{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:34:27Z","timestamp":1790886867115,"version":"4.1.0"},"reference-count":219,"publisher":"Royal Society of Chemistry (RSC)","issue":"13","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"am","delay-in-days":530,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA218600"],"award-info":[{"award-number":["R01CA218600"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA230854"],"award-info":[{"award-number":["R01CA230854"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA260666"],"award-info":[{"award-number":["R01CA260666"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA268384"],"award-info":[{"award-number":["R01CA268384"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA268519"],"award-info":[{"award-number":["R01CA268519"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["T32CA078207"],"award-info":[{"award-number":["T32CA078207"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Soc. Rev."],"abstract":"<jats:p>This review summarizes the past and present advances in developing degraders of epigenetic targets which play critical roles in many crucial biological pathways and therefore, targeted for the discovery of therapeutics.<\/jats:p>","DOI":"10.1039\/d3cs00100h","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T10:16:40Z","timestamp":1686737800000},"page":"4313-4342","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Chemically induced degradation of epigenetic targets"],"prefix":"10.1039","volume":"52","author":[{"given":"Md","family":"Kabir","sequence":"first","affiliation":[{"name":"Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xufen","family":"Yu","sequence":"additional","affiliation":[{"name":"Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5327-832X","authenticated-orcid":false,"given":"H. \u00dcmit","family":"Kaniskan","sequence":"additional","affiliation":[{"name":"Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2387-3862","authenticated-orcid":false,"given":"Jian","family":"Jin","sequence":"additional","affiliation":[{"name":"Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D3CS00100H\/cit1\/1","first-page":"18","volume":"1","author":"Waddington","year":"1942","journal-title":"Endeavour"},{"key":"D3CS00100H\/cit2\/1","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1126\/science.187.4173.226","volume":"187","author":"Holliday","year":"1975","journal-title":"Science"},{"key":"D3CS00100H\/cit3\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/38444","volume":"389","author":"Luger","year":"1997","journal-title":"Nature"},{"key":"D3CS00100H\/cit4\/1","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1073\/pnas.51.5.786","volume":"51","author":"Allfrey","year":"1964","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit5\/1","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/20974","volume":"399","author":"Dhalluin","year":"1999","journal-title":"Nature"},{"key":"D3CS00100H\/cit6\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/47412","volume":"403","author":"Strahl","year":"2000","journal-title":"Nature"},{"key":"D3CS00100H\/cit7\/1","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1126\/science.1063127","volume":"293","author":"Jenuwein","year":"2001","journal-title":"Science"},{"key":"D3CS00100H\/cit8\/1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nrd4360","volume":"13","author":"Falkenberg","year":"2014","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D3CS00100H\/cit9\/1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.jprot.2016.10.003","volume":"150","author":"Gil","year":"2017","journal-title":"J. Proteomics"},{"key":"D3CS00100H\/cit10\/1","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.2174\/1568026619666181120150122","volume":"18","author":"Zhou","year":"2018","journal-title":"Curr. Top. Med. Chem."},{"key":"D3CS00100H\/cit11\/1","doi-asserted-by":"crossref","first-page":"576391","DOI":"10.3389\/fcell.2020.576391","volume":"8","author":"Chen","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"D3CS00100H\/cit12\/1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3389\/fgene.2014.00364","volume":"5","author":"Byrne","year":"2014","journal-title":"Front. Genet."},{"key":"D3CS00100H\/cit13\/1","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/nrc3599","volume":"13","author":"Holohan","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"D3CS00100H\/cit14\/1","doi-asserted-by":"crossref","first-page":"4512","DOI":"10.1182\/blood-2012-08-450494","volume":"121","author":"Yan","year":"2013","journal-title":"Blood"},{"key":"D3CS00100H\/cit15\/1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/s41556-022-00850-x","volume":"24","author":"Wang","year":"2022","journal-title":"Nat. Cell Biol."},{"key":"D3CS00100H\/cit16\/1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nrd.2016.211","volume":"16","author":"Lai","year":"2017","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D3CS00100H\/cit17\/1","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/s41573-019-0047-y","volume":"18","author":"Schapira","year":"2019","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D3CS00100H\/cit18\/1","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/s41568-021-00365-x","volume":"21","author":"Dale","year":"2021","journal-title":"Nat. Rev. Cancer"},{"key":"D3CS00100H\/cit19\/1","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nchembio.2329","volume":"13","author":"Gadd","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit20\/1","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1038\/s41589-018-0055-y","volume":"14","author":"Nowak","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit21\/1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.chembiol.2017.09.010","volume":"25","author":"Bondeson","year":"2018","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit22\/1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.chembiol.2017.10.005","volume":"25","author":"Huang","year":"2018","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit23\/1","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1016\/j.chembiol.2021.07.002","volume":"28","author":"Xiong","year":"2021","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit24\/1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.chembiol.2017.09.009","volume":"25","author":"Burslem","year":"2018","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit25\/1","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1038\/s41591-019-0668-z","volume":"25","author":"Khan","year":"2019","journal-title":"Nat. Med."},{"key":"D3CS00100H\/cit26\/1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.cbpa.2019.02.022","volume":"50","author":"Paiva","year":"2019","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D3CS00100H\/cit27\/1","doi-asserted-by":"crossref","first-page":"128653","DOI":"10.1016\/j.bmcl.2022.128653","volume":"63","author":"Webb","year":"2022","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D3CS00100H\/cit28\/1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cbpa.2020.01.010","volume":"57","author":"Vogelmann","year":"2020","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D3CS00100H\/cit29\/1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/nm.4036","volume":"22","author":"Kim","year":"2016","journal-title":"Nat. Med."},{"key":"D3CS00100H\/cit30\/1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/aps.2013.161","volume":"35","author":"Tan","year":"2014","journal-title":"Acta Pharmacol. Sin."},{"key":"D3CS00100H\/cit31\/1","doi-asserted-by":"crossref","first-page":"5323","DOI":"10.1093\/emboj\/cdg542","volume":"22","author":"Bracken","year":"2003","journal-title":"EMBO J."},{"key":"D3CS00100H\/cit32\/1","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1200\/JCO.2005.01.5180","volume":"24","author":"Bachmann","year":"2006","journal-title":"J. Clin. Oncol."},{"key":"D3CS00100H\/cit33\/1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s13045-020-00937-8","volume":"13","author":"Duan","year":"2020","journal-title":"J. Hematol. Oncol."},{"key":"D3CS00100H\/cit34\/1","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1021\/cb400133j","volume":"8","author":"Konze","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"D3CS00100H\/cit35\/1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/s41589-019-0421-4","volume":"16","author":"Ma","year":"2020","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit36\/1","doi-asserted-by":"crossref","first-page":"7922","DOI":"10.1073\/pnas.1303800110","volume":"110","author":"Knutson","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit37\/1","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1021\/acs.jmedchem.0c02234","volume":"64","author":"Liu","year":"2021","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit38\/1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nature13527","volume":"512","author":"Fischer","year":"2014","journal-title":"Nature"},{"key":"D3CS00100H\/cit39\/1","doi-asserted-by":"crossref","first-page":"10167","DOI":"10.1021\/acs.jmedchem.1c00460","volume":"64","author":"Tu","year":"2021","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit40\/1","doi-asserted-by":"crossref","first-page":"114462","DOI":"10.1016\/j.ejmech.2022.114462","volume":"238","author":"Wang","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"D3CS00100H\/cit41\/1","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1021\/acsptsci.2c00100","volume":"5","author":"Dale","year":"2022","journal-title":"ACS Pharmacol. Transl. Sci."},{"key":"D3CS00100H\/cit42\/1","doi-asserted-by":"crossref","first-page":"4237","DOI":"10.1093\/nar\/gkr1235","volume":"40","author":"Zhang","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"D3CS00100H\/cit43\/1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/nrc3929","volume":"15","author":"Rao","year":"2015","journal-title":"Nat. Rev. Cancer"},{"key":"D3CS00100H\/cit44\/1","doi-asserted-by":"crossref","first-page":"27275","DOI":"10.1074\/jbc.M112.364125","volume":"287","author":"Dharmarajan","year":"2012","journal-title":"J. Biol. Chem."},{"key":"D3CS00100H\/cit45\/1","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/nrc2253","volume":"7","author":"Krivtsov","year":"2007","journal-title":"Nat. Rev. Cancer"},{"key":"D3CS00100H\/cit46\/1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.celrep.2016.05.063","volume":"16","author":"Carugo","year":"2016","journal-title":"Cell Rep."},{"key":"D3CS00100H\/cit47\/1","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1021\/ja306028q","volume":"135","author":"Karatas","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit48\/1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1042\/BJ20121280","volume":"449","author":"Senisterra","year":"2013","journal-title":"Biochem. J."},{"key":"D3CS00100H\/cit49\/1","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/nchembio.1859","volume":"11","author":"Grebien","year":"2015","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit50\/1","doi-asserted-by":"crossref","first-page":"10682","DOI":"10.1021\/acs.jmedchem.1c00146","volume":"64","author":"D\u00f6lle","year":"2021","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit51\/1","doi-asserted-by":"crossref","first-page":"eabj1578","DOI":"10.1126\/scitranslmed.abj1578","volume":"13","author":"Yu","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"D3CS00100H\/cit52\/1","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.1038\/s41388-022-02340-8","volume":"41","author":"Li","year":"2022","journal-title":"Oncogene"},{"issue":"6","key":"D3CS00100H\/cit53\/1","doi-asserted-by":"crossref","first-page":"a026708","DOI":"10.1101\/cshperspect.a026708","volume":"7","author":"Bennett","year":"2017","journal-title":"Cold Spring Harbor Perspect. Med."},{"key":"D3CS00100H\/cit54\/1","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1128\/MCB.01341-10","volume":"31","author":"Rahman","year":"2011","journal-title":"Mol. Cell. Biol."},{"key":"D3CS00100H\/cit55\/1","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1038\/ncb1608","volume":"9","author":"Wang","year":"2007","journal-title":"Nat. Cell Biol."},{"key":"D3CS00100H\/cit56\/1","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.molonc.2016.02.003","volume":"10","author":"Irish","year":"2016","journal-title":"Mol. Oncol."},{"key":"D3CS00100H\/cit57\/1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/s41586-020-03170-y","volume":"590","author":"Yuan","year":"2021","journal-title":"Nature"},{"key":"D3CS00100H\/cit58\/1","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1182\/blood-2002-06-1675","volume":"101","author":"Keats","year":"2003","journal-title":"Blood"},{"key":"D3CS00100H\/cit59\/1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.molcel.2011.08.042","volume":"44","author":"Kuo","year":"2011","journal-title":"Mol. Cell"},{"key":"D3CS00100H\/cit60\/1","doi-asserted-by":"crossref","first-page":"4843","DOI":"10.1038\/s41467-019-12811-4","volume":"10","author":"Lhoumaud","year":"2019","journal-title":"Nat. Commun."},{"key":"D3CS00100H\/cit61\/1","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/s41589-019-0310-x","volume":"15","author":"B\u00f6ttcher","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit62\/1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.chembiol.2021.08.004","volume":"29","author":"Xu","year":"2022","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit63\/1","doi-asserted-by":"crossref","first-page":"114528","DOI":"10.1016\/j.ejmech.2022.114528","volume":"239","author":"Sun","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"D3CS00100H\/cit64\/1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/s41589-021-00898-0","volume":"18","author":"Dilworth","year":"2022","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit65\/1","doi-asserted-by":"crossref","first-page":"10611","DOI":"10.1021\/acs.jmedchem.2c00807","volume":"65","author":"Meng","year":"2022","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit66\/1","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1021\/acschembio.7b00969","volume":"13","author":"Ishoey","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"D3CS00100H\/cit67\/1","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1007\/s00018-015-1847-9","volume":"72","author":"Stopa","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"key":"D3CS00100H\/cit68\/1","doi-asserted-by":"crossref","first-page":"17960","DOI":"10.1073\/pnas.1209814109","volume":"109","author":"Antonysamy","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit69\/1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nrc3409","volume":"13","author":"Yang","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"D3CS00100H\/cit70\/1","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/leu.2017.334","volume":"32","author":"Gull\u00e0","year":"2018","journal-title":"Leukemia"},{"key":"D3CS00100H\/cit71\/1","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/nchembio.1810","volume":"11","author":"Chan-Penebre","year":"2015","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit72\/1","doi-asserted-by":"crossref","first-page":"9977","DOI":"10.1021\/acs.jmedchem.0c01111","volume":"63","author":"Shen","year":"2020","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit73\/1","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1021\/cr500452k","volume":"115","author":"Dancy","year":"2015","journal-title":"Chem. Rev."},{"key":"D3CS00100H\/cit74\/1","doi-asserted-by":"crossref","first-page":"102255","DOI":"10.1016\/j.cbpa.2022.102255","volume":"72","author":"Whedon","year":"2023","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D3CS00100H\/cit75\/1","doi-asserted-by":"crossref","first-page":"3832","DOI":"10.1128\/MCB.22.11.3832-3841.2002","volume":"22","author":"Ludlam","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"D3CS00100H\/cit76\/1","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature06546","volume":"451","author":"Liu","year":"2008","journal-title":"Nature"},{"key":"D3CS00100H\/cit77\/1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3389\/fonc.2015.00108","volume":"5","author":"Sun","year":"2015","journal-title":"Front Oncol."},{"issue":"3","key":"D3CS00100H\/cit78\/1","doi-asserted-by":"crossref","first-page":"a026534","DOI":"10.1101\/cshperspect.a026534","volume":"7","author":"Attar","year":"2017","journal-title":"Cold Spring Harbor Perspect. Med."},{"key":"D3CS00100H\/cit79\/1","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1093\/emboj\/19.4.662","volume":"19","author":"Mart\u00ednez-Balb\u00e1s","year":"2000","journal-title":"EMBO J."},{"key":"D3CS00100H\/cit80\/1","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1021\/acs.jmedchem.6b01566","volume":"60","author":"Humphreys","year":"2017","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit81\/1","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1021\/acschembio.8b00705","volume":"13","author":"Bassi","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"D3CS00100H\/cit82\/1","doi-asserted-by":"crossref","first-page":"9162","DOI":"10.1021\/acs.jmedchem.7b00796","volume":"60","author":"Romero","year":"2017","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit83\/1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.chembiol.2020.12.004","volume":"28","author":"Vannam","year":"2021","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit84\/1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1021\/acsmedchemlett.7b00395","volume":"9","author":"Michaelides","year":"2018","journal-title":"ACS Med. Chem. Lett."},{"key":"D3CS00100H\/cit85\/1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1158\/2159-8290.CD-21-0385","volume":"12","author":"Durbin","year":"2022","journal-title":"Cancer Discovery"},{"key":"D3CS00100H\/cit86\/1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0014-5793(01)03309-9","volume":"513","author":"Zeng","year":"2002","journal-title":"FEBS Lett."},{"key":"D3CS00100H\/cit87\/1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.cell.2012.02.013","volume":"149","author":"Filippakopoulos","year":"2012","journal-title":"Cell"},{"key":"D3CS00100H\/cit88\/1","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/nrm.2016.143","volume":"18","author":"Fujisawa","year":"2017","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"D3CS00100H\/cit89\/1","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1002\/hep.26540","volume":"58","author":"Cleary","year":"2013","journal-title":"Hepatology"},{"key":"D3CS00100H\/cit90\/1","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1182\/blood-2013-10-531509","volume":"123","author":"Odejide","year":"2014","journal-title":"Blood"},{"key":"D3CS00100H\/cit91\/1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s13402-014-0209-1","volume":"37","author":"Oh","year":"2014","journal-title":"Cell. Oncol."},{"key":"D3CS00100H\/cit92\/1","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1038\/emboj.2010.176","volume":"29","author":"Reynoird","year":"2010","journal-title":"EMBO J."},{"key":"D3CS00100H\/cit93\/1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1158\/2159-8290.CD-15-1335","volume":"6","author":"Stathis","year":"2016","journal-title":"Cancer Discovery"},{"key":"D3CS00100H\/cit94\/1","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1038\/s41416-021-01321-0","volume":"124","author":"Shorstova","year":"2021","journal-title":"Br. J. Cancer"},{"key":"D3CS00100H\/cit95\/1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nature14898","volume":"525","author":"Rathert","year":"2015","journal-title":"Nature"},{"key":"D3CS00100H\/cit96\/1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nature16508","volume":"529","author":"Shu","year":"2016","journal-title":"Nature"},{"key":"D3CS00100H\/cit97\/1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ddtec.2019.04.001","volume":"31","author":"Yang","year":"2019","journal-title":"Drug Discovery Today: Technol."},{"key":"D3CS00100H\/cit98\/1","doi-asserted-by":"crossref","first-page":"117033","DOI":"10.1016\/j.bmc.2022.117033","volume":"73","author":"Zhou","year":"2022","journal-title":"Bioorg. Med. Chem."},{"key":"D3CS00100H\/cit99\/1","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1021\/acschembio.5b00216","volume":"10","author":"Zengerle","year":"2015","journal-title":"ACS Chem. Biol."},{"key":"D3CS00100H\/cit100\/1","doi-asserted-by":"crossref","first-page":"7124","DOI":"10.1073\/pnas.1521738113","volume":"113","author":"Raina","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit101\/1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1021\/acs.jmedchem.6b01912","volume":"61","author":"Chan","year":"2018","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit102\/1","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1038\/s41388-021-01783-9","volume":"40","author":"Pietrobono","year":"2021","journal-title":"Oncogene"},{"key":"D3CS00100H\/cit103\/1","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1126\/science.aab1433","volume":"348","author":"Winter","year":"2015","journal-title":"Science"},{"key":"D3CS00100H\/cit104\/1","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.chembiol.2015.05.009","volume":"22","author":"Lu","year":"2015","journal-title":"Chem. Biol."},{"key":"D3CS00100H\/cit105\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.molcel.2017.06.004","volume":"67","author":"Winter","year":"2017","journal-title":"Mol. Cell"},{"key":"D3CS00100H\/cit106\/1","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1021\/acs.jmedchem.6b01816","volume":"61","author":"Zhou","year":"2018","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit107\/1","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1158\/0008-5472.CAN-16-2622","volume":"77","author":"Bai","year":"2017","journal-title":"Cancer Res."},{"key":"D3CS00100H\/cit108\/1","doi-asserted-by":"crossref","first-page":"6685","DOI":"10.1021\/acs.jmedchem.8b00506","volume":"61","author":"Qin","year":"2018","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit109\/1","doi-asserted-by":"crossref","first-page":"105238","DOI":"10.1016\/j.bioorg.2021.105238","volume":"115","author":"Xiang","year":"2021","journal-title":"Bioorg. Chem."},{"key":"D3CS00100H\/cit110\/1","first-page":"5728","volume":"11","author":"Lu","year":"2019","journal-title":"Am. J. Transl. Res."},{"key":"D3CS00100H\/cit111\/1","doi-asserted-by":"crossref","first-page":"4927","DOI":"10.1021\/acs.jmedchem.5b00613","volume":"58","author":"Ran","year":"2015","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit112\/1","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.str.2007.08.007","volume":"15","author":"Han","year":"2007","journal-title":"Structure"},{"key":"D3CS00100H\/cit113\/1","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nature08398","volume":"461","author":"Margueron","year":"2009","journal-title":"Nature"},{"key":"D3CS00100H\/cit114\/1","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00432-014-1854-5","volume":"141","author":"Liu","year":"2015","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"D3CS00100H\/cit115\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/00498254.2021.2005852","volume":"52","author":"Zhang","year":"2022","journal-title":"Xenobiotica"},{"key":"D3CS00100H\/cit116\/1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nchembio.2304","volume":"13","author":"Qi","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit117\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.chembiol.2019.11.006","volume":"27","author":"Potjewyd","year":"2020","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit118\/1","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1021\/acs.jmedchem.6b01576","volume":"60","author":"Huang","year":"2017","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit119\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.chembiol.2019.11.004","volume":"27","author":"Hsu","year":"2020","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit120\/1","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1038\/ncomms4127","volume":"5","author":"Cao","year":"2014","journal-title":"Nat. Commun."},{"key":"D3CS00100H\/cit121\/1","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/nchembio.2007","volume":"12","author":"Stuckey","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit122\/1","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1002\/stem.1035","volume":"30","author":"Siddique","year":"2012","journal-title":"Stem Cells"},{"key":"D3CS00100H\/cit123\/1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.celrep.2015.12.034","volume":"14","author":"van den Boom","year":"2016","journal-title":"Cell Rep."},{"key":"D3CS00100H\/cit124\/1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/nm.3418","volume":"20","author":"Kreso","year":"2014","journal-title":"Nat. Med."},{"key":"D3CS00100H\/cit125\/1","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1038\/s41589-021-00815-5","volume":"17","author":"Shukla","year":"2021","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit126\/1","doi-asserted-by":"crossref","first-page":"e2205573","DOI":"10.1002\/advs.202205573","volume":"10","author":"Park","year":"2023","journal-title":"Adv. Sci."},{"key":"D3CS00100H\/cit127\/1","doi-asserted-by":"crossref","first-page":"22622","DOI":"10.1021\/jacs.2c09255","volume":"144","author":"Xiong","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit128\/1","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/nature09542","volume":"468","author":"Tsai","year":"2010","journal-title":"Nature"},{"key":"D3CS00100H\/cit129\/1","doi-asserted-by":"crossref","first-page":"11612","DOI":"10.1073\/pnas.0813177106","volume":"106","author":"Allton","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit130\/1","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/onc.2013.593","volume":"34","author":"Zhang","year":"2015","journal-title":"Oncogene"},{"key":"D3CS00100H\/cit131\/1","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1021\/acs.jmedchem.5b00405","volume":"59","author":"Palmer","year":"2016","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit132\/1","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1021\/acs.jmedchem.5b00458","volume":"59","author":"Bennett","year":"2016","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit133\/1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/s41589-018-0010-y","volume":"14","author":"Gechijian","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit134\/1","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/ng.2628","volume":"45","author":"Kadoch","year":"2013","journal-title":"Nat. Genet."},{"key":"D3CS00100H\/cit135\/1","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1038\/s41467-019-09891-7","volume":"10","author":"Wang","year":"2019","journal-title":"Nat. Commun."},{"key":"D3CS00100H\/cit136\/1","doi-asserted-by":"crossref","first-page":"32254","DOI":"10.1074\/jbc.M806061200","volume":"283","author":"Kaeser","year":"2008","journal-title":"J. Biol. Chem."},{"key":"D3CS00100H\/cit137\/1","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/nchembio.2115","volume":"12","author":"Hohmann","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit138\/1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/s41419-019-1570-9","volume":"10","author":"Del Gaudio","year":"2019","journal-title":"Cell Death Dis."},{"key":"D3CS00100H\/cit139\/1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1476-4598-7-58","volume":"7","author":"Scotto","year":"2008","journal-title":"Mol. Cancer"},{"key":"D3CS00100H\/cit140\/1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.canlet.2019.01.007","volume":"446","author":"Huang","year":"2019","journal-title":"Cancer Lett."},{"key":"D3CS00100H\/cit141\/1","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1158\/0008-5472.CAN-20-1417","volume":"81","author":"Alpsoy","year":"2021","journal-title":"Cancer Res."},{"key":"D3CS00100H\/cit142\/1","doi-asserted-by":"crossref","first-page":"4462","DOI":"10.1021\/acs.jmedchem.5b01865","volume":"59","author":"Martin","year":"2016","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit143\/1","doi-asserted-by":"crossref","first-page":"5738","DOI":"10.1002\/anie.201611281","volume":"56","author":"Remillard","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3CS00100H\/cit144\/1","doi-asserted-by":"crossref","first-page":"e41305","DOI":"10.7554\/eLife.41305","volume":"7","author":"Brien","year":"2018","journal-title":"eLife"},{"key":"D3CS00100H\/cit145\/1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1021\/acs.jmedchem.8b01413","volume":"62","author":"Zoppi","year":"2019","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit146\/1","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1002\/cbic.200600562","volume":"8","author":"Singh","year":"2007","journal-title":"ChemBioChem"},{"key":"D3CS00100H\/cit147\/1","doi-asserted-by":"crossref","first-page":"10067","DOI":"10.1074\/jbc.M808782200","volume":"284","author":"Flowers","year":"2009","journal-title":"J. Biol. Chem."},{"key":"D3CS00100H\/cit148\/1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nrc3068","volume":"11","author":"Wilson","year":"2011","journal-title":"Nat. Rev. Cancer"},{"key":"D3CS00100H\/cit149\/1","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1128\/MCB.01372-13","volume":"34","author":"Wilson","year":"2014","journal-title":"Mol. Cell. Biol."},{"key":"D3CS00100H\/cit150\/1","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.1073\/pnas.1316793111","volume":"111","author":"Hoffman","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit151\/1","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/s41589-019-0294-6","volume":"15","author":"Farnaby","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit152\/1","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/s41586-021-04246-z","volume":"601","author":"Xiao","year":"2022","journal-title":"Nature"},{"key":"D3CS00100H\/cit153\/1","doi-asserted-by":"crossref","first-page":"5095","DOI":"10.1021\/acs.jmedchem.5b01997","volume":"59","author":"Sutherell","year":"2016","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit154\/1","doi-asserted-by":"crossref","first-page":"5969","DOI":"10.1038\/s41467-022-33430-6","volume":"13","author":"Kofink","year":"2022","journal-title":"Nat. Commun."},{"key":"D3CS00100H\/cit155\/1","doi-asserted-by":"crossref","first-page":"6814","DOI":"10.1038\/s41467-022-34562-5","volume":"13","author":"Cantley","year":"2022","journal-title":"Nat. Commun."},{"key":"D3CS00100H\/cit156\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1139\/O08-111","volume":"87","author":"Schulze","year":"2009","journal-title":"Biochem. Cell Biol."},{"key":"D3CS00100H\/cit157\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/nature21687","volume":"543","author":"Wan","year":"2017","journal-title":"Nature"},{"key":"D3CS00100H\/cit158\/1","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nchembio.2065","volume":"12","author":"Andrews","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit159\/1","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.1182\/blood-2007-05-090514","volume":"110","author":"Mueller","year":"2007","journal-title":"Blood"},{"key":"D3CS00100H\/cit160\/1","first-page":"E636","volume":"108","author":"He","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3CS00100H\/cit161\/1","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1101\/gad.1195504","volume":"18","author":"Daser","year":"2004","journal-title":"Genes Dev."},{"key":"D3CS00100H\/cit162\/1","doi-asserted-by":"crossref","first-page":"16302","DOI":"10.1002\/anie.201810617","volume":"57","author":"Moustakim","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3CS00100H\/cit163\/1","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1038\/s41589-018-0144-y","volume":"14","author":"Li","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit164\/1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/2472555218809904","volume":"24","author":"Christott","year":"2019","journal-title":"SLAS Discovery"},{"key":"D3CS00100H\/cit165\/1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/nature21688","volume":"543","author":"Erb","year":"2017","journal-title":"Nature"},{"key":"D3CS00100H\/cit166\/1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/s41589-018-0021-8","volume":"14","author":"Nabet","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit167\/1","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1021\/acscentsci.0c01550","volume":"7","author":"Garnar-Wortzel","year":"2021","journal-title":"ACS Cent. Sci."},{"key":"D3CS00100H\/cit168\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s13045-022-01258-8","volume":"15","author":"Li","year":"2022","journal-title":"J. Hematol. Oncol."},{"key":"D3CS00100H\/cit169\/1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0959-437X(00)00174-X","volume":"11","author":"Khochbin","year":"2001","journal-title":"Curr. Opin. Genet. Dev."},{"key":"D3CS00100H\/cit170\/1","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1093\/nar\/25.18.3693","volume":"25","author":"Leipe","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"D3CS00100H\/cit171\/1","doi-asserted-by":"crossref","first-page":"a018713","DOI":"10.1101\/cshperspect.a018713","volume":"6","author":"Seto","year":"2014","journal-title":"Cold Spring Harbor Perspect. Biol."},{"key":"D3CS00100H\/cit172\/1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1101\/gad.552310","volume":"24","author":"Yamaguchi","year":"2010","journal-title":"Genes Dev."},{"issue":"10","key":"D3CS00100H\/cit173\/1","doi-asserted-by":"crossref","first-page":"a026831","DOI":"10.1101\/cshperspect.a026831","volume":"6","author":"Li","year":"2016","journal-title":"Cold Spring Harbor Perspect. Med."},{"key":"D3CS00100H\/cit174\/1","doi-asserted-by":"crossref","first-page":"12460","DOI":"10.1021\/acs.jmedchem.0c00830","volume":"63","author":"Ho","year":"2020","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit175\/1","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1002\/ijc.22751","volume":"121","author":"Beckers","year":"2007","journal-title":"Int. J. Cancer"},{"key":"D3CS00100H\/cit176\/1","doi-asserted-by":"crossref","first-page":"4476","DOI":"10.1039\/D0CC01485K","volume":"56","author":"Smalley","year":"2020","journal-title":"Chem. Commun."},{"key":"D3CS00100H\/cit177\/1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.chembiol.2014.12.015","volume":"22","author":"Wang","year":"2015","journal-title":"Chem. Biol."},{"key":"D3CS00100H\/cit178\/1","doi-asserted-by":"crossref","first-page":"9866","DOI":"10.1039\/D0CC03243C","volume":"56","author":"Xiao","year":"2020","journal-title":"Chem. Commun."},{"key":"D3CS00100H\/cit179\/1","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1016\/j.bmcl.2018.05.057","volume":"28","author":"Yang","year":"2018","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D3CS00100H\/cit180\/1","doi-asserted-by":"crossref","first-page":"9891","DOI":"10.1021\/jm301098e","volume":"55","author":"Bergman","year":"2012","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit181\/1","doi-asserted-by":"crossref","first-page":"7042","DOI":"10.1021\/acs.jmedchem.9b00516","volume":"62","author":"Wu","year":"2019","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit182\/1","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1007\/s13238-018-0602-z","volume":"10","author":"An","year":"2019","journal-title":"Protein Cell"},{"key":"D3CS00100H\/cit183\/1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1021\/acsmedchemlett.0c00046","volume":"11","author":"Yang","year":"2020","journal-title":"ACS Med. Chem. Lett."},{"key":"D3CS00100H\/cit184\/1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1006\/bbrc.2000.3000","volume":"273","author":"Frye","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D3CS00100H\/cit185\/1","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1002\/ijc.33118","volume":"147","author":"Chen","year":"2020","journal-title":"Int. J. Cancer"},{"key":"D3CS00100H\/cit186\/1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1021\/acs.jmedchem.6b01872","volume":"61","author":"Schiedel","year":"2018","journal-title":"J. Med. Chem."},{"key":"D3CS00100H\/cit187\/1","doi-asserted-by":"crossref","first-page":"4083","DOI":"10.1042\/BCJ20160719","volume":"473","author":"Iconomou","year":"2016","journal-title":"Biochem. J."},{"key":"D3CS00100H\/cit188\/1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1177\/2472555220965528","volume":"26","author":"Ishida","year":"2021","journal-title":"SLAS Discovery"},{"key":"D3CS00100H\/cit189\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1158\/0008-5472.CAN-18-2918","volume":"79","author":"Hines","year":"2019","journal-title":"Cancer Res."},{"key":"D3CS00100H\/cit190\/1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1248\/cpb.c18-00567","volume":"67","author":"Ohoka","year":"2019","journal-title":"Chem. Pharm. Bull."},{"key":"D3CS00100H\/cit191\/1","doi-asserted-by":"crossref","first-page":"15073","DOI":"10.1021\/jacs.1c04841","volume":"143","author":"Wei","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit192\/1","doi-asserted-by":"crossref","first-page":"15543","DOI":"10.1038\/s41598-020-72491-9","volume":"10","author":"Tong","year":"2020","journal-title":"Sci. Rep."},{"key":"D3CS00100H\/cit193\/1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/s41392-020-00245-0","volume":"5","author":"Li","year":"2020","journal-title":"Signal Transduction Targeted Ther."},{"key":"D3CS00100H\/cit194\/1","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.1021\/acschembio.8b01083","volume":"14","author":"Ward","year":"2019","journal-title":"ACS Chem. Biol."},{"key":"D3CS00100H\/cit195\/1","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/s41589-019-0304-8","volume":"15","author":"Spradlin","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit196\/1","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.chembiol.2021.01.005","volume":"28","author":"Luo","year":"2021","journal-title":"Cell Chem. Biol."},{"key":"D3CS00100H\/cit197\/1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/s41589-019-0279-5","volume":"15","author":"Zhang","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit198\/1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1021\/jacs.1c03980","volume":"144","author":"Henning","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit199\/1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1021\/acschembio.2c00747","volume":"18","author":"Shergalis","year":"2023","journal-title":"ACS Chem. Biol."},{"key":"D3CS00100H\/cit201\/1","doi-asserted-by":"publisher","DOI":"10.1101\/2023.02.14.528208","volume-title":"bioRxiv","author":"Li","year":"2023","unstructured":"Y. D.Li ,  M. W.Ma ,  M. M.Hassan ,  M.Hunkeler ,  M.Teng ,  K.Puvar ,  R.Lumpkin ,  B.Sandoval ,  C. Y.Jin ,  S. B.Ficarro ,  M. Y.Wang ,  S.Xu ,  B. J.Groendyke ,  L. H.Sigua ,  I.Tavares ,  C.Zou ,  J. M.Tsai ,  P. M. C.Park ,  H.Yoon ,  F. C.Majewski ,  J. A.Marto ,  J.Qi ,  R. P.Nowak ,  K. A.Donovan ,  M.S\u0142abicki ,  N. S.Gray ,  E. S.Fischer  and  B. L.Ebert ,  bioRxiv ,  2023 , preprint 10.1101\/2023.02.14.528208"},{"key":"D3CS00100H\/cit202\/1","doi-asserted-by":"publisher","DOI":"10.1101\/2023.02.14.528511","volume-title":"bioRxiv","author":"Hsia","year":"2023","unstructured":"O.Hsia ,  M.Hinterndorfer ,  A. D.Cowan ,  K.Iso ,  T.Ishida ,  R.Sundaramoorthy ,  M. A.Nakasone ,  A.Rukavina ,  K.Husnjak ,  M.Wegner ,  A.Correa-S\u00e1ez ,  C.Craigon ,  C.Maniaci ,  A.Testa ,  M.Kaulich ,  I.Dikic ,  G. E.Winter  and  A.Ciulli ,  bioRxiv ,  2023 , preprint 10.1101\/2023.02.14.528511"},{"key":"D3CS00100H\/cit203\/1","doi-asserted-by":"crossref","first-page":"18370","DOI":"10.1021\/jacs.9b06422","volume":"141","author":"Xue","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit204\/1","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1021\/jacs.9b12718","volume":"142","author":"Naro","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit205\/1","doi-asserted-by":"crossref","first-page":"eaay5154","DOI":"10.1126\/sciadv.aay5154","volume":"6","author":"Liu","year":"2020","journal-title":"Sci. Adv."},{"key":"D3CS00100H\/cit206\/1","doi-asserted-by":"crossref","first-page":"113608","DOI":"10.1016\/j.ejmech.2021.113608","volume":"222","author":"Li","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"D3CS00100H\/cit207\/1","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1021\/acscentsci.9b00713","volume":"5","author":"Pfaff","year":"2019","journal-title":"ACS Cent. Sci."},{"key":"D3CS00100H\/cit208\/1","doi-asserted-by":"crossref","first-page":"eaay5064","DOI":"10.1126\/sciadv.aay5064","volume":"6","author":"Reynders","year":"2020","journal-title":"Sci. Adv."},{"key":"D3CS00100H\/cit209\/1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1021\/jacs.2c10177","volume":"145","author":"Yang","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit210\/1","doi-asserted-by":"crossref","first-page":"7380","DOI":"10.1021\/jacs.1c00451","volume":"143","author":"Liu","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"D3CS00100H\/cit211\/1","doi-asserted-by":"crossref","first-page":"23299","DOI":"10.1002\/anie.202107347","volume":"60","author":"He","year":"2021","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3CS00100H\/cit212\/1","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/nchembio.2209","volume":"12","author":"Tanaka","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit213\/1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1038\/s41589-021-00878-4","volume":"17","author":"Imaide","year":"2021","journal-title":"Nat. Chem. Biol."},{"key":"D3CS00100H\/cit214\/1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1021\/acs.bioconjchem.1c00490","volume":"33","author":"Huang","year":"2022","journal-title":"Bioconjugate Chem."},{"key":"D3CS00100H\/cit215\/1","doi-asserted-by":"crossref","first-page":"3886","DOI":"10.1039\/D2CS00141A","volume":"51","author":"Dragovich","year":"2022","journal-title":"Chem. Soc. Rev."},{"key":"D3CS00100H\/cit216\/1","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/s42256-022-00527-y","volume":"4","author":"Zheng","year":"2022","journal-title":"Nat. Mach. Intell."},{"key":"D3CS00100H\/cit217\/1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/s41573-021-00371-6","volume":"21","author":"B\u00e9k\u00e9s","year":"2022","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D3CS00100H\/cit218\/1","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1158\/1535-7163.MCT-18-1129","volume":"18","author":"Zhang","year":"2019","journal-title":"Mol. Cancer Ther."},{"key":"D3CS00100H\/cit219\/1","doi-asserted-by":"crossref","first-page":"108532","DOI":"10.1016\/j.celrep.2020.108532","volume":"34","author":"Shirasaki","year":"2021","journal-title":"Cell Rep."},{"key":"D3CS00100H\/cit220\/1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/s41589-022-01177-2","volume":"19","author":"Hanzl","year":"2023","journal-title":"Nat. Chem. Biol."}],"container-title":["Chemical Society Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/CS\/D3CS00100H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:12:59Z","timestamp":1782969179000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cs\/article\/52\/13\/4313-4342\/803784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":219,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2023,7,3]]}},"URL":"https:\/\/doi.org\/10.1039\/d3cs00100h","relation":{},"ISSN":["0306-0012","1460-4744"],"issn-type":[{"value":"0306-0012","type":"print"},{"value":"1460-4744","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}