{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:30:17Z","timestamp":1789587017468,"version":"build-2803163510"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"44","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"am","delay-in-days":481,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100003977","name":"Israel Science Foundation","doi-asserted-by":"publisher","award":["1388\/22"],"award-info":[{"award-number":["1388\/22"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Commun."],"abstract":"<jats:p>Salmon calcitonin (sCT) is a polypeptide hormone available in the clinic.<\/jats:p>","DOI":"10.1039\/d3cc01140b","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T03:08:22Z","timestamp":1682478502000},"page":"6682-6685","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Enhancing the gastrointestinal stability of salmon calcitonin through peptide stapling"],"prefix":"10.1039","volume":"59","author":[{"given":"Hiba","family":"Ghareeb","sequence":"first","affiliation":[{"name":"Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6373-9318","authenticated-orcid":false,"given":"Norman","family":"Metanis","sequence":"additional","affiliation":[{"name":"Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel"},{"name":"Casali Center for Applied Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel"},{"name":"The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D3CC01140B\/cit1\/1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1146\/annurev.ph.32.030170.000425","volume":"32","author":"Copp","year":"1970","journal-title":"Annu. Rev. Physiol."},{"key":"D3CC01140B\/cit2\/1","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1016\/0002-9343(93)90382-Y","volume":"95","author":"Reginster","year":"1993","journal-title":"Am. J. Med."},{"key":"D3CC01140B\/cit3\/1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/BF00301940","volume":"57","author":"Azria","year":"1995","journal-title":"Calcif. Tissue Int."},{"key":"D3CC01140B\/cit4\/1","doi-asserted-by":"crossref","first-page":"24193","DOI":"10.1074\/jbc.M603528200","volume":"281","author":"Andreotti","year":"2006","journal-title":"J. Biol. Chem."},{"key":"D3CC01140B\/cit5\/1","doi-asserted-by":"crossref","first-page":"13689","DOI":"10.1074\/jbc.M116.726034","volume":"291","author":"Johansson","year":"2016","journal-title":"J. Biol. Chem."},{"key":"D3CC01140B\/cit6\/1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0169-6009(92)90894-J","volume":"16","author":"Potts Jr","year":"1992","journal-title":"Bone Miner."},{"key":"D3CC01140B\/cit7\/1","doi-asserted-by":"crossref","first-page":"35475","DOI":"10.1074\/jbc.M206039200","volume":"277","author":"Reches","year":"2002","journal-title":"J. Biol. Chem."},{"key":"D3CC01140B\/cit8\/1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0002-9343(00)00490-3","volume":"109","author":"Chesnut III","year":"2000","journal-title":"Am. J. Med."},{"key":"D3CC01140B\/cit9\/1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/BF00308314","volume":"52","author":"Wimalawansa","year":"1993","journal-title":"Calcif. Tissue Int."},{"key":"D3CC01140B\/cit10\/1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00315432","volume":"41","author":"W\u00fcster","year":"1991","journal-title":"Eur. J. Clin. Pharm."},{"key":"D3CC01140B\/cit11\/1","first-page":"600","volume":"20","author":"Srinivasan","year":"2020","journal-title":"J. Musculoskeletal Neuronal Interact."},{"key":"D3CC01140B\/cit12\/1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.2165\/00063030-200519030-00003","volume":"19","author":"Hamman","year":"2005","journal-title":"BioDrugs"},{"key":"D3CC01140B\/cit13\/1","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1021\/mp500809f","volume":"12","author":"Wang","year":"2015","journal-title":"Mol. Pharmacol."},{"key":"D3CC01140B\/cit14\/1","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.joca.2009.08.004","volume":"18","author":"Karsdal","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"D3CC01140B\/cit15\/1","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.joca.2014.12.019","volume":"23","author":"Karsdal","year":"2015","journal-title":"Osteoarthritis Cartilage"},{"key":"D3CC01140B\/cit16\/1","doi-asserted-by":"crossref","first-page":"7264","DOI":"10.1158\/1078-0432.CCR-07-2184","volume":"13","author":"Verdine","year":"2007","journal-title":"Clin. Cancer Res."},{"key":"D3CC01140B\/cit17\/1","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1021\/cb300515u","volume":"8","author":"Bock","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"D3CC01140B\/cit18\/1","doi-asserted-by":"crossref","first-page":"5891","DOI":"10.1021\/ja000563a","volume":"122","author":"Schafmeister","year":"2000","journal-title":"J. Am. Chem. Soc."},{"key":"D3CC01140B\/cit19\/1","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1039\/C4SC00045E","volume":"5","author":"Lau","year":"2014","journal-title":"Chem. Sci."},{"key":"D3CC01140B\/cit20\/1","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.1021\/jm4011675","volume":"57","author":"Walensky","year":"2014","journal-title":"J. Med. Chem."},{"key":"D3CC01140B\/cit21\/1","doi-asserted-by":"crossref","first-page":"7914","DOI":"10.1039\/C9CC04022F","volume":"55","author":"Charoenpattarapreeda","year":"2019","journal-title":"Chem. Commun."},{"key":"D3CC01140B\/cit22\/1","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1021\/cb501020r","volume":"10","author":"Cromm","year":"2015","journal-title":"ACS Chem. Biol."},{"key":"D3CC01140B\/cit23\/1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1021\/ja9611654","volume":"119","author":"Phelan","year":"1997","journal-title":"J. Am. Chem. Soc."},{"key":"D3CC01140B\/cit24\/1","doi-asserted-by":"crossref","first-page":"10079","DOI":"10.1021\/acs.chemrev.0c00532","volume":"120","author":"Li","year":"2020","journal-title":"Chem. Rev."},{"key":"D3CC01140B\/cit25\/1","doi-asserted-by":"crossref","first-page":"7927","DOI":"10.1039\/D0SC02374D","volume":"11","author":"Zhao","year":"2020","journal-title":"Chem. Sci."},{"key":"D3CC01140B\/cit26\/1","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1021\/acs.jmedchem.1c01744","volume":"65","author":"Luong","year":"2022","journal-title":"J. Med. Chem."},{"key":"D3CC01140B\/cit27\/1","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1021\/ja00897a025","volume":"85","author":"Merrifield","year":"1963","journal-title":"J. Am. Chem. Soc."},{"key":"D3CC01140B\/cit28\/1","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.cbpa.2008.08.032","volume":"12","author":"Lees","year":"2008","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D3CC01140B\/cit29\/1","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1002\/anie.201109129","volume":"51","author":"Metanis","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3CC01140B\/cit30\/1","doi-asserted-by":"crossref","first-page":"7007","DOI":"10.1039\/C6SC02285E","volume":"7","author":"Kourra","year":"2016","journal-title":"Chem. Sci."},{"key":"D3CC01140B\/cit31\/1","doi-asserted-by":"crossref","first-page":"4814","DOI":"10.1039\/C8SC01110A","volume":"9","author":"Mousa","year":"2018","journal-title":"Chem. Sci."},{"key":"D3CC01140B\/cit32\/1","doi-asserted-by":"crossref","first-page":"8513","DOI":"10.1002\/chem.201900892","volume":"25","author":"Weil-Ktorza","year":"2019","journal-title":"Chem. \u2013 Eur. J."},{"key":"D3CC01140B\/cit33\/1","doi-asserted-by":"crossref","first-page":"eaan3398","DOI":"10.1126\/scisignal.aan3398","volume":"10","author":"Muttenthaler","year":"2017","journal-title":"Sci. Sign."},{"key":"D3CC01140B\/cit34\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s42004-021-00463-9","volume":"4","author":"Mousa","year":"2021","journal-title":"Commun. Chem."},{"key":"D3CC01140B\/cit35\/1","doi-asserted-by":"crossref","first-page":"8585","DOI":"10.1021\/jm100989w","volume":"53","author":"Muttenthaler","year":"2010","journal-title":"J. Med. Chem."},{"key":"D3CC01140B\/cit36\/1","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/cbic.200390030","volume":"4","author":"Bondebjerg","year":"2003","journal-title":"ChemBioChem"},{"key":"D3CC01140B\/cit37\/1","doi-asserted-by":"crossref","first-page":"5946","DOI":"10.1021\/ja400119t","volume":"135","author":"Spokoyny","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"D3CC01140B\/cit38\/1","doi-asserted-by":"crossref","first-page":"15094","DOI":"10.1021\/jacs.5b10779","volume":"137","author":"Zheng","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"D3CC01140B\/cit39\/1","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1002\/asia.202000609","volume":"15","author":"Qi","year":"2020","journal-title":"Chem. \u2013 Asian J."},{"key":"D3CC01140B\/cit40\/1","doi-asserted-by":"crossref","first-page":"8071","DOI":"10.1021\/acs.jmedchem.7b00813","volume":"60","author":"Klein","year":"2017","journal-title":"J. Med. Chem."},{"key":"D3CC01140B\/cit41\/1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/bip.10203","volume":"66","author":"Taylor","year":"2002","journal-title":"Pep. Sci."},{"key":"D3CC01140B\/cit42\/1","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1021\/jm010474o","volume":"45","author":"Taylor","year":"2002","journal-title":"J. Med. Chem."},{"key":"D3CC01140B\/cit43\/1","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1016\/0040-4039(95)00449-M","volume":"36","author":"Beugelmans","year":"1995","journal-title":"Tetrahedron Lett."},{"key":"D3CC01140B\/cit44\/1","doi-asserted-by":"crossref","first-page":"6646","DOI":"10.1002\/anie.202016267","volume":"60","author":"Li","year":"2021","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3CC01140B\/cit45\/1","first-page":"1","volume":"13","author":"Li","year":"2022","journal-title":"Nat. Commun."},{"key":"D3CC01140B\/cit46\/1","doi-asserted-by":"crossref","first-page":"9416","DOI":"10.1021\/jo0348874","volume":"68","author":"Bartoli","year":"2003","journal-title":"J. Org. Chem."},{"key":"D3CC01140B\/cit47\/1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/ng1096-141","volume":"14","author":"Whitcomb","year":"1996","journal-title":"Nat. Genet."},{"key":"D3CC01140B\/cit48\/1","first-page":"117","volume":"4","author":"Masi","year":"2007","journal-title":"Clin. Rev. Bone Miner. Metab."},{"key":"D3CC01140B\/cit49\/1","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/bjc.1977.119","volume":"35","author":"Hunt","year":"1977","journal-title":"Br. J. Cancer"},{"key":"D3CC01140B\/cit50\/1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1046\/j.1365-2613.2000.00176.x","volume":"81","author":"Pondel","year":"2000","journal-title":"Int. J. Exp. Pathol."},{"key":"D3CC01140B\/cit51\/1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1177\/2472630318754828","volume":"23","author":"Mella","year":"2018","journal-title":"SLAS Technol."},{"key":"D3CC01140B\/cit52\/1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1054\/ceca.1999.0095","volume":"27","author":"Gee","year":"2000","journal-title":"Cell Calcium"}],"container-title":["Chemical Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/CC\/D3CC01140B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T17:48:18Z","timestamp":1783532898000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cc\/article\/59\/44\/6682-6685\/797354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":52,"journal-issue":{"issue":"44","published-print":{"date-parts":[[2023,5,30]]}},"URL":"https:\/\/doi.org\/10.1039\/d3cc01140b","relation":{},"ISSN":["1359-7345","1364-548X"],"issn-type":[{"value":"1359-7345","type":"print"},{"value":"1364-548X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}