{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:53:47Z","timestamp":1787226827077,"version":"build-2736575974"},"reference-count":30,"publisher":"Royal Society of Chemistry (RSC)","issue":"7","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"am","delay-in-days":381,"URL":"http:\/\/rsc.li\/journals-terms-of-use#chorus"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-1625737"],"award-info":[{"award-number":["CHE-1625737"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Dalton Trans."],"abstract":"<jats:p>\n                    Don't waste good iron for nails (or good men for soldiers) but save it for treating cancer! The lipophilic Fe(\n                    <jats:sc>iii<\/jats:sc>\n                    ) chelator chlorquinaldol has the remarkable ability to transport iron across the cell membrane afford potent broad-spectrum\n                    <jats:italic>in vitro<\/jats:italic>\n                    anticancer activity against a panel of cancer cell lines.\n                  <\/jats:p>","DOI":"10.1039\/d3dt02517a","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T12:04:07Z","timestamp":1705406647000},"page":"3206-3214","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Transferrin-inspired iron delivery across the cell membrane using [(L\n                    <sub>2<\/sub>\n                    Fe)\n                    <sub>2<\/sub>\n                    (\u03bc-O)] (L = chlorquinaldol) to harness anticancer activity of ferroptosis"],"prefix":"10.1039","volume":"53","author":[{"given":"Nalin","family":"Abeydeera","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, Kent State University, Kent, OH 44240, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"Mudarmah","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Kent State University, Kent, OH 44240, USA"},{"name":"On leave from Department of Chemistry, Jazan University, Jazan, 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bishnu D.","family":"Pant","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Kent State University, Kent, OH 44240, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette A.","family":"Krause","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221-0172, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4605-1121","authenticated-orcid":false,"given":"Yao-Rong","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Kent State University, Kent, OH 44240, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1298-8226","authenticated-orcid":false,"given":"Songping D.","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Kent State University, Kent, OH 44240, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"29","key":"D3DT02517A\/cit1\/1","doi-asserted-by":"crossref","first-page":"5705","DOI":"10.1021\/bi300752r","volume":"51","author":"Pantopoulos","year":"2012","journal-title":"Biochemistry"},{"issue":"5","key":"D3DT02517A\/cit2\/1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0092-8674(02)01164-9","volume":"111","author":"Kaplan","year":"2002","journal-title":"Cell"},{"issue":"1","key":"D3DT02517A\/cit3\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nchembio.1416","volume":"10","author":"Dixon","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"D3DT02517A\/cit4\/1","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0378-4274(95)03532-X","volume":"82","author":"Winterbourn","year":"1995","journal-title":"Toxicol. Lett."},{"issue":"9","key":"D3DT02517A\/cit5\/1","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.3390\/ijms22094642","volume":"22","author":"Juan","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"D3DT02517A\/cit6\/1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41419-020-2298-2","volume":"11","author":"Li","year":"2020","journal-title":"Cell Death Dis."},{"issue":"3","key":"D3DT02517A\/cit7\/1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0092-8674(04)00343-5","volume":"117","author":"Hentze","year":"2004","journal-title":"Cell"},{"issue":"7","key":"D3DT02517A\/cit8\/1","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.bbamcr.2006.03.014","volume":"1763","author":"Ganz","year":"2006","journal-title":"Biochim. Biophys. Acta, Mol. Cell Res."},{"issue":"22","key":"D3DT02517A\/cit9\/1","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1021\/ja00905a001","volume":"85","author":"Pearson","year":"1963","journal-title":"J. Am. Chem. Soc."},{"issue":"8","key":"D3DT02517A\/cit10\/1","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1021\/cr00098a011","volume":"89","author":"Hancock","year":"1989","journal-title":"Chem. Rev."},{"issue":"6","key":"D3DT02517A\/cit11\/1","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1089\/ars.2007.1893","volume":"10","author":"Mackenzie","year":"2008","journal-title":"Antioxid. Redox Signaling"},{"issue":"5509","key":"D3DT02517A\/cit12\/1","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1126\/science.1057206","volume":"291","author":"McKie","year":"2001","journal-title":"Science"},{"issue":"3","key":"D3DT02517A\/cit13\/1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.bbagen.2011.06.003","volume":"1820","author":"Steere","year":"2012","journal-title":"Biochim. Biophys. Acta, Gen. Subj."},{"issue":"3","key":"D3DT02517A\/cit14\/1","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/BF00390468","volume":"108","author":"K\u00f6pf-Maier","year":"1984","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"33","key":"D3DT02517A\/cit15\/1","doi-asserted-by":"crossref","first-page":"11451","DOI":"10.1039\/D0DT02135K","volume":"49","author":"Bouch\u00e9","year":"2020","journal-title":"Dalton Trans."},{"issue":"2","key":"D3DT02517A\/cit16\/1","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1039\/C5NJ01449B","volume":"40","author":"Wani","year":"2016","journal-title":"New J. Chem."},{"issue":"15","key":"D3DT02517A\/cit17\/1","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.2174\/1568026043387449","volume":"4","author":"Jakupec","year":"2004","journal-title":"Curr. Top. Med. Chem."},{"issue":"3","key":"D3DT02517A\/cit18\/1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1039\/b902861g","volume":"1","author":"Timerbaev","year":"2009","journal-title":"Metallomics"},{"issue":"10","key":"D3DT02517A\/cit19\/1","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.4155\/fmc.12.69","volume":"4","author":"Chitambar","year":"2012","journal-title":"Future Med. Chem."},{"key":"D3DT02517A\/cit20\/1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1021\/acs.jmedchem.2c01684","volume":"66","author":"Yang","year":"2023","journal-title":"J. Med. Chem."},{"key":"D3DT02517A\/cit21\/1","doi-asserted-by":"crossref","first-page":"7268","DOI":"10.1021\/acs.jmedchem.2c01904","volume":"66","author":"Man","year":"2023","journal-title":"J. Med. Chem."},{"key":"D3DT02517A\/cit22\/1","doi-asserted-by":"crossref","first-page":"7497","DOI":"10.1021\/acs.jmedchem.6b00509","volume":"59","author":"Qi","year":"2016","journal-title":"J. Med. Chem."},{"issue":"13","key":"D3DT02517A\/cit23\/1","doi-asserted-by":"crossref","first-page":"4917","DOI":"10.3390\/molecules28134917","volume":"28","author":"Abeydeera","year":"2023","journal-title":"Molecules"},{"key":"D3DT02517A\/cit24\/1","author":"Held","unstructured":"P.Held"},{"issue":"6","key":"D3DT02517A\/cit25\/1","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1177\/1091581816659661","volume":"35","author":"Al-Anbaky","year":"2016","journal-title":"Int. J. Toxicol."},{"issue":"1","key":"D3DT02517A\/cit26\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-4598-10-142","volume":"10","author":"Sun","year":"2011","journal-title":"Mol. Cancer"},{"issue":"8","key":"D3DT02517A\/cit27\/1","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1089\/ars.2007.1957","volume":"10","author":"Trachootham","year":"2008","journal-title":"Antioxid. Redox Signaling"},{"issue":"5","key":"D3DT02517A\/cit28\/1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3109\/10715761003667554","volume":"44","author":"Liou","year":"2010","journal-title":"Free Radical Res."},{"issue":"19","key":"D3DT02517A\/cit28\/2","doi-asserted-by":"crossref","first-page":"8788","DOI":"10.1073\/pnas.1003428107","volume":"107","author":"Weinberg","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3DT02517A\/cit29\/1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1039\/D1BM01743H","volume":"10","author":"Abeydeera","year":"2022","journal-title":"Biomater. Sci."}],"container-title":["Dalton Transactions"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/DT\/D3DT02517A","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/DT\/D3DT02517A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:39:05Z","timestamp":1782884345000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/dt\/article\/53\/7\/3206-3214\/806151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,2,13]]}},"URL":"https:\/\/doi.org\/10.1039\/d3dt02517a","relation":{},"ISSN":["1477-9226","1477-9234"],"issn-type":[{"value":"1477-9226","type":"print"},{"value":"1477-9234","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}