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Sci."],"abstract":"<jats:p>\n                    Bicyclo[1.1.1]pentanes (BCPs), utilized as sp\n                    <jats:sup>3<\/jats:sup>\n                    -rich bioisosteres for\n                    <jats:italic>tert<\/jats:italic>\n                    -butyl- and aryl groups as well as internal alkynes, have gained considerable momentum in drug development programs.\n                  <\/jats:p>","DOI":"10.1039\/d2sc05100a","type":"journal-article","created":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T11:41:34Z","timestamp":1664797294000},"page":"11936-11942","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["One step synthesis of unsymmetrical 1,3-disubstituted BCP ketones\n                    <i>via<\/i>\n                    nickel\/photoredox-catalyzed [1.1.1]propellane multicomponent dicarbofunctionalization"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7598-7880","authenticated-orcid":false,"given":"Weichen","family":"Huang","sequence":"first","affiliation":[{"name":"Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia 19104-6323, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Keess","sequence":"additional","affiliation":[{"name":"Medicinal Chemistry Department, Neuroscience Discovery Research, AbbVie Deutschland GmbH & Co. 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