{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:51:27Z","timestamp":1788454287677,"version":"build-2803163510"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","license":[{"start":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T00:00:00Z","timestamp":1691020800000},"content-version":"vor","delay-in-days":214,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003624","name":"Ministry of Agriculture, Food and Rural Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003624","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>The prevalence of constipation, one of the common gastrointestinal (GI) diseases, has been gradually increasing.<\/jats:p>","DOI":"10.1039\/d2fo04111a","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T04:26:04Z","timestamp":1691036764000},"page":"7615-7630","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of the laxative effects of Korean\n                    <i>Gochujang<\/i>\n                    containing different microbiota on loperamide-induced constipation in ICR mice"],"prefix":"10.1039","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7618-3614","authenticated-orcid":false,"given":"Na-Yeon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Food Science and Human Nutrition Jeonbuk National University, Jeonju 54896, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Ah","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Chungnam National University, Daejeon 34134, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Jong","family":"Yang","sequence":"additional","affiliation":[{"name":"Microbial Institute for Fermentation Industry (MIFI), Sunchang, 56048, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Ji","family":"Jeong","sequence":"additional","affiliation":[{"name":"Microbial Institute for Fermentation Industry (MIFI), Sunchang, 56048, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8180-6214","authenticated-orcid":false,"given":"Anna","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Food Science and Human Nutrition Jeonbuk National University, Jeonju 54896, Korea"},{"name":"K-Food Research Center, Jeonbuk National University, Jeonju 54896, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5579-650X","authenticated-orcid":false,"given":"Youn-Soo","family":"Cha","sequence":"additional","affiliation":[{"name":"Department of Food Science and Human Nutrition Jeonbuk National University, Jeonju 54896, Korea"},{"name":"K-Food Research Center, Jeonbuk National University, Jeonju 54896, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D2FO04111A\/cit1\/1","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S2468-1253(19)30199-2","volume":"4","author":"Schiller","year":"2019","journal-title":"Lancet Gastroenterol Hepatol."},{"key":"D2FO04111A\/cit2\/1","first-page":"1763","author":"Zhao","year":"2021","journal-title":"Front. Pharmacol."},{"key":"D2FO04111A\/cit3\/1","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1053\/j.gastro.2012.10.028","volume":"144","author":"Bharucha","year":"2013","journal-title":"Gastroenterology"},{"key":"D2FO04111A\/cit4\/1","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1056\/NEJMra020995","volume":"349","author":"Lembo","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"D2FO04111A\/cit5\/1","doi-asserted-by":"crossref","first-page":"946","DOI":"10.3390\/ijms20040946","volume":"20","author":"Kim","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"D2FO04111A\/cit6\/1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1136\/gutjnl-2015-309618","volume":"65","author":"Vandeputte","year":"2016","journal-title":"Gut"},{"key":"D2FO04111A\/cit7\/1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1053\/j.gastro.2015.12.023","volume":"150","author":"Quigley","year":"2016","journal-title":"Gastroenterology"},{"key":"D2FO04111A\/cit8\/1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.dld.2005.06.008","volume":"37","author":"Khalif","year":"2005","journal-title":"Dig. Liver Dis."},{"key":"D2FO04111A\/cit9\/1","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1111\/j.1572-0241.2005.00230.x","volume":"100","author":"Barbara","year":"2005","journal-title":"Am. J. Gastroenterol."},{"key":"D2FO04111A\/cit10\/1","first-page":"G368","volume":"280","author":"Husebye","year":"2001","journal-title":"Am. J. Physiol.: Gastrointest. Liver Physiol."},{"key":"D2FO04111A\/cit11\/1","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/0016-5085(94)90526-6","volume":"107","author":"Uribe","year":"1994","journal-title":"Gastroenterology"},{"key":"D2FO04111A\/cit12\/1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.5056\/jnm.2011.17.2.140","volume":"17","author":"Quigley","year":"2011","journal-title":"J. Neurogastroenterol. Motil."},{"key":"D2FO04111A\/cit13\/1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jef.2015.02.002","volume":"2","author":"Shin","year":"2015","journal-title":"J. Ethnic Foods"},{"key":"D2FO04111A\/cit14\/1","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1007\/s10068-011-0197-0","volume":"20","author":"Jang","year":"2011","journal-title":"Food Sci. Biotechnol."},{"key":"D2FO04111A\/cit15\/1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3390\/foods11030375","volume":"11","author":"Ramalingam","year":"2022","journal-title":"Foods"},{"key":"D2FO04111A\/cit16\/1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3390\/foods10020221","volume":"10","author":"Jeong","year":"2021","journal-title":"Foods"},{"key":"D2FO04111A\/cit17\/1","doi-asserted-by":"crossref","first-page":"13168","DOI":"10.1021\/acs.jafc.9b07962","volume":"68","author":"Jeong","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"D2FO04111A\/cit18\/1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.7845\/kjm.2017.6074","volume":"53","author":"Cho","year":"2017","journal-title":"Korean J. Microbiol. Biotechnol."},{"key":"D2FO04111A\/cit19\/1","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s10068-010-0224-6","volume":"19","author":"Kim","year":"2010","journal-title":"Food Sci. Biotechnol."},{"key":"D2FO04111A\/cit20\/1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.foodres.2016.06.015","volume":"87","author":"Shin","year":"2016","journal-title":"Food Res. Int."},{"key":"D2FO04111A\/cit21\/1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1089\/jmf.2006.9.15","volume":"9","author":"Ahn","year":"2006","journal-title":"J. Med. Food"},{"key":"D2FO04111A\/cit22\/1","first-page":"187","volume":"6","author":"Park","year":"2001","journal-title":"Prev. Nutr. Food Sci."},{"key":"D2FO04111A\/cit23\/1","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.3390\/foods10051072","volume":"10","author":"Mahoro","year":"2021","journal-title":"Foods"},{"key":"D2FO04111A\/cit24\/1","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1590\/S0100-879X1999001000018","volume":"32","author":"Silberstein","year":"1999","journal-title":"Braz. J. Med. Biol. Res."},{"key":"D2FO04111A\/cit25\/1","doi-asserted-by":"crossref","first-page":"17095","DOI":"10.1038\/nrdp.2017.95","volume":"3","author":"Camilleri","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"D2FO04111A\/cit26\/1","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.3390\/molecules23113026","volume":"23","author":"Qian","year":"2018","journal-title":"Molecules"},{"issue":"2","key":"D2FO04111A\/cit27\/1","first-page":"649","volume":"41","author":"Yin","year":"2018","journal-title":"Int. J. Mol. Med."},{"key":"D2FO04111A\/cit28\/1","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/S0024-3205(97)00433-5","volume":"61","author":"Ehlert","year":"1997","journal-title":"Life Sci."},{"key":"D2FO04111A\/cit29\/1","doi-asserted-by":"crossref","first-page":"e687","DOI":"10.1111\/nmo.12194","volume":"25","author":"Tanahashi","year":"2013","journal-title":"Neurogastroenterol. Motil."},{"key":"D2FO04111A\/cit30\/1","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1113\/jphysiol.2006.116624","volume":"576","author":"Komuro","year":"2006","journal-title":"J. Physiol."},{"key":"D2FO04111A\/cit31\/1","first-page":"4099","volume":"7","author":"Tan","year":"2014","journal-title":"Int. J. Clin. Exp. Med."},{"key":"D2FO04111A\/cit32\/1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4291\/wjgp.v2.i2.19","volume":"2","author":"Ihara","year":"2011","journal-title":"World J. Gastrointest. Pathophysiol."},{"key":"D2FO04111A\/cit33\/1","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1002\/ptr.5410","volume":"29","author":"Cirillo","year":"2015","journal-title":"Phytother. Res."},{"key":"D2FO04111A\/cit34\/1","doi-asserted-by":"crossref","first-page":"745","DOI":"10.11002\/kjfp.2019.26.7.745","volume":"26","author":"Baek","year":"2019","journal-title":"Korean J. Food Preserv."},{"key":"D2FO04111A\/cit35\/1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/s41564-019-0631-2","volume":"5","author":"Ryu","year":"2020","journal-title":"Nat. Microbiol."},{"key":"D2FO04111A\/cit36\/1","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1046\/j.1365-2036.2001.00982.x","volume":"15","author":"Schiller","year":"2001","journal-title":"Aliment. Pharmacol. Ther."},{"key":"D2FO04111A\/cit37\/1","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.3390\/ijms17071172","volume":"17","author":"Ikarashi","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"D2FO04111A\/cit38\/1","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s13765-014-4106-0","volume":"57","author":"Kim","year":"2014","journal-title":"J. Korean Soc. Appl. Biol. Chem."},{"key":"D2FO04111A\/cit39\/1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/s41598-017-00612-y","volume":"7","author":"Ge","year":"2017","journal-title":"Sci. Rep."},{"key":"D2FO04111A\/cit40\/1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s12934-017-0691-z","volume":"16","author":"LeBlanc","year":"2017","journal-title":"Microb. Cell Fact."},{"key":"D2FO04111A\/cit41\/1","doi-asserted-by":"crossref","first-page":"17095","DOI":"10.1038\/nrdp.2017.95","volume":"3","author":"Camilleri","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"D2FO04111A\/cit42\/1","doi-asserted-by":"crossref","first-page":"666","DOI":"10.3390\/molecules27030666","volume":"27","author":"He","year":"2022","journal-title":"Molecules"},{"key":"D2FO04111A\/cit43\/1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3168\/jds.2018-15206","volume":"102","author":"Zhao","year":"2019","journal-title":"J. Dairy Sci."},{"key":"D2FO04111A\/cit44\/1","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.3892\/etm.2017.4133","volume":"13","author":"Chai","year":"2017","journal-title":"Exp. Ther. Med."},{"key":"D2FO04111A\/cit45\/1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4196\/kjpp.2011.15.3.129","volume":"15","author":"Shahi","year":"2011","journal-title":"Korean J. Physiol. Pharmacol."},{"issue":"4","key":"D2FO04111A\/cit46\/1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.4162\/nrp.2022.16.4.435","volume":"16","author":"Kim","year":"2022","journal-title":"Nutr. Res. Pract."},{"key":"D2FO04111A\/cit47\/1","doi-asserted-by":"crossref","first-page":"3352","DOI":"10.1038\/s41598-021-82866-1","volume":"11","author":"Yu","year":"2021","journal-title":"Sci. Rep."},{"key":"D2FO04111A\/cit48\/1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nature08821","volume":"464","author":"Qin","year":"2010","journal-title":"Nature"},{"key":"D2FO04111A\/cit49\/1","doi-asserted-by":"crossref","first-page":"e0164731","DOI":"10.1371\/journal.pone.0164731","volume":"11","author":"de Meij","year":"2016","journal-title":"PLoS One"},{"key":"D2FO04111A\/cit50\/1","first-page":"151","volume":"18","author":"Pourhoseingholi","year":"2009","journal-title":"J. Gastrointestin Liver Dis."},{"key":"D2FO04111A\/cit51\/1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3390\/ijms20020433","volume":"20","author":"Jalanka","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"D2FO04111A\/cit52\/1","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.3168\/jds.2013-7551","volume":"97","author":"Mani-L\u00f3pez","year":"2014","journal-title":"J. Dairy Sci."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/FO\/D2FO04111A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:26:21Z","timestamp":1782930381000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/14\/16\/7615-7630\/769486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":52,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2023,8,14]]}},"URL":"https:\/\/doi.org\/10.1039\/d2fo04111a","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}