{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:44:54Z","timestamp":1791870294592,"version":"4.3.4"},"reference-count":63,"publisher":"Royal Society of Chemistry (RSC)","issue":"34","license":[{"start":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000},"content-version":"am","delay-in-days":585,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81760087"],"award-info":[{"award-number":["81760087"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81560050"],"award-info":[{"award-number":["81560050"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008871","name":"Yunnan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2017FE467(-008)"],"award-info":[{"award-number":["2017FE467(-008)"]}],"id":[{"id":"10.13039\/501100008871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008871","name":"Yunnan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["202201AY070001-029"],"award-info":[{"award-number":["202201AY070001-029"]}],"id":[{"id":"10.13039\/501100008871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003996","name":"Kunming Medical University","doi-asserted-by":"publisher","award":["202201AY070001-029"],"award-info":[{"award-number":["202201AY070001-029"]}],"id":[{"id":"10.13039\/501100003996","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019413","name":"Yunnan Provincial Department of Education Science Research Fund Project","doi-asserted-by":"publisher","award":["2021J0228"],"award-info":[{"award-number":["2021J0228"]}],"id":[{"id":"10.13039\/501100019413","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017720","name":"Kunming Science and Technology Bureau","doi-asserted-by":"publisher","award":["2019-1-N-25318000003568"],"award-info":[{"award-number":["2019-1-N-25318000003568"]}],"id":[{"id":"10.13039\/100017720","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>Currently MI repair approaches always exhibit low efficiency and do not match the clinical requirements. To provide an advanced engineering platform, an injectable hydrogel was developed to release OSM continuously and localized in the MI lesion.<\/jats:p>","DOI":"10.1039\/d2tb00623e","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T23:01:48Z","timestamp":1659999708000},"page":"6514-6531","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Injectable hydrogel with dual-sensitive behavior for targeted delivery of oncostatin M to improve cardiac restoration after myocardial infarction"],"prefix":"10.1039","volume":"10","author":[{"given":"Yong-liang","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiwei","family":"Niu","sequence":"additional","affiliation":[{"name":"Yunnan Key Laboratory of Stem Cell and Regenerative Medicine, Science and Technology Achievement Incubation Center, Kunming Medical University, Kunming 650500, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limei","family":"Li","sequence":"additional","affiliation":[{"name":"Yunnan Key Laboratory of Stem Cell and Regenerative Medicine, Science and Technology Achievement Incubation Center, Kunming Medical University, Kunming 650500, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Yang","sequence":"additional","affiliation":[{"name":"Faculty of Basic Medical Science, Kunming Medical University, Kunming 650500, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Yunnan Key Laboratory of Innovative Application of Traditional Chinese Medicine, Department of Cardiovascular Surgery, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, Kunming 650100, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7675-4170","authenticated-orcid":false,"given":"Lin","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2022]]},"reference":[{"key":"D2TB00623E\/cit1\/1","doi-asserted-by":"crossref","first-page":"6401","DOI":"10.1039\/C5TB00739A","volume":"3","author":"Wu","year":"2015","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00623E\/cit2\/1","first-page":"e004402","volume":"10","author":"Khera","year":"2017","journal-title":"Circ.: Heart Failure"},{"key":"D2TB00623E\/cit3\/1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1146\/annurev-physiol-031120-103629","volume":"83","author":"Weinberger","year":"2021","journal-title":"Annu. Rev. Physiol."},{"issue":"5","key":"D2TB00623E\/cit4\/1","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1007\/s10753-021-01467-2","volume":"44","author":"Zhang","year":"2021","journal-title":"Inflammation"},{"key":"D2TB00623E\/cit5\/1","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1126\/science.1200708","volume":"331","author":"Porrello","year":"2011","journal-title":"Science"},{"key":"D2TB00623E\/cit6\/1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1161\/CIRCRESAHA.115.303567","volume":"115","author":"Heidt","year":"2014","journal-title":"Circ. Res."},{"key":"D2TB00623E\/cit7\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s00395-019-0742-1","volume":"114","author":"Podaru","year":"2019","journal-title":"Basic Res. Cardiol."},{"key":"D2TB00623E\/cit8\/1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12951-019-0504-0","volume":"17","author":"Beez","year":"2019","journal-title":"J. Nanobiotechnol."},{"key":"D2TB00623E\/cit9\/1","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1038\/s41467-019-10859-w","volume":"10","author":"Abe","year":"2019","journal-title":"Nat. Commun."},{"key":"D2TB00623E\/cit10\/1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.15252\/emmm.201606924","volume":"9","author":"Cambier","year":"2017","journal-title":"EMBO Mol. Med."},{"key":"D2TB00623E\/cit11\/1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/nm.3778","volume":"21","author":"Korf-Klingebiel","year":"2015","journal-title":"Nat. Med."},{"key":"D2TB00623E\/cit12\/1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.yjmcc.2013.11.015","volume":"70","author":"Shinde","year":"2014","journal-title":"J. Mol. Cell. Cardiol."},{"key":"D2TB00623E\/cit13\/1","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1039\/C8TB02591F","volume":"7","author":"Han","year":"2019","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00623E\/cit14\/1","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1161\/01.ATV.19.8.1835","volume":"19","author":"Vasse","year":"1999","journal-title":"Arterioscler., Thromb., Vasc. Biol."},{"key":"D2TB00623E\/cit15\/1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00395-010-0141-0","volume":"106","author":"Demyanets","year":"2011","journal-title":"Basic Res. Cardiol."},{"key":"D2TB00623E\/cit16\/1","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1039\/C9TB02523E","volume":"8","author":"Chen","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00623E\/cit17\/1","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1161\/CIRCULATIONAHA.119.044484","volume":"142","author":"Li","year":"2020","journal-title":"Circulation"},{"key":"D2TB00623E\/cit18\/1","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.stem.2011.08.013","volume":"9","author":"Kubin","year":"2011","journal-title":"Cell Stem Cell"},{"key":"D2TB00623E\/cit19\/1","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1096\/fj.08-108035","volume":"23","author":"Hohensinner","year":"2009","journal-title":"FASEB J."},{"key":"D2TB00623E\/cit20\/1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/nm.4307","volume":"23","author":"West","year":"2017","journal-title":"Nat. Med."},{"key":"D2TB00623E\/cit21\/1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.cytogfr.2015.07.006","volume":"26","author":"Hermanns","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"D2TB00623E\/cit22\/1","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1039\/D1TB01961A","volume":"10","author":"Fu","year":"2022","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00623E\/cit23\/1","doi-asserted-by":"crossref","first-page":"e2000454","DOI":"10.1002\/adhm.202000454","volume":"9","author":"Ding","year":"2020","journal-title":"Adv. Healthcare Mater."},{"key":"D2TB00623E\/cit24\/1","doi-asserted-by":"crossref","first-page":"38429","DOI":"10.1021\/acsami.9b12043","volume":"11","author":"Yuan","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00623E\/cit25\/1","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1080\/10717544.2018.1477863","volume":"25","author":"Niu","year":"2018","journal-title":"Drug Delivery"},{"key":"D2TB00623E\/cit26\/1","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.actbio.2021.03.024","volume":"126","author":"Niu","year":"2021","journal-title":"Acta Biomater."},{"key":"D2TB00623E\/cit27\/1","doi-asserted-by":"crossref","first-page":"136163","DOI":"10.1016\/j.cej.2022.136163","volume":"442","author":"Peng","year":"2022","journal-title":"Chem. Eng. J."},{"key":"D2TB00623E\/cit28\/1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.actbio.2020.10.045","volume":"119","author":"Domenge","year":"2021","journal-title":"Acta Biomater."},{"key":"D2TB00623E\/cit29\/1","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s10439-020-02471-7","volume":"48","author":"Ding","year":"2020","journal-title":"Ann. Biomed. Eng."},{"key":"D2TB00623E\/cit30\/1","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1016\/j.biomaterials.2010.11.075","volume":"32","author":"Garbern","year":"2011","journal-title":"Biomaterials"},{"key":"D2TB00623E\/cit31\/1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biomaterials.2018.05.003","volume":"178","author":"Ma","year":"2018","journal-title":"Biomaterials"},{"key":"D2TB00623E\/cit32\/1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12951-019-0529-4","volume":"17","author":"Niu","year":"2019","journal-title":"J. Nanobiotechnol."},{"key":"D2TB00623E\/cit33\/1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.ijbiomac.2008.07.019","volume":"43","author":"Tang","year":"2008","journal-title":"Int. J. Biol. Macromol."},{"key":"D2TB00623E\/cit34\/1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12951-019-0451-9","volume":"17","author":"Zhang","year":"2019","journal-title":"J. Nanobiotechnol."},{"key":"D2TB00623E\/cit35\/1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ijbiomac.2012.12.048","volume":"55","author":"Li","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"D2TB00623E\/cit36\/1","doi-asserted-by":"crossref","first-page":"10398","DOI":"10.1021\/acsami.6b14676","volume":"9","author":"Pitakchatwong","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D2TB00623E\/cit37\/1","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1021\/bm5010004","volume":"15","author":"Yang","year":"2014","journal-title":"Biomacromolecules"},{"key":"D2TB00623E\/cit38\/1","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/j.carbpol.2012.07.007","volume":"90","author":"D'Este","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"D2TB00623E\/cit39\/1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.actbio.2022.01.043","volume":"141","author":"Ross","year":"2022","journal-title":"Acta Biomater."},{"key":"D2TB00623E\/cit40\/1","doi-asserted-by":"crossref","first-page":"119643","DOI":"10.1016\/j.carbpol.2022.119643","volume":"292","author":"Wang","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"D2TB00623E\/cit41\/1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1021\/mz200121k","volume":"1","author":"Patenaude","year":"2012","journal-title":"ACS Macro Lett."},{"key":"D2TB00623E\/cit42\/1","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1016\/j.biomaterials.2011.11.085","volume":"33","author":"Lai","year":"2012","journal-title":"Biomaterials"},{"key":"D2TB00623E\/cit43\/1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ejpb.2016.11.038","volume":"113","author":"Lai","year":"2017","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D2TB00623E\/cit44\/1","doi-asserted-by":"crossref","first-page":"117812","DOI":"10.1016\/j.carbpol.2021.117812","volume":"260","author":"Hoang","year":"2021","journal-title":"Carbohydr.\nPolym."},{"key":"D2TB00623E\/cit45\/1","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1111\/jcmm.12501","volume":"19","author":"Sun","year":"2015","journal-title":"J. Cell. Mol. Med."},{"key":"D2TB00623E\/cit46\/1","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1113\/EP088584","volume":"105","author":"Wang","year":"2020","journal-title":"Exp. Physiol."},{"key":"D2TB00623E\/cit47\/1","first-page":"E11741","volume":"115","author":"Ma","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D2TB00623E\/cit48\/1","doi-asserted-by":"crossref","first-page":"H183","DOI":"10.1152\/ajpheart.00229.2016","volume":"311","author":"Fan","year":"2016","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"D2TB00623E\/cit49\/1","doi-asserted-by":"crossref","first-page":"20666","DOI":"10.1074\/jbc.M512671200","volume":"281","author":"Kenessey","year":"2006","journal-title":"J. Biol. Chem."},{"key":"D2TB00623E\/cit50\/1","doi-asserted-by":"crossref","first-page":"H24","DOI":"10.1152\/ajpheart.00521.2018","volume":"316","author":"Wodsedalek","year":"2019","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"D2TB00623E\/cit51\/1","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.celrep.2019.06.065","volume":"28","author":"Yue","year":"2019","journal-title":"Cell Rep."},{"key":"D2TB00623E\/cit52\/1","doi-asserted-by":"crossref","first-page":"10892","DOI":"10.7150\/thno.47913","volume":"10","author":"Wang","year":"2020","journal-title":"Theranostics"},{"key":"D2TB00623E\/cit53\/1","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1111\/j.1538-7836.2010.03741.x","volume":"8","author":"Rychli","year":"2010","journal-title":"J. Thromb. Haemostasis"},{"key":"D2TB00623E\/cit54\/1","first-page":"317905","volume":"2015","author":"Zhang","year":"2015","journal-title":"BioMed Res. Int."},{"key":"D2TB00623E\/cit55\/1","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/j.bbadis.2016.11.004","volume":"1863","author":"Hu","year":"2017","journal-title":"Biochim. Biophys. Acta, Mol. Basis Dis."},{"key":"D2TB00623E\/cit56\/1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nm.3816","volume":"21","author":"Lorchner","year":"2015","journal-title":"Nat. Med."},{"key":"D2TB00623E\/cit57\/1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1161\/CIRCRESAHA.116.303577","volume":"119","author":"Prabhu","year":"2016","journal-title":"Circ. Res."},{"key":"D2TB00623E\/cit58\/1","doi-asserted-by":"crossref","first-page":"7713","DOI":"10.1039\/D0TB01320J","volume":"8","author":"Gao","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"D2TB00623E\/cit59\/1","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1007\/s10495-015-1148-7","volume":"20","author":"Zhang","year":"2015","journal-title":"Apoptosis"},{"key":"D2TB00623E\/cit60\/1","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1073\/pnas.1015623108","volume":"108","author":"Harel-Adar","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D2TB00623E\/cit61\/1","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1172\/JCI85782","volume":"126","author":"Shiraishi","year":"2016","journal-title":"J. Clin. Invest."},{"key":"D2TB00623E\/cit62\/1","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1161\/CIRCULATIONAHA.116.023106","volume":"135","author":"Choo","year":"2017","journal-title":"Circulation"},{"key":"D2TB00623E\/cit63\/1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nrd.2017.106","volume":"16","author":"Cahill","year":"2017","journal-title":"Nat. Rev. Drug Discovery"}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2022\/TB\/D2TB00623E","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:07:38Z","timestamp":1782929258000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/tb\/article\/10\/34\/6514-6531\/791742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":63,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2022,8,31]]}},"URL":"https:\/\/doi.org\/10.1039\/d2tb00623e","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}