{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:49:39Z","timestamp":1788536979831,"version":"build-2803163510"},"reference-count":45,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T00:00:00Z","timestamp":1682726400000},"content-version":"am","delay-in-days":483,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["SR\/S2\/JCB-17\/2008"],"award-info":[{"award-number":["SR\/S2\/JCB-17\/2008"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Org. Biomol. Chem."],"abstract":"<jats:p>\n                    An efficient one-pot approach for the enantioselective synthesis of tetrahydrofuran spirooxindoles\n                    <jats:italic>via<\/jats:italic>\n                    domino oxa-Michael\/Michael addition reaction of \u03b3-hydroxyenones to isatylidene malononitriles, using a cinchona derived bifunctional squaramide catalyst has been developed.\n                  <\/jats:p>","DOI":"10.1039\/d2ob00633b","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T02:21:16Z","timestamp":1651198876000},"page":"4155-4160","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Enantioselective synthesis of tetrahydrofuran spirooxindoles\n                    <i>via<\/i>\n                    domino oxa-Michael\/Michael addition reaction using a bifunctional squaramide catalyst"],"prefix":"10.1039","volume":"20","author":[{"given":"Khyati","family":"Shukla","sequence":"first","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur-208 016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Khushboo","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur-208 016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratibha","family":"Mahto","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur-208 016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0928-5543","authenticated-orcid":false,"given":"Vinod K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur-208 016, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2OB00633B\/cit1a\/1","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1021\/acs.accounts.8b00097","volume":"51","author":"Cao","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"D2OB00633B\/cit1b\/1","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1039\/C4MD00469H","volume":"6","author":"Chakraborty","year":"2015","journal-title":"MedChemComm"},{"key":"D2OB00633B\/cit1c\/1","doi-asserted-by":"crossref","first-page":"6607","DOI":"10.1039\/C8CC02364F","volume":"54","author":"Mei","year":"2018","journal-title":"Chem. Commun."},{"key":"D2OB00633B\/cit1d\/1","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1039\/c0md00239a","volume":"2","author":"Rajesh","year":"2011","journal-title":"MedChemComm"},{"key":"D2OB00633B\/cit1e\/1","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1039\/C1CS15156H","volume":"41","author":"Rios","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"D2OB00633B\/cit1f\/1","doi-asserted-by":"crossref","first-page":"6104","DOI":"10.1021\/cr300135y","volume":"112","author":"Singh","year":"2012","journal-title":"Chem. Rev."},{"key":"D2OB00633B\/cit1g\/1","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1021\/acscatal.8b03694","volume":"9","author":"Xu","year":"2019","journal-title":"ACS Catal."},{"key":"D2OB00633B\/cit2a\/1","doi-asserted-by":"crossref","first-page":"3676","DOI":"10.1016\/j.bmcl.2011.04.088","volume":"21","author":"Chowdhury","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D2OB00633B\/cit2b\/1","doi-asserted-by":"crossref","first-page":"3522","DOI":"10.1016\/j.tet.2015.03.050","volume":"71","author":"Ma","year":"2015","journal-title":"Tetrahedron"},{"key":"D2OB00633B\/cit2c\/1","doi-asserted-by":"crossref","first-page":"4967","DOI":"10.1039\/C5OB00256G","volume":"13","author":"Wu","year":"2015","journal-title":"Org. Biomol. Chem."},{"key":"D2OB00633B\/cit2d\/1","doi-asserted-by":"crossref","first-page":"5016","DOI":"10.1021\/ol502307u","volume":"16","author":"Zhou","year":"2014","journal-title":"Org. Lett."},{"key":"D2OB00633B\/cit2e\/1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1021\/ja067552n","volume":"129","author":"Franz","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"D2OB00633B\/cit3b\/1","doi-asserted-by":"crossref","first-page":"805","DOI":"10.3987\/R-1975-10-0805","volume":"3","author":"Hino","year":"1975","journal-title":"Heterocycles"},{"key":"D2OB00633B\/cit3c\/1","doi-asserted-by":"crossref","first-page":"6647","DOI":"10.1039\/C8OB01713A","volume":"16","author":"Jiang","year":"2018","journal-title":"Org. Biomol. Chem."},{"key":"D2OB00633B\/cit3e\/1","doi-asserted-by":"crossref","first-page":"5349","DOI":"10.1016\/S0040-4039(02)00927-9","volume":"43","author":"Nair","year":"2002","journal-title":"Tetrahedron Lett."},{"key":"D2OB00633B\/cit3f\/1","first-page":"949","volume":"58B","author":"Nayak","year":"2019","journal-title":"Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem."},{"key":"D2OB00633B\/cit3g\/1","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1055\/s-2004-832829","author":"Smet","year":"2004","journal-title":"Synlett"},{"key":"D2OB00633B\/cit3h\/1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ajoc.201400016","volume":"3","author":"Zhang","year":"2014","journal-title":"Asian J. Org. Chem."},{"key":"D2OB00633B\/cit4a\/1","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1002\/anie.201105739","volume":"51","author":"Hanhan","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2OB00633B\/cit4b\/1","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.1021\/om400473p","volume":"32","author":"Mei","year":"2013","journal-title":"Organometallics"},{"key":"D2OB00633B\/cit4c\/1","doi-asserted-by":"crossref","first-page":"10980","DOI":"10.1002\/ange.201305870","volume":"125","author":"Silvi","year":"2013","journal-title":"Angew. Chem."},{"key":"D2OB00633B\/cit4d\/1","doi-asserted-by":"crossref","first-page":"3992","DOI":"10.1002\/adsc.201600782","volume":"358","author":"Zhao","year":"2016","journal-title":"Adv. Synth. Catal."},{"key":"D2OB00633B\/cit4e\/1","doi-asserted-by":"crossref","first-page":"4195","DOI":"10.1021\/acs.joc.9b03378","volume":"85","author":"Guo","year":"2020","journal-title":"J. Org. Chem."},{"key":"D2OB00633B\/cit5a\/1","doi-asserted-by":"crossref","first-page":"11718","DOI":"10.1021\/acsomega.8b01271","volume":"3","author":"Chennapuram","year":"2018","journal-title":"ACS Omega"},{"key":"D2OB00633B\/cit5b\/1","doi-asserted-by":"crossref","first-page":"7148","DOI":"10.1016\/j.tet.2018.10.029","volume":"74","author":"Hu","year":"2018","journal-title":"Tetrahedron"},{"key":"D2OB00633B\/cit5c\/1","doi-asserted-by":"crossref","first-page":"8346","DOI":"10.1039\/C6OB01256F","volume":"14","author":"Xie","year":"2016","journal-title":"Org. Biomol. Chem."},{"key":"D2OB00633B\/cit5d\/1","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1039\/c2ob06995d","volume":"10","author":"Yin","year":"2012","journal-title":"Org. Biomol. Chem."},{"key":"D2OB00633B\/cit5e\/1","doi-asserted-by":"crossref","first-page":"7381","DOI":"10.1002\/anie.201501747","volume":"54","author":"Yu","year":"2015","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2OB00633B\/cit5f\/1","doi-asserted-by":"crossref","first-page":"8327","DOI":"10.1016\/j.tet.2016.11.001","volume":"72","author":"Zhu","year":"2016","journal-title":"Tetrahedron"},{"key":"D2OB00633B\/cit6\/1","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1039\/C1CS15167C","volume":"41","author":"Nising","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"D2OB00633B\/cit7a\/1","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1021\/ol3003755","volume":"14","author":"Asano","year":"2012","journal-title":"Org. Lett."},{"key":"D2OB00633B\/cit7b\/1","doi-asserted-by":"crossref","first-page":"16486","DOI":"10.1021\/jacs.6b10660","volume":"138","author":"Liu","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"D2OB00633B\/cit7c\/1","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1002\/ajoc.201800316","volume":"7","author":"Mondal","year":"2018","journal-title":"Asian J. Org. Chem."},{"key":"D2OB00633B\/cit7d\/1","doi-asserted-by":"crossref","first-page":"8645","DOI":"10.1021\/acs.joc.8b00781","volume":"83","author":"Mondal","year":"2018","journal-title":"J. Org. Chem."},{"key":"D2OB00633B\/cit7e\/1","doi-asserted-by":"crossref","first-page":"7101","DOI":"10.1002\/ejoc.201701439","author":"Mondal","year":"2017","journal-title":"Eur. J. Org. Chem."},{"key":"D2OB00633B\/cit7f\/1","doi-asserted-by":"crossref","first-page":"4348","DOI":"10.1002\/adsc.201800900","volume":"360","author":"Mondal","year":"2018","journal-title":"Adv. Synth. Catal."},{"key":"D2OB00633B\/cit7g\/1","doi-asserted-by":"crossref","first-page":"13082","DOI":"10.1021\/acs.joc.1c00644","volume":"86","author":"Parida","year":"2021","journal-title":"J. Org. Chem."},{"key":"D2OB00633B\/cit7h\/1","doi-asserted-by":"crossref","first-page":"6264","DOI":"10.1021\/ol503104b","volume":"16","author":"Yoneda","year":"2014","journal-title":"Org. Lett."},{"key":"D2OB00633B\/cit8a\/1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2174\/157017910790820283","volume":"7","author":"Burke","year":"2010","journal-title":"Curr. Org. Synth."},{"key":"D2OB00633B\/cit8b\/1","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/9783527681020.ch11","volume-title":"Metals and Metal Complexes in Cooperative Catalysis with Enzymes within Organic-Synthetic One-Pot Processes","author":"Groeger","year":"2015","unstructured":"H.Groeger ,  Metals and Metal Complexes in Cooperative Catalysis with Enzymes within Organic-Synthetic One-Pot Processes ,  2015 , ch. 11, pp.  325\u2013349 ,  10.1002\/9783527681020.ch11"},{"key":"D2OB00633B\/cit8c\/1","first-page":"21","volume":"39","author":"Yokoshima","year":"2010","journal-title":"Fain Kemikaru"},{"key":"D2OB00633B\/cit9a\/1","doi-asserted-by":"crossref","first-page":"5962","DOI":"10.1021\/acs.orglett.9b02094","volume":"21","author":"Mahto","year":"2019","journal-title":"Org. Lett."},{"key":"D2OB00633B\/cit9b\/1","doi-asserted-by":"crossref","first-page":"132115","DOI":"10.1016\/j.tet.2021.132115","volume":"87","author":"Mahto","year":"2021","journal-title":"Tetrahedron"},{"key":"D2OB00633B\/cit10a\/1","doi-asserted-by":"crossref","first-page":"5270","DOI":"10.1016\/j.tet.2018.02.002","volume":"74","author":"Rana","year":"2018","journal-title":"Tetrahedron"},{"key":"D2OB00633B\/cit10b\/1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.tetlet.2018.11.064","volume":"60","author":"Shukla","year":"2019","journal-title":"Tetrahedron Lett."}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/OB\/D2OB00633B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:12:15Z","timestamp":1782965535000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ob\/article\/20\/20\/4155-4160\/778483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":45,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2022,5,26]]}},"URL":"https:\/\/doi.org\/10.1039\/d2ob00633b","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}