{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:22:51Z","timestamp":1792264971013,"version":"4.4.0"},"reference-count":53,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","license":[{"start":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T00:00:00Z","timestamp":1679011200000},"content-version":"am","delay-in-days":440,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51372157"],"award-info":[{"award-number":["51372157"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>\n                    A Cu(\n                    <jats:sc>ii<\/jats:sc>\n                    )-Chelated polydopamine nano-system (Cu\u2013PDA) acts as photothermal agent (PTA), Fenton-like reaction initiator and \u201cimmunogenic cell death\u201d inducer to mediate PTT\/CDT synergistical tumor therapy and antitumor immune activation.\n                  <\/jats:p>","DOI":"10.1039\/d2tb00025c","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T03:01:45Z","timestamp":1647486105000},"page":"3104-3118","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Cu-Chelated polydopamine nanoparticles as a photothermal medium and \u201cimmunogenic cell death\u201d inducer for combined tumor therapy"],"prefix":"10.1039","volume":"10","author":[{"given":"Na","family":"Xu","sequence":"first","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ao","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximing","family":"Pu","sequence":"additional","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Liao","sequence":"additional","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9210-1842","authenticated-orcid":false,"given":"Zhongbing","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9750-443X","authenticated-orcid":false,"given":"Guangfu","family":"Yin","sequence":"additional","affiliation":[{"name":"College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2TB00025C\/cit1\/1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/s41467-017-00424-8","volume":"8","author":"Huo","year":"2017","journal-title":"Nat. Commun."},{"key":"D2TB00025C\/cit2\/1","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1002\/anie.201510031","volume":"55","author":"Zhang","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2TB00025C\/cit3\/1","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/anie.201805664","volume":"58","author":"Tang","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2TB00025C\/cit4\/1","doi-asserted-by":"crossref","first-page":"4056","DOI":"10.1039\/D0TB00248H","volume":"8","author":"Chen","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00025C\/cit5\/1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1021\/jacs.7b11114","volume":"140","author":"Bai","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"D2TB00025C\/cit6\/1","doi-asserted-by":"crossref","first-page":"17902","DOI":"10.1039\/C8NR06507A","volume":"10","author":"Guan","year":"2018","journal-title":"Nanoscale"},{"key":"D2TB00025C\/cit7\/1","doi-asserted-by":"crossref","first-page":"19285","DOI":"10.1021\/acsami.0c02465","volume":"12","author":"Du","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit8\/1","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.apcatb.2012.05.044","volume":"125","author":"Zhao","year":"2012","journal-title":"Appl. Catal., B"},{"key":"D2TB00025C\/cit9\/1","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.biomaterials.2017.06.035","volume":"141","author":"Hu","year":"2017","journal-title":"Biomaterials"},{"key":"D2TB00025C\/cit10\/1","doi-asserted-by":"crossref","first-page":"8629","DOI":"10.1021\/es802274h","volume":"43","author":"Masomboon","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"D2TB00025C\/cit11\/1","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.1039\/C5CS00224A","volume":"44","author":"Kumar","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"D2TB00025C\/cit12\/1","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1038\/nature07733","volume":"458","author":"Diehn","year":"2009","journal-title":"Nature"},{"key":"D2TB00025C\/cit13\/1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1039\/B312445B","volume":"28","author":"Brillas","year":"2004","journal-title":"New J. Chem."},{"key":"D2TB00025C\/cit14\/1","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/j.cej.2016.11.016","volume":"313","author":"Soltani","year":"2017","journal-title":"Chem. Eng. J."},{"key":"D2TB00025C\/cit15\/1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1039\/D0TB02360D","volume":"9","author":"Hao","year":"2021","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00025C\/cit16\/1","doi-asserted-by":"crossref","first-page":"1907954","DOI":"10.1002\/adfm.201907954","volume":"30","author":"Zhong","year":"2019","journal-title":"Adv. Funct. Mater."},{"key":"D2TB00025C\/cit17\/1","doi-asserted-by":"crossref","first-page":"9846","DOI":"10.1002\/anie.201903981","volume":"58","author":"Wang","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2TB00025C\/cit18\/1","doi-asserted-by":"crossref","first-page":"5057","DOI":"10.1021\/cr400407a","volume":"114","author":"Liu","year":"2014","journal-title":"Chem. Rev."},{"key":"D2TB00025C\/cit19\/1","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1002\/adma.201204683","volume":"25","author":"Liu","year":"2013","journal-title":"Adv. Mater."},{"key":"D2TB00025C\/cit20\/1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.biomaterials.2015.11.037","volume":"81","author":"Wang","year":"2016","journal-title":"Biomaterials"},{"key":"D2TB00025C\/cit21\/1","doi-asserted-by":"crossref","first-page":"7327","DOI":"10.1002\/adfm.201503587","volume":"25","author":"Zhong","year":"2015","journal-title":"Adv. Funct. Mater."},{"key":"D2TB00025C\/cit22\/1","doi-asserted-by":"crossref","first-page":"16793","DOI":"10.1021\/acsami.7b01540","volume":"9","author":"Li","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit23\/1","doi-asserted-by":"crossref","first-page":"e1902352","DOI":"10.1002\/smll.201902352","volume":"15","author":"Chen","year":"2019","journal-title":"Small"},{"key":"D2TB00025C\/cit24\/1","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.jconrel.2020.03.007","volume":"321","author":"An","year":"2020","journal-title":"J. Controlled Release"},{"key":"D2TB00025C\/cit25\/1","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1600-0749.2006.00345.x","volume":"19","author":"Meredith","year":"2006","journal-title":"Pigm. Cell Res."},{"key":"D2TB00025C\/cit26\/1","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1021\/am3027635","volume":"5","author":"Luo","year":"2013","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit27\/1","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1016\/j.biomaterials.2009.02.018","volume":"30","author":"Bettinger","year":"2009","journal-title":"Biomaterials"},{"key":"D2TB00025C\/cit28\/1","doi-asserted-by":"crossref","first-page":"3331","DOI":"10.2147\/IJN.S132270","volume":"12","author":"Xi","year":"2017","journal-title":"Int. J. Nanomed."},{"key":"D2TB00025C\/cit29\/1","doi-asserted-by":"crossref","first-page":"17150","DOI":"10.1039\/C6NR05502H","volume":"8","author":"Hu","year":"2016","journal-title":"Nanoscale"},{"key":"D2TB00025C\/cit30\/1","doi-asserted-by":"crossref","first-page":"10186","DOI":"10.1021\/acsnano.6b05502","volume":"10","author":"Li","year":"2016","journal-title":"ACS Nano"},{"key":"D2TB00025C\/cit31\/1","doi-asserted-by":"crossref","first-page":"9265","DOI":"10.1021\/acs.langmuir.6b02331","volume":"32","author":"Ang","year":"2016","journal-title":"Langmuir"},{"key":"D2TB00025C\/cit32\/1","doi-asserted-by":"crossref","first-page":"19706","DOI":"10.1021\/acsami.7b05583","volume":"9","author":"Ge","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit33\/1","doi-asserted-by":"crossref","first-page":"8195","DOI":"10.1021\/acs.chemmater.7b02262","volume":"29","author":"Wang","year":"2017","journal-title":"Chem. Mater."},{"key":"D2TB00025C\/cit34\/1","doi-asserted-by":"crossref","first-page":"18133","DOI":"10.1021\/acsami.9b02905","volume":"11","author":"Chen","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit35\/1","first-page":"2643","volume":"13","author":"Huo","year":"2019","journal-title":"ACS Nano"},{"key":"D2TB00025C\/cit36\/1","doi-asserted-by":"crossref","first-page":"31735","DOI":"10.1021\/acsami.9b11291","volume":"11","author":"Nie","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit37\/1","doi-asserted-by":"crossref","first-page":"6174","DOI":"10.1021\/acs.chemmater.9b01958","volume":"31","author":"Wang","year":"2019","journal-title":"Chem. Mater."},{"key":"D2TB00025C\/cit38\/1","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1021\/acsnano.6b06658","volume":"11","author":"Chen","year":"2017","journal-title":"ACS Nano"},{"key":"D2TB00025C\/cit39\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2018.02.041","volume":"165","author":"Sheng","year":"2018","journal-title":"Biomaterials"},{"key":"D2TB00025C\/cit40\/1","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1158\/1078-0432.CCR-09-2891","volume":"16","author":"Zitvogel","year":"2010","journal-title":"Clin. Cancer Res."},{"key":"D2TB00025C\/cit41\/1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.cytogfr.2013.01.005","volume":"24","author":"Dudek","year":"2013","journal-title":"Cytokine Growth Factor Rev."},{"key":"D2TB00025C\/cit42\/1","doi-asserted-by":"crossref","first-page":"8281","DOI":"10.1016\/S0040-4020(97)00494-8","volume":"53","author":"Pezzella","year":"1997","journal-title":"Tetrahedron"},{"key":"D2TB00025C\/cit43\/1","doi-asserted-by":"crossref","first-page":"5057","DOI":"10.1021\/cr400407a","volume":"114","author":"Liu","year":"2014","journal-title":"Chem. Rev."},{"key":"D2TB00025C\/cit44\/1","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1021\/acsami.7b16222","volume":"10","author":"Zhao","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00025C\/cit45\/1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1039\/C5TB01924A","volume":"4","author":"Su","year":"2016","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00025C\/cit46\/1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.canlet.2010.10.014","volume":"332","author":"Jego","year":"2013","journal-title":"Cancer Lett."},{"key":"D2TB00025C\/cit47\/1","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.tips.2016.11.009","volume":"38","author":"Wu","year":"2017","journal-title":"Trends Pharmacol. Sci."},{"key":"D2TB00025C\/cit48\/1","doi-asserted-by":"crossref","first-page":"8780","DOI":"10.1021\/nn403202w","volume":"7","author":"Guo","year":"2013","journal-title":"ACS Nano"},{"key":"D2TB00025C\/cit49\/1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.biomaterials.2019.03.014","volume":"206","author":"Hu","year":"2019","journal-title":"Biomaterials"},{"key":"D2TB00025C\/cit50\/1","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1038\/emboj.2011.497","volume":"31","author":"Garg","year":"2012","journal-title":"EMBO J."},{"key":"D2TB00025C\/cit51\/1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.molmed.2012.06.010","volume":"18","author":"Garg","year":"2012","journal-title":"Trends Mol. Med."},{"key":"D2TB00025C\/cit52\/1","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/anie.201804882","volume":"58","author":"Duan","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2TB00025C\/cit53\/1","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1039\/D1TB00397F","volume":"9","author":"Yang","year":"2021","journal-title":"J. Mater. Chem. B"}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/TB\/D2TB00025C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:55:57Z","timestamp":1782849357000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/tb\/article\/10\/16\/3104-3118\/791553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":53,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2022,4,20]]}},"URL":"https:\/\/doi.org\/10.1039\/d2tb00025c","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}