{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T21:52:15Z","timestamp":1782856335608,"version":"3.54.5"},"reference-count":33,"publisher":"Royal Society of Chemistry (RSC)","issue":"45","license":[{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"am","delay-in-days":669,"URL":"http:\/\/rsc.li\/journals-terms-of-use#chorus"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2117318 (NMR)"],"award-info":[{"award-number":["2117318 (NMR)"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1048655 (MS)"],"award-info":[{"award-number":["1048655 (MS)"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1531454 (MS)"],"award-info":[{"award-number":["1531454 (MS)"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000165","name":"Division of Chemistry","doi-asserted-by":"publisher","award":["1954041"],"award-info":[{"award-number":["1954041"]}],"id":[{"id":"10.13039\/100000165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM109288"],"award-info":[{"award-number":["GM109288"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Org. Biomol. Chem."],"abstract":"<jats:p>Using PEGylated Dmoc (pDmoc) phosphoramidites for oligodeoxynucleotide (ODN) synthesis increases the solubility of ODN on solid support and enables the synthesis of longer sensitive ODNs.<\/jats:p>","DOI":"10.1039\/d3ob01495a","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T11:02:05Z","timestamp":1698750125000},"page":"9005-9010","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["PEGylated Dmoc phosphoramidites for sensitive oligodeoxynucleotide synthesis"],"prefix":"10.1039","volume":"21","author":[{"given":"Komal","family":"Chillar","sequence":"first","affiliation":[{"name":"Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yipeng","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Apostle","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6523-7557","authenticated-orcid":false,"given":"Shiyue","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D3OB01495A\/cit1\/1","doi-asserted-by":"crossref","first-page":"7110","DOI":"10.1002\/anie.201201193","volume":"51","author":"Carell","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3OB01495A\/cit2a\/1","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.3390\/v12121377","volume":"12","author":"Pei","year":"2020","journal-title":"Viruses"},{"key":"D3OB01495A\/cit2b\/1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/s41576-021-00348-6","volume":"22","author":"Oh","year":"2021","journal-title":"Nat. Rev. Genet."},{"key":"D3OB01495A\/cit3a\/1","doi-asserted-by":"crossref","first-page":"9189","DOI":"10.1007\/s11033-020-05963-w","volume":"47","author":"Karthiya","year":"2020","journal-title":"Mol. Biol. Rep."},{"key":"D3OB01495A\/cit3b\/1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.omtn.2020.01.037","volume":"20","author":"Jin","year":"2020","journal-title":"Mol. Ther.\u2013Nucleic Acids"},{"key":"D3OB01495A\/cit4\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s13059-021-02578-7","volume":"23","author":"Wang","year":"2022","journal-title":"Genome Biol."},{"key":"D3OB01495A\/cit5\/1","doi-asserted-by":"publisher","DOI":"10.1002\/cpnc.1032","volume":"69","author":"Meher","year":"2017","journal-title":"Curr. Protoc. Nucleic Acid Chem."},{"key":"D3OB01495A\/cit6a\/1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0040-4039(00)95646-6","volume":"28","author":"Schulhof","year":"1987","journal-title":"Tetrahedron Lett."},{"key":"D3OB01495A\/cit6b\/1","doi-asserted-by":"crossref","first-page":"6931","DOI":"10.1021\/ja00094a056","volume":"116","author":"Matray","year":"1994","journal-title":"J. Am. Chem. Soc."},{"key":"D3OB01495A\/cit6c\/1","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1021\/ja00161a006","volume":"112","author":"Hayakawa","year":"1990","journal-title":"J. Am. Chem. Soc."},{"key":"D3OB01495A\/cit6d\/1","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1016\/S0040-4020(01)92195-7","volume":"48","author":"Eritja","year":"1992","journal-title":"Tetrahedron"},{"key":"D3OB01495A\/cit6e\/1","doi-asserted-by":"crossref","first-page":"4583","DOI":"10.1002\/1099-0690(200112)2001:24<4583::AID-EJOC4583>3.0.CO;2-R","author":"Wada","year":"2001","journal-title":"Eur. J. Org. Chem."},{"key":"D3OB01495A\/cit6f\/1","doi-asserted-by":"crossref","first-page":"3487","DOI":"10.1021\/jacs.1c11985","volume":"144","author":"Bartee","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D3OB01495A\/cit6g\/1","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.1021\/acschembio.7b00734","volume":"12","author":"Sinclair","year":"2017","journal-title":"ACS Chem. Biol."},{"key":"D3OB01495A\/cit7\/1","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1021\/acs.orglett.6b01878","volume":"18","author":"Lin","year":"2016","journal-title":"Org. Lett."},{"key":"D3OB01495A\/cit8a\/1","doi-asserted-by":"crossref","first-page":"13374","DOI":"10.1021\/acs.joc.9b01527","volume":"84","author":"Shahsavari","year":"2019","journal-title":"J. Org. Chem."},{"key":"D3OB01495A\/cit8b\/1","doi-asserted-by":"publisher","DOI":"10.1002\/cpnc.1111","volume":"82","author":"Fang","year":"2020","journal-title":"Curr. Protoc. Nucleic Acid Chem."},{"key":"D3OB01495A\/cit8c\/1","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.3762\/bjoc.15.108","volume":"15","author":"Shahsavari","year":"2019","journal-title":"Beilstein J. Org. Chem."},{"key":"D3OB01495A\/cit8d\/1","doi-asserted-by":"crossref","first-page":"8857","DOI":"10.1002\/slct.201801484","volume":"3","author":"Halami","year":"2018","journal-title":"ChemistrySelect"},{"key":"D3OB01495A\/cit9\/1","doi-asserted-by":"crossref","first-page":"8714","DOI":"10.1039\/D2NJ03845E","volume":"47","author":"Chillar","year":"2023","journal-title":"New J. Chem."},{"key":"D3OB01495A\/cit10a\/1","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.1002\/slct.201700364","volume":"2","author":"Shahsavari","year":"2017","journal-title":"ChemistrySelect"},{"key":"D3OB01495A\/cit10b\/1","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.3762\/bjoc.14.149","volume":"14","author":"Shahsavari","year":"2018","journal-title":"Beilstein J. Org. Chem."},{"key":"D3OB01495A\/cit11\/1","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1039\/C5GC01762A","volume":"18","author":"Pokharel","year":"2016","journal-title":"Green Chem."},{"key":"D3OB01495A\/cit12a\/1","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.3233\/JAD-220564","volume":"90","author":"Ma","year":"2022","journal-title":"J. Alzheimer's Dis."},{"key":"D3OB01495A\/cit12b\/1","doi-asserted-by":"crossref","first-page":"9189","DOI":"10.1007\/s11033-020-05963-w","volume":"47","author":"Karthiya","year":"2020","journal-title":"Mol. Biol. Rep."},{"key":"D3OB01495A\/cit13\/1","doi-asserted-by":"crossref","first-page":"151306","DOI":"10.1016\/j.tetlet.2019.151306","volume":"60","author":"Halami","year":"2019","journal-title":"Tetrahedron Lett."},{"key":"D3OB01495A\/cit14\/1","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1042\/EBC20200059","volume":"65","author":"Garner","year":"2021","journal-title":"Essays Biochem."},{"key":"D3OB01495A\/cit15\/1","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1021\/acssynbio.3c00026","volume":"12","author":"Chai","year":"2023","journal-title":"ACS Synth. Biol."},{"key":"D3OB01495A\/cit16\/1","doi-asserted-by":"crossref","first-page":"103458","DOI":"10.1016\/j.drudis.2022.103458","volume":"28","author":"Aljabali","year":"2023","journal-title":"Drug Discovery Today"},{"key":"D3OB01495A\/cit17\/1","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/s41576-019-0125-3","volume":"20","author":"Ceze","year":"2019","journal-title":"Nat. Rev. Genet."},{"key":"D3OB01495A\/cit18a\/1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3390\/genes14020382","volume":"14","author":"Hori","year":"2023","journal-title":"Genes"},{"key":"D3OB01495A\/cit18b\/1","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.3390\/genes13112050","volume":"13","author":"Zhang","year":"2022","journal-title":"Genes"},{"key":"D3OB01495A\/cit19\/1","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.7717\/peerj-achem.20","volume":"4","author":"Komal Chillar","year":"2022","journal-title":"PeerJ Anal. Chem."}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/OB\/D3OB01495A","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/OB\/D3OB01495A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:43:01Z","timestamp":1782852181000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ob\/article\/21\/45\/9005-9010\/819981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":33,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2023,11,22]]}},"URL":"https:\/\/doi.org\/10.1039\/d3ob01495a","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}