{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:10:53Z","timestamp":1793502653574,"version":"4.5.0"},"reference-count":59,"publisher":"Royal Society of Chemistry (RSC)","issue":"6","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"am","delay-in-days":388,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<jats:p>A bio-inspired microfluidic device based on the structure of uterotubal junction (UTJ) is proposed which can separate motile sperms with enhanced DNA integrity.<\/jats:p>","DOI":"10.1039\/d3lc00893b","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T03:45:34Z","timestamp":1705981534000},"page":"1636-1647","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Bio-inspired progressive motile sperm separation using joint rheotaxis and boundary-following behavior"],"prefix":"10.1039","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5539-3074","authenticated-orcid":false,"given":"Mohammadjavad","family":"Bouloorchi Tabalvandani","sequence":"first","affiliation":[{"name":"MEMS Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Javadizadeh","sequence":"additional","affiliation":[{"name":"MEMS Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1647-7052","authenticated-orcid":false,"given":"Majid","family":"Badieirostami","sequence":"additional","affiliation":[{"name":"MEMS Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3LC00893B\/cit1\/1","first-page":"1","volume-title":"Infertility prevalence estimates 1990\u20132021","author":"WHO","year":"2023","unstructured":"WHO ,  Infertility prevalence estimates 1990\u20132021 ,  2023 ,  pp. 1\u201398"},{"key":"D3LC00893B\/cit2\/1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0140-6736(20)32667-2","volume":"397","author":"Agarwal","year":"2021","journal-title":"Lancet"},{"key":"D3LC00893B\/cit3\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.2021.4788","volume":"326","author":"Carson","year":"2021","journal-title":"JAMA, J. Am. Med. Assoc."},{"key":"D3LC00893B\/cit4\/1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2147\/tcrm.2006.2.4.355","volume":"2","author":"Wang","year":"2006","journal-title":"Ther. Clin. Risk Manage."},{"key":"D3LC00893B\/cit5\/1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1017\/CBO9780511919244.019","volume-title":"The Subfertility Handbook: A Clinician's Guide","author":"Thouas","year":"2010","unstructured":"G. A.Thouas  and  D. K.Gardner , in  The Subfertility Handbook: A Clinician's Guide , ed.  G. Kovacs ,  Cambridge University Press ,  Melbourne , 2nd edn,  2010 , ch. 18,  pp. 193\u2013210"},{"key":"D3LC00893B\/cit6\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/humupd\/dmp003","volume":"15","author":"Aboulghar","year":"2009","journal-title":"Hum. Reprod. Update"},{"key":"D3LC00893B\/cit7\/1","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3389\/fcell.2019.00298","volume":"7","author":"Oseguera-L\u00f3pez","year":"2019","journal-title":"Front. Cell Dev. Biol."},{"key":"D3LC00893B\/cit8\/1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fertnstert.2005.08.024","volume":"85","author":"Nallella","year":"2006","journal-title":"Fertil. Steril."},{"key":"D3LC00893B\/cit9\/1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/humrep\/deh545","volume":"20","author":"Berkovitz","year":"2005","journal-title":"Hum. Reprod."},{"key":"D3LC00893B\/cit10\/1","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1007\/s10815-011-9611-z","volume":"28","author":"Lazaros","year":"2011","journal-title":"J. Assist. Reprod. Genet."},{"key":"D3LC00893B\/cit11\/1","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s10815-011-9631-8","volume":"28","author":"Shamsi","year":"2011","journal-title":"J. Assist. Reprod. Genet."},{"key":"D3LC00893B\/cit12\/1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/1477-7827-1-108","volume":"1","author":"Henkel","year":"2003","journal-title":"Reprod. Biol. Endocrinol."},{"key":"D3LC00893B\/cit13\/1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1477-7827-12-121","volume":"12","author":"Malvezzi","year":"2014","journal-title":"Reprod. Biol. Endocrinol."},{"key":"D3LC00893B\/cit14\/1","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/S0090-4295(00)00770-6","volume":"56","author":"Zini","year":"2000","journal-title":"Urology"},{"key":"D3LC00893B\/cit15\/1","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.1039\/D0LC00457J","volume":"20","author":"Gai","year":"2020","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit16\/1","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.3390\/jcm9123976","volume":"9","author":"Pacheco","year":"2020","journal-title":"J. Clin. Med."},{"key":"D3LC00893B\/cit17\/1","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1097\/01.ogx.0000889884.68114.78","volume":"77","author":"West","year":"2022","journal-title":"Obstet. Gynecol. Surv."},{"key":"D3LC00893B\/cit18\/1","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1039\/c3lc51254a","volume":"14","author":"Nosrati","year":"2014","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit19\/1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/humupd\/dmv042","volume":"21","author":"Sakkas","year":"2015","journal-title":"Hum. Reprod. Update"},{"key":"D3LC00893B\/cit20\/1","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/nrm1893","volume":"7","author":"Eisenbach","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"D3LC00893B\/cit21\/1","doi-asserted-by":"crossref","first-page":"628","DOI":"10.4103\/1008-682X.154308","volume":"17","author":"Cerezales","year":"2015","journal-title":"Asian J. Androl."},{"key":"D3LC00893B\/cit22\/1","doi-asserted-by":"crossref","first-page":"e2108887118","DOI":"10.1073\/pnas.2108887118","volume":"118","author":"Suarez","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3LC00893B\/cit23\/1","doi-asserted-by":"crossref","first-page":"e02403","DOI":"10.7554\/eLife.02403","volume":"3","author":"Kantsler","year":"2014","journal-title":"eLife"},{"key":"D3LC00893B\/cit24\/1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1530\/REP-20-0364","volume":"161","author":"Romero-Aguirregomezcorta","year":"2021","journal-title":"Reproduction"},{"key":"D3LC00893B\/cit25\/1","first-page":"161","volume":"4","author":"Huang","year":"2023","journal-title":"Eng. Regen."},{"key":"D3LC00893B\/cit26\/1","doi-asserted-by":"crossref","first-page":"e20220006","DOI":"10.1002\/SMMD.20220006","volume":"1","author":"Zhu","year":"2022","journal-title":"Smart Medicine"},{"key":"D3LC00893B\/cit27\/1","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.1039\/D1LC00091H","volume":"21","author":"Yaghoobi","year":"2021","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit28\/1","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1039\/D0LC01182G","volume":"21","author":"Simchi","year":"2021","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit29\/1","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1038\/s41598-023-28315-7","volume":"13","author":"Heydari","year":"2023","journal-title":"Sci. Rep."},{"key":"D3LC00893B\/cit30\/1","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1039\/D2LC01190E","volume":"23","author":"Zeaei","year":"2023","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit31\/1","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1039\/D0LC00845A","volume":"21","author":"Yan","year":"2021","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit32\/1","doi-asserted-by":"crossref","first-page":"8272","DOI":"10.1073\/pnas.1800819115","volume":"115","author":"Zaferani","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3LC00893B\/cit33\/1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s13534-022-00229-9","volume":"12","author":"Mane","year":"2022","journal-title":"Biomed. Eng. Lett."},{"key":"D3LC00893B\/cit34\/1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/humupd\/dmi047","volume":"12","author":"Suarez","year":"2006","journal-title":"Hum. Reprod. Update"},{"key":"D3LC00893B\/cit35\/1","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1095\/biolreprod.104.028647","volume":"71","author":"Nakanishi","year":"2004","journal-title":"Biol. Reprod."},{"key":"D3LC00893B\/cit36\/1","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1039\/C3LC51297E","volume":"14","author":"Tung","year":"2014","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit37\/1","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.1039\/D3LC00037K","volume":"23","author":"Dadkhah","year":"2023","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit38\/1","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1039\/D1AN02311J","volume":"147","author":"Sharma","year":"2022","journal-title":"Analyst"},{"key":"D3LC00893B\/cit39\/1","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1039\/C9LC00209J","volume":"19","author":"Riordon","year":"2019","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit40\/1","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1039\/C6LC00490C","volume":"16","author":"Eamer","year":"2016","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit41\/1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s41378-023-00501-7","volume":"9","author":"Vasilescu","year":"2023","journal-title":"Microsyst. Nanoeng."},{"key":"D3LC00893B\/cit42\/1","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1039\/D0LC00874E","volume":"21","author":"Xiao","year":"2021","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit43\/1","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1039\/D2LC00997H","volume":"23","author":"Nath","year":"2023","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit44\/1","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1093\/humrep\/dei024","volume":"20","author":"Ainsworth","year":"2005","journal-title":"Hum. Reprod."},{"key":"D3LC00893B\/cit45\/1","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1007\/s00449-012-0838-6","volume":"36","author":"Rosales-Cruzaley","year":"2013","journal-title":"Bioprocess Biosyst. Eng."},{"key":"D3LC00893B\/cit46\/1","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1039\/C6LC00256K","volume":"16","author":"De Wagenaar","year":"2016","journal-title":"Lab Chip"},{"key":"D3LC00893B\/cit47\/1","doi-asserted-by":"crossref","first-page":"679","DOI":"10.3390\/bios12090679","volume":"12","author":"Kruit","year":"2022","journal-title":"Biosensors"},{"key":"D3LC00893B\/cit48\/1","doi-asserted-by":"crossref","first-page":"E6","DOI":"10.1017\/flo.2022.30","volume":"3","author":"Castro","year":"2023","journal-title":"Flow"},{"key":"D3LC00893B\/cit49\/1","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/nrurol.2017.175","volume":"14","author":"Nosrati","year":"2017","journal-title":"Nat. Rev. Urol."},{"key":"D3LC00893B\/cit50\/1","doi-asserted-by":"crossref","first-page":"8007","DOI":"10.1073\/pnas.1202934109","volume":"109","author":"Denissenko","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D3LC00893B\/cit51\/1","doi-asserted-by":"crossref","first-page":"eaav2111","DOI":"10.1126\/sciadv.aav2111","volume":"5","author":"Zaferani","year":"2019","journal-title":"Sci. Adv."},{"key":"D3LC00893B\/cit52\/1","doi-asserted-by":"crossref","first-page":"20160633","DOI":"10.1098\/rsif.2016.0633","volume":"13","author":"Ishimoto","year":"2016","journal-title":"J. R. Soc., Interface"},{"key":"D3LC00893B\/cit53\/1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1002\/aja.1001600309","volume":"160","author":"Gaddum-Rosse","year":"1981","journal-title":"Am. J. Anat."},{"key":"D3LC00893B\/cit54\/1","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.cub.2013.02.007","volume":"23","author":"Miki","year":"2013","journal-title":"Curr. Biol."},{"key":"D3LC00893B\/cit55\/1","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1038\/s41467-017-01462-y","volume":"8","author":"Saggiorato","year":"2017","journal-title":"Nat. Commun."},{"key":"D3LC00893B\/cit56\/1","doi-asserted-by":"crossref","first-page":"108102","DOI":"10.1103\/PhysRevLett.114.108102","volume":"114","author":"Tung","year":"2015","journal-title":"Phys. Rev. Lett."},{"key":"D3LC00893B\/cit57\/1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1140\/epje\/s10189-021-00076-z","volume":"44","author":"Gong","year":"2021","journal-title":"Eur. Phys. J. E: Soft Matter Biol. Phys."},{"key":"D3LC00893B\/cit58\/1","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1093\/humrep\/17.12.3122","volume":"17","author":"Duran","year":"2002","journal-title":"Hum. Reprod."},{"key":"D3LC00893B\/cit59\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.fertnstert.2005.07.1327","volume":"85","author":"Muriel","year":"2006","journal-title":"Fertil. Steril."}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/LC\/D3LC00893B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:45:28Z","timestamp":1782942328000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/24\/6\/1636-1647\/811821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":59,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,3,12]]}},"URL":"https:\/\/doi.org\/10.1039\/d3lc00893b","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}