{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:03:48Z","timestamp":1790870628786,"version":"4.1.0"},"reference-count":50,"publisher":"Royal Society of Chemistry (RSC)","issue":"8","license":[{"start":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:00:00Z","timestamp":1711324800000},"content-version":"vor","delay-in-days":84,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["FWF-KLI 858"],"award-info":[{"award-number":["FWF-KLI 858"]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    In this randomized placebo-controlled crossover study, we evaluated whether previously reported cardiovascular benefits of plant-derived inorganic nitrate\n                    <jats:italic>via<\/jats:italic>\n                    NO translate into improved vascular function and blood pressure-lowering in middle-aged and older men and women with treated hypertension.\n                  <\/jats:p>","DOI":"10.1039\/d3fo03749e","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T07:43:07Z","timestamp":1711352587000},"page":"4065-4078","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension"],"prefix":"10.1039","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2648-4643","authenticated-orcid":false,"given":"Rebeka","family":"Fejes","sequence":"first","affiliation":[{"name":"Department of Nutritional Sciences, Research Platform Active Ageing, University of Vienna, Vienna, Austria"},{"name":"Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences, University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4950-9380","authenticated-orcid":false,"given":"Martin","family":"Lutnik","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Weisshaar","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4071-9397","authenticated-orcid":false,"given":"Nina","family":"Pilat","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Heinz","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, Research Platform Active Ageing, University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"St\u00fcger","sequence":"additional","affiliation":[{"name":"Division Integrative Risk Assessment, Data and Statistics, Austrian Agency for Health and Food Safety, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Peake","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences, Queensland University of Technology, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Woodman","sequence":"additional","affiliation":[{"name":"Flinders Centre for Epidemiology and Biostatistics, Flinders University, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1596-4913","authenticated-orcid":false,"given":"Kevin D.","family":"Croft","sequence":"additional","affiliation":[{"name":"Medical School, University of Western Australia, Royal Perth Hospital Unit, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8509-439X","authenticated-orcid":false,"given":"Catherine P.","family":"Bondonno","sequence":"additional","affiliation":[{"name":"Nutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Royal Perth Hospital Research Foundation, Edith Cowan University, Joondalup, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Hodgson","sequence":"additional","affiliation":[{"name":"Nutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Royal Perth Hospital Research Foundation, Edith Cowan University, Joondalup, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wolzt","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6835-8787","authenticated-orcid":false,"given":"Oliver","family":"Neubauer","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, Research Platform Active Ageing, University of Vienna, Vienna, Austria"},{"name":"Centre for Health Sciences and Medicine, University for Continuing Education Krems, Krems, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3FO03749E\/cit1\/1","doi-asserted-by":"crossref","first-page":"e153","DOI":"10.1161\/CIR.0000000000001052","volume":"145","author":"Tsao","year":"2022","journal-title":"Circulation"},{"key":"D3FO03749E\/cit2\/1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/eurheartj\/ehz859","volume":"41","author":"Timmis","year":"2020","journal-title":"Eur. Heart J."},{"key":"D3FO03749E\/cit3\/1","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1152\/japplphysiol.00521.2018","volume":"125","author":"Rossman","year":"2018","journal-title":"J. Appl. Physiol."},{"key":"D3FO03749E\/cit4\/1","first-page":"e426","volume":"138","author":"Whelton","year":"2018","journal-title":"Circulation"},{"key":"D3FO03749E\/cit5\/1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1042\/CS20100476","volume":"120","author":"Seals","year":"2011","journal-title":"Clin. Sci."},{"key":"D3FO03749E\/cit6\/1","doi-asserted-by":"crossref","first-page":"e472","DOI":"10.1161\/CIR.0000000000001031","volume":"144","author":"Lichtenstein","year":"2021","journal-title":"Circulation"},{"key":"D3FO03749E\/cit7\/1","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1093\/ije\/dyw319","volume":"46","author":"Aune","year":"2017","journal-title":"Int. J. Epidemiol."},{"key":"D3FO03749E\/cit8\/1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/ajcn\/nqx046","volume":"107","author":"Blekkenhorst","year":"2018","journal-title":"Am. J. Clin. Nutr."},{"issue":"8","key":"D3FO03749E\/cit9\/1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/nutrit\/nuz025","volume":"77","author":"Raubenheimer","year":"2019","journal-title":"Nutr. Rev."},{"key":"D3FO03749E\/cit10\/1","first-page":"H195","volume":"314","author":"Woessner","year":"2018","journal-title":"Am. J. Physiol.: Heart Circ. Physiol."},{"key":"D3FO03749E\/cit11\/1","doi-asserted-by":"publisher","first-page":"e13080","DOI":"10.1111\/apha.13080","author":"Carlstrom","year":"2018","journal-title":"Acta Physiol."},{"key":"D3FO03749E\/cit12\/1","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrd4623","volume":"14","author":"Lundberg","year":"2015","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D3FO03749E\/cit13\/1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1152\/physiol.00059.2013","volume":"29","author":"Seals","year":"2014","journal-title":"Physiology"},{"key":"D3FO03749E\/cit14\/1","first-page":"H991","volume":"320","author":"Casey","year":"2021","journal-title":"Am. J. Physiol.: Heart Circ. Physiol."},{"key":"D3FO03749E\/cit15\/1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3945\/ajcn.115.116244","volume":"103","author":"Velmurugan","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"D3FO03749E\/cit16\/1","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1161\/HYPERTENSIONAHA.114.04675","volume":"65","author":"Kapil","year":"2015","journal-title":"Hypertension"},{"key":"D3FO03749E\/cit17\/1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.freeradbiomed.2011.09.028","volume":"52","author":"Bondonno","year":"2012","journal-title":"Free Radicals Biol. Med."},{"key":"D3FO03749E\/cit18\/1","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1152\/japplphysiol.00371.2019","volume":"127","author":"Broxterman","year":"2019","journal-title":"J. Appl. Physiol."},{"issue":"11","key":"D3FO03749E\/cit19\/1","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.3390\/nu9111270","volume":"9","author":"Raubenheimer","year":"2017","journal-title":"Nutrients"},{"key":"D3FO03749E\/cit20\/1","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1093\/ajcn\/nqy061","volume":"107","author":"Blekkenhorst","year":"2018","journal-title":"Am. J. Clin. Nutr."},{"issue":"4","key":"D3FO03749E\/cit21\/1","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/ajcn\/nqaa024","volume":"111","author":"Sundqvist","year":"2020","journal-title":"Am. J. Clin. Nutr."},{"key":"D3FO03749E\/cit22\/1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.freeradbiomed.2013.01.024","volume":"60","author":"Gilchrist","year":"2013","journal-title":"Free Radicals Biol. Med."},{"key":"D3FO03749E\/cit23\/1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/nutrit\/nuy005","volume":"76","author":"Jackson","year":"2018","journal-title":"Nutr. Rev."},{"key":"D3FO03749E\/cit24\/1","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1093\/eurheartj\/ehaa857","volume":"42","author":"Masi","year":"2021","journal-title":"Eur. Heart J."},{"key":"D3FO03749E\/cit25\/1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1161\/CIRCRESAHA.115.305364","volume":"118","author":"Gutterman","year":"2016","journal-title":"Circ. Res."},{"key":"D3FO03749E\/cit26\/1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1046\/j.0306-5251.2001.01495.x","volume":"52","author":"Wilkinson","year":"2001","journal-title":"Br. J. Clin. Pharmacol."},{"key":"D3FO03749E\/cit27\/1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1365-2125.1998.00656.x","volume":"45","author":"Petrie","year":"1998","journal-title":"Br. J. Clin. Pharmacol."},{"key":"D3FO03749E\/cit28\/1","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1111\/bcp.13378","volume":"83","author":"Weisshaar","year":"2017","journal-title":"Br. J. Clin. Pharmacol."},{"key":"D3FO03749E\/cit29\/1","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1161\/CIRCULATIONAHA.110.984047","volume":"123","author":"Lind","year":"2011","journal-title":"Circulation"},{"key":"D3FO03749E\/cit30\/1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1161\/01.CIR.0000048892.83521.58","volume":"107","author":"Lakatta","year":"2003","journal-title":"Circulation"},{"issue":"2","key":"D3FO03749E\/cit31\/1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1026\/0943-8149\/a000137","volume":"23","author":"Fuchs","year":"2015","journal-title":"Zeitschrift f\u00fcr Gesundheitspsychologie"},{"key":"D3FO03749E\/cit32\/1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1475-2891-9-36","volume":"9","author":"Haftenberger","year":"2010","journal-title":"Nutr. J."},{"key":"D3FO03749E\/cit33\/1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1249\/MSS.0000000000002470","volume":"53","author":"Jones","year":"2021","journal-title":"Med. Sci. Sports Exercise"},{"key":"D3FO03749E\/cit34\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2012.12.002","volume":"56","author":"Yang","year":"2013","journal-title":"Free Radicals Biol. Med."},{"key":"D3FO03749E\/cit35\/1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.tifs.2023.03.014","volume":"135","author":"Bondonno","year":"2023","journal-title":"Trends Food Sci. Technol."},{"key":"D3FO03749E\/cit36\/1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1152\/japplphysiol.00372.2013","volume":"115","author":"Wylie","year":"2013","journal-title":"J. Appl. Physiol."},{"key":"D3FO03749E\/cit37\/1","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1161\/HYPERTENSIONAHA.107.103523","volume":"51","author":"Webb","year":"2008","journal-title":"Hypertension"},{"key":"D3FO03749E\/cit38\/1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/joim.12441","volume":"279","author":"Omar","year":"2016","journal-title":"J. Intern. Med."},{"key":"D3FO03749E\/cit39\/1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.niox.2012.01.004","volume":"26","author":"Bahra","year":"2012","journal-title":"Nitric Oxide"},{"key":"D3FO03749E\/cit40\/1","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1152\/japplphysiol.00292.2019","volume":"127","author":"Shepherd","year":"2019","journal-title":"J. Appl. Physiol."},{"key":"D3FO03749E\/cit41\/1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00394-015-0872-7","volume":"55","author":"Lara","year":"2016","journal-title":"Eur. J. Nutr."},{"key":"D3FO03749E\/cit42\/1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1093\/cvr\/cvq366","volume":"89","author":"Carlstrom","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"D3FO03749E\/cit43\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S000711452100324X","author":"Parmenter","year":"2021","journal-title":"Br. J. Nutr."},{"key":"D3FO03749E\/cit44\/1","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/j.nutres.2014.09.007","volume":"34","author":"Jajja","year":"2014","journal-title":"Nutr. Res."},{"key":"D3FO03749E\/cit45\/1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/ars.2013.5481","volume":"23","author":"Carlstrom","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"D3FO03749E\/cit46\/1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.freeradbiomed.2016.08.009","volume":"99","author":"Bakker","year":"2016","journal-title":"Free Radicals Biol. Med."},{"key":"D3FO03749E\/cit47\/1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.niox.2021.11.001","volume":"118","author":"Baranauskas","year":"2022","journal-title":"Nitric Oxide"},{"key":"D3FO03749E\/cit48\/1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1152\/japplphysiol.00220.2023","volume":"135","author":"Ortiz de Zevallos","year":"2023","journal-title":"J. Appl. Physiol."},{"key":"D3FO03749E\/cit49\/1","doi-asserted-by":"crossref","first-page":"133411","DOI":"10.1016\/j.foodchem.2022.133411","volume":"394","author":"Zhong","year":"2022","journal-title":"Food Chem."},{"key":"D3FO03749E\/cit50\/1","doi-asserted-by":"crossref","first-page":"1600982","DOI":"10.1002\/mnfr.201600982","volume":"61","author":"Blekkenhorst","year":"2017","journal-title":"Mol. Nutr. Food Res."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/FO\/D3FO03749E","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:36:04Z","timestamp":1782966964000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/15\/8\/4065-4078\/809631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":50,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,4,22]]}},"URL":"https:\/\/doi.org\/10.1039\/d3fo03749e","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}