher","year":"2000","journal-title":"J. Food Compos. Anal."},{"key":"D2FO02559K\/cit10\/1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.jcs.2007.07.006","volume":"46","author":"Katina","year":"2007","journal-title":"J. Cereal Sci."},{"key":"D2FO02559K\/cit11\/1","doi-asserted-by":"crossref","first-page":"11995","DOI":"10.1021\/jf303502h","volume":"60","author":"Moelants","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"D2FO02559K\/cit12\/1","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.3402\/fnr.v53i0.1912","volume":"53","author":"Kamal-Eldin","year":"2009","journal-title":"Food Nutr. Res."},{"key":"D2FO02559K\/cit13\/1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.cofs.2014.11.007","volume":"1","author":"Coda","year":"2015","journal-title":"Curr. Opin. Food Sci."},{"key":"D2FO02559K\/cit14\/1","doi-asserted-by":"crossref","first-page":"102939","DOI":"10.1016\/j.jcs.2020.102939","author":"Makowska","year":"2020","journal-title":"J. Cereal Sci."},{"key":"D2FO02559K\/cit15\/1","doi-asserted-by":"crossref","first-page":"110488","DOI":"10.1016\/j.foodres.2021.110488","volume":"147","author":"Ruiz de la Bastida","year":"2021","journal-title":"Food Res. Int."},{"key":"D2FO02559K\/cit16\/1","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.nutres.2009.09.016","volume":"29","author":"Fern\u00e1ndez-Garc\u00eda","year":"2009","journal-title":"Nutr. Res."},{"key":"D2FO02559K\/cit17\/1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2174\/157340110790909545","volume":"6","author":"Biehler","year":"2010","journal-title":"Curr.\nNutr. Food Sci."},{"key":"D2FO02559K\/cit18\/1","first-page":"129","volume":"12","author":"Widaningrum","year":"2015","journal-title":"Indones. J. Agric. Postharvest Res."},{"issue":"2","key":"D2FO02559K\/cit19\/1","first-page":"139","volume":"16","author":"Emaga","year":"2012","journal-title":"Biotechnol., Agron., Soc. Environ."},{"key":"D2FO02559K\/cit20\/1","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1039\/C3FO60702J","volume":"5","author":"Minekus","year":"2014","journal-title":"Food Funct."},{"key":"D2FO02559K\/cit21\/1","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1080\/10408398.2011.640757","volume":"54","author":"Bourlieu","year":"2014","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D2FO02559K\/cit22\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-22438-y","volume":"8","author":"Poeker","year":"2018","journal-title":"Sci. Rep."},{"key":"D2FO02559K\/cit23\/1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.jff.2015.02.026","volume":"14","author":"Mosele","year":"2015","journal-title":"J. Funct. Foods"},{"key":"D2FO02559K\/cit24\/1","doi-asserted-by":"crossref","first-page":"9342","DOI":"10.1021\/jf051488w","volume":"53","author":"Pe\u00f1alvo","year":"2005","journal-title":"J. Agric. Food Chem."},{"key":"D2FO02559K\/cit25\/1","doi-asserted-by":"crossref","first-page":"4643","DOI":"10.1021\/jf0497556","volume":"52","author":"Milder","year":"2004","journal-title":"J. Agric. Food Chem."},{"key":"D2FO02559K\/cit26\/1","doi-asserted-by":"crossref","first-page":"8343","DOI":"10.1021\/acs.jafc.6b03452","volume":"64","author":"N\u00f8rskov","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"D2FO02559K\/cit27\/1","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1002\/jsfa.6482","volume":"94","author":"Fuentealba","year":"2014","journal-title":"J. Sci. Food Agric."},{"key":"D2FO02559K\/cit28\/1","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1093\/jn\/135.12.2812","volume":"135","author":"Kuijsten","year":"2005","journal-title":"J. Nutr."},{"key":"D2FO02559K\/cit29\/1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ijgfs.2015.01.001","volume":"2","author":"Cantabrana","year":"2015","journal-title":"Int. J. Gastron. Food Sci."},{"key":"D2FO02559K\/cit30\/1","doi-asserted-by":"crossref","first-page":"5782","DOI":"10.3390\/molecules25245782","volume":"25","author":"Starzy\u0144ska-Janiszewska","year":"2020","journal-title":"Molecules"},{"key":"D2FO02559K\/cit31\/1","doi-asserted-by":"crossref","first-page":"101510","DOI":"10.1016\/j.bcab.2020.101510","volume":"23","author":"Janarny","year":"2020","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"D2FO02559K\/cit32\/1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1094\/CCHEM-03-13-0056-R","volume":"91","author":"Zhang","year":"2014","journal-title":"Cereal Chem."},{"key":"D2FO02559K\/cit33\/1","volume-title":"Sprouted grains: Nutritional value, production, and applications","author":"Feng","year":"2018","unstructured":"H.Feng ,  B.Nemzer  and  J. W.Devries ,  Sprouted grains: Nutritional value, production, and applications ,  Elsevier ,  2018"},{"key":"D2FO02559K\/cit34\/1","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1080\/10408398.2011.562060","volume":"53","author":"H\u00fcbner","year":"2013","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D2FO02559K\/cit35\/1","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.3390\/foods11091272","volume":"11","author":"Vilas-Boas","year":"2022","journal-title":"Foods"},{"key":"D2FO02559K\/cit36\/1","doi-asserted-by":"crossref","first-page":"130751","DOI":"10.1016\/j.foodchem.2021.130751","volume":"367","author":"Li","year":"2022","journal-title":"Food Chem."},{"key":"D2FO02559K\/cit37\/1","first-page":"02008","volume":"111","author":"Yeop","year":"2017","journal-title":"FluidsChE"},{"key":"D2FO02559K\/cit38\/1","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1002\/mnfr.200700086","volume":"51","author":"Green","year":"2007","journal-title":"Mol. Nutr. Food Res."},{"key":"D2FO02559K\/cit39\/1","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1111\/j.1365-2621.2010.02254.x","volume":"45","author":"Ryan","year":"2010","journal-title":"Int. J. Food Sci. Technol."},{"key":"D2FO02559K\/cit40\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.foodres.2013.02.024","volume":"52","author":"Alemany","year":"2013","journal-title":"Food Res. Int."},{"key":"D2FO02559K\/cit41\/1","doi-asserted-by":"crossref","first-page":"6369","DOI":"10.1021\/jf300410h","volume":"60","author":"Hole","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"D2FO02559K\/cit42\/1","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1002\/jsfa.10908","volume":"101","author":"Vinco Pimenta","year":"2021","journal-title":"J. Sci. Food Agric."},{"key":"D2FO02559K\/cit43\/1","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1039\/C4FO00477A","volume":"6","author":"Fardet","year":"2015","journal-title":"Food Funct."},{"key":"D2FO02559K\/cit44\/1","doi-asserted-by":"crossref","first-page":"5709","DOI":"10.3390\/molecules25235709","volume":"25","author":"Senizza","year":"2020","journal-title":"Molecules"},{"key":"D2FO02559K\/cit45\/1","doi-asserted-by":"crossref","first-page":"4806","DOI":"10.1021\/jf800101s","volume":"56","author":"Eeckhaut","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"D2FO02559K\/cit46\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1158\/1055-9965.EPI-18-0826","volume":"28","author":"Chang","year":"2019","journal-title":"Cancer Epidemiol., Biomarkers Prev."},{"key":"D2FO02559K\/cit47\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12934-020-01341-0","volume":"19","author":"Corona","year":"2020","journal-title":"Microb. Cell Fact."},{"key":"D2FO02559K\/cit48\/1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1207\/S15327914NC3601_5","volume":"36","author":"Rowland","year":"2000","journal-title":"Nutr. Cancer"},{"key":"D2FO02559K\/cit49\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3390\/molecules24010041","volume":"24","author":"Brito","year":"2018","journal-title":"Molecules"},{"key":"D2FO02559K\/cit50\/1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3390\/antiox10030435","volume":"10","author":"\u00c1vila-G\u00e1lvez","year":"2021","journal-title":"Antioxidants"},{"key":"D2FO02559K\/cit51\/1","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1158\/1055-9965.EPI-14-0262","volume":"24","author":"Hullar","year":"2015","journal-title":"Cancer Epidemiol., Biomarkers Prev."},{"key":"D2FO02559K\/cit52\/1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00253-011-3338-8","volume":"92","author":"Roncaglia","year":"2011","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"D2FO02559K\/cit53\/1","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.3390\/molecules27072340","volume":"27","author":"Consonni","year":"2022","journal-title":"Molecules"}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/FO\/D2FO02559K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:23:15Z","timestamp":1782966195000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/13\/20\/10737-10747\/769179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":53,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2022,10,17]]}},"URL":"https:\/\/doi.org\/10.1039\/d2fo02559k","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}