{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:02:37Z","timestamp":1788580957973,"version":"build-2803163510"},"reference-count":39,"publisher":"Royal Society of Chemistry (RSC)","issue":"1","license":[{"start":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T00:00:00Z","timestamp":1698624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81502688"],"award-info":[{"award-number":["81502688"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["KM201810025019"],"award-info":[{"award-number":["KM201810025019"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["KM202210025024"],"award-info":[{"award-number":["KM202210025024"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002799","name":"Capital Medical University","doi-asserted-by":"publisher","award":["16JL72"],"award-info":[{"award-number":["16JL72"]}],"id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002799","name":"Capital Medical University","doi-asserted-by":"publisher","award":["17JL67"],"award-info":[{"award-number":["17JL67"]}],"id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale Adv."],"abstract":"<jats:p>A liposome co-loaded with an antioxidant and anti-inflammatory drug EGCG and a lipid-efflux-promoting gene miR-223 is constructed to eliminate AS plaques effectively, and provide a novel strategy for the safe and efficient management of AS.<\/jats:p>","DOI":"10.1039\/d3na00369h","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T03:04:09Z","timestamp":1698635049000},"page":"221-232","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Multifunctional liposomes Co-encapsulating epigallocatechin-3-gallate (EGCG) and miRNA for atherosclerosis lesion elimination"],"prefix":"10.1039","volume":"6","author":[{"given":"Dandan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danni","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoqi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxuan","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Huo","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7056-4755","authenticated-orcid":false,"given":"Chunying","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmaceutical Science, Capital Medical University, No. 10 Youanmenwai Street, Fengtai, Beijing, 100069, People's Republic of China"},{"name":"Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing, 10069, People's Republic of China"},{"name":"Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, 10069, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D3NA00369H\/cit1\/1","doi-asserted-by":"crossref","first-page":"100694","DOI":"10.1016\/j.blre.2020.100694","volume":"45","author":"Lordan","year":"2021","journal-title":"Blood Rev."},{"issue":"1","key":"D3NA00369H\/cit2\/1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/s41572-019-0106-z","volume":"5","author":"Libby","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"4","key":"D3NA00369H\/cit3\/1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.tcm.2014.10.015","volume":"25","author":"Finkel","year":"2015","journal-title":"Trends Cardiovasc. Med."},{"key":"D3NA00369H\/cit4\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1161\/01.CIR.0000131514.71167.2e","volume":"109","author":"Paoletti","year":"2004","journal-title":"Circulation"},{"issue":"3","key":"D3NA00369H\/cit5\/1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.smim.2015.03.013","volume":"27","author":"Viola","year":"2015","journal-title":"Semin. Immunol."},{"key":"D3NA00369H\/cit6\/1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.atherosclerosis.2018.07.014","volume":"276","author":"Raggi","year":"2018","journal-title":"Atherosclerosis"},{"issue":"10","key":"D3NA00369H\/cit7\/1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/nri3520","volume":"13","author":"Moore","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"D3NA00369H\/cit8\/1","doi-asserted-by":"crossref","first-page":"119550","DOI":"10.1016\/j.biomaterials.2019.119550","volume":"226","author":"Kim","year":"2020","journal-title":"Biomaterials"},{"key":"D3NA00369H\/cit9\/1","doi-asserted-by":"crossref","first-page":"2303150","DOI":"10.1002\/adfm.202303150","volume":"33","author":"Chenxing Fu","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"D3NA00369H\/cit10\/1","doi-asserted-by":"crossref","first-page":"8563845","DOI":"10.1155\/2019\/8563845","volume":"2019","author":"Marchio","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"4","key":"D3NA00369H\/cit11\/1","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1161\/CIRCRESAHA.116.309326","volume":"120","author":"F\u00f6rstermann","year":"2017","journal-title":"Circ. Res."},{"key":"D3NA00369H\/cit12\/1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.biochi.2015.12.014","volume":"125","author":"Salvayre","year":"2016","journal-title":"Biochimie"},{"issue":"6","key":"D3NA00369H\/cit13\/1","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.3390\/ijms22063037","volume":"22","author":"Cheng","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D3NA00369H\/cit14\/1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.foodchem.2018.08.086","volume":"272","author":"Liu","year":"2019","journal-title":"Food Chem."},{"issue":"14","key":"D3NA00369H\/cit15\/1","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.3390\/molecules25143146","volume":"25","author":"Almatroodi","year":"2020","journal-title":"Molecules"},{"key":"D3NA00369H\/cit16\/1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jnutbio.2015.11.001","volume":"30","author":"Zhang","year":"2016","journal-title":"J. Nutr. Biochem."},{"key":"D3NA00369H\/cit17\/1","first-page":"103732","volume":"62","author":"Wenzhong Dai","year":"2020","journal-title":"J. Funct. Foods"},{"issue":"3","key":"D3NA00369H\/cit18\/1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1590\/s1679-45082017rb4024","volume":"15","author":"Gon\u00e7alves","year":"2017","journal-title":"Einstein"},{"issue":"3","key":"D3NA00369H\/cit19\/1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1161\/CIRCRESAHA.111.247916","volume":"110","author":"van Rooij","year":"2012","journal-title":"Circ. Res."},{"issue":"40","key":"D3NA00369H\/cit20\/1","doi-asserted-by":"crossref","first-page":"14518","DOI":"10.1073\/pnas.1215767111","volume":"111","author":"Vickers","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"D3NA00369H\/cit21\/1","doi-asserted-by":"crossref","first-page":"11554","DOI":"10.1021\/acsanm.1c02009","volume":"4","author":"Zhaojun Li","year":"2021","journal-title":"ACS Appl. Nano Mater."},{"issue":"2","key":"D3NA00369H\/cit22\/1","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1021\/acsnano.0c00245","volume":"14","author":"Kanthi","year":"2020","journal-title":"ACS Nano"},{"issue":"6","key":"D3NA00369H\/cit23\/1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.ajps.2021.05.003","volume":"16","author":"Pan","year":"2021","journal-title":"Asian J. Pharm. Sci."},{"key":"D3NA00369H\/cit24\/1","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/j.cclet.2021.10.055","volume":"33","author":"Yilin Song","year":"2022","journal-title":"Chin. Chem. Lett."},{"issue":"14","key":"D3NA00369H\/cit25\/1","doi-asserted-by":"crossref","first-page":"e2000465","DOI":"10.1002\/adhm.202000465","volume":"9","author":"Darwitan","year":"2020","journal-title":"Adv. Healthc. Mater."},{"issue":"9","key":"D3NA00369H\/cit26\/1","doi-asserted-by":"crossref","first-page":"8885","DOI":"10.1021\/acsnano.5b02611","volume":"9","author":"Kheirolomoom","year":"2015","journal-title":"ACS Nano"},{"issue":"8","key":"D3NA00369H\/cit27\/1","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/o59-099","volume":"37","author":"Bligh","year":"1959","journal-title":"Can. J. Biochem. Physiol."},{"issue":"4","key":"D3NA00369H\/cit28\/1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.3390\/cells12040522","volume":"12","author":"Blagov","year":"2023","journal-title":"Cells"},{"issue":"2","key":"D3NA00369H\/cit29\/1","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.jacc.2017.05.034","volume":"70","author":"Sack","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"issue":"7","key":"D3NA00369H\/cit30\/1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.2116\/analsci.18P014","volume":"34","author":"Sirivibulkovit","year":"2018","journal-title":"Anal. Sci."},{"issue":"6","key":"D3NA00369H\/cit31\/1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.cytogfr.2015.04.003","volume":"26","author":"Ramji","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"D3NA00369H\/cit32\/1","first-page":"101445","author":"Jiaoyu Ren","year":"2022","journal-title":"Mater. Today"},{"issue":"1","key":"D3NA00369H\/cit33\/1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1161\/CIRCRESAHA.121.319120","volume":"131","author":"Nguyen","year":"2022","journal-title":"Circ. Res."},{"issue":"2","key":"D3NA00369H\/cit34\/1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0092-8674(00)81574-3","volume":"93","author":"Nagy","year":"1998","journal-title":"Cell"},{"issue":"11","key":"D3NA00369H\/cit35\/1","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1038\/nrd3578","volume":"10","author":"Lobatto","year":"2011","journal-title":"Nat. Rev. Drug Discov."},{"issue":"2","key":"D3NA00369H\/cit36\/1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1161\/CIRCRESAHA.112.268144","volume":"111","author":"Quillard","year":"2012","journal-title":"Circ. Res."},{"issue":"12","key":"D3NA00369H\/cit37\/1","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1161\/ATVBAHA.107.151456","volume":"27","author":"Woodfin","year":"2007","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"issue":"1","key":"D3NA00369H\/cit38\/1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/labinvest.2016.116","volume":"97","author":"Chistiakov","year":"2017","journal-title":"Lab. Invest."},{"issue":"22","key":"D3NA00369H\/cit39\/1","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1093\/eurheartj\/ehv759","volume":"37","author":"Tousoulis","year":"2016","journal-title":"Eur. Heart J."}],"container-title":["Nanoscale Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/NA\/D3NA00369H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:25:32Z","timestamp":1782879932000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/na\/article\/6\/1\/221-232\/814243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,12,19]]}},"URL":"https:\/\/doi.org\/10.1039\/d3na00369h","relation":{},"ISSN":["2516-0230"],"issn-type":[{"value":"2516-0230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}