{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:13:41Z","timestamp":1791630821140,"version":"4.3.4"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"24","license":[{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"am","delay-in-days":416,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["UMO-2018\/30\/E\/ST5\/00576"],"award-info":[{"award-number":["UMO-2018\/30\/E\/ST5\/00576"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>We have shown that clotrimazole formulations encapsulated in polyether-based unimolecular micelles have significantly higher antitumour activity than the drug itself.<\/jats:p>","DOI":"10.1039\/d2tb02629e","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T08:45:28Z","timestamp":1676969128000},"page":"5552-5564","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Cross-linkable star-hyperbranched unimolecular micelles for the enhancement of the anticancer activity of clotrimazole"],"prefix":"10.1039","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4901-4687","authenticated-orcid":false,"given":"Mateusz","family":"Gosecki","sequence":"first","affiliation":[{"name":"Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0669-3373","authenticated-orcid":false,"given":"Piotr","family":"Ziemczonek","sequence":"additional","affiliation":[{"name":"Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4358-0987","authenticated-orcid":false,"given":"Monika","family":"Gosecka","sequence":"additional","affiliation":[{"name":"Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9100-0924","authenticated-orcid":false,"given":"Malgorzata","family":"Urbaniak","sequence":"additional","affiliation":[{"name":"Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewelina","family":"Wielgus","sequence":"additional","affiliation":[{"name":"Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Marcinkowska","sequence":"additional","affiliation":[{"name":"Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141\/143 Pomorska Street, 90-236 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8872-8092","authenticated-orcid":false,"given":"Anna","family":"Janaszewska","sequence":"additional","affiliation":[{"name":"Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141\/143 Pomorska Street, 90-236 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3459-8947","authenticated-orcid":false,"given":"Barbara","family":"Klajnert-Maculewicz","sequence":"additional","affiliation":[{"name":"Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141\/143 Pomorska Street, 90-236 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D2TB02629E\/cit1\/1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3389\/fphar.2014.00077","volume":"5","author":"Jhaveri","year":"2014","journal-title":"Front. Pharmacol."},{"key":"D2TB02629E\/cit2\/1","doi-asserted-by":"crossref","first-page":"4985","DOI":"10.1007\/s12274-018-2152-3","volume":"11","author":"Lu","year":"2018","journal-title":"Nano Res."},{"key":"D2TB02629E\/cit3\/1","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1021\/bm200372s","volume":"12","author":"Li","year":"2011","journal-title":"Biomacromolecules"},{"key":"D2TB02629E\/cit4\/1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.addr.2014.10.001","volume":"91","author":"Eetezadi","year":"2015","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2TB02629E\/cit5\/1","doi-asserted-by":"crossref","first-page":"6179","DOI":"10.1021\/acsnano.8b02830","volume":"12","author":"Sun","year":"2018","journal-title":"ACS Nano"},{"key":"D2TB02629E\/cit6\/1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jconrel.2014.12.012","volume":"199","author":"Xu","year":"2015","journal-title":"J. Controlled Release"},{"key":"D2TB02629E\/cit7\/1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jconrel.2015.08.054","volume":"219","author":"Wang","year":"2015","journal-title":"J. Controlled Release"},{"key":"D2TB02629E\/cit8\/1","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1021\/mp050020d","volume":"2","author":"Ambade","year":"2005","journal-title":"Mol. Pharmaceutics"},{"key":"D2TB02629E\/cit9\/1","doi-asserted-by":"crossref","first-page":"5898","DOI":"10.1039\/C6PY01006G","volume":"7","author":"Fan","year":"2016","journal-title":"Polym. Chem."},{"key":"D2TB02629E\/cit10\/1","doi-asserted-by":"crossref","first-page":"122716","DOI":"10.1016\/j.polymer.2020.122716","volume":"202","author":"Liang","year":"2020","journal-title":"Polymer"},{"key":"D2TB02629E\/cit11\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/pj.2010.93","volume":"43","author":"Luo","year":"2011","journal-title":"Polym. J."},{"key":"D2TB02629E\/cit12\/1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jcis.2014.03.034","volume":"425","author":"Rezaei","year":"2014","journal-title":"J. Colloid Interface Sci."},{"key":"D2TB02629E\/cit13\/1","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1016\/j.polymer.2012.05.056","volume":"53","author":"Rezaei","year":"2012","journal-title":"Polymer"},{"key":"D2TB02629E\/cit14\/1","doi-asserted-by":"crossref","first-page":"8386","DOI":"10.3390\/ijms22168386","volume":"22","author":"Ziemczonek","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D2TB02629E\/cit15\/1","doi-asserted-by":"crossref","first-page":"4203","DOI":"10.1021\/acs.biomac.2c00691","volume":"23","author":"Gosecka","year":"2022","journal-title":"Biomacromolecules"},{"key":"D2TB02629E\/cit16\/1","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.3390\/ma12203323","volume":"12","author":"Mantha","year":"2019","journal-title":"Materials"},{"key":"D2TB02629E\/cit17\/1","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1021\/cr000108x","volume":"101","author":"Lee","year":"2001","journal-title":"Chem. Rev."},{"key":"D2TB02629E\/cit18\/1","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1016\/S0142-9612(03)00340-5","volume":"24","author":"Drury","year":"2003","journal-title":"Biomaterials"},{"key":"D2TB02629E\/cit19\/1","doi-asserted-by":"crossref","first-page":"8280","DOI":"10.1073\/pnas.95.14.8280","volume":"95","author":"Aktas","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D2TB02629E\/cit20\/1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1128\/AAC.2.6.423","volume":"2","author":"Burgess","year":"1972","journal-title":"Antimicrob. Agents Chemother."},{"key":"D2TB02629E\/cit21\/1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.molliq.2018.02.068","volume":"256","author":"Saadatfar","year":"2018","journal-title":"J. Mol. Liq."},{"key":"D2TB02629E\/cit22\/1","doi-asserted-by":"crossref","first-page":"47769","DOI":"10.1002\/app.47769","volume":"136","author":"Kareem","year":"2019","journal-title":"J. Appl. Polym. Sci."},{"key":"D2TB02629E\/cit23\/1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1096-7192(02)00046-X","volume":"76","author":"Penso","year":"2002","journal-title":"Mol. Genet. Metab."},{"key":"D2TB02629E\/cit24\/1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0014-2999(02)02103-9","volume":"451","author":"Penso","year":"2002","journal-title":"Eur. J. Pharmacol."},{"key":"D2TB02629E\/cit25\/1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/1523-1747.ep12470043","volume":"100","author":"Hegemann","year":"1993","journal-title":"J. Invest. Dermatol."},{"key":"D2TB02629E\/cit26\/1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ymgme.2005.11.002","volume":"87","author":"Marinho-Carvalho","year":"2006","journal-title":"Mol. Genet. Metab."},{"key":"D2TB02629E\/cit27\/1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.4161\/mabs.29089","volume":"6","author":"Fauvel","year":"2014","journal-title":"MAbs"},{"key":"D2TB02629E\/cit28\/1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/nrc3579","volume":"13","author":"Parks","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"D2TB02629E\/cit29\/1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1126\/science.123.3191.309","volume":"123","author":"Warburg","year":"1956","journal-title":"Science"},{"key":"D2TB02629E\/cit30\/1","doi-asserted-by":"crossref","first-page":"e30462","DOI":"10.1371\/journal.pone.0030462","volume":"7","author":"Furtado","year":"2012","journal-title":"PLoS One"},{"key":"D2TB02629E\/cit31\/1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF02977701","volume":"30","author":"Prabagar","year":"2007","journal-title":"Arch. Pharmacal Res."},{"key":"D2TB02629E\/cit32\/1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.rpor.2018.09.002","volume":"23","author":"Porras","year":"2018","journal-title":"Rep. Pract. Oncol. Radiother."},{"key":"D2TB02629E\/cit33\/1","doi-asserted-by":"crossref","first-page":"5898","DOI":"10.1039\/C6PY01006G","volume":"7","author":"Fan","year":"2016","journal-title":"Polym. Chem."},{"key":"D2TB02629E\/cit34\/1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.addr.2018.07.008","volume":"130","author":"Chen","year":"2018","journal-title":"Adv. Drug Delivery Rev."},{"key":"D2TB02629E\/cit35\/1","doi-asserted-by":"crossref","first-page":"3951","DOI":"10.1039\/D0PY00393J","volume":"11","author":"Celentano","year":"2020","journal-title":"Polym. Chem."},{"key":"D2TB02629E\/cit36\/1","doi-asserted-by":"crossref","first-page":"18323","DOI":"10.1021\/acs.jpcc.6b06365","volume":"120","author":"Gosecki","year":"2016","journal-title":"J. Phys. Chem. C"},{"key":"D2TB02629E\/cit37\/1","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1021\/acs.biomac.7b01071","volume":"18","author":"Gosecki","year":"2017","journal-title":"Biomacromolecules"},{"key":"D2TB02629E\/cit38\/1","doi-asserted-by":"crossref","first-page":"118959","DOI":"10.1016\/j.ijpharm.2019.118959","volume":"576","author":"Jafari","year":"2020","journal-title":"Int. J. Pharm."},{"key":"D2TB02629E\/cit39\/1","doi-asserted-by":"crossref","first-page":"42951","DOI":"10.1002\/app.42951","volume":"133","author":"Ying","year":"2016","journal-title":"J. Appl. Polym. Sci."},{"key":"D2TB02629E\/cit40\/1","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1021\/bm500705x","volume":"15","author":"Wu","year":"2014","journal-title":"Biomacromolecules"},{"key":"D2TB02629E\/cit41\/1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.colsurfb.2012.10.026","volume":"103","author":"Postnova","year":"2013","journal-title":"Colloids Surf., B"},{"key":"D2TB02629E\/cit42\/1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/jbm.a.35539","volume":"104","author":"Haryanto","year":"2016","journal-title":"J. Biomed. Mater. Res., Part A"},{"key":"D2TB02629E\/cit43\/1","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1002\/pola.26496","volume":"51","author":"Schomer","year":"2013","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"D2TB02629E\/cit44\/1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1021\/ar900158p","volume":"43","author":"Wilms","year":"2010","journal-title":"Acc. Chem. Res."},{"key":"D2TB02629E\/cit45\/1","doi-asserted-by":"crossref","first-page":"4240","DOI":"10.1021\/ma990090w","volume":"32","author":"Sunder","year":"1999","journal-title":"Macromolecules"},{"key":"D2TB02629E\/cit46\/1","volume-title":"Drug delivery systems: Advanced technologies potentially applicable in personalized treatments","author":"dos Santos","year":"2013","unstructured":"B. M. S.dos Santos ,  T.dos Santos  and  F. E.Antunes ,  Drug delivery systems: Advanced technologies potentially applicable in personalized treatments ,  Springer ,  2013"},{"key":"D2TB02629E\/cit47\/1","doi-asserted-by":"crossref","first-page":"e98885","DOI":"10.1371\/journal.pone.0098885","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"D2TB02629E\/cit48\/1","doi-asserted-by":"crossref","first-page":"918","DOI":"10.3171\/jns.1999.90.5.0918","volume":"90","author":"Khalid","year":"1999","journal-title":"J. Neurosurg."},{"key":"D2TB02629E\/cit49\/1","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1124\/jpet.103.059618","volume":"308","author":"Cao","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"D2TB02629E\/cit50\/1","volume-title":"Purification of laboratory chemicals","author":"Armarego","year":"2013","unstructured":"W. L. F.Armarego  and  C. L. L.Chai ,  Purification of laboratory chemicals ,  Elsevier\/Butterworth-Heinemann ,  Amsterdam London , 7th edn,  2013"},{"key":"D2TB02629E\/cit51\/1","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1055\/s-1987-28203","author":"Fitton","year":"1987","journal-title":"Synthesis"},{"key":"D2TB02629E\/cit52\/1","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1021\/ma702458g","volume":"41","author":"Wurm","year":"2008","journal-title":"Macromolecules"}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/TB\/D2TB02629E","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:18:14Z","timestamp":1782883094000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/tb\/article\/11\/24\/5552-5564\/792306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":52,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2023,6,21]]}},"URL":"https:\/\/doi.org\/10.1039\/d2tb02629e","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}