{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T01:09:04Z","timestamp":1789520944771,"version":"build-2803163510"},"reference-count":33,"publisher":"Royal Society of Chemistry (RSC)","issue":"12","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"am","delay-in-days":416,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82003676"],"award-info":[{"award-number":["82003676"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>Immunotherapy based on host immunity has emerged as a powerful therapeutic strategy for tumor treatment.<\/jats:p>","DOI":"10.1039\/d2tb00197g","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T09:24:47Z","timestamp":1645435487000},"page":"2019-2027","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer"],"prefix":"10.1039","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9250-2782","authenticated-orcid":false,"given":"Xinlong","family":"Zang","sequence":"first","affiliation":[{"name":"School of Basic Medicine, Qingdao University, Ningxia Road 308, Qingdao, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxiao","family":"Song","sequence":"additional","affiliation":[{"name":"School of Basic Medicine, Qingdao University, Ningxia Road 308, Qingdao, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xie","family":"Yi","sequence":"additional","affiliation":[{"name":"School of Basic Medicine, Qingdao University, Ningxia Road 308, Qingdao, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Piyu","sequence":"additional","affiliation":[{"name":"Cangzhou Central Hospital, Xinhua West Road 16, Cangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2TB00197G\/cit1\/1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.jconrel.2020.04.040","volume":"323","author":"Liu","year":"2020","journal-title":"J. Controlled Release"},{"key":"D2TB00197G\/cit2\/1","doi-asserted-by":"crossref","first-page":"30297","DOI":"10.1021\/acsami.7b05654","volume":"9","author":"Wang","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00197G\/cit3\/1","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/anie.201804882","volume":"58","author":"Duan","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D2TB00197G\/cit4\/1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.jconrel.2021.05.034","volume":"335","author":"Xia","year":"2021","journal-title":"J. Controlled Release"},{"key":"D2TB00197G\/cit5\/1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.4161\/cbt.23624","volume":"14","author":"Zitron","year":"2013","journal-title":"Cancer Biol. Ther."},{"key":"D2TB00197G\/cit6\/1","doi-asserted-by":"crossref","first-page":"847","DOI":"10.3389\/fimmu.2018.00847","volume":"9","author":"Castro","year":"2018","journal-title":"Front. Immunol."},{"key":"D2TB00197G\/cit7\/1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.celrep.2015.08.077","volume":"13","author":"Holmgaard","year":"2015","journal-title":"Cell Rep."},{"key":"D2TB00197G\/cit8\/1","doi-asserted-by":"crossref","first-page":"4011","DOI":"10.1038\/s41467-020-17750-z","volume":"11","author":"Campesato","year":"2020","journal-title":"Nat. Commun."},{"key":"D2TB00197G\/cit9\/1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.3389\/fonc.2018.00370","volume":"8","author":"Fox","year":"2018","journal-title":"Front. Oncol."},{"key":"D2TB00197G\/cit10\/1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.jconrel.2020.02.043","volume":"321","author":"Liu","year":"2020","journal-title":"J. Controlled Release"},{"key":"D2TB00197G\/cit11\/1","doi-asserted-by":"crossref","first-page":"18033","DOI":"10.1021\/acsami.1c02567","volume":"13","author":"Deng","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00197G\/cit12\/1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jconrel.2017.05.006","volume":"258","author":"Sun","year":"2017","journal-title":"J. Controlled Release"},{"key":"D2TB00197G\/cit13\/1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.actbio.2020.11.008","volume":"119","author":"Zhu","year":"2021","journal-title":"Acta Biomater."},{"key":"D2TB00197G\/cit14\/1","doi-asserted-by":"crossref","first-page":"13443","DOI":"10.1038\/ncomms13443","volume":"7","author":"Chen","year":"2016","journal-title":"Nat. Commun."},{"key":"D2TB00197G\/cit15\/1","doi-asserted-by":"crossref","first-page":"120506","DOI":"10.1016\/j.ijpharm.2021.120506","volume":"601","author":"Li","year":"2021","journal-title":"Int. J. Pharm."},{"key":"D2TB00197G\/cit16\/1","doi-asserted-by":"crossref","first-page":"e1903277","DOI":"10.1002\/adma.201903277","volume":"31","author":"Zheng","year":"2019","journal-title":"Adv. Mater."},{"issue":"37","key":"D2TB00197G\/cit17\/1","doi-asserted-by":"crossref","first-page":"47946","DOI":"10.1002\/app.47946","volume":"136","author":"Ma","year":"2019","journal-title":"J. Appl. Polym. Sci."},{"key":"D2TB00197G\/cit18\/1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ajps.2018.11.005","volume":"15","author":"Qiu","year":"2020","journal-title":"Asian J. Pharm. Sci."},{"key":"D2TB00197G\/cit19\/1","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1007\/s00604-017-2255-7","volume":"184","author":"Hao","year":"2017","journal-title":"Microchim. Acta"},{"key":"D2TB00197G\/cit20\/1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.nano.2019.02.024","volume":"18","author":"Krishnamurthy","year":"2019","journal-title":"Nanomedicine"},{"key":"D2TB00197G\/cit21\/1","doi-asserted-by":"crossref","first-page":"120174","DOI":"10.1016\/j.ijpharm.2020.120174","volume":"594","author":"Zang","year":"2021","journal-title":"Int. J. Pharm."},{"key":"D2TB00197G\/cit22\/1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.actbio.2019.03.048","volume":"90","author":"Wan","year":"2019","journal-title":"Acta Biomater."},{"key":"D2TB00197G\/cit23\/1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.3389\/fbioe.2020.00769","volume":"8","author":"Gao","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"key":"D2TB00197G\/cit24\/1","doi-asserted-by":"crossref","first-page":"120388","DOI":"10.1016\/j.biomaterials.2020.120388","volume":"269","author":"Li","year":"2021","journal-title":"Biomaterials"},{"key":"D2TB00197G\/cit25\/1","doi-asserted-by":"crossref","first-page":"6246","DOI":"10.1021\/acs.nanolett.0c00713","volume":"20","author":"Dai","year":"2020","journal-title":"Nano Lett."},{"key":"D2TB00197G\/cit26\/1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.canlet.2019.11.009","volume":"470","author":"Lei","year":"2020","journal-title":"Cancer Lett."},{"key":"D2TB00197G\/cit27\/1","doi-asserted-by":"crossref","first-page":"583084","DOI":"10.3389\/fimmu.2020.583084","volume":"11","author":"Pan","year":"2020","journal-title":"Front. Immunol."},{"key":"D2TB00197G\/cit28\/1","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1021\/acs.molpharmaceut.9b00261","volume":"16","author":"Zang","year":"2019","journal-title":"Mol. Pharm."},{"key":"D2TB00197G\/cit29\/1","doi-asserted-by":"crossref","first-page":"128659","DOI":"10.1016\/j.cej.2021.128659","volume":"412","author":"Luo","year":"2021","journal-title":"Chem. Eng. J."},{"key":"D2TB00197G\/cit30\/1","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.3892\/ijo.2017.3975","volume":"50","author":"Pan","year":"2017","journal-title":"Int. J. Oncol."},{"key":"D2TB00197G\/cit31\/1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s13046-020-01709-5","volume":"39","author":"Jiang","year":"2020","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"D2TB00197G\/cit32\/1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/bs.ircmb.2017.07.004","volume":"336","author":"Prendergast","year":"2018","journal-title":"Int. Rev. Cell Mol. Biol."},{"key":"D2TB00197G\/cit33\/1","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1039\/C8BM00486B","volume":"6","author":"Sun","year":"2018","journal-title":"Biomater. Sci."}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/TB\/D2TB00197G","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:36:52Z","timestamp":1782927412000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/tb\/article\/10\/12\/2019-2027\/791603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,3,23]]}},"URL":"https:\/\/doi.org\/10.1039\/d2tb00197g","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}