{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:04:40Z","timestamp":1787004280220,"version":"build-2736575974"},"reference-count":32,"publisher":"Royal Society of Chemistry (RSC)","issue":"5","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"am","delay-in-days":389,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82304453"],"award-info":[{"award-number":["82304453"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>In this study, a novel method capable of measuring enzyme activity of insoluble substrates was designed based on ordered porous layer interferometry (OPLI) technique, which shows advantages in the evaluation of thrombolytic drugs.<\/jats:p>","DOI":"10.1039\/d3an02054a","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T22:02:07Z","timestamp":1706047327000},"page":"1537-1547","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Measurement of enzyme activity of insoluble substrates based on ordered porous layer interferometry and the application in evaluation of thrombolytic drugs"],"prefix":"10.1039","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5160-3756","authenticated-orcid":false,"given":"Qianqian","family":"Su","sequence":"first","affiliation":[{"name":"Pharmacy School, Jiangsu Ocean University, Lianyungang 222005, China"},{"name":"Jiangsu Key Laboratory of Marine Drug Screening, Lianyungang 222005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Sun","sequence":"additional","affiliation":[{"name":"Pharmacy School, Jiangsu Ocean University, Lianyungang 222005, China"},{"name":"Jiangsu Key Laboratory of Marine Drug Screening, Lianyungang 222005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhua","family":"Tang","sequence":"additional","affiliation":[{"name":"Pharmacy School, Jiangsu Ocean University, Lianyungang 222005, China"},{"name":"Jiangsu Key Laboratory of Marine Drug Screening, Lianyungang 222005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Ni","sequence":"additional","affiliation":[{"name":"Pharmacy School, Jiangsu Ocean University, Lianyungang 222005, China"},{"name":"Jiangsu Key Laboratory of Marine Drug Screening, Lianyungang 222005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nian","family":"Ding","sequence":"additional","affiliation":[{"name":"Pharmacy School, Jiangsu Ocean University, Lianyungang 222005, China"},{"name":"Jiangsu Key Laboratory of Marine Drug Screening, Lianyungang 222005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3AN02054A\/cit1\/1","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1039\/C8AN02072H","volume":"144","author":"Yu","year":"2019","journal-title":"Analyst"},{"key":"D3AN02054A\/cit2\/1","doi-asserted-by":"crossref","first-page":"e15878","DOI":"10.1097\/MD.0000000000015878","volume":"98","author":"Aldossari","year":"2019","journal-title":"Medicine"},{"key":"D3AN02054A\/cit3\/1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/978-1-4939-9236-2_22","volume":"1978","author":"Janssen","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"D3AN02054A\/cit4\/1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jbiosc.2016.12.002","volume":"123","author":"Park","year":"2017","journal-title":"J. Biosci. Bioeng."},{"key":"D3AN02054A\/cit5\/1","doi-asserted-by":"crossref","first-page":"S133","DOI":"10.33549\/physiolres.932621","volume":"63","author":"Pavelka","year":"2014","journal-title":"Physiol. Res."},{"key":"D3AN02054A\/cit6\/1","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1177\/1087057109336592","volume":"14","author":"Sukumaran","year":"2009","journal-title":"J. Biomol. Screening"},{"key":"D3AN02054A\/cit7\/1","doi-asserted-by":"crossref","first-page":"124329","DOI":"10.1016\/j.talanta.2023.124329","volume":"257","author":"Wang","year":"2023","journal-title":"Talanta"},{"key":"D3AN02054A\/cit8\/1","doi-asserted-by":"crossref","first-page":"6337","DOI":"10.2147\/IJN.S167380","volume":"13","author":"Zhang","year":"2018","journal-title":"Int. J. Nanomed."},{"key":"D3AN02054A\/cit9\/1","first-page":"395","volume":"109","author":"Gauglitz","year":"2008","journal-title":"Adv. Biochem. Eng.\/Biotechnol."},{"key":"D3AN02054A\/cit10\/1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/978-1-4939-6848-0_13","volume":"1571","author":"Proll","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"D3AN02054A\/cit11\/1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00216-004-2895-4","volume":"381","author":"Gauglitz","year":"2005","journal-title":"Anal. Bioanal. Chem."},{"key":"D3AN02054A\/cit12\/1","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1007\/s00216-010-3904-4","volume":"398","author":"Gauglitz","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"D3AN02054A\/cit13\/1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/jmr.862","volume":"20","author":"Rich","year":"2007","journal-title":"J. Mol. Recognit."},{"key":"D3AN02054A\/cit14\/1","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1126\/science.278.5339.840","volume":"278","author":"Lin","year":"1997","journal-title":"Science"},{"key":"D3AN02054A\/cit15\/1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.3390\/bios13070730","volume":"13","author":"Wan","year":"2023","journal-title":"Biosensors"},{"key":"D3AN02054A\/cit16\/1","doi-asserted-by":"crossref","first-page":"15809","DOI":"10.1021\/acs.analchem.2c03582","volume":"94","author":"Zhou","year":"2022","journal-title":"Anal. Chem."},{"key":"D3AN02054A\/cit17\/1","doi-asserted-by":"crossref","first-page":"122958","DOI":"10.1016\/j.talanta.2021.122958","volume":"237","author":"Wang","year":"2022","journal-title":"Talanta"},{"key":"D3AN02054A\/cit18\/1","doi-asserted-by":"crossref","first-page":"340582","DOI":"10.1016\/j.aca.2022.340582","volume":"1236","author":"Yan","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"D3AN02054A\/cit19\/1","doi-asserted-by":"crossref","first-page":"130553","DOI":"10.1016\/j.foodchem.2021.130553","volume":"366","author":"Zhou","year":"2022","journal-title":"Food Chem."},{"key":"D3AN02054A\/cit20\/1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0956-5663(94)80105-3","volume":"9","author":"Striebel","year":"1994","journal-title":"Biosens. Bioelectron."},{"key":"D3AN02054A\/cit21\/1","doi-asserted-by":"crossref","first-page":"15565","DOI":"10.1021\/acsami.2c02113","volume":"14","author":"Guo","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D3AN02054A\/cit22\/1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jconrel.2009.05.035","volume":"140","author":"Simberg","year":"2009","journal-title":"J. Controlled Release"},{"key":"D3AN02054A\/cit23\/1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nnano.2009.11","volume":"4","author":"Orosco","year":"2009","journal-title":"Nat. Nanotechnol."},{"key":"D3AN02054A\/cit24\/1","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1021\/acs.molpharmaceut.0c00960","volume":"18","author":"Bezem","year":"2021","journal-title":"Mol. Pharm."},{"key":"D3AN02054A\/cit25\/1","doi-asserted-by":"crossref","first-page":"315709","DOI":"10.1088\/0957-4484\/19\/31\/315709","volume":"19","author":"Casanova","year":"2008","journal-title":"Nanotechnology"},{"key":"D3AN02054A\/cit26\/1","doi-asserted-by":"crossref","first-page":"11878","DOI":"10.3390\/s140711878","volume":"14","author":"Kumeria","year":"2014","journal-title":"Sensors"},{"key":"D3AN02054A\/cit27\/1","doi-asserted-by":"crossref","first-page":"35950","DOI":"10.1021\/acsami.0c10926","volume":"12","author":"Su","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D3AN02054A\/cit28\/1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.2174\/157016311796799026","volume":"8","author":"Simovic","year":"2011","journal-title":"Curr. Drug Discovery Technol."},{"key":"D3AN02054A\/cit29\/1","doi-asserted-by":"crossref","first-page":"123872","DOI":"10.1016\/j.ijbiomac.2023.123872","volume":"235","author":"Wang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"D3AN02054A\/cit30\/1","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.ijbiomac.2022.01.185","volume":"203","author":"Ma","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"D3AN02054A\/cit31\/1","doi-asserted-by":"crossref","first-page":"8367","DOI":"10.1166\/jnn.2018.16415","volume":"18","author":"Su","year":"2018","journal-title":"J. Nanosci. Nanotechnol."},{"key":"D3AN02054A\/cit32\/1","doi-asserted-by":"crossref","first-page":"6080","DOI":"10.1021\/acs.analchem.9b00620","volume":"91","author":"Su","year":"2019","journal-title":"Anal. Chem."}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/AN\/D3AN02054A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:33:16Z","timestamp":1783449196000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/149\/5\/1537-1547\/795247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,2,26]]}},"URL":"https:\/\/doi.org\/10.1039\/d3an02054a","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}