{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:32:08Z","timestamp":1782894728785,"version":"3.54.5"},"reference-count":39,"publisher":"Royal Society of Chemistry (RSC)","issue":"9","license":[{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"am","delay-in-days":430,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270092"],"award-info":[{"award-number":["82270092"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32071379"],"award-info":[{"award-number":["32071379"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing","doi-asserted-by":"publisher","award":["CSTB2023NSCQ-ZDJ0017"],"award-info":[{"award-number":["CSTB2023NSCQ-ZDJ0017"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing","doi-asserted-by":"publisher","award":["cstc2021ycjh-bgzxm0011"],"award-info":[{"award-number":["cstc2021ycjh-bgzxm0011"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012397","name":"Army Medical University","doi-asserted-by":"publisher","award":["2022YQB024"],"award-info":[{"award-number":["2022YQB024"]}],"id":[{"id":"10.13039\/501100012397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>A magnesium-free assembly method that utilizes tobramycin as a mediator to assemble DNA nanostructures is proposed. Targeting of PA is achieved by incorporating maleimide-modified DNA into the nanostructures, directed towards the pili of PA.<\/jats:p>","DOI":"10.1039\/d3bm02121a","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T02:31:42Z","timestamp":1709692302000},"page":"2331-2340","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Tobramycin-mediated self-assembly of DNA nanostructures for targeted treatment of\n                    <i>Pseudomonas aeruginosa<\/i>\n                    -infected lung inflammation"],"prefix":"10.1039","volume":"12","author":[{"given":"Yuhang","family":"Xu","sequence":"first","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-8444","authenticated-orcid":false,"given":"Qian","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"},{"name":"Laboratory of Pharmacy and Chemistry, and Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, 400016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daohui","family":"Gong","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9311-0799","authenticated-orcid":false,"given":"Chuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guansong","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9548-8894","authenticated-orcid":false,"given":"Hang","family":"Qian","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Chongqing 400037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3BM02121A\/cit1\/1","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1016\/S0140-6736(16)00576-6","volume":"388","author":"Elborn","year":"2016","journal-title":"Lancet"},{"key":"D3BM02121A\/cit2\/1","doi-asserted-by":"crossref","first-page":"eaav4634","DOI":"10.1126\/scitranslmed.aav4634","volume":"11","author":"Riquelme","year":"2019","journal-title":"Sci. Transl. Med."},{"key":"D3BM02121A\/cit3\/1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.addr.2014.11.017","volume":"85","author":"Ciofu","year":"2015","journal-title":"Adv. Drug Delivery Rev."},{"key":"D3BM02121A\/cit4\/1","doi-asserted-by":"crossref","first-page":"8671","DOI":"10.3390\/ijms21228671","volume":"21","author":"Thi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D3BM02121A\/cit5\/1","first-page":"CD002009","volume":"9","author":"Bhatt","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"D3BM02121A\/cit6\/1","doi-asserted-by":"crossref","first-page":"5132","DOI":"10.1038\/s41467-023-40830-9","volume":"14","author":"Liu","year":"2023","journal-title":"Nat. Commun."},{"key":"D3BM02121A\/cit7\/1","doi-asserted-by":"crossref","first-page":"e2006772","DOI":"10.1002\/adma.202006772","volume":"33","author":"Ye","year":"2021","journal-title":"Adv. Mater."},{"key":"D3BM02121A\/cit8\/1","doi-asserted-by":"crossref","first-page":"e2109789","DOI":"10.1002\/adma.202109789","volume":"34","author":"Feng","year":"2022","journal-title":"Adv. Mater."},{"key":"D3BM02121A\/cit9\/1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1126\/science.aan5706","volume":"358","author":"Ellison","year":"2017","journal-title":"Science"},{"key":"D3BM02121A\/cit10\/1","doi-asserted-by":"crossref","first-page":"120588","DOI":"10.1016\/j.biomaterials.2020.120588","volume":"268","author":"Wu","year":"2021","journal-title":"Biomaterials"},{"key":"D3BM02121A\/cit11\/1","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1038\/s41596-019-0162-6","volume":"14","author":"Ellison","year":"2019","journal-title":"Nat. Protoc."},{"key":"D3BM02121A\/cit12\/1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1039\/C7CS00748E","volume":"48","author":"Gupta","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"D3BM02121A\/cit13\/1","doi-asserted-by":"crossref","first-page":"eade8039","DOI":"10.1126\/sciadv.ade8039","volume":"9","author":"Finbloom","year":"2023","journal-title":"Sci. Adv."},{"key":"D3BM02121A\/cit14\/1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1039\/C7CS00748E","volume":"48","author":"Gupta","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"D3BM02121A\/cit15\/1","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.2147\/IJN.S218966","volume":"15","author":"Falciani","year":"2020","journal-title":"Int. J. Nanomed."},{"key":"D3BM02121A\/cit16\/1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.cell.2018.06.026","volume":"12","author":"Zhou","year":"2018","journal-title":"Cell"},{"key":"D3BM02121A\/cit17\/1","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1021\/acsami.7b17928","volume":"10","author":"Zhang","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D3BM02121A\/cit18\/1","doi-asserted-by":"crossref","first-page":"15442","DOI":"10.1021\/acsami.8b02626","volume":"10","author":"Xia","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D3BM02121A\/cit19\/1","doi-asserted-by":"crossref","first-page":"12733","DOI":"10.1021\/acsami.6b03786","volume":"8","author":"Peng","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D3BM02121A\/cit20\/1","doi-asserted-by":"crossref","first-page":"12698","DOI":"10.1002\/anie.202002740","volume":"59","author":"Mela","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3BM02121A\/cit21\/1","doi-asserted-by":"crossref","first-page":"5652","DOI":"10.1021\/acs.nanolett.8b02166","volume":"8","author":"Zhang","year":"2018","journal-title":"Nano Lett."},{"key":"D3BM02121A\/cit22\/1","doi-asserted-by":"crossref","first-page":"e1800185","DOI":"10.1002\/smll.201800185","volume":"14","author":"Yang","year":"2018","journal-title":"Small"},{"key":"D3BM02121A\/cit23\/1","doi-asserted-by":"crossref","first-page":"6459","DOI":"10.1021\/acs.chemrev.7b00663","volume":"119","author":"Hu","year":"2019","journal-title":"Chem. Rev."},{"key":"D3BM02121A\/cit24\/1","doi-asserted-by":"crossref","first-page":"15818","DOI":"10.1002\/anie.201916390","volume":"59","author":"Keller","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3BM02121A\/cit25\/1","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1002\/asia.201900574","volume":"14","author":"Lu","year":"2019","journal-title":"Chem. \u2013 Asian J."},{"key":"D3BM02121A\/cit26\/1","first-page":"2946","volume":"6","author":"Wang","year":"2021","journal-title":"Bioact. Mater."},{"key":"D3BM02121A\/cit27\/1","doi-asserted-by":"crossref","first-page":"e1906975","DOI":"10.1002\/smll.201906975","volume":"16","author":"Wu","year":"2020","journal-title":"Small"},{"key":"D3BM02121A\/cit28\/1","doi-asserted-by":"crossref","first-page":"15504","DOI":"10.1021\/acsami.8b03464","volume":"10","author":"Wang","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D3BM02121A\/cit29\/1","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1038\/s41596-021-00515-3","volume":"16","author":"Haney","year":"2021","journal-title":"Nat. Protoc."},{"key":"D3BM02121A\/cit30\/1","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1002\/smll.201301891","volume":"10","author":"Qian","year":"2014","journal-title":"Small"},{"key":"D3BM02121A\/cit31\/1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.biomaterials.2015.07.015","volume":"67","author":"You","year":"2015","journal-title":"Biomaterials"},{"key":"D3BM02121A\/cit32\/1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1146\/annurev-micro-092611-150055","volume":"66","author":"Burrows","year":"2012","journal-title":"Annu. Rev. Microbiol."},{"key":"D3BM02121A\/cit33\/1","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3389\/fmicb.2015.00190","volume":"6","author":"Pohlschroder","year":"2015","journal-title":"Front. Microbiol."},{"key":"D3BM02121A\/cit34\/1","doi-asserted-by":"crossref","first-page":"e2101759118","DOI":"10.1073\/pnas.2101759118","volume":"118","author":"K\u00fchn","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3BM02121A\/cit35\/1","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.tim.2015.09.002","volume":"23","author":"Maier","year":"2015","journal-title":"Trends Microbiol."},{"key":"D3BM02121A\/cit36\/1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/femsre\/fuu001","volume":"39","author":"Berry","year":"2015","journal-title":"FEMS Microbiol. Rev."},{"key":"D3BM02121A\/cit37\/1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1126\/science.1194238","volume":"330","author":"Gibiansky","year":"2010","journal-title":"Science"},{"key":"D3BM02121A\/cit38\/1","doi-asserted-by":"crossref","first-page":"2111066","DOI":"10.1002\/adfm.202111066","volume":"32","author":"Zhu","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"D3BM02121A\/cit39\/1","doi-asserted-by":"crossref","first-page":"101892","DOI":"10.1016\/j.nantod.2023.101892","volume":"51","author":"Wang","year":"2023","journal-title":"Nano Today"}],"updated-by":[{"DOI":"10.1039\/d4bm90084g","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000}}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/BM\/D3BM02121A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:31:27Z","timestamp":1782887487000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/12\/9\/2331-2340\/796677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":39,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,4,30]]}},"URL":"https:\/\/doi.org\/10.1039\/d3bm02121a","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}