{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:21:30Z","timestamp":1791361290251,"version":"4.3.1"},"reference-count":58,"publisher":"Royal Society of Chemistry (RSC)","issue":"7","license":[{"start":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T00:00:00Z","timestamp":1709510400000},"content-version":"vor","delay-in-days":63,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2022ZFJH003"],"award-info":[{"award-number":["2022ZFJH003"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    <jats:italic>Pediococcus pentosaceus<\/jats:italic>\n                    Li05 (Li05) mainly improves IBS-D by reducing 5-HT3B expression, improving intestinal mucosal inflammation, intestinal microbiota, and metabolites, and modulating intestinal microbiota and metabolite production.\n                  <\/jats:p>","DOI":"10.1039\/d3fo04904c","type":"journal-article","created":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T08:01:13Z","timestamp":1709539273000},"page":"3692-3708","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Protective effect of\n                    <i>Pediococcus pentosaceus<\/i>\n                    Li05 on diarrhea-predominant irritable bowel syndrome in rats"],"prefix":"10.1039","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1504-1812","authenticated-orcid":false,"given":"Youhe","family":"Wu","sequence":"first","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengjie","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4114-9402","authenticated-orcid":false,"given":"Longxian","family":"Lv","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiman","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lvwan","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6945-0593","authenticated-orcid":false,"given":"Lanjuan","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3FO04904C\/cit1\/1","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1001\/jama.2015.0954","volume":"313","author":"Chey","year":"2015","journal-title":"J. Am. Med. Assoc."},{"key":"D3FO04904C\/cit2\/1","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/S0140-6736(20)31548-8","volume":"396","author":"Ford","year":"2020","journal-title":"Lancet"},{"key":"D3FO04904C\/cit3\/1","doi-asserted-by":"crossref","first-page":"154350","DOI":"10.1016\/j.phymed.2022.154350","volume":"107","author":"Zhang","year":"2022","journal-title":"Phytomedicine"},{"key":"D3FO04904C\/cit4\/1","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.3390\/jcm12051725","volume":"12","author":"Rodrigues","year":"2023","journal-title":"J. Clin. Med."},{"key":"D3FO04904C\/cit5\/1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/MED.0000000000000523","volume":"27","author":"Canakis","year":"2020","journal-title":"Curr. Opin. Endocrinol., Diabetes Obes."},{"key":"D3FO04904C\/cit6\/1","doi-asserted-by":"crossref","first-page":"746923","DOI":"10.3389\/fphar.2021.746923","volume":"12","author":"Zhen","year":"2021","journal-title":"Front. Pharmacol."},{"key":"D3FO04904C\/cit7\/1","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1080\/00365520802276127","volume":"43","author":"Macsharry","year":"2008","journal-title":"Scand. J. Gastroenterol."},{"key":"D3FO04904C\/cit8\/1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S2468-1253(16)30023-1","volume":"1","author":"Holtmann","year":"2016","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"D3FO04904C\/cit9\/1","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1053\/j.gastro.2003.09.028","volume":"125","author":"Dunlop","year":"2003","journal-title":"Gastroenterology"},{"key":"D3FO04904C\/cit10\/1","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1053\/j.gastro.2022.02.016","volume":"162","author":"Gao","year":"2022","journal-title":"Gastroenterology"},{"key":"D3FO04904C\/cit11\/1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1136\/gut.52.5.663","volume":"52","author":"Houghton","year":"2003","journal-title":"Gut"},{"key":"D3FO04904C\/cit12\/1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1046\/j.1365-2036.2003.01399.x","volume":"17","author":"Simren","year":"2003","journal-title":"Aliment. Pharmacol. Ther."},{"key":"D3FO04904C\/cit13\/1","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.cell.2015.02.047","volume":"161","author":"Yano","year":"2015","journal-title":"Cell"},{"key":"D3FO04904C\/cit14\/1","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1136\/gutjnl-2015-309990","volume":"65","author":"Marchesi","year":"2016","journal-title":"Gut"},{"key":"D3FO04904C\/cit15\/1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.chom.2022.11.006","volume":"31","author":"Zhai","year":"2023","journal-title":"Cell Host Microbe"},{"key":"D3FO04904C\/cit16\/1","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.3389\/fmicb.2018.01600","volume":"9","author":"Zhuang","year":"2018","journal-title":"Front. Microbiol."},{"key":"D3FO04904C\/cit17\/1","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1136\/gutjnl-2011-301501","volume":"61","author":"Jeffery","year":"2012","journal-title":"Gut"},{"key":"D3FO04904C\/cit18\/1","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1038\/ajg.2014.202","volume":"109","author":"Ford","year":"2014","journal-title":"Am. J. Gastroenterol."},{"key":"D3FO04904C\/cit19\/1","doi-asserted-by":"crossref","first-page":"827395","DOI":"10.3389\/fcimb.2022.827395","volume":"12","author":"Wu","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D3FO04904C\/cit20\/1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13099-014-0036-y","volume":"6","author":"Lv","year":"2014","journal-title":"Gut Pathog."},{"key":"D3FO04904C\/cit21\/1","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1111\/1751-7915.13583","volume":"13","author":"Bian","year":"2020","journal-title":"Microb. Biotechnol."},{"key":"D3FO04904C\/cit22\/1","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.3389\/fmicb.2018.02396","volume":"9","author":"Xu","year":"2018","journal-title":"Front. Microbiol."},{"key":"D3FO04904C\/cit23\/1","doi-asserted-by":"crossref","first-page":"6927","DOI":"10.1038\/s41598-017-07091-1","volume":"7","author":"Shi","year":"2017","journal-title":"Sci. Rep."},{"key":"D3FO04904C\/cit24\/1","doi-asserted-by":"crossref","first-page":"112811","DOI":"10.1016\/j.biopha.2022.112811","volume":"149","author":"Wu","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"D3FO04904C\/cit25\/1","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1002\/iub.2270","volume":"72","author":"Fei","year":"2020","journal-title":"IUBMB Life"},{"key":"D3FO04904C\/cit26\/1","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1111\/jgh.15981","volume":"37","author":"Li","year":"2022","journal-title":"J. Gastroenterol. Hepatol."},{"key":"D3FO04904C\/cit27\/1","doi-asserted-by":"crossref","first-page":"5469","DOI":"10.3748\/wjg.v25.i36.5469","volume":"25","author":"Zhao","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"D3FO04904C\/cit28\/1","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1111\/nmo.12675","volume":"27","author":"Moloney","year":"2015","journal-title":"Neurogastroenterol. Motil."},{"key":"D3FO04904C\/cit29\/1","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.2147\/JIR.S331303","volume":"15","author":"Shen","year":"2022","journal-title":"J. Inflammation Res."},{"key":"D3FO04904C\/cit30\/1","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1007\/s10620-008-0244-8","volume":"53","author":"Choi","year":"2008","journal-title":"Dig. Dis Sci."},{"key":"D3FO04904C\/cit31\/1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1053\/j.gastro.2019.06.014","volume":"157","author":"Carrasco-Labra","year":"2019","journal-title":"Gastroenterology"},{"key":"D3FO04904C\/cit32\/1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/ajg.2011.423","volume":"107","author":"Chang","year":"2012","journal-title":"Am. J. Gastroenterol."},{"key":"D3FO04904C\/cit33\/1","doi-asserted-by":"crossref","first-page":"113925","DOI":"10.1016\/j.jep.2021.113925","volume":"272","author":"Xie","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"D3FO04904C\/cit34\/1","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1053\/j.gastro.2007.01.046","volume":"132","author":"Liebregts","year":"2007","journal-title":"Gastroenterology"},{"key":"D3FO04904C\/cit35\/1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.bbi.2014.07.001","volume":"42","author":"Hughes","year":"2014","journal-title":"Brain, Behav., Immun."},{"key":"D3FO04904C\/cit36\/1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/j.gastro.2006.11.002","volume":"132","author":"Gershon","year":"2007","journal-title":"Gastroenterology"},{"key":"D3FO04904C\/cit37\/1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.immuni.2020.10.014","volume":"54","author":"Chen","year":"2021","journal-title":"Immunity"},{"key":"D3FO04904C\/cit38\/1","doi-asserted-by":"crossref","first-page":"S184","DOI":"10.1097\/01.mcg.0000156403.37240.30","volume":"39","author":"Gershon","year":"2005","journal-title":"J. Clin. Gastroenterol."},{"key":"D3FO04904C\/cit39\/1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2165\/00003495-199855020-00002","volume":"55","author":"Gregory","year":"1998","journal-title":"Drugs"},{"key":"D3FO04904C\/cit40\/1","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.3390\/nu13051506","volume":"13","author":"Altomare","year":"2021","journal-title":"Nutrients"},{"key":"D3FO04904C\/cit41\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40168-022-01450-5","volume":"11","author":"Jacobs","year":"2023","journal-title":"Microbiome"},{"key":"D3FO04904C\/cit42\/1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/ajg.2014.427","volume":"110","author":"Rajilic-Stojanovic","year":"2015","journal-title":"Am. J. Gastroenterol."},{"key":"D3FO04904C\/cit43\/1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.chom.2019.03.004","volume":"25","author":"Herp","year":"2019","journal-title":"Cell Host Microbe"},{"key":"D3FO04904C\/cit44\/1","doi-asserted-by":"crossref","first-page":"1788898","DOI":"10.1080\/19490976.2020.1788898","volume":"12","author":"Nagayama","year":"2020","journal-title":"Gut Microbes"},{"key":"D3FO04904C\/cit45\/1","doi-asserted-by":"crossref","first-page":"e0004722","DOI":"10.1128\/spectrum.00047-22","volume":"10","author":"Zhuge","year":"2022","journal-title":"Microbiol. Spectrum"},{"key":"D3FO04904C\/cit46\/1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3390\/metabo11080482","volume":"11","author":"Jo","year":"2021","journal-title":"Metabolites"},{"key":"D3FO04904C\/cit47\/1","doi-asserted-by":"crossref","first-page":"1014881","DOI":"10.3389\/fimmu.2022.1014881","volume":"13","author":"Fu","year":"2022","journal-title":"Front. Immunol."},{"key":"D3FO04904C\/cit48\/1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/s00018-022-04471-3","volume":"79","author":"Huang","year":"2022","journal-title":"Cell. Mol. Life Sci."},{"key":"D3FO04904C\/cit49\/1","doi-asserted-by":"crossref","first-page":"580980","DOI":"10.3389\/fcimb.2020.580980","volume":"10","author":"Xu","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D3FO04904C\/cit50\/1","first-page":"1058","volume":"89","author":"Sciarretta","year":"1994","journal-title":"Am. J. Gastroenterol."},{"key":"D3FO04904C\/cit51\/1","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.cgh.2012.05.006","volume":"10","author":"Wong","year":"2012","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"D3FO04904C\/cit52\/1","doi-asserted-by":"crossref","first-page":"20436","DOI":"10.1038\/s41598-020-77374-7","volume":"10","author":"Sagar","year":"2020","journal-title":"Sci. Rep."},{"key":"D3FO04904C\/cit53\/1","doi-asserted-by":"crossref","first-page":"729346","DOI":"10.3389\/fcimb.2021.729346","volume":"11","author":"Xiao","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D3FO04904C\/cit54\/1","doi-asserted-by":"crossref","first-page":"5134","DOI":"10.3748\/wjg.v25.i34.5134","volume":"25","author":"Zhao","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"D3FO04904C\/cit55\/1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1038\/s41396-021-01123-5","volume":"16","author":"Han","year":"2022","journal-title":"ISME J."},{"key":"D3FO04904C\/cit56\/1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.014","author":"Palsson","year":"2016","journal-title":"Gastroenterology"},{"key":"D3FO04904C\/cit57\/1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.3390\/metabo11070440","volume":"11","author":"Stenlund","year":"2021","journal-title":"Metabolites"},{"key":"D3FO04904C\/cit58\/1","doi-asserted-by":"crossref","first-page":"e1900243","DOI":"10.1002\/mnfr.201900243","volume":"63","author":"Cigliano","year":"2019","journal-title":"Mol. Nutr. Food Res."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/FO\/D3FO04904C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:55:45Z","timestamp":1782964545000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/15\/7\/3692-3708\/809812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":58,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,4,2]]}},"URL":"https:\/\/doi.org\/10.1039\/d3fo04904c","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}