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Res."},{"key":"D2NP00012A\/cit74\/1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0378-5173(98)00338-X","volume":"179","author":"Craig","year":"1999","journal-title":"Int. J. Pharm."},{"key":"D2NP00012A\/cit75\/1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.ejps.2009.04.005","volume":"37","author":"Graeser","year":"2009","journal-title":"Eur. J. Pharm. Sci."},{"key":"D2NP00012A\/cit76\/1","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/jps.20926","volume":"96","author":"Yoshioka","year":"2007","journal-title":"J. Pharm. Sci."},{"key":"D2NP00012A\/cit77\/1","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1111\/cmi.12084","volume":"15","author":"Taylor","year":"2013","journal-title":"Cell. Microbiol."},{"key":"D2NP00012A\/cit78\/1","doi-asserted-by":"crossref","first-page":"e0005156","DOI":"10.1371\/journal.pntd.0005156","volume":"11","author":"Klarmann-Schulz","year":"2017","journal-title":"PLoS Negl. Trop. 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