{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:57:59Z","timestamp":1782943079404,"version":"3.54.5"},"reference-count":60,"publisher":"Royal Society of Chemistry (RSC)","issue":"3","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    Silicon-enriched meat\n                    <jats:italic>vs<\/jats:italic>\n                    . control meat improves dyslipaemia, oxidation, and HOMA-beta levels in rat, leading to a less advanced late-stage T2DM by improving the increase in faecal fat excretion and reducing plasma triglyceride and VLDL presence.\n                  <\/jats:p>","DOI":"10.1039\/d3fo04103d","type":"journal-article","created":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T02:08:43Z","timestamp":1704074923000},"page":"1513-1526","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Silicon-enriched meat positively improves plasma lipidaemia and lipoproteinaemia, LDLr, and insulin capability and the signalling pathway induced by an atherogenic diet in late-stage type 2 diabetes mellitus rats"],"prefix":"10.1039","volume":"15","author":[{"given":"Marina","family":"Hern\u00e1ndez-Mart\u00edn","sequence":"first","affiliation":[{"name":"Departmental Section of Physiology, Pharmacy School, Complutense University of Madrid, Plaza Ram\u00f3n y Cajal s\/n, 28040-Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"Macho-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Nutrition and Food Science Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alba","family":"Garcimart\u00edn","sequence":"additional","affiliation":[{"name":"Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0615-9149","authenticated-orcid":false,"given":"M\u00aa Elvira","family":"L\u00f3pez-Oliva","sequence":"additional","affiliation":[{"name":"Departmental Section of Physiology, Pharmacy School, Complutense University of Madrid, Plaza Ram\u00f3n y Cajal s\/n, 28040-Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7040-2126","authenticated-orcid":false,"given":"Ar\u00e1nzazu","family":"Bocanegra","sequence":"additional","affiliation":[{"name":"Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6864-5719","authenticated-orcid":false,"given":"Roc\u00edo","family":"Redondo-Castillejo","sequence":"additional","affiliation":[{"name":"Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Bastida","sequence":"additional","affiliation":[{"name":"Nutrition and Food Science Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3796-639X","authenticated-orcid":false,"given":"Juana","family":"Bened\u00ed","sequence":"additional","affiliation":[{"name":"Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"S\u00e1nchez-Muniz","sequence":"additional","affiliation":[{"name":"Nutrition and Food Science Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3FO04103D\/cit1\/1","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ecl.2006.06.002","volume":"35","author":"Chahil","year":"2006","journal-title":"Endocrinol. Metab. Clin. North Am."},{"key":"D3FO04103D\/cit2\/1","doi-asserted-by":"crossref","first-page":"108653","DOI":"10.1016\/j.diabres.2021.108653","volume":"172","author":"Vaquero","year":"2021","journal-title":"Diabetes Res. Clin. Pract."},{"key":"D3FO04103D\/cit3\/1","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.3390\/ijms21176275","volume":"21","author":"Galicia-Garcia","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D3FO04103D\/cit4\/1","doi-asserted-by":"crossref","first-page":"771","DOI":"10.5551\/jat.RV17023","volume":"25","author":"Hirano","year":"2018","journal-title":"J. Atheroscler. Thromb."},{"key":"D3FO04103D\/cit5\/1","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1210\/jcem.86.3.7304","volume":"86","author":"Goldberg","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"D3FO04103D\/cit6\/1","author":"International Diabetes Federation","unstructured":"International Diabetes Federation , Diabetes Complications,  https:\/\/idf.org\/about-diabetes\/diabetes-complications\/"},{"key":"D3FO04103D\/cit7\/1","doi-asserted-by":"crossref","first-page":"612","DOI":"10.3390\/biomedicines9060612","volume":"9","author":"Gracia-Rubio","year":"2021","journal-title":"Biomedicines"},{"key":"D3FO04103D\/cit8\/1","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.3390\/nu10121830","volume":"26","author":"Santos-L\u00f3pez","year":"2018","journal-title":"Nutrients"},{"key":"D3FO04103D\/cit9\/1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","volume":"340","author":"Ross","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"D3FO04103D\/cit10\/1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1093\/jn\/128.2.444S","volume":"128","author":"Dietschy","year":"1998","journal-title":"J. Nutr."},{"key":"D3FO04103D\/cit11\/1","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1161\/ATVBAHA.111.241463","volume":"32","author":"Sparks","year":"2012","journal-title":"Arterioscler., Thromb., Vasc. Biol."},{"key":"D3FO04103D\/cit12\/1","doi-asserted-by":"crossref","first-page":"6903","DOI":"10.3390\/ijms14046903","volume":"14","author":"de la Iglesia","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"D3FO04103D\/cit13\/1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0025-7753(03)74011-1","volume":"121","author":"Canales","year":"2003","journal-title":"Med. Clin."},{"key":"D3FO04103D\/cit14\/1","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s13105-016-0505-5","volume":"72","author":"Celada","year":"2016","journal-title":"J. Physiol. Biochem."},{"key":"D3FO04103D\/cit15\/1","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1017\/S0007114510005015","volume":"105","author":"V\u00e1zquez-Velasco","year":"2011","journal-title":"Br. J. Nutr."},{"key":"D3FO04103D\/cit16\/1","doi-asserted-by":"crossref","first-page":"638","DOI":"10.3390\/antiox9070638","volume":"9","author":"Macho-Gonz\u00e1lez","year":"2020","journal-title":"Antioxidants"},{"key":"D3FO04103D\/cit17\/1","doi-asserted-by":"crossref","first-page":"756","DOI":"10.7326\/M19-1621","volume":"171","author":"Johnston","year":"2019","journal-title":"Ann. Intern. Med."},{"key":"D3FO04103D\/cit18\/1","doi-asserted-by":"crossref","first-page":"897","DOI":"10.3390\/nu6020897","volume":"6","author":"Barnard","year":"2014","journal-title":"Nutrients"},{"key":"D3FO04103D\/cit19\/1","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.meatsci.2013.03.030","volume":"95","author":"Olmedilla-Alonso","year":"2013","journal-title":"Meat Sci."},{"key":"D3FO04103D\/cit20\/1","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.foodchem.2010.05.104","volume":"123","author":"Jim\u00e9nez-Colmenero","year":"2010","journal-title":"Food Chem."},{"key":"D3FO04103D\/cit21\/1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s00394-013-0502-1","volume":"53","author":"Delgado-Pando","year":"2014","journal-title":"Eur. J. Nutr."},{"key":"D3FO04103D\/cit22\/1","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1093\/advances\/nmaa182","volume":"12","author":"Macho-Gonz\u00e1lez","year":"2021","journal-title":"Adv. Nutr."},{"key":"D3FO04103D\/cit23\/1","first-page":"603","volume":"88","author":"S\u00e1nchez-Muniz","year":"2022","journal-title":"An. R. Acad. Farm."},{"key":"D3FO04103D\/cit24\/1","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.3390\/foods11081107","volume":"11","author":"Pe\u00f1alver","year":"2022","journal-title":"Foods"},{"key":"D3FO04103D\/cit25\/1","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.3945\/jn.115.213934","volume":"145","author":"Garcimart\u00edn","year":"2015","journal-title":"J. Nutr."},{"key":"D3FO04103D\/cit26\/1","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.3390\/nu11071558","volume":"11","author":"S\u00e1nchez-Muniz","year":"2019","journal-title":"Nutrients"},{"key":"D3FO04103D\/cit27\/1","doi-asserted-by":"crossref","first-page":"917","DOI":"10.3233\/JAD-160972","volume":"56","author":"Gonz\u00e1lez-Mu\u00f1oz","year":"2017","journal-title":"J. Alzheimer's Dis."},{"key":"D3FO04103D\/cit28\/1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/978-94-007-7500-8_14","volume":"13","author":"Martin","year":"2013","journal-title":"Met. Ions Life Sci."},{"key":"D3FO04103D\/cit29\/1","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.fct.2018.06.004","volume":"118","author":"Merino","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"D3FO04103D\/cit30\/1","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/jn\/124.6.853","volume":"124","author":"Peluso","year":"1994","journal-title":"J. Nutr."},{"key":"D3FO04103D\/cit31\/1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jff.2016.12.040","volume":"29","author":"Garcimart\u00edn","year":"2017","journal-title":"J. Funct. Foods"},{"key":"D3FO04103D\/cit32\/1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0306-9877(97)90224-3","volume":"49","author":"McCarty","year":"1997","journal-title":"Med. Hypotheses"},{"key":"D3FO04103D\/cit33\/1","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.3945\/jn.116.243204","volume":"147","author":"Garcimart\u00edn","year":"2017","journal-title":"J. Nutr."},{"key":"D3FO04103D\/cit34\/1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/mnfr.202200104","volume":"66","author":"Hern\u00e1ndez-Mart\u00edn","year":"2022","journal-title":"Mol. Nutr. Food Res."},{"key":"D3FO04103D\/cit35\/1","doi-asserted-by":"crossref","first-page":"108461","DOI":"10.1016\/j.jnutbio.2020.108461","volume":"84","author":"Macho-Gonz\u00e1lez","year":"2020","journal-title":"J. Nutr. Biochem."},{"key":"D3FO04103D\/cit36\/1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0003-2697(81)90243-8","volume":"111","author":"Terpstra","year":"1981","journal-title":"Anal. Biochem."},{"key":"D3FO04103D\/cit37\/1","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1017\/S000711451100198X","volume":"106","author":"Olivero-David","year":"2011","journal-title":"Br. J. Nutr."},{"key":"D3FO04103D\/cit38\/1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"D3FO04103D\/cit39\/1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0003-2697(78)90342-1","volume":"86","author":"Mihara","year":"1978","journal-title":"Anal. Biochem."},{"key":"D3FO04103D\/cit40\/1","doi-asserted-by":"crossref","first-page":"103600","DOI":"10.1016\/j.jff.2019.103600","volume":"64","author":"Macho-Gonz\u00e1lez","year":"2020","journal-title":"J. Funct. Foods"},{"key":"D3FO04103D\/cit41\/1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s13105-016-0525-1","volume":"73","author":"Ruperto","year":"2017","journal-title":"J. Physiol. Biochem."},{"key":"D3FO04103D\/cit42\/1","doi-asserted-by":"crossref","first-page":"110124","DOI":"10.1016\/j.foodres.2021.110124","volume":"141","author":"Macho-Gonz\u00e1lez","year":"2021","journal-title":"Food Res. Int."},{"key":"D3FO04103D\/cit43\/1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/ejlt.200700280","volume":"110","author":"S\u00e1nchez-Muniz","year":"2008","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"D3FO04103D\/cit44\/1","first-page":"328","volume":"68","author":"Chiang","year":"1998","journal-title":"Int. J. Vitam. Nutr. Res."},{"key":"D3FO04103D\/cit45\/1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1177\/1082013203038860","volume":"9","author":"Bastida","year":"2003","journal-title":"Food Sci. Technol. Int."},{"key":"D3FO04103D\/cit46\/1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3390\/nu11020332","volume":"1","author":"Macho-Gonz\u00e1lez","year":"2019","journal-title":"Nutrients"},{"key":"D3FO04103D\/cit47\/1","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0140-6736(77)91945-6","volume":"1","author":"Schwarz","year":"1977","journal-title":"Lancet"},{"key":"D3FO04103D\/cit48\/1","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.pharep.2016.07.010","volume":"68","author":"Sah","year":"2016","journal-title":"Pharmacol. Rep."},{"key":"D3FO04103D\/cit49\/1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/jdi.12235","volume":"5","author":"Skovs\u00f8","year":"2014","journal-title":"J. Diabetes Invest."},{"key":"D3FO04103D\/cit50\/1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.tem.2013.04.001","volume":"24","author":"Haas","year":"2013","journal-title":"Trends Endocrinol. Metab."},{"key":"D3FO04103D\/cit51\/1","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/j.foodchem.2011.06.019","volume":"129","author":"Schultz Moreira","year":"2011","journal-title":"Food Chem."},{"key":"D3FO04103D\/cit52\/1","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1210\/jc.2011-3213","volume":"97","author":"Berglund","year":"2012","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"D3FO04103D\/cit53\/1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2337\/dc09-S301","volume":"32","author":"Fonseca","year":"2009","journal-title":"Diabetes Care"},{"key":"D3FO04103D\/cit54\/1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1146\/annurev-physiol-021317-121550","volume":"80","author":"Shen","year":"2018","journal-title":"Annu. Rev. Physiol."},{"key":"D3FO04103D\/cit55\/1","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s13105-015-0441-9","volume":"71","author":"Gonz\u00e1lez-Torres","year":"2015","journal-title":"J. Physiol. Biochem."},{"key":"D3FO04103D\/cit56\/1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s11130-010-0179-z","volume":"65","author":"Schultz Moreira","year":"2010","journal-title":"Plant Foods Hum. Nutr."},{"key":"D3FO04103D\/cit57\/1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/0005-2760(72)90034-3","volume":"260","author":"Bilheimer","year":"1972","journal-title":"Biochim. Biophys. Acta"},{"key":"D3FO04103D\/cit58\/1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.tem.2011.04.007","volume":"22","author":"Choi","year":"2011","journal-title":"Trends Endocrinol. Metab."},{"key":"D3FO04103D\/cit59\/1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/978-3-642-71702-4_7","volume-title":"Drugs Affecting Lipid Metabolism","author":"Steinberg","year":"1987","unstructured":"D.Steinberg ,  Drugs Affecting Lipid Metabolism ,  Springer ,  Berlin, Heidelberg ,  1987 , pp.  42\u201347"},{"key":"D3FO04103D\/cit60\/1","doi-asserted-by":"crossref","first-page":"5435","DOI":"10.1073\/pnas.80.17.5435","volume":"80","author":"Glass","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/FO\/D3FO04103D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:25:33Z","timestamp":1782941133000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/15\/3\/1513-1526\/809681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,2,5]]}},"URL":"https:\/\/doi.org\/10.1039\/d3fo04103d","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}